Silvia FRANCESCHELLI | APPLIED BIOLOGY AND BASIC OF PHYSIOLOGY

cod. 0712300002

APPLIED BIOLOGY AND BASIC OF PHYSIOLOGY

	0712300002
	DIPARTIMENTO DI FARMACIA
	EQF6
	PHARMACEUTICALS AND NUTRACEUTICALS FOR ANIMALS
	2023/2024

PERCORSO COMUNE

	OBBLIGATORIO
	YEAR OF COURSE 1
	YEAR OF DIDACTIC SYSTEM 2022
	AUTUMN SEMESTER

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
	BIO/13	9	72	LESSONS	BASIC COMPULSORY SUBJECTS

PROFESSORS

	SILVIA FRANCESCHELLI T Curriculum
	ROSALINDA SORRENTINO Curriculum

	Objectives
	THE COURSE AIMS TO PROVIDE INFORMATION ON THE BASIC MECHANISMS INVOLVED IN THE EXPRESSION, DUPLICATION AND TRANSMISSION OF GENETIC INFORMATION; IN CELL DEVELOPMENT, DIFFERENTIATION, PROLIFERATION; BIOGENESIS OF ORGANELLES AND CELLULAR STRUCTURES, THEIR FUNCTION AND REGULATION; INTERACTION BETWEEN CELLS, BIOLOGICAL BASIS OF EVOLUTION; TO PROVIDE BASIC ELEMENTS OF THE PHYSIOLOGICAL FUNCTIONS OF LIVESTOCK AND COMPANION ANIMALS, IN ORDER TO PROVIDE THE BASIS FOR UNDERSTANDING ANIMAL PHARMACEUTICALS AND NUTRACEUTICALS AT THE END OF THE COURSE THE STUDENT WILL KNOW: 1) ORGANIZATION AND FUNCTION OF THE EUKARYOTIC CELL 2) MOLECULAR BASIS OF THE MAIN CELLULAR FUNCTIONS AND REGULATORY SYSTEMS 3) FUNCTION OF THE DIFFERENT CELLULAR ORGANELLES AND THEIR RELATIONSHIPS 4) KNOW THE PHYSIOLOGY OF THE CARDIOVASCULAR, DIGESTIVE, URINARY, NERVOUS, ENDOCRINE AND IMMUNE SYSTEMS OF FARM AND COMPANION ANIMALS THE STUDENT, APPLYING THE SKILLS ACQUIRED, MUST BE ABLE TO: 1) UNDERSTAND CLASSICAL AND ADVANCED CONCEPTS OF CELL BIOLOGY 2) IDENTIFY THE MOLECULAR AND CELLULAR BASIS OF PATHOLOGIES 3) ADDRESS AND SOLVE PROBLEMS RELATED TO CELL BIOLOGY 4) UNDERSTAND THE FUNCTIONING AND THE INTERACTIONS BETWEEN DIFFERENT ORGANS AND ANIMAL TISSUES

THE COURSE AIMS TO PROVIDE INFORMATION ON THE BASIC MECHANISMS INVOLVED IN THE EXPRESSION, DUPLICATION AND TRANSMISSION OF GENETIC INFORMATION; IN CELL DEVELOPMENT, DIFFERENTIATION, PROLIFERATION; BIOGENESIS OF ORGANELLES AND CELLULAR STRUCTURES, THEIR FUNCTION AND REGULATION; INTERACTION BETWEEN CELLS, BIOLOGICAL BASIS OF EVOLUTION; TO PROVIDE BASIC ELEMENTS OF THE PHYSIOLOGICAL FUNCTIONS OF LIVESTOCK AND COMPANION ANIMALS, IN ORDER TO PROVIDE THE BASIS FOR UNDERSTANDING ANIMAL PHARMACEUTICALS AND NUTRACEUTICALS
AT THE END OF THE COURSE THE STUDENT WILL KNOW:
1) ORGANIZATION AND FUNCTION OF THE EUKARYOTIC CELL
2) MOLECULAR BASIS OF THE MAIN CELLULAR FUNCTIONS AND REGULATORY SYSTEMS
3) FUNCTION OF THE DIFFERENT CELLULAR ORGANELLES AND THEIR RELATIONSHIPS
4) KNOW THE PHYSIOLOGY OF THE CARDIOVASCULAR, DIGESTIVE, URINARY,
NERVOUS, ENDOCRINE AND IMMUNE SYSTEMS OF FARM AND COMPANION
ANIMALS
THE STUDENT, APPLYING THE SKILLS ACQUIRED, MUST BE ABLE TO:
1) UNDERSTAND CLASSICAL AND ADVANCED CONCEPTS OF CELL BIOLOGY
2) IDENTIFY THE MOLECULAR AND CELLULAR BASIS OF PATHOLOGIES
3) ADDRESS AND SOLVE PROBLEMS RELATED TO CELL BIOLOGY
4) UNDERSTAND THE FUNCTIONING AND THE INTERACTIONS BETWEEN DIFFERENT
ORGANS AND ANIMAL TISSUES

