Anna Maria D'URSI | LABORATORY OF DRUG ANALYSIS
Anna Maria D'URSI LABORATORY OF DRUG ANALYSIS
cod. 0760300009
LABORATORY OF DRUG ANALYSIS
| 0760300009 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACY | |
| 2023/2024 |
| OBBLIGATORIO | |
| YEAR OF COURSE 2 | |
| YEAR OF DIDACTIC SYSTEM 2023 | |
| AUTUMN SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| CHIM/08 | 5 | 40 | LAB |
| Objectives | |
|---|---|
| The course aims to provide students with the basic knowledge to execute qualitative analyzes for the recognition of an inorganic drug. Thanks to single-seat laboratory exercises, it is proposed to provide basic practical lessons for the execution of routine laboratory practices to identify inorganic drugs. The student will acquire knowledge of the issues related to: -access to the chemical laboratory, particularly the safety rules; -handling of hazardous and non-hazardous chemicals, their physical form, their homogeneous and heterogeneous mixtures; -Practical and theoretical competencies for qualitative analysis of inorganic drugs. The student will be able to: -attend the chemical laboratory in the respect of the safety standards; identify and properly handle chemical laboratory equipment; acquire the practical skills to execute basic laboratory operations to identify inorganic drugs. |
| Prerequisites | |
|---|---|
| ACCURATE KNOWLEDGE OF INORGANIC CHEMISTRY AND STECHIOMETRY |
| Contents | |
|---|---|
| PERIODIC SYSTEM OF ELEMENTS, NOMENCLATURE (2 HOURS) IONIC EQUILIBRIA IN AQUEOUS SOLUTION (CONCEPT OF ELECTROLYTE, ELECTROLYTE DISSOCIATION, ACIDS AND BASES, STRENGTH OF AN ACID AND BASE AND THEIR MEASUREMENT, IONIZATION OF WATER, IONIC PRODUCT OF WATER, PH, PH CALCULATION FOR WEAK AND STRONG ACIDS AND BASES, SALT SOLUTIONS AND HYDROLYSIS, BUFFER SOLUTIONS, PH INDICATORS) (3 HOURS) PRECIPITATION EQUILIBRIA (SOLUBILITY AND SOLUBILITY PRODUCT KPS, EFFECT OF COMMON ION, PH, TEMPERATURE AND CONCENTRATION ON SOLUBILITY OF POORLY SOLUBLE SALTS) (2 HOURS) COMPLEX IONS (STRUCTURE AND NOMENCLATURE OF COMPLEXES, BINDING IN COMPLEXES, STABILITY AND INSTABILITY CONSTANTS, EQUILIBRIA OF COMPLEX IONS) (2 HOURS) DRY ASSAYS ( 2 HOURS) SYSTEMATIC ANALYSIS OF ANIONS (2 HOURS) SYSTEMATIC ANALYSIS OF CATIONS (I-VI GROUP) (8 HOURS) LABORATORY SAFETY(2 HOURS) HINTS ON PHARMACOPOEIA AND MAJOR INORGANIC SALTS OF PHARMACEUTICAL INTEREST (1 HOUR) LABORATORY EXERCISES (16 HOURS) SIMPLE PROCEDURES OF SAMPLE PRETREATMENT: DISSOLUTION, PRECIPITATION, FILTRATION, , PH MEASUREMENT, ANALYSIS OF CATIONIC AND ANIONIC SPECIES: - DRY ROUTE ANALYSIS: CARBONATES, ACETATES, BORATES, AMMONIUM ION. - WET ANALYSIS: SINGLE AND MIXTURE ANALYSIS OF CATIONS: AG+ AL3+ FE2+/ FE3+ CA2+ MG2+ - WET ANALYSIS: SINGLE AND MIXTURE ANALYSIS OF ANIONS: CL- BR- I-C2O42-PO43-SO42-NO3- - ANALYSIS OF CATIONS AND/OR ANIONS PRESENT IN A MIXTURE FOR PHARMACEUTICAL USE. |
| Teaching Methods | |
|---|---|
| -LECTURES - LAB PRATICAL LESSONS |
| Verification of learning | |
|---|---|
| THE EXAMINATION CONSISTS OF A PRACTICAL LABORATORY TEST, WHICH DOES NOT INVOLVE A GRADE IN THIRTIETHS. IT IS PRE-SELECTIVE FOR ACCESS TO THE THEORETICAL EXAMINATION. THE THEORETICAL EXAMINATION IS BASED ON AN ORAL INTERVIEW OF ABOUT 20 MINUTES ON THEORETICAL OR APPLIED ASPECTS ( EXERCISES) OF THE COURSE CONTENT. |
| Texts | |
|---|---|
| CHEMISTRY: INORGANIC QUALITATIVE ANALYSIS IN THE LABORATORY MANUALE DI ANALISI QUALITATIVA_GIUSEPPE CALIENDO_EDISES HARRIS DANIEL C. CHIMICA ANALITICA QUANTITATIVA, ZANICHELLI. SKOOG D. A, WEST D. M. & HOLLER F. J., FONDAMENTI DI CHIMICA ANALITICA, EDISES. ARANEO, LIVERANI - ANALISI CHIMICA QUALITATIVA, AMBROSIANA F. SAVELLI, O. BRUNO - ANALISI CHIMICO FARMACEUTICA, SOC. ED. PICCIN SHRIRERET AL.,- THE SYSTEMATIC IDENTIFICATION OF ORGANIC COMPOUNDS, SOC. ED. WILEY V. CAVRINI, V. ANDRISANO - ANALISI FARMACEUTICA –METODI DI RICONOSCIMENTO E DI SEPARAZIONE, SOC. ED. ESCULAPIO DAVID G. WATSON - ANALISI FARMACEUTICA, EDISES |
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