VALENTINA GIUDICE | RADIOTHERAPY

cod. 1012500018

RADIOTHERAPY

	1012500018
	DEPARTMENT OF MEDICINE, SURGERY AND DENTISTRY "SALERNITANA MEDICAL SCHOOL"
	EQF6
	IMAGING AND RADIOTHERAPY TECHNIQUES
	2023/2024

PERCORSO STUDY PATHWAY IN COMMON IN IMAGING AND RADIOTHERAPY TECHNIQUES

	OBBLIGATORIO
	YEAR OF COURSE 2
	YEAR OF DIDACTIC SYSTEM 2017
	SPRING SEMESTER

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	RADIOTERAPIA - MOD. APPARECCHIATURE DI RT E RT CLINICA
	MED/36	2	24	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	RADIOTERAPIA - MOD. TERAPIA CON RADIONUCLIDI
	MED/36	1	12	SEMINAR	VARIOUS EDUCATIONAL ACTIVITIES
3	RADIOTERAPIA - MOD. MALATTIE DEL SANGUE
	MED/15	1	12	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
4	RADIOTERAPIA - MOD. ONCOLOGIA MEDICA
	MED/06	1	12	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
5	RADIOTERAPIA - MOD. ASPETTI TECNICO-MEDOLOGICI DI RADIOTERAPIA 2
	MED/50	1	12	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	LEONARDO PACE2 T Curriculum
	DAVIDE DI GENNARO1 Curriculum
	VALENTINA GIUDICE3 Curriculum
	FRANCESCO SABBATINO4 Curriculum
	ANNA BERNADETTE SORRENTINO5 Curriculum

	Objectives
	THE RADIOTHERAPY COURSE IS DIVIDED INTO FIVE TEACHING MODULES: RADIOTHERAPY EQUIPMENT AND CLINICAL RADIOTHERAPY, RADIONUCLIDE THERAPY, BLOOD DISEASES, MEDICAL ONCOLOGY, TECHNICAL-METHODOLOGICAL ASPECTS OF THE I.C. THE COURSE AIMS TO PROMOTE THE ACQUISITION OF THEORETICAL KNOWLEDGE CONCERNING THE FUNDAMENTAL ELEMENTS OF RADIOTHERAPY AND RADIONUCLIDE THERAPY, AS WELL AS PROVIDING THE FUNDAMENTAL ELEMENTS OF THE MAIN ONCOLOGICAL AND ONCO-HAEMATOLOGICAL PATHOLOGIES. KNOWLEDGE AND UNDERSTANDING - KNOWLEDGE AND UNDERSTANDING OF THE THEORETICAL AND METHODOLOGICAL ASPECTS OF RADIOTHERAPY - KNOWLEDGE AND UNDERSTANDING OF THE THEORETICAL AND METHODOLOGICAL ASPECTS OF RADIONUCLIDE THERAPY -KNOWLEDGE AND UNDERSTANDING OF THE MAIN ONCO-HAEMATOLOGICAL PATHOLOGIES - UNDERSTAND HOW BIOLOGICAL DIFFERENCES (DEFINED BY GENDER) AND SOCIO-ECONOMIC AND CULTURAL DIFFERENCES (DEFINED BY GENDER) BY INFLUENCING THE ETIOPATHOGENESIS, PATHOPHYSIOLOGY AND SYMPTOMATOLOGY OF PATHOLOGIES AFFECT THE DEFINITION OF APPROPRIATENESS OF RADIOTHERAPY PROCEDURES ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING - ABILITY TO DISTINGUISH BETWEEN DIFFERENT RADIOTHERAPY METHODS - ABILITY TO IDENTIFY THE APPROPRIATE RADIOTHERAPY METHODS FOR DIFFERENT PATHOLOGIES TRANSVERSAL SKILLS - ABILITY TO UPDATE THROUGH BIBLIOGRAPHIC TOOLS.