	Prerequisites
	BASIC KNOWLEDGE OF GENERAL AND INORGANIC CHEMISTRY, PHYSICS AND MATHEMATICS PROVIDED BY HIGH SCHOOLS.

	Contents
	APPLIED BIOLOGY (48 HR, 6 CFU) CHEMICAL BASIS OF LIFE: THE ORGANIC MOLECULES (6 HR) GENERAL CHARACTERISTICS OF THE CELLS (2 HR) STRUCTURE AND FUNCTION OF THE PLASMA MEMBRANE (4 HR) THE SYSTEMS OF CYTOPLASMIC MEMBRANES: STRUCTURE, FUNCTION AND MEMBRANE TRAFFICKING (4 HR) AEROBIC RESPIRATION AND MITOCHONDRIA (4 HR) CYTOSKELETON AND CELL MOTILITY (4 HR) CELL COMMUNICATION (2 HR) CELL SIGNALING AND SIGNAL TRANSDUCTION (2 HR) DNA, CHROMOSOMES AND GENOMES (2 HR) THE NUCLEUS AND THE CONTROL OF GENE EXPRESSION (4 HR) REPLICATION AND REPAIR OF DNA (2 HR) GENE EXPRESSION: FROM TRANSCRIPTION TO TRANSLATION (6 HR) CELL CICLE AND CELLULAR REPRODUCTION (4 HR) MENDELIAN GENETICS (4 HR) BASICS OF PHYSIOLOGY (24 HR, 3 CFU) INTRODUCTION TO PHYSIOLOGY: HOMEOSTASIS, POSITIVE AND NEGATIVE FEEDBACK (2 HOURS) CELL COMMUNICATION: MEMBRANE POTENTIAL, VOLTAGE-GATED ION CHANNELS, GRADED POTENTIAL, ACTION POTENTIAL (2 HOURS) NERVOUS SYSTEM: NEURON, PROPAGATION OF THE ACTION POTENTIAL ALONG THE AXON, ABSOLUTE AND RELATIVE REFRACTORY PERIOD; NEUROGLIA CELLS; CNS, PNS, AFFERENT (GENERAL AND SPECIFIC SENSITIVITY) AND EFFERENT (SOMATIC AND AUTONOMIC) (4 HOURS) ENDOCRINE SYSTEM: ADENOHYPOPHYSIS, NEUROHYPOPHYSIS, THYROID, PARATHYROIDS, PANCREAS, ADRENAL GLANDS, KIDNEYS, HEART, THYMUS, GONADS AND THEIR HORMONES (4 HOURS) CARDIOVASCULAR SYSTEM: BLOOD, VESSELS, REGULATION OF BLOOD FLOW AND PRESSURE, HEART, CARDIAC CYCLE, CARDIAC CONDUCTION SYSTEM (4 HR) DIGESTIVE SYSTEM: ORAL CAVITY, ESOPHAGUS, STOMACH, SMALL AND LARGE INTESTINE, EXOCRINE PANCREAS, LIVER (2 HOURS) IMMUNE SYSTEM: INNATE AND ADAPTIVE IMMUNITY (2 HOURS) REPRODUCTIVE SYSTEM: MALE (EXTERNAL GENITALIA, RELATED DUCTS AND GLANDS; HORMONAL REGULATION, ERECTION REFLEX, EJACULATION) AND FEMALE (OOGENESIS, FERTILIZATION, LACTATION) (4 HR)

