COMPLEMENTS OF MEDICINAL CHEMISTRY

Marina SALA COMPLEMENTS OF MEDICINAL CHEMISTRY

0760100037
DIPARTIMENTO DI FARMACIA
EQF7
PHARMACY
2017/2018

YEAR OF COURSE 5
YEAR OF DIDACTIC SYSTEM 2010
SECONDO SEMESTRE
CFUHOURSACTIVITY
540LESSONS
Objectives
The aim of the course is to make the student aware of the combinatorial chemistry, synthetic protocols in parallel solid and liquid phase and drug design fundamentals.
The student applying the acquired skills must be able to identify and optimize a lead compound and transfer the information from the theoretical and methodological areas to those more professional.
Prerequisites
THE STUDENT HAS TO KNOW THE ESSENTIAL CONCEPTS OF ORGANIC CHEMISTRY, MEDICINAL CHEMISTRY, BIOCHEMISTRY AND PHARMACOLOGY.
Contents
DRUG DISCOVERY: IDENTIFICATION AND OPTIMIZATION OF A "LEAD" COMPOUND. FUNDAMENTALS OF DRUG DESIGN. PEPTIDES AND PEPTIDOMIMETIC. PEPTIDE SYNTHESIS: GENERAL APPROACHES. COMBINATORIAL CHEMISTRY.
NEW FRONTIERS IN DRUG DEVELOPMENT: INNOVATIVE PEPTIDE AND BIOTECHNOLOGICAL DRUGS
Teaching Methods
LECTURES
Verification of learning
THE ACHIEVEMENT OF THE OBJECTIVES OF THE COURSE IS CERTIFIED BY PASSING A N ORAL TEST BY A DISCUSSION LASTING ABOUT 25 MINUTES TO ENSURE THE LEVEL OF KNOWLEDGE AND UNDERSTANDING ACQUIRED BY THE STUDENT ON THE THEORETICAL AND METHODOLOGICAL CONTENT INDICATED IN THE PROGRAM.
Texts
LECTURE NOTES, SLIDES.
W.O. FOYE: “PRINCIPI DI CHIMICA FARMACEUTICA”, PICCIN.
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