CHEMICAL RISK IN THE LABORATORY

Gianluigi LAURO CHEMICAL RISK IN THE LABORATORY

0760400051
DIPARTIMENTO DI FARMACIA
EQF7
PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY
2024/2025

YEAR OF COURSE 3
YEAR OF DIDACTIC SYSTEM 2023
AUTUMN SEMESTER
CFUHOURSACTIVITY
324LESSONS
Objectives
THE COURSE PROVIDES STUDENTS WITH THE KNOWLEDGE FOR THE IDENTIFICATION OF CHEMICALS THAT MAY REPRESENT A SOURCE OF RISK IN THE LABORATORY.
KNOWLEDGE AND UNDERSTANDING
AT THE END OF THE CLASS, STUDENTS WILL ACQUIRE KNOWLEDGE RELATED TO THE DIFFERENT TYPES OF RISKS IN THE CHEMICAL LABORATORY, WITH PARTICULAR REGARD ON THE CHEMICAL RISK. NOTIONS WILL ALSO BE ACQUIRED REGARDING THE SAFETY PROCEDURES TO BE FOLLOWED RELATED TO THE USE OF HAZARDOUS SUBSTANCES.
APPLYING KNOWLEDGE AND UNDERSTANDING
AT THE END OF THE CLASS, STUDENTS WILL KNOW HOW TO:
- IDENTIFY CHEMICAL SUBSTANCES AND MIXTURES THAT MAY THREATEN SAFETY AND HEALTH AND ASSESS CRITICAL ISSUES IN THE LABORATORY IN RELATION TO THE RISK OF EXPOSURE TO UNSTABLE AND HAZARDOUS SUBSTANCES (E.G., EXPLOSIVE, FLAMMABLE, TOXIC SUBSTANCES AND MIXTURES);
- ADEQUATELY INTERPRET LABELS AND MSDSS ASSOCIATED WITH HAZARDOUS CHEMICAL COMPOUNDS AND THEIR PICTOGRAMS;
- APPLY APPROPRIATE STANDARDS OF BEHAVIOR RELATED TO SAFETY IN THE CHEMICAL LABORATORY.
MAKING JUDGMENTS
STUDENTS WILL BE ABLE TO:
- DEVELOP CRITICAL SKILLS IN HANDLING HAZARDOUS SUBSTANCES;
- PROPOSE CHEMICAL SUBSTANCE ALTERNATIVES IN ORDER TO MINIMIZE THE USE OF HAZARDOUS SUBSTANCES;
- RESEARCH AND ANALYZE SCIENTIFIC DATA IN ORDER TO BE ABLE TO PROPOSE EFFECTIVE SOLUTIONS.
COMMUNICATION SKILLS
STUDENTS WILL BE ABLE TO:
- DESCRIBE IN DETAIL THE RISKS ASSOCIATED WITH THE USE OF HAZARDOUS SUBSTANCES;
- DESCRIBE THE RISK CONTAINMENT MEASURES ASSOCIATED WITH THE USE OF HAZARDOUS SUBSTANCES;
- DESCRIBE THE EFFECTS RESULTING FROM THE USE OF HAZARDOUS SUBSTANCES;
- DESCRIBE THE PERSONAL AND COLLECTIVE PROTECTIVE EQUIPMENT TO BE USED IN THE CHEMICAL LABORATORY, THEIR OPERATION AND/OR SCOPE OF APPLICATION, AND HOW TO USE THEM;
- COMMUNICATE ACQUIRED KNOWLEDGE IN WRITTEN AND ORAL FORM WITH CORRECT TECHNICAL AND SCIENTIFIC LANGUAGE.
ABILITY TO LEARN
STUDENTS WILL BE ABLE TO:
- UPDATE THEIR KNOWLEDGE OF RISK IN THE CHEMICAL LABORATORY;
- UNDERSTAND AND INTERPRET LITERATURE PAPERS RELATED TO RISK IN THE CHEMICAL LABORATORY.
Prerequisites
THE ATTAINMENT OF THE LEARNING OBJECTIVES RELATED TO THE FOLLOWING DISCIPLINES IS ADVISABLE: INORGANIC CHEMISTRY, ORGANIC CHEMISTRY I AND II
Contents
INTRODUCTION TO THE RISK ASSESSMENT AND RISK REDUCTION IN THE CHEMICAL LABORATORY (2 HOURS)