Contents

APPLIED BIOLOGY (48 HR, 6 CFU)
CHEMICAL BASIS OF LIFE: THE ORGANIC MOLECULES (6 HR)
GENERAL CHARACTERISTICS OF THE CELLS (2 HR)
STRUCTURE AND FUNCTION OF THE PLASMA MEMBRANE (4 HR)
THE SYSTEMS OF CYTOPLASMIC MEMBRANES: STRUCTURE, FUNCTION AND MEMBRANE TRAFFICKING (4 HR)
AEROBIC RESPIRATION AND MITOCHONDRIA (4 HR)
CYTOSKELETON AND CELL MOTILITY (4 HR)
CELL COMMUNICATION (2 HR)
CELL SIGNALING AND SIGNAL TRANSDUCTION (2 HR)
DNA, CHROMOSOMES AND GENOMES (2 HR)
THE NUCLEUS AND THE CONTROL OF GENE EXPRESSION (4 HR)
REPLICATION AND REPAIR OF DNA (2 HR)
GENE EXPRESSION: FROM TRANSCRIPTION TO TRANSLATION (6 HR)
CELL CICLE AND CELLULAR REPRODUCTION (4 HR)
MENDELIAN GENETICS (4 HR)

BASICS OF PHYSIOLOGY (24 HR, 3 CFU)
INTRODUCTION TO PHYSIOLOGY: HOMEOSTASIS, POSITIVE AND NEGATIVE FEEDBACK (2 HOURS)
CELL COMMUNICATION: MEMBRANE POTENTIAL, VOLTAGE-GATED ION CHANNELS, GRADED POTENTIAL, ACTION POTENTIAL (2 HOURS)
NERVOUS SYSTEM: NEURON, PROPAGATION OF THE ACTION POTENTIAL ALONG THE AXON, ABSOLUTE AND RELATIVE REFRACTORY PERIOD; NEUROGLIA CELLS; CNS, PNS, AFFERENT (GENERAL AND SPECIFIC SENSITIVITY) AND EFFERENT (SOMATIC AND AUTONOMIC) (4 HOURS)
ENDOCRINE SYSTEM: ADENOHYPOPHYSIS, NEUROHYPOPHYSIS, THYROID, PARATHYROIDS, PANCREAS, ADRENAL GLANDS, KIDNEYS, HEART, THYMUS, GONADS AND THEIR HORMONES (4 HOURS)
CARDIOVASCULAR SYSTEM: BLOOD, VESSELS, REGULATION OF BLOOD FLOW AND PRESSURE, HEART, CARDIAC CYCLE, CARDIAC CONDUCTION SYSTEM (4 HR)
DIGESTIVE SYSTEM: ORAL CAVITY, ESOPHAGUS, STOMACH, SMALL AND LARGE INTESTINE, EXOCRINE PANCREAS, LIVER (2 HOURS)
IMMUNE SYSTEM: INNATE AND ADAPTIVE IMMUNITY (2 HOURS)
REPRODUCTIVE SYSTEM: MALE (EXTERNAL GENITALIA, RELATED DUCTS AND GLANDS; HORMONAL REGULATION, ERECTION REFLEX, EJACULATION) AND FEMALE (OOGENESIS, FERTILIZATION, LACTATION) (4 HR)

	Teaching Methods
	THE COURSE OF APPLIED BIOLOGY AND BASICS OF PHYSIOLOGY INCLUDES: LECTURES WITH THE SUPPORT OF MODERN TEACHING SUPPORTS SUCH AS PROJECTIONS BY MEANS OF MULTIMEDIA PRESENTATIONS WITH DEDICATED EDUCATIONAL FILMS;THE ATTENDANCE TO THE LECTURES OF THE COURSE IS MANDATORY. THE TEACHER WILL COMMUNICATE THE MODE OF ATTENDANCE CONTROL ON THE FIRST LECTURE OF THE COURSE. STUDENTS WHO FAIL TO SATISFY THE ATTENDANCE REQUIREMENT, WILL BE REQUIRED TO ATTEND A SERIAL OF INFORMAL TUTORIALS ACCORDING TO THE TEACHER'S INSTRUCTION.

