HETEROCYCLIC CHEMISTRY

Stefania TERRACCIANO HETEROCYCLIC CHEMISTRY

0760100035
DIPARTIMENTO DI FARMACIA
EQF7
PHARMACY
2022/2023

YEAR OF DIDACTIC SYSTEM 2016
AUTUMN SEMESTER
CFUHOURSACTIVITY
540LESSONS
Objectives
THE COURSE IS AIMED AT THE ACQUISITION OF KNOWLEDGE AND UNDERSTANDING OF CLASSIFICATION, NOMENCLATURE, STRUCTURE, PROPERTIES, REACTIVITY AND SYNTHESIS OF THE MAIN HETEROCYCLIC COMPOUNDS.
THE STUDENT APPLYING THE ACQUIRED SKILLS SHOULD BE ABLE TO DISCUSS THE STRUCTURE AND PROPERTIES OF HETEROCYCLES AND ANALYZE THE SYNTHETIC METHODS OF THE MOST IMPORTANT HETEROCYCLIC RINGS OF BIOLOGICAL INTEREST.
Prerequisites
IN ORDER TO UNDERSTAND AND KNOW HOW TO APPLY MOST OF THE TOPICS COVERED IN TEACHING, THE STUDENT MUST PASS THE EXAMINATION OF ORGANIC CHEMISTRY
Contents
INTRODUCTION, DEFINITION OF TERMS AND CLASSIFICATION OF THE MAJOR CLASSES OF HETEROCYCLIC COMPOUNDS. (2H)
SYSTEMATIC NOMENCLATURE OF HETEROCYCLIC COMPOUNDS. (4H)
SYNTHESIS AND MODIFICATION OF HEREOCYCLIC RINGS, EXAMPLES OF COMMONLY USED STRATEGIES FOR HETEROCYCLE SYNTHESIS. (GENERAL METHODS USED FOR THE SYNTHESIS OF HETEROCYCLES. (3H)
STRUCTURE, GENERAL PROPERTIES AND CHEMICAL REACTIVITY OF HETEROCYCLIC COMPOUNDS. (3H)
THE HETEROCYCLES WILL BE CONSIDERED ARE:
THREE-MEMBERED HETEROCYCLES: STRUCTURE, PREPARATION AND REACTIONS. (4H)
FOUR-MEMBERED HETEROCYCLES: STRUCTURE, PREPARATION AND REACTIONS. (4H)
FIVE-MEMBERED HETEROCYCLES AND THEIR BENZOCONDENSED ANALOGS: STRUCTURE, PREPARATION AND REACTIONS. (4H)
SIX-MEMBERED HETEROCYCLE THEIR BENZOCONDENSED ANALOGS: STRUCTURE, PREPARATION AND REACTIONS. (5H)
DIAZINES AND ITS DERIVATIVES. (2H)
PURINES: STRUCTURE, PREPARATION AND REACTIONS. (2H)
EXAMPLES OF HETEROCYCLIC COMPOUNDS IN NATURE, ORGANIC AND MEDICINAL CHEMISTRY. (3H)
Teaching Methods
THE COURSE INCLUDES 40 HOURS (5 CFU) OF FRONTAL LESSONS.
THE FREQUENCY OF LESSONS IS MANDATORY.
IN ORDER TO BE ABLE TO TAKE THE FINAL EXAM, THE STUDENT MUST HAVE ATTENDED AT LEAST 70% OF THE TEACHING HOURS.
Verification of learning
THE FINAL PREPARATION ASSESSMENT IS CERTIFIED BY AN EVALUATION RANGING FROM 18 TO 30/30 AND LIES IN A WRITTEN AND AN ORAL TEST. THE WRITTEN EXAM (2 HOURS) IS PREPARATORY TO THE ORAL TEST AND CONSISTS IN A TEST CONCERNING THE PROGRAM OF TEACHING. THE WRITING TEST WILL LAST FOR TWO HOURS AND CONSISTS OF NOMENCLATURE EXERCISES, EXERCISES ON REACTIVITY, SYNTHESIS, REACTION MECHANISMS AND CHEMICAL PROPERTIES OF HETEROCYCLIC COMPOUNDS. THE ORAL TEST CONSISTS IN A DISCUSSION (ABOUT 30 MINUTES) ON THE THEORETICAL AND METHODOLOGICAL CONTENTS INDICATED IN THE PROGRAM OF TEACHING AND IS FINALIZED TO ASSESS THE LEVEL OF KNOWLEDGE AND COMPRESSION REACHED BY THE STUDENT, AND TO CHECK THE EXPOSURE CAPACITY, THE CAPACITY TO EXPLAIN AND TO ELABORATE SOLUTIONS INDEPENDENTLY. THE SCORE OF THE ORAL EXAM (FROM 18 TO 30/30 CUM LAUDE)
IT DEPENDS ON THE DEGREE OF DEPTH AND THE STUDENT'S ABILITY TO PRESENT
EFFECTIVELY THE CONTENTS AND CRITICALLY DISCUSS THE TOPICS ILLUSTRATED.
Texts
D. SICA, F. ZOLLO, CHIMICA DEI COMPOSTI ETEROCICLICI FARMACOLOGICAMENTE ATTIVI, PICCIN.
BROGGINI-ZECCHI, CHIMICA DEI COMPOSTI ETEROCICLICI, ZANICHELLI.
JOHN A. JOULE, KEITH MILLS, HETEROCYCLIC CHEMISTRY, WILEY.
NOTES
More Information

THE COURSE IS TAUGHT IN ITALIAN
THE ATTENDANCE IS MANDATORY
LOCATION: DEPARTMENT OF PHARMACY
  BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-08-21]