Maria Chiara MONTI | ORGANIC CHEMISTRY II

cod. 0760200013

ORGANIC CHEMISTRY II

	0760200013
	DIPARTIMENTO DI FARMACIA
	EQF7
	PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY
	2022/2023

PERCORSO COMUNE

	OBBLIGATORIO
	YEAR OF COURSE 2
	YEAR OF DIDACTIC SYSTEM 2020
	SPRING SEMESTER

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
	CHIM/06	9	72	LESSONS	BASIC COMPULSORY SUBJECTS

EXAMS

	Exam	Date	Session
	GIUGNO	30/06/2023 - 10:00	SESSIONE ORDINARIA
	LUGLIO	19/07/2023 - 10:00	SESSIONE ORDINARIA

	Objectives
	THE COURSE AIMS TO PROVIDE THE STUDENT WITH A MORE IN-DEPTH TRAINING IN ORGANIC CHEMISTRY COMPARED TO THE FIRST BASIC COURSE, WITH PARTICULAR REGARD TO THE NOMENCLATURE, CHEMICAL PROPERTIES AND REACTIVITY OF MULTIFUNCTIONAL COMPOUNDS; OF THE MAIN CLASSES OF ORGANIC COMPOUNDS OF BIOLOGICAL RELEVANCE: CARBOHYDRATES, AMINO ACIDS AND PEPTIDES, LIPIDS; OF THE MAIN HETEROCYCLIC SYSTEMS. STUDENTS WILL ALSO ACQUIRE KNOWLEDGE ABOUT HAZARDOUS REACTIONS AND THE FUNDAMENTAL PRINCIPLES OF ORGANIC SYNTHESIS, LEARNING TO DEVELOP SIMPLE SYNTHETIC SEQUENCES OF MULTIFUNCTIONAL ORGANIC COMPOUNDS AND TO APPLY THE LEGENDS OF THE STRUCTURAL CHARACTERISTICS OF THE SYNTHESIS OF MODERN SIGNS. FUNCTIONAL GROUPS.

THE COURSE AIMS TO PROVIDE THE STUDENT WITH A MORE IN-DEPTH TRAINING IN ORGANIC CHEMISTRY COMPARED TO THE FIRST BASIC COURSE, WITH PARTICULAR REGARD TO THE NOMENCLATURE, CHEMICAL PROPERTIES AND REACTIVITY OF MULTIFUNCTIONAL COMPOUNDS; OF THE MAIN CLASSES OF ORGANIC COMPOUNDS OF BIOLOGICAL RELEVANCE: CARBOHYDRATES, AMINO ACIDS AND PEPTIDES, LIPIDS; OF THE MAIN HETEROCYCLIC SYSTEMS. STUDENTS WILL ALSO ACQUIRE KNOWLEDGE ABOUT HAZARDOUS REACTIONS AND THE FUNDAMENTAL PRINCIPLES OF ORGANIC SYNTHESIS, LEARNING TO DEVELOP SIMPLE SYNTHETIC SEQUENCES OF MULTIFUNCTIONAL ORGANIC COMPOUNDS AND TO APPLY THE LEGENDS OF THE STRUCTURAL CHARACTERISTICS OF THE SYNTHESIS OF MODERN SIGNS. FUNCTIONAL GROUPS.

	Prerequisites
	THE ACQUISITION OF THE OBJECTIVES RELATING TO THE FOLLOWING DISCIPLINES IS REQUIRED: PHYSICS, GENERAL AND INORGANIC CHEMISTRY, ORGANIC CHEMISTRY 1. IT IS ALSO REQUIRED GENERAL MATHEMATICS KNOWLEDGE