Teaching Methods

THE COURSE OF APPLIED BIOLOGY AND BASICS OF PHYSIOLOGY INCLUDES: LECTURES WITH THE SUPPORT OF MODERN TEACHING SUPPORTS SUCH AS PROJECTIONS BY MEANS OF MULTIMEDIA PRESENTATIONS WITH DEDICATED EDUCATIONAL FILMS;THE ATTENDANCE TO THE LECTURES OF THE COURSE IS MANDATORY. THE TEACHER WILL COMMUNICATE THE MODE OF ATTENDANCE CONTROL ON THE FIRST LECTURE OF THE COURSE. STUDENTS WHO FAIL TO SATISFY THE ATTENDANCE REQUIREMENT, WILL BE REQUIRED TO ATTEND A SERIAL OF INFORMAL TUTORIALS ACCORDING TO THE TEACHER'S INSTRUCTION.

	Verification of learning
	THE EXAMINATION CONSISTS OF A WRITTEN AND AN ORAL TEST, TO BE SUSTAINED IN THE SAME EXAM SESSION. THE RATING IS X/30. TO PASS THE WRITTEN TEST WITH A SCORE OF 18/30 IS MANDATORY TO ACCESS TO THE ORAL TEST, AND REACH THE FINAL GRADE. THE WRITTEN TEST CONSISTS OF THE ADMINISTRATION OF A QUESTIONAIRE WITH BLOCKED MULTIPLE CHOICE QUESTIONS (30 QUESTIONS AND HAS A DURATION NOT EXCEEDING 40 MINUTES) THE SUBJECT TOPICS OF THE WRITTEN TEST IS RELATED TO THE COURSE PROGRAM AND IN PARTICULAR THE TOPICS OF APPLIED BIOLOGY AND ARE AIMED AT VERIFYING THE ABILITY TO UNDERSTAND THE PROBLEMS PROPOSED. IN THE ORAL TEST THE STUDENT WILL BE ASKED TO DISCUSS THE MAIN TOPICS OF THE COURSE, TRYING TO DEMONSTRATE CRITICAL THOUGHT AND AWARENESS OF THE STRUCTURE OF THE FIELD OF STUDY. DURING THE COURSE, THE STUDENT WILL HAVE THE OPPORTUNITY TO CARRY OUT 3 PARTIAL TESTS, (NOT MANDATORY). THE TOPICS COVERED BY THE ONGOING TESTS WILL CONCERN APPLIED BIOLOGY. THE LESSONS DEDICATED TO APPLIED BIOLOGY WILL BE DIVIDED INTO THREE BLOCKS AND EACH IN ITINERE TEST WILL BE CARRIED OUT AT THE END OF EVERY SINGLE BLOCK. THE DATES OF PERFORMANCE OF THE ABOVE TESTS WILL BE AGREED WITH THE ATTENDING STUDENTS AND COMMUNICATED TO THE STUDENTS WELL IN ADVANCE OF THE DATE OF PERFORMANCE.THE PASSING OF THE PARTIAL TESTS MAY EXEMPT FROM THE PERFORMANCE OF THE WRITTEN TEST. THE EXEMPTION APPLIES EXCLUSIVELY TO THE EXAMINATION SESSION IMMEDIATELY AFTER THE TEACHING SESSION. THE FINAL GRADE IS GIVEN BY THE AVERAGE OF THE VOTES OBTAINED FOR EACH UNIT

Verification of learning

THE EXAMINATION CONSISTS OF A WRITTEN AND AN ORAL TEST, TO BE SUSTAINED IN THE SAME EXAM SESSION. THE RATING IS X/30. TO PASS THE WRITTEN TEST WITH A SCORE OF 18/30 IS MANDATORY TO ACCESS TO THE ORAL TEST, AND REACH THE FINAL GRADE.
THE WRITTEN TEST CONSISTS OF THE ADMINISTRATION OF A QUESTIONAIRE WITH BLOCKED MULTIPLE CHOICE QUESTIONS (30 QUESTIONS AND HAS A DURATION NOT EXCEEDING 40 MINUTES)
THE SUBJECT TOPICS OF THE WRITTEN TEST IS RELATED TO THE COURSE PROGRAM AND IN PARTICULAR THE TOPICS OF APPLIED BIOLOGY AND ARE AIMED AT VERIFYING THE ABILITY TO UNDERSTAND THE PROBLEMS PROPOSED.
IN THE ORAL TEST THE STUDENT WILL BE ASKED TO DISCUSS THE MAIN TOPICS OF THE COURSE, TRYING TO DEMONSTRATE CRITICAL THOUGHT AND AWARENESS OF THE STRUCTURE OF THE FIELD OF STUDY.

