PHARMACOLOGY AND PHARMACOTHERAPY

Ada POPOLO PHARMACOLOGY AND PHARMACOTHERAPY

0760100021
DIPARTIMENTO DI FARMACIA
CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 5 ANNI
PHARMACY
2014/2015

OBBLIGATORIO
YEAR OF COURSE 4
YEAR OF DIDACTIC SYSTEM 2010
PRIMO SEMESTRE
CFUHOURSACTIVITY
1080LESSONS


Objectives
THE COURSE AIMS TO PROVIDE STUDENTS WITH:
• KNOWLEDGE AND UNDERSTANDING
THE BASIC CONCEPTS OF KNOWLEDGE IN THE FIELD OF PHARMACOLOGY AND BIO-ACTIVE PRINCIPLES USED IN THERAPIES TO TREAT DISEASES AND DISEASE STATES AND DRUG-INDUCED ADVERSE EVENTS. THE COURSE ALSO INCLUDES SPECIFIC TOPICS IN THE FIELD OF PHARMACOLOGY THAT ALLOW ACCURATE STUDY OR ANALYSIS BASED ON A SYSTEMATIC UNDERSTANDING AND CRITICAL AWARENESS OF KNOWLEDGE DRUG.
• APPLYING KNOWLEDGE AND UNDERSTANDING
THE ABILITY TO APPLY THE KNOWLEDGE ACQUIRED IN PHARMACOLOGY AND TOXICOLOGY, IN PROBLEMS THAT MAY OCCUR THERAPIES SUCH AS THE ASSESSMENT OF ADVERSE EVENTS FOR THERAPY SUSTAINABILITY, TO IDENTIFY PROBLEM SOLVING TAKING INTO ACCOUNT THE INTERDISCIPLINARITY THAT CHARACTERIZES THE PHARMACOLOGY.
• MAKING JUDGMENTS
MAKING JUDGMENTS AND INTEGRATING KNOWLEDGE TO MANAGE THE COMPLEXITY OF THERAPY FOR INNOVATING PHARMACOLOGY. WITH REGARD TO THE PHARMACIST ROLE AS INTERFACE BETWEEN THE PHYSICIAN AND THE PATIENT, TO MAKE JUDGMENTS ON THE BASIS OF INCOMPLETE OR LIMITED INFORMATION, BUT THAT INCLUDE REFLECTING ON SOCIAL AND ETHICAL RESPONSIBILITIES LINKED TO THE APPLICATION OF THEIR KNOWLEDGE AND JUDGMENTS;
• COMMUNICATION SKILLS
THE ABILITY TO COMMUNICATE IN A CLEAR AND UNAMBIGUOUS CONCLUSIONS OF THEIR KNOWLEDGE AND JUDGMENT TO A SPECIALIST (HEALTH WORKERS) AND NON-SPECIALISTS (PATIENTS) OF ANY GRADE AND LEVEL OF EDUCATION.
• LEARNING SKILLS
LEARNING SKILLS IN A SELF-DIRECTED OR AUTONOMY THAT MAY HELP FOR CONTINUOUS UPDATING, A NECESSARY CONDITION FOR THE PERFORMANCE OF THE FUNCTIONS OF A PHARMACIST, THROUGH THE USE OF TEXTS, SCIENTIFIC PUBLICATIONS IN THE FIELD, THE MAIN DATABASES OF REGULATORY AGENCIES (EMA, FDA, AIFA, ETC.).
Prerequisites
FOR UNDERSTANDING OF THIS COURSE, IT IS IMPORTANT THE ACQUISITION OF THE FOLLOWING DISCIPLINES: ANATOMY, BIOCHEMISTRY, PHYSIOLOGY AND GENERAL PATHOLOGY
Contents
GENERAL PHARMACOLOGY: DEFINITIONS. DOSES. DOSE/EFFECT RESPONSE AND ITS ANALYSIS. DRUG/RECEPTOR INTERACTION AND ITS ANALYSIS. THERAPEUTIC INDEX. PLACEBO. HOMEOPATHY. PHASES OF THE STUDY OF NEW DRUGS. CONTROL AND DRUG INFORMATION.

