Rosalinda SORRENTINO | PHARMACOLOGY AND PHARMACOTHERAPY
Rosalinda SORRENTINO PHARMACOLOGY AND PHARMACOTHERAPY
cod. 0760400020
PHARMACOLOGY AND PHARMACOTHERAPY
| 0760400020 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY | |
| 2024/2025 |
| OBBLIGATORIO | |
| YEAR OF COURSE 4 | |
| YEAR OF DIDACTIC SYSTEM 2023 | |
| AUTUMN SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| BIO/14 | 12 | 96 | LESSONS |
| Objectives | |
|---|---|
| ACQUISITION OF KNOWLEDGE REGARDING PHARMACODYNAMIC, PHARMACOKINETIC AND MOLECULAR MECHANISM/S OF ACTION AND SIDE EFFECTS OF DRUGS IS AT THE BASIS OF THIS COURSE. KNOWLEDGE AND UNDERSTANDING STUDENTS WILL ACQUIRE KNOWLEDGE ON: -PRINCIPLES OF PHARMACODYNAMIC AND PHARMACOKINETIC -MECHANISM/S OF ACTION OF DRUGS -MECHANISM/S THAT LEAD TO SIDE EFFECTS -INTERACTION AMONG DRUGS -USE OF DRUGS IN A PERSONALIZED MANNER APPLYING KNOWLEDGE AND UNDERSTANDING STUDENTS WILL BE ABLE TO: -DEFINE THE PHARMACOLOGICAL ACTIVITY OF DIFFERENTIAL CLASSES OF DRUGS, INCLUDING EFFECTIVENESS, SECURITY AND ADHESION TO THE THERAPY -DEFINE THE MOST APPROPRIATE CLASS OF DRUG TO BE USED ACCORDING TO THE PATHOLOGY -DEFINE DRUG INTERACTIONS MAKING JUDGEMENT: STUDENTS WILL: -EVALUATE MOLECULAR AND CELLULAR MECHANISM/S AT THE BASE OF DRUG ACTIVITY -DISTINGUISH PHARMACOLOGICAL FROM TOXICOLOGICAL EFFECTS OF DRUGS -EVALUATE THE EFFICACY, EFFECTIVENESS AND SECURITY OF DRUGS COMMUNICATION SKILLS: STUDENTS WILL BE ABLE TO ELABORATE A SCIENTIFIC COMMUNICATION REGARDING THE THERAPEUTIC AND TOXICOLOGICAL ACTIVITIES OF DRUGS, USING AN APPROPRIATE LANGUAGE STUDENTS WILL BE ABLE TO APPROACH ANY EXPERIMENTAL QUESTION IN THE PHARMACOLOGICAL FIELD. |
| Prerequisites | |
|---|---|
| THE STUDENT SHOULD HAVE ACQUIRED KNOWLEDGE OF ANATOMY AND PHYSIOLOGY, BIOCHEMISTRY AND PATHOLOGY. |
| Contents | |
|---|---|
| GENERAL PHARMACOLOGY: DEFINITION/S. DOSES. DOSE/EFFECT RESPONSE AND ITS ANALYSIS. DRUG/RECEPTOR INTERACTION AND ITS ANALYSIS. THERAPEUTIC INDEX. CLINICAL PHASES FOR THE STUDY OF NEW DRUGS. CONTROL AND DRUG INFORMATION. PHARMACOKINETICS (12 HOURS): ROUTES OF ADMINISTRATION. ABSORPTION. DISTRIBUTION. METABOLISM. EXCRETION. PHARMACOKINETIC INTERACTIONS. PHARMACODYNAMICS (12 HOURS): INTERACTION DRUG/RECEPTOR. AGONIST. PD2. ANTAGONIST. PA2. PARTIAL AGONIST/ANTAGONIST. TRANSDUCTION OF DRUG/RECEPTOR INTERACTION. IONOTROPIC RECEPTORS. METABOTROPIC RECEPTORS. VOLTAGE-GATED ION CHANNELS. INTRACELLULAR RECEPTORS. RECEPTORS FOR GROWTH FACTORS. INTRACELLULAR TRANSDUCTION MECHANISMS. CALCIUM HOMEOSTASIS. PHARMACODYNAMIC INTERACTIONS. PHARMACOTHERAPY: NOMENCLATURE AND CLASSIFICATION OF DRUGS. 