	Contents
	PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN CLASSES OF DIFUNCTIONAL COMPOUNDS: DIOLS 0.5CFU; HYDROXYCARBONYL COMPOUNDS (HYDROXYALDEHYDES, HYDROXYCETONES AND HYDROXYACIDES) 0.5CFU; ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS 0.5CFU; DICARBONYL COMPOUNDS (DICARBOXYL ACIDS, BETA-KETOESTERS, BETA-DICHETONES) 0.5CFU;. MECHANISMS, PROCEDURES AND APPLICATION POTENTIALS OF THE MAIN CLASSES OF REACTIONS OF THE ANIONS ENOLATE 0.5CFU; AND ENAMINES 0.5CFU; PROPERTIES, REACTIVITY AND SYNTHETIC APPLICATIONS OF BETA-DICARBONYL COMPOUNDS AND, MORE GENERALLY, OF COMPOUNDS WITH ACTIVE METHYLENE GROUPS 0.5CFU; STRUCTURE AND REACTIVITY OF ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS V MECHANISMS AND SYNTHETIC APPLICATIONS OF THE AROMATIC NUCLEOPHILIC SUBSTITUTION REACTIONS 0.5CFU; STRUCTURE, PROPERTIES, METHODS OF SYNTHESIS AND REACTIVITY OF PHENOLS 0.5CFU; STRUCTURES, PROPERTIES AND REACTIVITY OF THE MAIN POLYCYCLIC AROMATIC COMPOUNDS 0.5CFU; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY 0.5CFU; OF ALIPHATIC AND AROMATIC AMINES 0.5CFU; AROMATIC DIAZONIUM SALTS AND THEIR METHOD OF USE IN THE ORGANIC SYNTHESIS,THE MOST COMMONLY USED STRATEGIES IN THE SYNTHESIS OF POLYSUBSTITUTED AROMATIC COMPOUNDS 0.5CFU; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN AROMATIC HETEROCYCLIC SYSTEMS 0.5CFU;. PROPERTY, STEREOCHEMISTRY AND REACTIVITY OF MONOSACCHARIDES 0.5CFU; AND OF THE MAIN DEACCARIDES AND POLYSACCHARIDES 0.5CFU; AMINO ACIDS, PEPTIDES AND PROTEINS 0.5CFU;. LIPIDS. DANGEROUS REACTIONS 0.5CFU;

Contents

PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN CLASSES OF DIFUNCTIONAL COMPOUNDS: DIOLS 0.5CFU; HYDROXYCARBONYL COMPOUNDS (HYDROXYALDEHYDES, HYDROXYCETONES AND HYDROXYACIDES) 0.5CFU; ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS 0.5CFU; DICARBONYL COMPOUNDS (DICARBOXYL ACIDS, BETA-KETOESTERS, BETA-DICHETONES) 0.5CFU;. MECHANISMS, PROCEDURES AND APPLICATION POTENTIALS OF THE MAIN CLASSES OF REACTIONS OF THE ANIONS ENOLATE 0.5CFU; AND ENAMINES 0.5CFU; PROPERTIES, REACTIVITY AND SYNTHETIC APPLICATIONS OF BETA-DICARBONYL COMPOUNDS AND, MORE GENERALLY, OF COMPOUNDS WITH ACTIVE METHYLENE GROUPS 0.5CFU; STRUCTURE AND REACTIVITY OF ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS V MECHANISMS AND SYNTHETIC APPLICATIONS OF THE AROMATIC NUCLEOPHILIC SUBSTITUTION REACTIONS 0.5CFU; STRUCTURE, PROPERTIES, METHODS OF SYNTHESIS AND REACTIVITY OF PHENOLS 0.5CFU; STRUCTURES, PROPERTIES AND REACTIVITY OF THE MAIN POLYCYCLIC AROMATIC COMPOUNDS 0.5CFU; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY 0.5CFU; OF ALIPHATIC AND AROMATIC AMINES 0.5CFU; AROMATIC DIAZONIUM SALTS AND THEIR METHOD OF USE IN THE ORGANIC SYNTHESIS,THE MOST COMMONLY USED STRATEGIES IN THE SYNTHESIS OF POLYSUBSTITUTED AROMATIC COMPOUNDS 0.5CFU; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN AROMATIC HETEROCYCLIC SYSTEMS 0.5CFU;. PROPERTY, STEREOCHEMISTRY AND REACTIVITY OF MONOSACCHARIDES 0.5CFU; AND OF THE MAIN DEACCARIDES AND POLYSACCHARIDES 0.5CFU; AMINO ACIDS, PEPTIDES AND PROTEINS 0.5CFU;. LIPIDS. DANGEROUS REACTIONS 0.5CFU;

