Publications

Ornella MOLTEDO Publications


2024
Articolo in rivista
Multiomic Profiling and Neuroprotective Bioactivity of Salvia Hairy Root-Derived Extracellular Vesicles in a Cellular Model of Parkinson's Disease
INTERNATIONAL JOURNAL OF NANOMEDICINE. Vol. 19. Pag.9373-9393
ISSN:1178-2013.
Vestuto, Vincenzo; Conte, Marisa; Vietri, Mariapia; Mensitieri, Francesca; Santoro, Valentina; Di Muro, Anna; Alfieri, Mariaevelina; Moros, Maria; Miranda, Maria Rosaria; Amante, Chiara; Delli Carri, Matteo; Campiglia, Pietro; Dal Piaz, Fabrizio; Del Gaudio, Pasquale; De Tommasi, Nunziatina; Leone, Antonietta; Moltedo, Ornella; Pepe, Giacomo; Cappetta, Elisa; Ambrosone, Alfredo
Digital Object Identifier (DOI): 10.2147/IJN.S479959
Codice identificativo SCOPUS: 2-s2.0-85204418948
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2024
Articolo in rivista
Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress
ANTIOXIDANTS. Vol. 13. Pag.1-30
ISSN:2076-3921.
Miranda, Maria Rosaria; Basilicata, Manuela Giovanna; Vestuto, Vincenzo; Aquino, Giovanna; Marino, Pasquale; Salviati, Emanuela; Ciaglia, Tania; Domínguez-Rodríguez, Gloria; Moltedo, Ornella; Campiglia, Pietro; Pepe, Giacomo; Manfra, Michele
Digital Object Identifier (DOI): 10.3390/antiox13060708
Codice identificativo SCOPUS: 2-s2.0-85197913626
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2023
Articolo in rivista
Myogenesis in C2C12 Cells Requires Phosphorylation of ATF6α by p38 MAPK
BIOMEDICINES. Vol. 11. Pag.1457-1477
ISSN:2227-9059.
Pagliara, Valentina; Amodio, Giuseppina; Vestuto, Vincenzo; Franceschelli, Silvia; Russo, Nicola Antonino; Cirillo, Vittorio; Mottola, Giovanna; Remondelli, Paolo; Moltedo, Ornella
Digital Object Identifier (DOI): 10.3390/biomedicines11051457
Codice identificativo ISI: WOS:001011293400001
Codice identificativo SCOPUS: 2-s2.0-85160705501
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2023
Articolo in rivista
The Ion Channels Involved in Oxidative Stress-Related Gastrointestinal Diseases
OXYGEN. Vol. 3. Pag.336-365
ISSN:2673-9801.
Miranda, Maria Rosaria; Vestuto, Vincenzo; Moltedo, Ornella; Manfra, Michele; Campiglia, Pietro; Pepe, Giacomo
Digital Object Identifier (DOI): 10.3390/oxygen3030022
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2022
Articolo in rivista
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK
BIOMEDICINES. Vol. 10. Pag.2009-2028
ISSN:2227-9059.
Vestuto, V.; Amodio, G.; Pepe, G.; Basilicata, M. G.; Belvedere, R.; Napolitano, E.; Guarnieri, D.; Pagliara, V.; Paladino, S.; Rodriquez, M.; Bertamino, A.; Campiglia, P.; Remondelli, P.; Moltedo, O.
Digital Object Identifier (DOI): 10.3390/biomedicines10082009
Codice identificativo ISI: WOS:000847083800001
Codice identificativo SCOPUS: 2-s2.0-85137372342
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2022
Articolo in rivista
New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol. 24. Pag.185-185
ISSN:1422-0067.
Vestuto, Vincenzo; Di Sarno, Veronica; Musella, Simona; Di Dona, Giorgio; Moltedo, Ornella; Gomez-Monterrey, Isabel Maria; Bertamino, Alessia; Ostacolo, Carmine; Campiglia, Pietro; Ciaglia, Tania
Digital Object Identifier (DOI): 10.3390/ijms24010185
Codice identificativo ISI: WOS:000909155300001
Codice identificativo SCOPUS: 2-s2.0-85145980610
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2022
Articolo in rivista
ER exit pathways and the control of proteostasis: Crucial role of the UPR, COPII, and ER-phagy in the secretory pathway
BIOCELL. Pag.1131-1137
ISSN:0327-9545.