THE RADIOTHERAPY COURSE IS DIVIDED INTO FIVE TEACHING MODULES: RADIOTHERAPY EQUIPMENT AND CLINICAL RADIOTHERAPY, RADIONUCLIDE THERAPY, BLOOD DISEASES, MEDICAL ONCOLOGY, TECHNICAL-METHODOLOGICAL ASPECTS OF THE I.C. THE COURSE AIMS TO PROMOTE THE ACQUISITION OF THEORETICAL KNOWLEDGE CONCERNING THE FUNDAMENTAL ELEMENTS OF RADIOTHERAPY AND RADIONUCLIDE THERAPY, AS WELL AS PROVIDING THE FUNDAMENTAL ELEMENTS OF THE MAIN ONCOLOGICAL AND ONCO-HAEMATOLOGICAL PATHOLOGIES.
KNOWLEDGE AND UNDERSTANDING
- KNOWLEDGE AND UNDERSTANDING OF THE THEORETICAL AND METHODOLOGICAL ASPECTS OF RADIOTHERAPY
- KNOWLEDGE AND UNDERSTANDING OF THE THEORETICAL AND METHODOLOGICAL ASPECTS OF RADIONUCLIDE THERAPY
-KNOWLEDGE AND UNDERSTANDING OF THE MAIN ONCO-HAEMATOLOGICAL PATHOLOGIES
- UNDERSTAND HOW BIOLOGICAL DIFFERENCES (DEFINED BY GENDER) AND SOCIO-ECONOMIC AND CULTURAL DIFFERENCES (DEFINED BY GENDER) BY INFLUENCING THE ETIOPATHOGENESIS, PATHOPHYSIOLOGY AND SYMPTOMATOLOGY OF PATHOLOGIES AFFECT THE DEFINITION OF APPROPRIATENESS OF RADIOTHERAPY PROCEDURES
ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING
- ABILITY TO DISTINGUISH BETWEEN DIFFERENT RADIOTHERAPY METHODS
- ABILITY TO IDENTIFY THE APPROPRIATE RADIOTHERAPY METHODS FOR DIFFERENT PATHOLOGIES
TRANSVERSAL SKILLS
- ABILITY TO UPDATE THROUGH BIBLIOGRAPHIC TOOLS.

	Prerequisites
	N ORDER TO UNDERSTAND AND KNOW HOW TO APPLY MOST OF THE TOPICS COVERED IN THE TEACHING, IT IS NECESSARY TO HAVE PASSED THE PRELIMINARY EXAMINATIONS: C.I. APPARECCHIATURE 1 C.I. APPARECCHIATURE 2

	Contents
	CONTENTS. THE TEACHING IS DIVIDED INTO 5 MODULES: RADIOTHERAPY EQUIPMENT AND CLINICAL RADIOTHERAPY WITH 2 CFU, RADIONUCLIDE THERAPY WITH 1 CFU, BLOOD DISEASES WITH 1 CFU, ONCOLOGY WITH 1 CFU, RADIOTHERAPY METHODS WITH 1 CFU. THE COURSE INCLUDES 60 HOURS OF LESSONS IN WHICH THE TOPICS WILL BE ADDRESSED: CLINICAL RADIOTHERAPY AND RADIOTHERAPY EQUIPMENT - INTRODUCTION TO RADIOTHERAPY. - PATIENT CLASSIFICATION. - CENTERING. - RADIOTHERAPY EQUIPMENT. - TREATMENT PLANS. - RADIOTHERAPY OF THE MAIN ONCOLOGICAL PATHOLOGIES. RADIONUCLIDE THERAPY - RADIONUCLIDES OF INTEREST IN RADIOTHERAPY. - METHODOLOGY OF RADIONUCLIDE THERAPY. - INDICATIONS FOR RADIOTHERAPY WITH RADIONUCLIDES. - LEGISLATION. DISEASES OF THE BLOOD - THE BONE MARROW; - HEMOPOIESIS; - STEM CELLS; - ERYTHROPOIESIS; - PLATELETS; - RED BLOOD CELLS AND WHITE BLOOD CELLS; - THE ACUTE RADIATION SYNDROME; - MULTIPLE MYELOMA; - ROLE OF MRI IN MULTIPLE MYELOMA; - MRI OF THE BONE MARROW; - MRI LYMPHOMAS; - MEDULLARY HYPOPLASIA; - ANEMIAS; - HODGKIN'S AND NON-HODGKIN'S LYMPHOMAS: DIAGNOSIS AND THERAPY. ONCOLOGY - EPIDEMIOLOGY AND CANCER PREVENTION; - TUMOR GROWTH AND METASTATIC DISSEMINATION: - BIOLOGY OF TRANSFORMATION AND NEOPLASTIC GROWTH; - THE PROCESS OF METASTASIS; - INVASION: DEGRADATION, REMODELING OF THE EXTRACELLULAR MATRIX; - METASTATIC PROGRESSION; - TUMOR QUIESCENCE; - NORMAL AND NEOPLASTIC ANGIOGENESIS. - PRINCIPLES OF ANTICANCER THERAPY: - SURGICAL THERAPY; - RADIANT THERAPY; -MEDICAL THERAPY. -MEDICAL THERAPY: - SPECIFIC MOLECULAR TARGET THERAPY; - CHEMOTHERAPY; - MONOCLONAL ANTIBODIES; - INTEGRATED TREATMENTS AND SIDE EFFECTS METHODOLOGIES - THE ACTORS OF RADIOTHERAPY - PURPOSE OF RADIOTHERAPY - RADIOPATHOLOGY - RADIOTHERAPY EQUIPMENT: THE TRADITIONAL SIMULATOR, THE VIRTUAL SIMULATOR, ROENTGENT THERAPY EQUIPMENT, PLEXIOTHERAPY EQUIPMENT - THE LINEAR ACCELERATOR: LINAC - THE GAMMAKNIFE - THE CYBERKNIFE - PORTABLE ACCELERATORS - TOMOTHERAPY - USEFUL DEFINITIONS AND OPERATING PROCEDURES FOR EXTERNAL BEAM RADIOTHERAPY - ICRU - TREATMENT VOLUMES - SIMULATION OF THERAPY - IMMOBILIZATION SYSTEMS - THERAPY PLANNING - SET-UP VERIFICATION SYSTEMS, IGRT - EXTERNAL BEAM RADIOTHERAPY - CONVENTIONAL 2D RADIOTHERAPY - 3DCT CONFORMAL RADIOTHERAPY - IMRT MODULATED INTENSITY RADIOTHERAPY - ELECTRON RADIATION THERAPY - VOLUMETRIC TECHNIQUES - TOMOTHERAPY - IMAT TECHNIQUES - SPECIAL TECHNIQUES WITH EXTERNAL BEAMS - • TOTAL BODY IRRADIATION, TBI - • TOTAL SKINELECTRON BEAMIRRADIATION, TSEBI - • INTRA-OPERATIVE RADIO THERAPY, IORT - • STEREOTAXIC RADIOTHERAPY - BRACHYTHERAPY - TYPES OF SYSTEMS - DOSE INTENSITY - RADIOACTIVE ISOTOPES USED - BRACHYTHERAPY TECHNIQUES - METHODS OF BRACHYTHERAPY - RADIATION PROTECTION IN BRACHYTHERAPY - PALLIATIVE RADIOTHERAPY - PRINCIPLES OF PALLIATION - MORE FREQUENT APPLICATIONS - ONCOLOGICAL EMERGENCIES IN RADIOTHERAPY - HINTS TO RADIOTHERAPY TREATMENTS - BREAST - PROSTATE - COLORECTAL - GYNECOLOGICAL SYSTEM