PHARMACOKINETICS: ROUTES OF ADMINISTRATION. ABSORPTION. DISTRIBUTION. METABOLISM. EXCRETION. PHARMACOKINETIC INTERACTIONS.

PHARMACODYNAMICS: INTERACTION DRUG/RECEPTOR. AGONIST. PD2. ANTAGONIST. PA2. PARTIAL AGONIST/ANTAGONIST. TRANSDUCTION OF DRUG/RECEPTOR INTERACTION. IONOTROPIC RECEPTORS. METABOTROPIC RECEPTORS. VOLTAGE-GATED ION CHANNELS. INTRACELLULAR RECEPTORS. RECEPTORS FOR GROWTH FACTORS. INTRACELLULAR TRANSDUCTION MECHANISMS. CALCIUM HOMEOSTASIS. PHARMACODYNAMIC INTERACTIONS.

PHARMACOTHERAPY: NOMENCLATURE AND CLASSIFICATION OF DRUGS. PERIPHERAL NERVOUS SYSTEM AND ITS MEDIATORS. PARASYMPATHOMIMETICS. PARASYMPATHOLYTICS. SYMPATHOMIMETICS. SYMPATHOLYTICS. INHIBITORS OF ADRENERGIC NEURON. NEUROMUSCULAR BLOCKERS. DRUGS FOR GANGLIA. LOCAL ANESTHETICS. CENTRAL NERVOUS SYSTEM AND ITS MEDIATORS. GENERAL ANESTHETICS. SEDATIVES AND HYPNOTICS. CENTRAL NERVOUS SYSTEM STIMULANTS. ANXIOLYTICS. ANTI-PSYCHOTICS. ANTI-DEPRESSANTS. ANTI-EPILEPTIC. TREATMENT OF PARKINSON DISEASE. TREATMENT OF ALZHEIMER DISEASE. MUSCLE RELAXANTS. OPIOID ANALGESICS. AUTACOIDS: HISTAMINE, SEROTONIN, EICOSANOIDS, PAF, NITROGEN OXIDE. VASOACTIVE PEPTIDES: RENIN/ANGIOTENSIN SYSTEM, BRADYKININ, ENDOTHELIN. ANTI-HYPERTENSIVES. ANTI-ANGINAL. ANTI-ARRHYTHMICS. INOTROPES POSITIVE. TREATMENT OF HYPERLIPIDEMIA. TREATMENT OF DIABETES. DIURETICS. ANTI-INFLAMMATORY. ANTI-GOUT. ANTI-ASTHMATICS. IMMUNOMODULETORS. ANTI-ACIDS AND ANTI-ULCER. ANTI-COAGULANTS. ANTI-THROMBOTIC. THROMBOLYSIS. DRUGS OF UTERINE MOTILITY. SEX HORMONES AND THEIR PHARMACOLOGICAL REGULATION.
Teaching Methods
CLASS
Verification of learning
- IN ITINERE TESTS FOR SELF-ASSESSMENT
- ORAL TEST
Texts
- GOODMAN & GILMAN, LE BASI FARMACOLOGICHE DELLA TERAPIA. MCGRAW-HILL (11A EDIZIONE).
- CLEMENTI & FUMAGALLI, FARMACOLOGIA GENERALE E - MOLECOLARE. UTET, TORINO (3A EDIZIONE).
- ANNUNZIATO & DI RENZO, TRATTATO DI FARMACOLOGIA. IDELSON-GNOCCHI
- B.G. KATZUNG, FARMACOLOGIA GENERALE E CLINICA. PICCIN (6A EDIZIONE).
More Information
YEAR OF COURSE: IV
SEMESTER: I
UFC: 10
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