Anna Maria D'URSI | Projects

The effect of nicotine was monitored in neuroblastoma cells SH-SY5Y by analyzing the endo- and exo-metabolome, demonstrating that the metabolomics profile of cells pretreated with nicotine before the addition of Aβ peptide became more similar to that of untreated cells.

⿢Collect, preparation and metabolomic analysis of SMNο7 mice tissue to outline the specific-organ role of SMN gene in SMA pathology⿢Collection and preparation of biofluids (serum, urine, saliva, faeces) from fibromyalgia patients before and after ketogenic or low glycaemic index diet (LOGI)⿢Use of bioinformatics and biostatistics approach for metabolomics data analysis ⿢Integration of metab

Alzheimer's disease (AD), is the most common neurodegenerative disorder of the aging population resulting in progressive cognitive and functional decline. Accumulation of amyloid plaques around neuronal cells is considered a critical pathogenetic event and, in most cases, a hallmark of the pathology. In the attempt to identify anti-AD drug candidates, hundreds of molecules targeting Aß peptides ha