Contents

CONTENTS. THE TEACHING IS DIVIDED INTO 5 MODULES: RADIOTHERAPY EQUIPMENT AND CLINICAL RADIOTHERAPY WITH 2 CFU, RADIONUCLIDE THERAPY WITH 1 CFU, BLOOD DISEASES WITH 1 CFU, ONCOLOGY WITH 1 CFU, RADIOTHERAPY METHODS WITH 1 CFU. THE COURSE INCLUDES 60 HOURS OF LESSONS IN WHICH THE TOPICS WILL BE ADDRESSED:
CLINICAL RADIOTHERAPY AND RADIOTHERAPY EQUIPMENT
- INTRODUCTION TO RADIOTHERAPY.
- PATIENT CLASSIFICATION.
- CENTERING.
- RADIOTHERAPY EQUIPMENT.
- TREATMENT PLANS.
- RADIOTHERAPY OF THE MAIN ONCOLOGICAL PATHOLOGIES.
RADIONUCLIDE THERAPY
- RADIONUCLIDES OF INTEREST IN RADIOTHERAPY.
- METHODOLOGY OF RADIONUCLIDE THERAPY.
- INDICATIONS FOR RADIOTHERAPY WITH RADIONUCLIDES.
- LEGISLATION.
DISEASES OF THE BLOOD
- THE BONE MARROW;
- HEMOPOIESIS;
- STEM CELLS;
- ERYTHROPOIESIS;
- PLATELETS;
- RED BLOOD CELLS AND WHITE BLOOD CELLS;
- THE ACUTE RADIATION SYNDROME;
- MULTIPLE MYELOMA;
- ROLE OF MRI IN MULTIPLE MYELOMA;
- MRI OF THE BONE MARROW;
- MRI LYMPHOMAS;
- MEDULLARY HYPOPLASIA;
- ANEMIAS;
- HODGKIN'S AND NON-HODGKIN'S LYMPHOMAS: DIAGNOSIS AND THERAPY.
ONCOLOGY
- EPIDEMIOLOGY AND CANCER PREVENTION;
- TUMOR GROWTH AND METASTATIC DISSEMINATION:
- BIOLOGY OF TRANSFORMATION AND NEOPLASTIC GROWTH;
- THE PROCESS OF METASTASIS;
- INVASION: DEGRADATION, REMODELING OF THE EXTRACELLULAR MATRIX;
- METASTATIC PROGRESSION;
- TUMOR QUIESCENCE;
- NORMAL AND NEOPLASTIC ANGIOGENESIS.
- PRINCIPLES OF ANTICANCER THERAPY:
- SURGICAL THERAPY;
- RADIANT THERAPY;
-MEDICAL THERAPY.
-MEDICAL THERAPY:
- SPECIFIC MOLECULAR TARGET THERAPY;
- CHEMOTHERAPY;
- MONOCLONAL ANTIBODIES;
- INTEGRATED TREATMENTS AND SIDE EFFECTS
METHODOLOGIES
- THE ACTORS OF RADIOTHERAPY
- PURPOSE OF RADIOTHERAPY
- RADIOPATHOLOGY
- RADIOTHERAPY EQUIPMENT: THE TRADITIONAL SIMULATOR, THE VIRTUAL SIMULATOR, ROENTGENT THERAPY EQUIPMENT, PLEXIOTHERAPY EQUIPMENT
- THE LINEAR ACCELERATOR: LINAC
- THE GAMMAKNIFE
- THE CYBERKNIFE
- PORTABLE ACCELERATORS
- TOMOTHERAPY
- USEFUL DEFINITIONS AND OPERATING PROCEDURES FOR EXTERNAL BEAM RADIOTHERAPY
- ICRU
- TREATMENT VOLUMES
- SIMULATION OF THERAPY
- IMMOBILIZATION SYSTEMS
- THERAPY PLANNING
- SET-UP VERIFICATION SYSTEMS, IGRT
- EXTERNAL BEAM RADIOTHERAPY
- CONVENTIONAL 2D RADIOTHERAPY
- 3DCT CONFORMAL RADIOTHERAPY
- IMRT MODULATED INTENSITY RADIOTHERAPY
- ELECTRON RADIATION THERAPY
- VOLUMETRIC TECHNIQUES
- TOMOTHERAPY
- IMAT TECHNIQUES
- SPECIAL TECHNIQUES WITH EXTERNAL BEAMS
- • TOTAL BODY IRRADIATION, TBI
- • TOTAL SKINELECTRON BEAMIRRADIATION, TSEBI
- • INTRA-OPERATIVE RADIO THERAPY, IORT
- • STEREOTAXIC RADIOTHERAPY
- BRACHYTHERAPY
- TYPES OF SYSTEMS
- DOSE INTENSITY
- RADIOACTIVE ISOTOPES USED
- BRACHYTHERAPY TECHNIQUES
- METHODS OF BRACHYTHERAPY
- RADIATION PROTECTION IN BRACHYTHERAPY
- PALLIATIVE RADIOTHERAPY
- PRINCIPLES OF PALLIATION
- MORE FREQUENT APPLICATIONS
- ONCOLOGICAL EMERGENCIES IN RADIOTHERAPY
- HINTS TO RADIOTHERAPY TREATMENTS
- BREAST
- PROSTATE
- COLORECTAL
- GYNECOLOGICAL SYSTEM