Amodio, Giuseppina; Pagliara, Valentina; Remondelli, Paolo; Moltedo, Ornella
Digital Object Identifier (DOI): 10.32604/biocell.2022.018638
Codice identificativo ISI: WOS:000742633900002
Codice identificativo SCOPUS: 2-s2.0-85122896529
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2021
Articolo in rivista
Structural and Functional Significance of the Endoplasmic Reticulum Unfolded Protein Response Transducers and Chaperones at the Mitochondria–ER Contacts: A Cancer Perspective
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. Vol. 9. Pag.1-16
ISSN:2296-634X.
Amodio, Giuseppina; Pagliara, Valentina; Moltedo, Ornella; Remondelli, Paolo
Digital Object Identifier (DOI): 10.3389/fcell.2021.641194
Codice identificativo ISI: WOS:000638174400001
Codice identificativo SCOPUS: 2-s2.0-85103878942
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2021
Articolo in rivista
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. Vol. 226. Pag.113863-113863
ISSN:0223-5234.
Di Sarno, V.; Lauro, G.; Musella, S.; Ciaglia, T.; Vestuto, V.; Sala, M.; Scala, M. C.; Smaldone, G.; Di Matteo, F.; Novi, S.; Tecce, M. F.; Moltedo, O.; Bifulco, G.; Campiglia, P.; Gomez-Monterrey, I. M.; Snoeck, R.; Andrei, G.; Ostacolo, C.; Bertamino, A.
Digital Object Identifier (DOI): 10.1016/j.ejmech.2021.113863
Codice identificativo ISI: WOS:000703119000042
Codice identificativo SCOPUS: 2-s2.0-85115784362
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2020
Articolo in rivista
Binding of the Anti-FIV Peptide C8 to Differently Charged Membrane Models: From First Docking to Membrane Tubulation
FRONTIERS IN CHEMISTRY. Vol. 8. Pag.493-493
ISSN:2296-2646.
Di Marino, D.; Bruno, A.; Grimaldi, M.; Scrima, M.; Stillitano, I.; Amodio, G.; Della Sala, G.; Romagnoli, A.; De Santis, A.; Moltedo, O.; Remondelli, P.; Boccia, G.; D'Errico, G.; D'Ursi, A. M.; Limongelli, V.
Digital Object Identifier (DOI): 10.3389/fchem.2020.00493
Codice identificativo ISI: WOS:000615287400001
Codice identificativo SCOPUS: 2-s2.0-85087769758
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2020
Articolo in rivista
NMR Structure of the FIV gp36 C-Terminal Heptad Repeat and Membrane-Proximal External Region.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol. 21. Pag.2037-2037
ISSN:1661-6596.
Grimaldi, M; Buonocore, M; Scrima, M; Stillitano, I; D'Errico, G; Santoro, A; Amodio, G; Eletto, D; Gloria, A; Russo, T; Moltedo, O; Remondelli, P; Tosco, A; Wienk, Hlj; D'Ursi, Am.
Digital Object Identifier (DOI): 10.3390/ijms21062037
Codice identificativo ISI: WOS:000529890200133
Codice identificativo SCOPUS: 2-s2.0-85081695625
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2020
Articolo in rivista
Bioactive Ent-Kaurane Diterpenes Oridonin and Irudonin Prevent Cancer Cells Migration by Interacting with the Actin Cytoskeleton Controller Ezrin
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol. 21. Pag.1-19
ISSN:1422-0067.
Pagliara, Valentina; Donadio, Giuliana; De Tommasi, Nunziatina; Amodio, Giuseppina; Remondelli, Paolo; Moltedo, Ornella; Dal Piaz, Fabrizio
Digital Object Identifier (DOI): 10.3390/ijms21197186
Codice identificativo ISI: WOS:000586579900001
Codice identificativo SCOPUS: 2-s2.0-85091927460
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2019
Articolo in rivista
PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
FRONTIERS IN NEUROSCIENCE. Vol. 13. Pag.1-14
ISSN:1662-453X.
Amodio, Giuseppina; Moltedo, Ornella; Fasano, Dominga; Zerillo, Lucrezia; Oliveti, Marco; Di Pietro, Paola; Faraonio, Raffaella; Barone, Paolo; Pellecchia, Maria Teresa; De Rosa, Anna; De Michele, Giuseppe; Polishchuk, Elena; Polishchuk, Roman; Bonifati, Vincenzo; Nitsch, Lucio; Pierantoni, Giovanna Maria; Renna, Maurizio; Criscuolo, Chiara; Paladino, Simona; Remondelli, Paolo
Versione online
Digital Object Identifier (DOI): 10.3389/fnins.2019.00673
Codice identificativo ISI: WOS:000473233000001
Codice identificativo SCOPUS: 2-s2.0-85068250696
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2018
Articolo in rivista
Targeting the Endoplasmic Reticulum Unfolded Protein Response to Counteract the Oxidative Stress-Induced Endothelial Dysfunction
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. Vol. 2018. Pag.1-13
ISSN:1942-0900.
