Rosanna MARTINELLI | BASIC BIOCHEMISTRY BIOLOGY AND MICROBIOLOGY
Rosanna MARTINELLI BASIC BIOCHEMISTRY BIOLOGY AND MICROBIOLOGY
cod. 1012100001
BASIC BIOCHEMISTRY BIOLOGY AND MICROBIOLOGY
1012100001 | |
DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA" | |
EQF6 | |
NURSING | |
2016/2017 |
OBBLIGATORIO | |
YEAR OF COURSE 1 | |
YEAR OF DIDACTIC SYSTEM 2013 | |
PRIMO SEMESTRE |
SSD | CFU | HOURS | ACTIVITY | ||
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NOZIONI DI BIOCHIMICA BIOLOGIA E MICROBIOLOGIA - MOD BIOCHIMICA | |||||
BIO/10 | 2 | 24 | LESSONS | ||
NOZIONI DI BIOCHIMICA BIOLOGIA E MICROBIOLOGIA - MOD MICROBIOLOGIA | |||||
MED/07 | 1 | 12 | LESSONS | ||
NOZIONI DI BIOCHIMICA BIOLOGIA E MICROBIOLOGIA - MOD BIOLOGIA APPLICATA | |||||
BIO/13 | 1 | 12 | LESSONS |
Objectives | |
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AT THE END OF THE COURSE THE STUDENT WILL KNOW THE STRUCTURE OF THE MAIN MOLECULES OF BIOCHEMICAL INTEREST AND HAVE UNDERSTOOD THE BASIC PRINCIPLES OF BIOENERGETICS FOR THE STUDY OF METABOLISM. MOREOVER IT SHOULD KNOW THE MAIN TECHNOLOGIES USED IN MOLECULAR DIAGNOSTICS. |
Prerequisites | |
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NONE |
Contents | |
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ELEMENTS OF CHEMISTRY: PHYSICAL QUANTITIES AND UNITS OF MEASURE; MULTIPLES AND SUBMULTIPLES; PROPERTIES OF MATTER, HOMOGENEOUS AND HETEROGENEOUS SYSTEMS; THE CHEMICAL BONDS; ELECTRONEGATIVITY; IONIC BOND; COVALENT BOND; HYDROGEN BOND; STATES OF MATTER; CHEMICAL REACTIONS, CHEMICAL EQUILIBRIUM; SOLUTIONS; SOLUBILITY; COLLIGATIVE PROPERTIES OF SOLUTIONS; THE CONCENTRATIONS OF THE SOLUTIONS; THE WATER; PH AND BUFFER SOLUTIONS. THE CELL UNIT OF LIFE: THE AIM OF BIOCHEMISTRY; PROKARYOTIC AND EUKARYOTIC CELLS; THE MAIN BIOCHEMICAL COMPONENTS OF THE HUMAN BODY; CELLULAR LOCALIZATION OF METABOLIC PROCESSES. AMINO ACIDS AND PROTEINS: STRUCTURAL PROPERTIES AND CLASSIFICATION OF AMINO ACIDS; THE PEPTIDE BOND; PROTEIN STRUCTURE: PRIMARY, SECONDARY, TERTIARY AND QUATERNARY; MYOGLOBIN AND HEMOGLOBIN. ENZYMES: GENERAL PROPERTIES OF ENZYMES; ENZYME KINETICS; ENZYME INHIBITION; MULTISUBSTRATE REACTIONS; REGULATION OF ENZYME ACTIVITY; CLINICAL SIGNIFICANCE OF ENZYMES. NUCLEOTIDE AND NUCLEIC ACIDS: STRUCTURE OF NUCLEIC ACIDS, DNA; RNA; MOLECULAR DIAGNOSTICS; MUTATIONS; PURIFICATION OF NUCLEIC ACIDS; RESTRICTION ENZYMES; PCR; ELECTROPHORESIS. BIOENERGETICS AND METABOLISM: BIOENERGETICS AND TYPES OF BIOCHEMICAL REACTIONS; PRINCIPLES OF METABOLIC REGULATION GLYCOLYSIS: THE CHEMISTRY OF CARBOHYDRATES; THE DIGESTION OF CARBOHYDRATES; THE GLYCOLYTIC PATHWAY. KREBS CYCLE: DECARBOXYLATION REACTIONS; OVERVIEW OF THE KREBS CYCLE; YIELD OF ATP; REGULATION OF THE OXIDATION OF PYRUVATE AND ACETYL-COA; CLINICAL ASPECTS OF OXIDATIVE METABOLISM. AMINO ACID OXIDATION: METABOLIC FATE OF AMINO GROUPS; NITROGEN EXCRETION AND UREA CYCLE . |
Teaching Methods | |
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LECTURES |
Verification of learning | |
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WRITTEN AND ORAL EXAM |
Texts | |
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SUGGESTED TEXT: INTRODUZIONE ALLA BIOCHIMICA DI LEHNINGER. NELSON D.L., COX MM. ZANICHELLI TEACHING MATERIALS: SLIDES OF THE LECTURES. |
More Information | |
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NONE |
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