1. PERIPHERAL NERVOUS SYSTEM AND ITS MEDIATORS (12 HOURS). PARASYMPATHOMIMETICS. PARASYMPATHOLYTICS. SYMPATHOMIMETICS. SYMPATHOLYTICS. INHIBITORS OF ADRENERGIC NEURON. NEUROMUSCULAR BLOCKERS. DRUGS FOR GANGLIA. LOCAL ANESTHETICS. 2. CENTRAL NERVOUS SYSTEM AND ITS MEDIATORS (14 HOURS). GENERAL ANESTHETICS. SEDATIVES AND HYPNOTICS. CENTRAL NERVOUS SYSTEM STIMULANTS. ANXIOLYTICS. ANTI-PSYCHOTICS. ANTI-DEPRESSANTS. ANTI-EPILEPTIC. TREATMENT OF PARKINSON DISEASE. TREATMENT OF ALZHEIMER DISEASE. MUSCLE RELAXANTS. OPIOID ANALGESICS. 3. CARDIOVASCULAR SYSTEM (10 HOURS) VASOACTIVE PEPTIDES: RENIN/ANGIOTENSIN SYSTEM, BRADYKININ, ENDOTHELIN. ANTI-HYPERTENSIVES. ANTI-ANGINAL. ANTI-ARRHYTHMICS. INOTROPES POSITIVE. DIURETICS. 4. TREATMENT OF DIABETES (2 HOURS). 5. AUTACOIDS (2 HOURS): HISTAMINE, SEROTONIN, EICOSANOIDS, PAF, NITROGEN OXIDE 6. ANTI-INFLAMMATORY AGENTS (4 HOURS). 7. ANTI-GOUT (2 HOURS). 8. ANTI-ASTHMATICS, COPD AND PULMONARY FIBROSIS MODULATORS (2 HOURS) 9. IMMUNOMODULATORS (8 HOURS). 10. ANTI-ACIDS AND ANTI-ULCER (2 HOURS). 11. ANTI-COAGULANTS. ANTI-THROMBOTIC. THROMBOLYSIS. ANTI-HEMORRHAGICS. (2 HOURS) 12. DRUGS OF UTERINE MOTILITY. SEX HORMONES AND THEIR PHARMACOLOGICAL REGULATION. (2 HOURS) 13. ANTIEMETIC AGENT. THERAPY FOR ANEMIA. VITAMINS. (2 ORE) 14. TREATMENT OF HYPERLIPIDEMIA. (2 HOURS) 15. GENIC THERAPY. (6 HOURS) |
| Teaching Methods | |
|---|---|
| THE COURSE INCLUDES 96 HOURS OF FRONTAL ASSISTED TEACHING (12 CFU). ATTENDANCE IS MANDATORY. TO TAKE THE FINAL EXAM, THE STUDENT MUST HAVE ATTENDED AT LEAST 70% OF THE TEACHING HOURS. THE PRESENCE IS VERIFIED ELECTRONICALLY. |
| Verification of learning | |
|---|---|
| THE ACQUIRED KNOWLEDGE WILL BE VERIFIED BY AN ORAL EXAM CERTIFIED ACCORDING TO THE EVALUATION OF 30 OUT OF 30. THE EXAM IS AN ORAL TEST WHICH CONSISTS OF AN INTERVIEW WITH QUESTIONS AND DISCUSSION ON THE CONTENTS OF THE TEACHING CLASS. THE ORAL EXAM AIMS TO VERIFY THE ACQUIRED KNOWLEDGE, ABILITY OF CONNECTIONS AMONG THE SUBJECTS AND THE USE OF AN APPROPRIATE TERMINOLOGY. |
| Texts | |
|---|---|
| - GOODMAN & GILMAN, LE BASI FARMACOLOGICHE DELLA TERAPIA. (12A EDIZIONE). ZANICHELLI - GOODMAN & GILMAN LE BASI FARMACOLOGICHE DELLA TERAPIA -IL MANUALE- II EDIZIONE ZANICHELLI - ANNUNZIATO & DI RENZO, TRATTATO DI FARMACOLOGIA. IDELSON-GNOCCHI |
| More Information | |
|---|---|
| YEAR OF COURSE: IV SEMESTER: I UFC: 12 |
BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-11-18]