DURING THE COURSE, THE STUDENT WILL HAVE THE OPPORTUNITY TO CARRY OUT 3 PARTIAL TESTS, (NOT MANDATORY). THE TOPICS COVERED BY THE ONGOING TESTS WILL CONCERN APPLIED BIOLOGY. THE LESSONS DEDICATED TO APPLIED BIOLOGY WILL BE DIVIDED INTO THREE BLOCKS AND EACH IN ITINERE TEST WILL BE CARRIED OUT AT THE END OF EVERY SINGLE BLOCK. THE DATES OF PERFORMANCE OF THE ABOVE TESTS WILL BE AGREED WITH THE ATTENDING STUDENTS AND COMMUNICATED TO THE STUDENTS WELL IN ADVANCE OF THE DATE OF PERFORMANCE.THE PASSING OF THE PARTIAL TESTS MAY EXEMPT FROM THE PERFORMANCE OF THE WRITTEN TEST. THE EXEMPTION APPLIES EXCLUSIVELY TO THE EXAMINATION SESSION IMMEDIATELY AFTER THE TEACHING SESSION.

THE FINAL GRADE IS GIVEN BY THE AVERAGE OF THE VOTES OBTAINED FOR EACH UNIT

	Texts
	APPLIED BIOLOGY: GINELLI E., MALCOVATI M. MOLECOLE, CELLULE E ORGANISMI- EDISES ALBERTS B. ET AL - ESSENTIAL CELL BIOLOGY 5TH EDITION BECKER “WORLD OF THE CELL”, PEARSON KARP G.- CELL AND MOLECULAR BIOLOGY: CONCEPT AND EXPERIMENTS BASICS OF PHYSIOLOGY: SHERWOOD L, KLANDORF H, YANCEY P. PHYSIOLOGY OF ANIMALS-FROM GENES TO ORGANISMS. ZANICHELLI SJAASTAD ØV, SAND O, HOVE K. PHYSIOLOGY OF DOMESTIC ANIMALS. CASA EDITRICE AMBROSIANA RETRIEVED FROM MASON KA, LOSOS JB, SINGER SR. BIOLOGY. STRUCTURE AND FUNCTION IN ANIMALS. PICCIN

Texts

APPLIED BIOLOGY:
GINELLI E., MALCOVATI M. MOLECOLE, CELLULE E ORGANISMI- EDISES
ALBERTS B. ET AL - ESSENTIAL CELL BIOLOGY 5TH EDITION
BECKER “WORLD OF THE CELL”, PEARSON
KARP G.- CELL AND MOLECULAR BIOLOGY: CONCEPT AND EXPERIMENTS

BASICS OF PHYSIOLOGY:
SHERWOOD L, KLANDORF H, YANCEY P. PHYSIOLOGY OF ANIMALS-FROM GENES TO ORGANISMS. ZANICHELLI
SJAASTAD ØV, SAND O, HOVE K. PHYSIOLOGY OF DOMESTIC ANIMALS. CASA EDITRICE AMBROSIANA
RETRIEVED FROM MASON KA, LOSOS JB, SINGER SR. BIOLOGY. STRUCTURE AND FUNCTION IN ANIMALS. PICCIN

	More Information
	APPLIED BIOLOGY AND BASICS OF PHYSIOLOGY: SILVIA FRANCESCHELLI AND MICHELA TERLIZZI LECTURES IN ITALIAN LOCATION DEPT. OF PHARMACY

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Silvia FRANCESCHELLI | APPLIED BIOLOGY AND BASIC OF PHYSIOLOGY