PHYSICAL RISK IN THE LABORATORY (2 HOURS)
LABELING AND MSDS. INTERPRETATION AND EVALUATION OF PICTOGRAMS AND H AND P PHRASES (2 HOURS)
CLASSIFICATION OF HAZARDOUS SUBSTANCES WITH REFERENCE TO THE CLP REGULATION (2 HOURS)
REACTIVE AND INCOMPATIBLE SUBSTANCES (2 HOURS)
RISK ASSOCIATED WITH THE USE OF SOLVENTS IN THE CHEMICAL LABORATORY (2 HOURS)
CHARACTERISTICS AND MAIN PARAMETERS OF COMBUSTION REACTIONS. FLAMMABLE SUBSTANCES (2 HOURS)
FLAMMABLE SUBSTANCES (2 HOURS)
EXPLOSIVE SUBSTANCES (2 HOURS)
COMPRESSED GASES AND CRYOGENIC LIQUIDS (2 HOURS)
ALGORITHMS OF CHEMICAL RISK ASSESSMENT (2 HOURS)
ORGANIC SYNTHESIS PROCEDURES AIMED AT REDUCING CHEMICAL RISK IN THE LABORATORY (4 HOURS)
Teaching Methods
THE CLASS INVOLVES FACE-TO-FACE LECTURES (24 HOURS, 3 CFU). THE TEACHING METHOD RELIES ON THE CONTRIBUTION OF PROJECTED SLIDES AND THE USE OF TEXTS DEDICATED TO THE IN-DEPTH STUDY OF THE TOPICS. AS PER THE TEACHING REGULATIONS, ATTENDANCE OF THE COURSE IS MANDATORY. THE ATTENDANCE WILL BE ELECTRONICALLY DETECTED. TO PASS THE FINAL EXAM, THE STUDENT MUST HAVE ATTENDED AT LEAST 70 PERCENT OF THE HOURS COVERED BY THE COURSE.
Verification of learning
THE ASSESSMENT OF COMPETENCE WILL BE DEFINED BY A POSITIVE MARK (WITHOUT GRADE). THE FINAL ASSESSMENT OF PREPARATION WILL CONSIST:
IN A WRITTEN TEST, BASED ON MULTIPLE-CHOICE QUESTIONS (30 QUESTIONS) AND OPEN-ENDED QUESTIONS (5 QUESTIONS).
THERE WILL ALSO BE AT LEAST TWO WRITTEN IN ITINERE TESTS DURING THE COURSE, AGAIN BASED ON MULTIPLE-CHOICE QUESTIONS (30 QUESTIONS) AND OPEN-ENDED QUESTIONS (3 QUESTIONS). IN THIS CASE, IF PASSED, THEY WILL ALLOW ACCESS TO A DIFFERENT FINAL WRITTEN TEST THAT WILL FOLLOW A MULTIPLE-CHOICE/OPEN-ENDED QUESTIONS BALANCE SIMILAR TO THAT OF THE IN ITINERE TESTS
THE WRITTEN TESTS ALLOW TO VERIFY THE LEVEL OF LEARNING OF KNOWLEDGE, CORRECT TERMINOLOGY, ABILITY TO ANALYZE. THE ASSESSMENT TAKES INTO ACCOUNT OVERALL:
- LEVEL OF KNOWLEDGE ACQUIRED;
- ABILITY TO SYNTHESIS AND EXPOSITION, APPROPRIATENESS OF LANGUAGE;
- ANALYTICAL SKILLS.
THE METHODS OF VERIFICATION ARE CONSIDERED APPROPRIATE IN RELATION TO THE OBJECTIVES OF TEACHING, AND TO THE EXPECTED KNOWLEDGE AND SKILLS.
Texts
- SLIDES AND NOTES FROM THE LESSONS
- PHILIP CARSON E CLIVE MUMFORS - HAZARDOUS CHEMICALS HANDBOOK - SECOND EDITION
- PAPERS CITED IN THE SLIDES
- NORMATIVE REFERENCES CITED IN THE SLIDES
More Information
STUDENTS ARE ALSO STIMULATED TO COMMENT ON CASE STUDIES PROPOSED IN AUTONOMY AND SHARED WITH THE TEACHER
Lessons Timetable

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