Amodio, Giuseppina; Moltedo, Ornella; Faraonio, Raffaella; Remondelli, Paolo
Versione online
Digital Object Identifier (DOI): 10.1155/2018/4946289
Codice identificativo ISI: WOS:000428341600001
Codice identificativo SCOPUS: 2-s2.0-85045400429
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2018
Articolo in rivista
Alteration of endosomal trafficking is associated with early-onset parkinsonism caused by SYNJ1 mutations
CELL DEATH & DISEASE. Vol. 9. Pag.1-15
ISSN:2041-4889.
Fasano, Dominga; Parisi, Silvia; Pierantoni, Giovanna Maria; De Rosa, Anna; Picillo, Marina; Amodio, Giuseppina; Pellecchia, Maria Teresa; Barone, Paolo; Moltedo, Ornella; Bonifati, Vincenzo; De Michele, Giuseppe; Nitsch, Lucio; Remondelli, Paolo; Criscuolo, Chiara; Paladino, Simona
Digital Object Identifier (DOI): 10.1038/s41419-018-0410-7
Codice identificativo ISI: WOS:000427426100015
Codice identificativo SCOPUS: 2-s2.0-85045982881
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2018
Articolo in rivista
Structural basis of antiviral activity of peptides from MPER of FIV gp36
PLOS ONE. Vol. 13. Pag.e0204042-e0204050
ISSN:1932-6203.
Grimaldi, Manuela; Stillitano, Ilaria; Amodio, Giuseppina; Santoro, Angelo; Buonocore, Michela; Moltedo, Ornella; Remondelli, Paolo; D'Ursi, Anna Maria
Versione online
Digital Object Identifier (DOI): 10.1371/journal.pone.0204042
Codice identificativo ISI: WOS:000445329700020
Codice identificativo SCOPUS: 2-s2.0-85054023399
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2017
Articolo in rivista
miR-128 Is Implicated in stress Response by Targeting MAFG in Skeletal Muscle Cells
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. Pag.1-13
ISSN:1942-0994.
Rocco Caggiano, Fabio Cattaneo; Moltedo, Ornella; Esposito, Giovanni; Perrino, Cinzia; Trimarco, Bruno; Ammendola, Rosario; Faraonio, Raffaella
Versione online
Digital Object Identifier (DOI): 10.1155/2017/9308310
Codice identificativo ISI: WOS:000410230300001
Codice identificativo SCOPUS: 2-s2.0-85030625686
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2017
Articolo in rivista
Identification of Cysteine Ubiquitylation Sites on the Sec23A Protein of the COPII Complex Required for Vesicle Formation from the ER
THE OPEN BIOCHEMISTRY JOURNAL. Vol. 11. Pag.36-46
ISSN:1874-091X.
Amodio, Giuseppina; Margarucci, Luigi; Moltedo, Ornella; Casapullo, Agostino; Remondelli, Paolo
Digital Object Identifier (DOI): 10.2174/1874091X01711010036
Codice identificativo SCOPUS: 2-s2.0-85020395035
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2016
Articolo in rivista
Identification of a microRNA (miR-663a) induced by ER stress and its target gene PLOD3 by a combined microRNome and proteome approach
CELL BIOLOGY AND TOXICOLOGY. Pag.285-303
ISSN:0742-2091.
Amodio, Giuseppina; Sasso, Emanuele; D'Ambrosio, Chiara; Scaloni, Andrea; Moltedo, Ornella; Franceschelli, Silvia; Zambrano, Nicola; Remondelli, Paolo
Digital Object Identifier (DOI): 10.1007/s10565-016-9335-z
Codice identificativo ISI: WOS:000379985000004
Codice identificativo SCOPUS: 2-s2.0-84978374862
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2015
Abstract in Atti di convegno
Overexpression of hsa-miR-663a reduces expression of PLOD3 encoded LH3 protein and secretion of Collagen IV.
In: The biennal Congress of the Italian Association of cell Biology and Differentiation Pag.90-90
The biennal Congress of the Italian Association of cell Biology and Differentiation
Bologna 17-19 settembre 201\5
Amodio, Giuseppina; Moltedo, Ornella; Franceschelli, Silvia; Remondelli, Paolo
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2014
Abstract in Atti di convegno
Endoplasmic reticulum stress reduces COPII vesicles formation and modifies Sec23a cycling at ERESsG. Amodio1, O. Moltedo1, S. Franceschelli1, P. Remondelli2 1Dipartimento di Farmacia, Univ. of Salerno, Italy 2Dipartimento di Medicina e Chirurgia, Univ. of Salerno, Italy.
