BIOACTIVE COMPOUNDS FROM PLANTS AND QUALITY CONTROL

Nunziatina DE TOMMASI BIOACTIVE COMPOUNDS FROM PLANTS AND QUALITY CONTROL

0760100032
DIPARTIMENTO DI FARMACIA
EQF7
PHARMACY
2017/2018

YEAR OF DIDACTIC SYSTEM 2010
PRIMO SEMESTRE
CFUHOURSACTIVITY
540LESSONS
Objectives
This teaching is aimed at obtaining knowledge and understanding of the biosynthetic approach to classify secondary metabolites of vegetable origin (such as phenols, terpenoids and alkaloids), of their biological activity, and of the quality control techniques of the herbal preparations.
The student applying the acquired skills will have to be able to relate the structures and physico-chemical properties of the main groups of plant secondary metabolites to their biological properties. The student should be able to discuss some aspect of the herbal preparation quality control.
Prerequisites
IT IS REQUIRED THE ACQUISITION OF THE OBJECTIVES RELATING TO THE FOLLOWING SUBJECTS: ORGANIC CHEMISTRY, PLANT BIOLOGY, MEDICAL BOTANY, AND BIOCHEMISTRY, SPECTROSCOPY
Contents
PRIMARY AND SECONDARY METABOLISM (DEFINITIONS) – BIOSYNTHETIC PATHWAYS IN VASCULAR PLANTS
PHENOLIC COMPOUNDS – BIOSYNTHESIS AND BIOACTIVITY - CLASSIFICATION AND CHARACTERIZATION OF PHENOLIC COMPOUNDS: PHENOLS,PHENYL PROPANOIDS, FLAVONOIDS, .PHENOLIC COMPOUNDS OF INTEREST IN THE PHARMACEUTICAL AND FOOD FIELDS
TERPENOIDS – BYOSINTHESIS AND BIOACTIVITY. CLASSIFICATION AND CHARACTERIZATION OF TERPENOIDS, MONOTERPENOIDS, SESQUITERPENOIDS, DITERPENOIDS, TRITERPENOIDS. TERPENOIDS OF INTEREST IN THE PHARMACEUTICAL AND FOOD FIELDS
ALKALOIDS – BYOSINTHESIS AND BIOACTIVITY –ALKALOIDS DERIVING FROM ORNITHINE, TYROSINE,AND TRYPTOPHAN; ALKALOIDS OF INTEREST IN THE PHARMACEUTICAL FIELD
Teaching Methods
LECTURES WILL BE CONDUCTED THROUGH THE AID OF A POWER POINT SUPPORT. IT IS PLANNED TO SHOW PRESENTATIONS FULL OF PICTURES, AND SCHEMES THAT ENABLE MAXIMUM UNDERSTANDING AND SYNTHESIS OF THE TOPICS COVERED, AS WELL AS PROGRESS TESTS.
Verification of learning
WRITTEN PAPER : 5 EXTENTED RESPONSE QUESTIONS (2 HOURS ) REGARDING THE MAIN LEARNING OUTCOMES.
THE ASSESSMENT OF THE SUCCESS OF THE EXAM BY MEANS OF SPECIFIC QUESTIONS, IT WILL BE DETERMINED WHETHER THE STUDENT HAS ACQUIRED GENERAL KNOWLEDGE OF THE COURSE CONTENTS, AND IF THE STUDENT GAINED THE ABILITY TO UNDERSTAND AND TO EXPLAIN THE MAIN BIOSYTNTHETIC PHATWAYS , AND HAS THE SKILLS TO RECOGNIZE AND DESCRIBE THE SECONDARY METABOLITE SIGNIFICANCE AND BIOACTIVITY . THE STUDENT DISCUSSING THE MAIN TOPICS OF THE COURSE, HAVE TO DEMONSTRATE CRITICAL THOUGHT AND AWARENESS OF THE STRUCTURE OF THE FIELD OF STUDY.
Texts
NOTES FROM LESSONS
-MATERIALS DISTRIBUTED IN CLASS
-ANY TEST BOOKS IN ACCORDANCE WITH THE PROGRAM
R. M. SILVERSTEIN, F.X. WEBSTER IDENTIFICAZIONE SPETTROSCOPICA DEI COMPOSTI ORGANICI, CASA EDITRICE AMBROSIANA.
DEWICK PAUL M., CHIMICA, BIOSINTESI E BIOATTIVITÀ DELLE SOSTANZE NATURALI 2/ED.- EDIZIONE ITALIANA A CURA DI ERNESTO FATTORUSSO [DEWICK - PICCIN EDITORE]
More Information
THE COURSE IS TAUGHT IN ITALIAN
PLACE OF THE LESSONS:DEPARTMENT OF PHARMACY
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