	Teaching Methods
	THE TEACHING METHOD IS BASED ON THE FRONT LESSON (72H / 9 CFU) AND MAKES THE CONTRIBUTION OF PROJECTED SLIDES TO GUIDE THE TRAINING PATH AND THE ADOPTION OF TEXTS DEDICATED TO THE EXPLANATION OF THE TOPICS. AS PER TEACHING REGULATIONS, THE ATTENDANCE TO TEACHING MUST BE INTENDED AS COMPULSORY, THE METHODS OF CHECKING THE ATTENDANCE WILL BE COMMUNICATED TO THE STUDENTS BY THE TEACHERS; ANY ABSENCES THAT MAY HARM THE ACQUISITION OF THE INDICATED EDUCATIONAL OBJECTIVES MAY BE FILLED WITH CUSTOMIZED ACTIVITIES PREPARED BY THE TEACHING OWNERS. FACILITIES ARE GRANTED TO WORKING STUDENTS ACCORDING TO THE DIDACTIC REGULATION.

Teaching Methods

THE TEACHING METHOD IS BASED ON THE FRONT LESSON (72H / 9 CFU) AND MAKES THE CONTRIBUTION OF PROJECTED SLIDES TO GUIDE THE TRAINING PATH AND THE ADOPTION OF TEXTS DEDICATED TO THE EXPLANATION OF THE TOPICS. AS PER TEACHING REGULATIONS, THE ATTENDANCE TO TEACHING MUST BE INTENDED AS COMPULSORY, THE METHODS OF CHECKING THE ATTENDANCE WILL BE COMMUNICATED TO THE STUDENTS BY THE TEACHERS; ANY ABSENCES THAT MAY HARM THE ACQUISITION OF THE INDICATED EDUCATIONAL OBJECTIVES MAY BE FILLED WITH CUSTOMIZED ACTIVITIES PREPARED BY THE TEACHING OWNERS. FACILITIES ARE GRANTED TO WORKING STUDENTS ACCORDING TO THE DIDACTIC REGULATION.