In: Membrane Traffiffiicking and Organelle Biogenesi Pag.11-11
Amodio, Giuseppina; Moltedo, Ornella; Franceschelli, Silvia; Remondelli, Paolo
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2013
Abstract in Atti di convegno
Sec23a as the key molecular target of ER Stress dependent modulation of COPII assemblingG. Amodio1, O. Moltedo1, V. Pecoraro1, P. Remondelli21Dipartimento di Farmacia, Univ. of Salerno, Italy2Dipartimento di Medicina e Chirurgia , Univ. of Salerno, Italy.
In: Sec23a as the key molecular target of ER Stress dependent modulation of COPII assembling Pag.13-13
Amodio, Giuseppina; Moltedo, Ornella; Verdiana, Pecoraro; Remondelli, Paolo
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2013
Articolo in rivista
Endoplasmic Reticulum stress reduces COPII vesicle formation and modifies Sec23a cycling at ERESs
FEBS LETTERS. Vol. 587. Pag.3261-3266
ISSN:0014-5793.
Amodio, Giuseppina; Venditti, R; De Matteis, Ma; Moltedo, Ornella; Pignataro, P; Remondelli, Paolo
Digital Object Identifier (DOI): 10.1016/j.febslet.2013.08.021
Codice identificativo ISI: WOS:000324472200016
Codice identificativo SCOPUS: 2-s2.0-84884280837
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2011
Articolo in rivista
In the Huh7 Hepatoma Cells Diclofenac and Indonethacin Activate Differently the Unfolded Protein Response and Induce ER Stress Apoptosis
THE OPEN BIOCHEMISTRY JOURNAL. Vol. 5. Pag.45-51
ISSN:1874-091X.
Franceschelli, Silvia; Moltedo, Ornella; Amodio, Giuseppina; Tajana, Gianfranco; Remondelli, Paolo
Digital Object Identifier (DOI): 10.2174/1874091X01105010045
Codice identificativo SCOPUS: 2-s2.0-80053441126
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2011
Articolo in rivista
Proteomic signatures in thapsigargin-treated hepatoma cells.
CHEMICAL RESEARCH IN TOXICOLOGY. Vol. 24. Pag.1215-1222
ISSN:0893-228X.
Amodio, Giuseppina; Moltedo, Ornella; Monteleone, F; D'Ambrosio, C; Scaloni, A; Remondelli, Paolo; Zambrano, N.
Digital Object Identifier (DOI): 10.1021/tx200109y
Codice identificativo ISI: WOS:000294076200003
Codice identificativo SCOPUS: 2-s2.0-80051733402
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2010
Articolo in rivista
The identification of a novel natural activator of p300 Histone acetyltranferase provides new insights into the modulation mechanism of this enzyme
CHEMBIOCHEM. Vol. 11. Pag.818-827
ISSN:1439-4227.
DAL PIAZ, Fabrizio; Tosco, Alessandra; Eletto, Daniela; Piccinelli, ANNA LISA; Moltedo, Ornella; Franceschelli, Silvia; Sbardella, Gianluca; Remondelli, Paolo; Rastrelli, Luca; Loredana, Vesci; Claudio, Pisano; DE TOMMASI, Nunziatina
Versione online
Digital Object Identifier (DOI): 10.1002/cbic.200900721
Codice identificativo ISI: WOS:000277299800015
Codice identificativo SCOPUS: 2-s2.0-77950663978
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2009
Articolo in rivista
Endoplasmic reticulum stress reduces the export from the ER and alters the architecture of post-ER compartments.
THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. Vol. 41. Pag.2511-2521
ISSN:1357-2725.
Amodio, Giuseppina; Renna, M; Paladino, S; Venturi, C; Tacchetti, C; Moltedo, Ornella; Franceschelli, Silvia; Mallardo, M; Bonatti, S; Remondelli, Paolo
Digital Object Identifier (DOI): 10.1016/j.biocel.2009.08.006
Codice identificativo ISI: WOS:000272218400023
Codice identificativo SCOPUS: 2-s2.0-70350323730
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2007
Articolo in rivista
Apoptosis inhibition in cancer cells: a novel molecular pathway that involves BAG3 protein
THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. Vol. 39. Pag.1337-1342
ISSN:1357-2725.
