Gianluigi LAURO | BIOORGANIC CHEMISTRY OF ENZYMES
Gianluigi LAURO BIOORGANIC CHEMISTRY OF ENZYMES
cod. 0760300051
BIOORGANIC CHEMISTRY OFENZYMES
| 0760300051 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACY | |
| 2025/2026 |
| YEAR OF COURSE 3 | |
| YEAR OF DIDACTIC SYSTEM 2023 | |
| AUTUMN SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| CHIM/06 | 3 | 24 | LESSONS |
| Objectives | |
|---|---|
| THE COURSE AIMS TO PROVIDE THE STUDENT WITH A DEEPER KNOWLEDGE OF THE MOLECULAR MECHANISMS THAT GOVERN THE INTERACTIONS AND REACTIONS IN BIOLOGICAL SYSTEMS AND OF THE REACTIONS IN WHICH ENZYMES ARE INVOLVED. AT THE END OF THE COURSE THE STUDENT WILL KNOW THE ORGANIC CHEMICAL MECHANISMS AT THE BASIS OF THE REACTIVITY OF THE MAIN ENZYMES SUCH AS SERINE PROTEASE, ASPARTATE PROTEASE, CARBOXY PEPTIDASE, LACTIC DEHYDROGENASE, GSH, HDAC, LYSOZYME ETC ETC AT THE END OF THE COURSE, BY APPLYING THE SKILLS ACQUIRED, THE STUDENT SHOULD BE ABLE TO DEVELOP THE CHEMICAL-PHYSICAL PRINCIPLES FOR THE ANALYSIS OF MOLECULAR INTERACTIONS IN BIOLOGICAL SYSTEMS IN WHICH ENZYMES ARE INVOLVED. |
| Prerequisites | |
|---|---|
| THE ACQUISITION OF THE OBJECTIVES RELATING TO THE FOLLOWING SUBJECTS IS ADVISABLE: PHYSICS, GENERAL CHEMISTRY, ORGANIC CHEMISTRY, BIOCHEMISTRY. |
| Contents | |
|---|---|
| METABOLISM AND BIOENERGETICS 2H. THERMODYNAMICS AND CHEMISTRY OF THE PEPTIDE BOND 2H. CHEMICAL AND BIOLOGICAL ROLE OF PHOSPHATE GROUPS 2H MECHANISM OF ENZYME ACTION: SERINE PROTEASE 2H, LYSOZYME 2H, ASPARTIC PROTEASE 2H, GSSG REDATTASI 2H, HDAC 2H, ALCOHOL DEHYDROGENASE 2H, CARBOXY-PEPTIDASE ENZYME INHIBITORS 2H. BIOCATALYSIS AND USE OF ENZYMES IN ORGANIC SYNTHESIS. 2H |
| Teaching Methods | |
|---|---|
| TEACHING INVOLVES 24 HOURS (3 CFU). THE TEACHING METHOD IS BASED ON FRONTAL LECTURES AND MAKES USE OF THE CONTRIBUTION OF PROJECTED SLIDES TO GUIDE THE EDUCATIONAL PATH AND THE ADOPTION OF TEXTS DEDICATED TO IN-DEPTH THEMES. ATTENDANCE AT LECTURES IS MANDATORY. THE ATTENDANCE WILL BE ELECTRONICALLY DETECTED AS PLANNED BY ATHENAEUM (EASYBADGE PLATFORM). |
| Verification of learning | |
|---|---|
| THE EXAMINATION CONSISTS OF A WRITTEN TEST. THE WRITTEN TEST CONSISTS IN THE ADMINISTRATION OF A QUESTIONNAIRE OF OPEN-ENDED QUESTIONS RELATED TO THE SCOPE OF THE PROGRAM AND SHOULD BE COMPILED WITHIN 120 MINUTES. THE QUESTIONNAIRE CONSISTS OF OPEN-RESPONSE QUESTIONS (AT LEAST 3 QUESTIONS) IN WHICH IT IS NECESSARY TO DESCRIBE THE TOPICS AND STRUCTURES OF THE MOLECULES INVOLVED WITH PROPER PREPARATION. TO OVERCOME THE EXAMINATION IT IS NECESSARY TO KNOW THE MOLECULAR STRUCTURES OF COMPOUNDS AND REACTIONS INVOLVED IN ENZYMATIC REACTIONS IN DETAIL. THE WRITTEN TEST ARE USED TO VERIFY THE LEVEL OF LEARNING OF KNOWLEDGE, THE CORRECT TERMINOLOGY, THE CAPACITY FOR ANALYSIS, WHICH SHOULD BE THE KNOWLEDGE ACQUIRED. THE ASSESSMENT TAKES INTO ACCOUNT A TOTAL OF: LEVEL OF KNOWLEDGE ACQUIRED; CAPACITY OF SYNTHESIS AND EXPOSURE, APPROPRIATENESS OF LANGUAGE; CAPACITY OF ANALYSIS. THE VERIFICATION PROCEDURES ARE DEEMED APPROPRIATE IN RELATION TO THE TEACHING OBJECTIVES, AND ALSO TO THE KNOWLEDGE AND SKILLS EXPECTED. THE FINAL ASSESSMENT WILL TAKE ACCOUNT OF THE LEARNING PROGRESS RECORDED BY THE STUDENT. |
| Texts | |
|---|---|
| LECTURE NOTES, R. H. GARRETT, C. M. GRISHAM, BIOCHEMISTRY |
| More Information | |
|---|---|
| THE COURSE IS TAUGHT IN ITALIAN THE ATTENDANCE IS MANDATORY LOCATION: DEPARTMENT OF PHARMACY |
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