PHARMACOLOGICAL ASSAYS AND PRECLINICAL TESTING

Rosalinda SORRENTINO PHARMACOLOGICAL ASSAYS AND PRECLINICAL TESTING

0760200040
DIPARTIMENTO DI FARMACIA
EQF7
PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY
2018/2019

YEAR OF DIDACTIC SYSTEM 2010
PRIMO SEMESTRE
CFUHOURSACTIVITY
540LESSONS
Objectives
THE COURSE AIMS TO PROVIDE THE BASICS TO DEVELOP A DRUG TRIAL , THROUGH THE KNOWLEDGE OF THE MOST COMMONLY USED IN ANIMAL TESTING METHODS AS WELL AS THE FUNDAMENTALS OF STATISTICS APPLIED TO BIOLOGY , REFERRING ALSO TO THE CURRENT LAWS GOVERNING ANIMAL TESTING .
THE STUDENT AT THE END OF THE COURSE WILL DEMONSTRATE THAT IT CAN MANAGE: 1) DRUG TESTING METHODS IN VITRO AND IN VIVO ; 2 ) SUPPLY , HOUSING AND HANDLING OF LABORATORY ANIMALS ; 3 ) TYPE OF ANIMALS TO BE USED ; 4 ) REGULATION IN HOUSING AND THE USE OF ANIMALS IN EXPERIMENTS ; 5 ) ANALYSIS OF THE EXPERIMENTAL DATA BY THE USE OF STATISTICAL TESTS .
Prerequisites
PHARMACOLOGY AND THERAPY CLASS AND EXAMINATION IS COMPULSORY BEFORE ATTENSDING THIS CLASS. IT IS SUGGESTED TO ATTEND THE CLASSES: ANATOMY, PHYSIOLOGY AND PATHOLOGY.
Contents
THIS CLASS AIMS TO GIVE THE STUDENT THE KNWOLEDGE TO TEST IN VIVO AND IN VITRO THE FOLLOWING:
1. ANTIHYPERTYENSIVE DRUGS
2. ANTICOAGULANT DRUGS
3. HYPOGLICEMIC DRUGS
4. ANTIINFLAMMATORY DRUGS
ANTIASTHMATIC, ANTI-COPD AND ANTIFIBROTIC DRUGS
5. ANALGESIC DRUGS
6. GI DRUGS
7. IMMUNTHERAPEUTICS
Teaching Methods
THE CLASS COMPRISES 30 HOURS OF THEORETICAL APPROACH AND 10 HOURS IN A LABORATORY TO LEARN BASIC IN VITRO PROCEDURES.
Verification of learning
THE EVALUATION OF THE STUDENT RELIES UPON AN ORAL DISCUSSION ON THE SUBJECT APPROACHED DURING THE CLASS.
Texts
1. DRUG DISCOVERY AND EVALUATION-PHARMACOLOGICAL ASSAYS, HANS G. VOGEL, ISBN 9783540423966, SPRINGER.
2. QUALSIASI TESTO UNIVERSITARIO DI SAGGI FARMACOLOGICI E SPERIMENTAZIOEN PRE-CLINICA.
3. FONDAMENTI DI STATISTICA PER LE DISCIPLINE BIOMEDICHE, MM. TRIOLA, M. TRIOLA. ISBN9788891902580B, PEARSON
OPPURE
3'. ANALISI STATISTICA DEI DATI BIOLOGICI, MC WITHLOCK, D. SCHLUTER, ISBN 9788808062970, ZANICHELLI.

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