Alessandra LATTANZI | ADVANCED ORGANIC CHEMISTRY

cod. 0522300012

ADVANCED ORGANIC CHEMISTRY

	0522300012
	DIPARTIMENTO DI CHIMICA E BIOLOGIA "ADOLFO ZAMBELLI"

	CHEMISTRY
	2015/2016

PERCORSO COMUNE

	OBBLIGATORIO
	YEAR OF COURSE 1
	YEAR OF DIDACTIC SYSTEM 2010
	PRIMO SEMESTRE

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	CHIMICA ORGANICA AVANZATA MODULO A
	CHIM/06	7	56	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	CHIMICA ORGANICA AVANZATA MODULO B
	CHIM/06	2	24	EXERCISES	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
	CHIM/06	3	36	LAB	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	ALESSANDRA LATTANZI1 T Curriculum
	ANTONIO MASSA2 Curriculum

	Objectives
	A deeper knowledge of the most important reactions for the regio- and stereocontrolled formation of C-C and C=C bonds, as well as fundamental aspects of the reactivity of organometallic reagents, devoted to the preparation of complex molecules and/or to the functionalisation of organic substrates. Capability of exploitation of advanced analytical and spectroscopic techniques for the resolution of problems of preparative, mechanistic and stereochemical type.

A deeper knowledge of the most important reactions for the regio- and stereocontrolled formation of C-C and C=C bonds, as well as fundamental aspects of the reactivity of organometallic reagents, devoted to the preparation of complex molecules and/or to the functionalisation of organic substrates. Capability of exploitation of advanced analytical and spectroscopic techniques for the resolution of problems of preparative, mechanistic and stereochemical type.

	Prerequisites
	Passing the examinations “Organic Chemistry I” and “Organic Chemistry II” courses

	Contents
	GENERATION OF ENOLATES AND THEIR SYNTHETIC EQUIVALENTS.PROCESSES OF ALKYLATION, ACYLATION, CONJUGATE ADDITION AND ALDOL TYPE CONDENSATION OF ENOLATES AND THEIR SYNTHETIC EQUIVALENTS; MECHANISTIC AND STEREOCHEMICAL ASPECTS OF REGIO-, STEREO- AND ENANTIOCONTROLLED REACTIONS. OLEFINATION REACTIONS. REGIO- AND STEREOSELECTIVE PROCESSES OF OXYFUNCTIONALIZATION OF ORGANIC COMPOUNDS. REDUCTIONS OF ORGANIC COMPOUNDS CONTENT OF THE LABORATORY: C-C BOND FORMATION BY MEANS OF C-ALKYLATION C-C BOND FORMATION BY CONJUGATE ADDITION OF ENOLATES FUNCTIONAL GROUP EXCHANGE BY MEANS OF WITTIG REACTION ALCOHOL ACETOACETILATION BY THE USE OF A SYNTHON EQUIVALENT NUCLEOPHILIC CARBONYL ADDITION NMR IDENTIFICATION OF THE COMPOUNDS

Contents

GENERATION OF ENOLATES AND THEIR SYNTHETIC EQUIVALENTS.PROCESSES OF ALKYLATION, ACYLATION, CONJUGATE ADDITION AND ALDOL TYPE CONDENSATION OF ENOLATES AND THEIR SYNTHETIC EQUIVALENTS; MECHANISTIC AND STEREOCHEMICAL ASPECTS OF REGIO-, STEREO- AND ENANTIOCONTROLLED REACTIONS. OLEFINATION REACTIONS.
REGIO- AND STEREOSELECTIVE PROCESSES OF OXYFUNCTIONALIZATION OF ORGANIC COMPOUNDS. REDUCTIONS OF ORGANIC COMPOUNDS
CONTENT OF THE LABORATORY: C-C BOND FORMATION BY MEANS OF C-ALKYLATION
C-C BOND FORMATION BY CONJUGATE ADDITION OF ENOLATES
FUNCTIONAL GROUP EXCHANGE BY MEANS OF WITTIG REACTION
ALCOHOL ACETOACETILATION BY THE USE OF A SYNTHON EQUIVALENT
NUCLEOPHILIC CARBONYL ADDITION
NMR IDENTIFICATION OF THE COMPOUNDS

	Teaching Methods
	lectures, laboratory

	Verification of learning
	oral examination

	Texts
	F. A. Carey and R. J. Sundberg, Advanced Organic Chemistry, Plenum Press; New York and London (V ed.) J. March, Advanced Organic Chemistry, J. Wiley & Sons; New York (IV ed.) B.S. Furniss, A.J. Hannaford, P.W.G. Smith, A.R. Tatchell, VOGEL’s “ textbook of practical organic chemistry” Longman Scientific & Technical, Harlow (UK)

	More Information
	FOR MORE INFORMATION CONTACT: LATTANZI@UNISA.IT

BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2016-09-30]

Alessandra LATTANZI | ADVANCED ORGANIC CHEMISTRY