	Verification of learning
	THE EXAM IS STRUCTURED IN A WRITTEN TEST AND IN AN ORAL TEST AND INCLUDES AN EVALUATION IN THIRTY-THIRTIES FOR BOTH. PASSING THE WRITTEN TEST WITH A SCORE OF AT LEAST 18/30 IS NECESSARY TO BE ABLE TO TAKE THE ORAL TEST AND OBTAIN THE FINAL MARK. DURING THE SEMESTER, TWO ONGOING TESTS WILL TAKE PLACE IN THE SAME WAY AS THE WRITTEN TASK EXPLAINED BELOW. THE ORIENTATION DATES ARE MID-APRIL AND EARLY JUNE. THE WRITTEN TEST CONSISTS OF THE ADMINISTRATION OF AN OPEN ANSWER QUESTIONNAIRE ON THE DIFFERENT TOPICS COVERED IN THE TEACHING PROGRAM, WHICH MUST BE COMPLETED WITHIN 120 MINUTES. THE WRITTEN TEST IS AIMED AT VERIFYING THE STUDENT'S ABILITY TO CORRECTLY APPLY THE KNOWLEDGE ACQUIRED IN THE COURSE TO A SERIES OF PRACTICAL PROBLEMS. IN GENERAL IN THE WRITTEN TEST THERE WILL BE 3 NOMENCLATURE QUESTIONS, 4-5 QUESTIONS CONCERNING THE PRODUCTS EXPECTED IN THE REACTIONS COVERED BY THE COURSE, 2 QUESTIONS ON ASPECTS RELATING TO TRANSFORMATION OF FUNCTIONAL GROUPS OR SYNTHETIC METHODOLOGIES ASPECTS OF THE COURSE, ONE SUBJECT OF THE COURSE AND AN OPEN ANSWERED QUESTION ON ONE OF THE TOPICS COVERED IN WHICH PARTICULAR APPLICATION ASPECTS MAY ALSO BE REQUIRED. THE ORAL TEST CONSISTS OF AN INTERVIEW OF 30/45 MINUTES THAT BEGINS WITH AN IN-DEPTH ANSWERS IN THE WRITTEN TEST (IF ANY) AND CONTINUES WITH TWO / THREE QUESTIONS AND RELATED DISCUSSION ON TOPICS DEVELOPED IN THE COURSE PROGRAM "AND DESCRIPTION CONTENTS OF THE COURSE ". THE COMBINATION OF THE TWO TESTS ALLOWS TO VERIFY THE LEVEL OF LEARNING KNOWLEDGE, THE CORRECT TERMINOLOGY, THE ABILITY TO ANALYSIS, WHICH SHOULD CONSTITUTE THE KNOWLEDGE ACQUIRED. THE EVALUATION TAKES INTO ACCOUNT TOTALLY OF: LEVEL OF KNOWLEDGE ACQUIRED; CAPACITY OF SYNTHESIS AND EXPOSURE; LANGUAGE APPROPRIATION; ABILITY TO ANALYSIS OF THE PROBLEMS AND TO APPLY THE ACQUIRED KNOWLEDGE. THE VERIFICATION METHODS ARE CONSIDERED ADEQUATE IN RELATION TO THE OBJECTIVES OF THE TEACHING, AND ALSO TO THE EXPECTED KNOWLEDGE AND SKILLS. THE FINAL SCORE CONSISTS OF THE WEIGHTED AVERAGE OF THE SCORES OF THE TWO TESTS, WITH GREATER INCIDENCE OF THE ORAL EXAM MARK AND WITH PARTICULAR REGARD TO EXPOSURE SKILLS, ANALYSIS OF THE PROBLEMS AND APPLICATION OF THE KNOWLEDGE ACQUIRED BY THE STUDENT