Rosati, Alessandra; M., Ammirante; A., Gentilella; Basile, Anna; Festa, Michelina; Pascale, Maria; Marzullo, Liberato; Belisario, MARIA ANTONIETTA; Tosco, Alessandra; Franceschelli, Silvia; Moltedo, Ornella; G., Pagliuca; R., Lerose; Turco, Maria Caterina
Digital Object Identifier (DOI): 10.1016/j.biocel.2007.03.007
Codice identificativo ISI: WOS:000248566700009
Codice identificativo SCOPUS: 2-s2.0-34447104604
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2003
Articolo in rivista
Synthesis and preliminary biological evaluation of a new pyridocarbazole derivative covalently linked to a thymidine nucleoside as a potential targeted antitumoral agent.
CHEMICAL & PHARMACEUTICAL BULLETIN. Vol. 51. Pag.971-974
ISSN:0009-2363.
Saturnino, Carmela; M., Buonerba; G., Boatto; Pascale, Maria; Moltedo, Ornella; L., DE NAPOLI; D., Montesarchio; J. C., Lancelot; DE CAPRARIIS, Paolo
Codice identificativo ISI: 000184514200014
Codice identificativo SCOPUS: 2-s2.0-2142771242
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2003
Articolo in rivista
Endosomal trafficking of the Menkes copper ATPase ATP7A is mediated by vesicles containing the Rab7 and Rab5 GTPase proteins
EXPERIMENTAL CELL RESEARCH. Vol. 291. Pag.377-385
ISSN:0014-4827.
Pascale, M.; Belleudi, F.; Moltedo, O.; Franceschelli, S.; Torrisi, M. R.; Bucci, C.; LA FONTAINE, S.; Mercer, J. F. B.; Leone, A.
Codice identificativo ISI: WOS:000187246300011
Codice identificativo SCOPUS: 2-s2.0-0344441418
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2000
Articolo in rivista
Zinc transport and metallothionein secretion in the intestinal human cell line Caco-2.
THE JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 275. Pag.31819-31825
ISSN:0021-9258.
Moltedo, Ornella; Verde, C.; Capasso, A.; Parisi, E.; Remondelli, Paolo; Bonatti, S.; ALVAREZ HERNANDEZ, X.; Glass, J.; Alvino, C. G.; Leone, A.
Codice identificativo SCOPUS: 2-s2.0-0034644672
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1999
Abstract in Atti di convegno
Rab proteins and trafficking of the Menkes disease protein.
In: Copper Homeostasis: Molecular and Cellular Aspects Pag.34-34
2th International Meeting on Copper Homeostasis and its Disorders: Molecular and Cellular Aspects
Pascale, Maria; Marzullo, Liberato; C., Bucci; C., Mercer; J. F. B., Mercer; Moltedo, Ornella; I., Coppola; Leone, Arturo
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1999
Contributo in volume (Capitolo o Saggio)
“Metal regulation of metallothionein gene expression in mammals” in: Copper transport and its disorder: molecular and cellular aspects (A.Leone and J.F. Mercer Eds.).
In A.LEONE AND J.F. MERCER EDS. Advances in Experimental Medicine and Biology; Plenum Press publishers, New York, 1999. Pag.223-236
Remondelli, Paolo; Moltedo, Ornella; Pascale, M. C. AND LEONE A.
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1997
Abstract in rivista
Le colture cellulari nello studio del potere antiossidante di polifenoli naturali e sintetici
GIORNALE ITALIANO DI NUTRIZIONE CLINICA E PREVENTIVA. Vol. VI. Pag.49-56
ISSN:1122-2239.
Manna, C.; Cucciolla, V.; Leone, A.; Moltedo, O.; Palumbo, R. and Galletti P.
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1997
Articolo in rivista
The protective effect of the olive oil polyphenol (3,4- dihydroxyphenyl)-ethanol counteracts reactive oxygen metabolite- induced cytotoxicity in CaCo-2 cells.
JOURNAL OF NUTRITION. Vol. 127. Pag.286-292
ISSN:0022-3166.
Manna, C; Galletti, P; Cucciolla, V; Moltedo, Ornella; Leone, Arturo; Zappia, V.
Codice identificativo SCOPUS: 2-s2.0-0031055739
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1997
Articolo in rivista
Regulation Zirf1 and basal SP1 trascription factor MRE-binding activity by transition metals.
FEBS LETTERS. Vol. 416. Pag.254-258
ISSN:0014-5793.
Remondelli, Paolo; Moltedo, Ornella; Leone, Arturo
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