	Teaching Methods
	The course is divided into lectures (72 hours) that allow the student to acquire the knowledge and skills of the fundamental elements of Radiotherapy methods and the basics of oncology and oncohematology. Attendance of classroom lessons and laboratory exercises is mandatory. In order to take the final exam, the student must have attended at least 75% of the teaching hours. The modality of checking the presence is made known by the teacher at the beginning of the lessons.

Teaching Methods

The course is divided into lectures (72 hours) that allow the student to acquire the knowledge and skills of the fundamental elements of Radiotherapy methods and the basics of oncology and oncohematology. Attendance of classroom lessons and laboratory exercises is mandatory. In order to take the final exam, the student must have attended at least 75% of the teaching hours. The modality of checking the presence is made known by the teacher at the beginning of the lessons.

	Verification of learning
	The achievement of the teaching objectives is certified by passing an oral exam with an evaluation out of thirty. The test as a whole allows to ascertain both the ability to know and understand, and the ability to apply the skills acquired, both the ability to exhibit, and the ability to learn and develop solutions independently of judgment. The teachers holding the coordinated modules participate in the overall collegial assessment of the student's achievement.

Verification of learning

The achievement of the teaching objectives is certified by passing an oral exam with an evaluation out of thirty. The test as a whole allows to ascertain both the ability to know and understand, and the ability to apply the skills acquired, both the ability to exhibit, and the ability to learn and develop solutions independently of judgment. The teachers holding the coordinated modules participate in the overall collegial assessment of the student's achievement.

	Texts
	ELEMENTI DI RADIOTERAPIA ONCOLOGICA - MANUALE PER TECNICI SANITARI DI RADIOLOGIA MEDICA DI BALDUCCI - D'ANGELILLO - CORNACCHIONE - MATTIUCCI – PASINI, 2013 LECTURES NOTES EMATOLOGIA SMART AUTHOR: GIONA ISBN: 8879477714 EDITOR: IDELSON-GNOCCHI (2022)

	More Information
	THE DIFFERENCES OF GENDER WILL BE CONSIDERED IN THE CONTENTS OF THE TEACHING

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VALENTINA GIUDICE | RADIOTHERAPY