Verification of learning

THE EXAM IS STRUCTURED IN A WRITTEN TEST AND IN AN ORAL TEST AND INCLUDES AN EVALUATION IN THIRTY-THIRTIES FOR BOTH. PASSING THE WRITTEN TEST WITH A SCORE OF AT LEAST 18/30 IS NECESSARY TO BE ABLE TO TAKE THE ORAL TEST AND OBTAIN THE FINAL MARK.
DURING THE SEMESTER, TWO ONGOING TESTS WILL TAKE PLACE IN THE SAME WAY AS THE WRITTEN TASK EXPLAINED BELOW. THE ORIENTATION DATES ARE MID-APRIL AND EARLY JUNE.
THE WRITTEN TEST CONSISTS OF THE ADMINISTRATION OF AN OPEN ANSWER QUESTIONNAIRE ON THE DIFFERENT TOPICS COVERED IN THE TEACHING PROGRAM, WHICH MUST BE COMPLETED WITHIN 120 MINUTES. THE WRITTEN TEST IS AIMED AT VERIFYING THE STUDENT'S ABILITY TO CORRECTLY APPLY THE KNOWLEDGE ACQUIRED IN THE COURSE TO A SERIES OF PRACTICAL PROBLEMS.
IN GENERAL IN THE WRITTEN TEST THERE WILL BE 3 NOMENCLATURE QUESTIONS, 4-5 QUESTIONS CONCERNING THE PRODUCTS EXPECTED IN THE REACTIONS COVERED BY THE COURSE, 2 QUESTIONS ON ASPECTS RELATING TO TRANSFORMATION OF FUNCTIONAL GROUPS OR SYNTHETIC METHODOLOGIES ASPECTS OF THE COURSE, ONE SUBJECT OF THE COURSE AND AN OPEN ANSWERED QUESTION ON ONE OF THE TOPICS COVERED IN WHICH PARTICULAR APPLICATION ASPECTS MAY ALSO BE REQUIRED.
THE ORAL TEST CONSISTS OF AN INTERVIEW OF 30/45 MINUTES THAT BEGINS WITH AN IN-DEPTH ANSWERS IN THE WRITTEN TEST (IF ANY) AND CONTINUES WITH TWO / THREE QUESTIONS AND RELATED DISCUSSION ON TOPICS DEVELOPED IN THE COURSE PROGRAM "AND DESCRIPTION CONTENTS OF THE COURSE ".
THE COMBINATION OF THE TWO TESTS ALLOWS TO VERIFY THE LEVEL OF LEARNING KNOWLEDGE, THE CORRECT TERMINOLOGY, THE ABILITY TO ANALYSIS, WHICH SHOULD CONSTITUTE THE KNOWLEDGE ACQUIRED. THE EVALUATION TAKES INTO ACCOUNT TOTALLY OF: LEVEL OF KNOWLEDGE ACQUIRED; CAPACITY OF SYNTHESIS AND EXPOSURE; LANGUAGE APPROPRIATION; ABILITY TO ANALYSIS OF THE PROBLEMS AND TO APPLY THE ACQUIRED KNOWLEDGE. THE VERIFICATION METHODS ARE CONSIDERED ADEQUATE IN RELATION TO THE OBJECTIVES OF THE TEACHING, AND ALSO TO THE EXPECTED KNOWLEDGE AND SKILLS. THE FINAL SCORE CONSISTS OF THE WEIGHTED AVERAGE OF THE SCORES OF THE TWO TESTS, WITH GREATER INCIDENCE OF THE ORAL EXAM MARK AND WITH PARTICULAR REGARD TO EXPOSURE SKILLS, ANALYSIS OF THE PROBLEMS AND APPLICATION OF THE KNOWLEDGE ACQUIRED BY THE STUDENT

	Texts
	A LIST OF MODERN TEXTS, WIDELY USED IN ITALIAN AND FOREIGN UNIVERSITIES IS SHOWN. HOWEVER, OTHER TEXTS ARE AVAILABLE THAT CAN PROVIDE THE NECESSARY ELEMENTS FOR STUDYING THE TOPICS DESCRIBED IN THE COURSE CONTENT. WE RECOMMEND THE USE OF TEXTS PUBLISHED IN THE LAST YEARS. B. BOTTA, ORGANIC CHEMISTRY, ED. EDI-ERMES, MILAN; P. Y. BRUICE, ORGANIC CHEMISTRY, ED. EDISES, NAPLES; J. G. SMITH, ORGANIC CHEMISTRY, ED. MCGRAW-HILL, MILAN; J. MCMURRY, ORGANIC CHEMISTRY, ED. PICCIN, PADUA

Texts

A LIST OF MODERN TEXTS, WIDELY USED IN ITALIAN AND FOREIGN UNIVERSITIES IS SHOWN. HOWEVER, OTHER TEXTS ARE AVAILABLE THAT CAN PROVIDE THE NECESSARY ELEMENTS FOR STUDYING THE TOPICS DESCRIBED IN THE COURSE CONTENT. WE RECOMMEND THE USE OF TEXTS PUBLISHED IN THE LAST YEARS.
B. BOTTA, ORGANIC CHEMISTRY, ED. EDI-ERMES, MILAN;
P. Y. BRUICE, ORGANIC CHEMISTRY, ED. EDISES, NAPLES;
J. G. SMITH, ORGANIC CHEMISTRY, ED. MCGRAW-HILL, MILAN;
J. MCMURRY, ORGANIC CHEMISTRY, ED. PICCIN, PADUA

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Maria Chiara MONTI | ORGANIC CHEMISTRY II

ORGANIC CHEMISTRY II

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Maria Chiara MONTI | ORGANIC CHEMISTRY II