Agostino CASAPULLO | ORGANIC CHEMISTRY II
Agostino CASAPULLO ORGANIC CHEMISTRY II
cod. 0760400012
ORGANIC CHEMISTRY II
| 0760400012 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY | |
| 2024/2025 |
| OBBLIGATORIO | |
| YEAR OF COURSE 2 | |
| YEAR OF DIDACTIC SYSTEM 2023 | |
| SPRING SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| CHIM/06 | 9 | 72 | LESSONS |
| Objectives | |
|---|---|
| THE COURSE AIMS TO PROVIDE THE STUDENT A MORE IN-DEPTH TRAINING IN ORGANIC CHEMISTRY THAN THE FIRST BASIC COURSE, WITH PARTICULAR CONCERNING THE NOMENCLATURE, CHEMICAL PROPERTIES AND REACTIVITY OF POLYFUNCTIONAL COMPOUNDS; ABOUT THE MAIN CLASSES OF ORGANIC COMPOUNDS OF BIOLOGICAL RELEVANCE: CARBOHYDRATES, AMINO ACIDS AND PEPTIDES, LIPIDS; ABOUT THE MAIN HETEROCYCLIC SYSTEMS. KNOWLEDGE AND UNDERSTANDING AT THE END OF THE COURSE THE STUDENT WILL KNOW: - PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN CLASSES OF BIFUNCTIONAL COMPOUNDS: DIOLS; HYDROXY CARBONYL COMPOUNDS; ALPHA, BETA-UNSATURATED CARBONYLIC COMPOUNDS; DICARBONYL COMPOUNDS; - MECHANISMS, PROCEDURES AND APPLICATION POTENTIAL OF THE MAIN CLASSES OF REACTIONS OF ENOLATE AND ENAMINE ANIONS; PROPERTIES, REACTIVITY AND SYNTHETIC APPLICATIONS OF BETA-DICARBONYLIC COMPOUNDS AND, MORE IN GENERAL, OF COMPOUNDS WITH ACTIVE METHYLENE GROUPS; STRUCTURE AND REACTIVITY OF ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS; - MECHANISMS AND SYNTHETIC APPLICATIONS OF AROMATIC NUCLEOPHILIC SUBSTITUTION REACTIONS; STRUCTURE, PROPERTIES, METHODS OF SYNTHESIS AND REACTIVITY OF PHENOLS; STRUCTURES, PROPERTIES AND REACTIVITY OF THE MAIN POLYCYCLIC AROMATIC COMPOUNDS; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF ALIPHATIC AND AROMATIC AMINES; AROMATIC DIAZONIUM SALTS; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN AROMATIC HETEROCYCLIC SYSTEMS; - PROPERTIES, STEREOCHEMISTRY AND REACTIVITY OF MONOSACCHARIDES; OF THE MAIN DISACCHARIDES AND POLYSACCHARIDES; AMINO ACIDS PEPTIDES AND PROTEINS; LIPIDS. PERCYCLIC REACTIONS; APPLYING KNOWLEDGE AND UNDERSTANDING AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO DEVELOP SIMPLE SYNTHETIC SEQUENCES OF POLYFUNCTIONAL ORGANIC COMPOUNDS AND TO APPLY THE PRINCIPLES OF MODERN SYNTHETIC STRATEGIES SUCH AS APPROACHES FOR DISCONNECTION, FORMATION OF CARBON-CARBON BOND, PROTECTION DEPROTECTION OF FUNCTIONAL GROUPS. THE STUDENT WILL ALSO BE ABLE TO EVALUATE THE MOST COMMONLY USED STRATEGIES IN THE SYNTHESIS OF POLY SUBSTITUTED AROMATIC COMPOUNDS. MAKING JUDGMENTS: THE STUDENT WILL BE ABLE TO ASSESS THE FEASIBILITY OF A SYNTHETIC PATH; TO SELECT THE BEST CONDITIONS FOR THE DEVELOPMENT OF A SYNTHETIC AND BIOSYNTHETIC PROCESS. COMMUNICATION SKILLS: THE STUDENT WILL BE ABLE TO REPRESENT AND COMMUNICATE, THROUGH TEXTS OR VIRTUAL TOOLS SUCH AS THE APPS USED DURING THE COURSE, THE RESULTS OF RESEARCH OR OWN PROCESSES CONCERNING ORGANIC CHEMICAL PROCESSES. ABILITY TO LEARN: THE STUDENT WILL BE ABLE TO USE TRADITIONAL BIBLIOGRAPHICAL TOOLS AND COMPUTER RESOURCES FOR ANALYSIS AND ARCHIVING; TO CARRY OUT RESEARCH ACTIVITIES, UNDERSTAND AND INTERPRET COMPLEX PUBLICITY TEXTS. |
| Prerequisites | |
|---|---|
| THE ACQUISITION OF THE OBJECTIVES RELATING TO THE FOLLOWING DISCIPLINES IS REQUIRED: PHYSICS, GENERAL AND INORGANIC CHEMISTRY, ORGANIC CHEMISTRY 1. IT IS ALSO REQUIRED GENERAL MATHEMATICS KNOWLEDGE |
| Contents | |
|---|---|
| PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN CLASSES OF DIFUNCTIONAL COMPOUNDS: DIOLS 0.5CFU; HYDROXYCARBONYL COMPOUNDS (HYDROXYALDEHYDES, HYDROXYCETONES AND HYDROXYACIDES) 0.5CFU; ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS 0.5CFU; DICARBONYL COMPOUNDS (DICARBOXYL ACIDS, BETA-KETOESTERS, BETA-DICHETONES) 0.5CFU;. MECHANISMS, PROCEDURES AND APPLICATION POTENTIALS OF THE MAIN CLASSES OF REACTIONS OF THE ANIONS ENOLATE 0.5CFU; AND ENAMINES 0.5CFU; PROPERTIES, REACTIVITY AND SYNTHETIC APPLICATIONS OF BETA-DICARBONYL COMPOUNDS AND, MORE GENERALLY, OF COMPOUNDS WITH ACTIVE METHYLENE GROUPS 0.5CFU; STRUCTURE AND REACTIVITY OF ALPHA, BETA-UNSATURATED CARBONYL COMPOUNDS V MECHANISMS AND SYNTHETIC APPLICATIONS OF THE AROMATIC NUCLEOPHILIC SUBSTITUTION REACTIONS 0.5CFU; STRUCTURE, PROPERTIES, METHODS OF SYNTHESIS AND REACTIVITY OF PHENOLS 0.5CFU; STRUCTURES, PROPERTIES AND REACTIVITY OF THE MAIN POLYCYCLIC AROMATIC COMPOUNDS 0.5CFU; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY 0.5CFU; OF ALIPHATIC AND AROMATIC AMINES 0.5CFU; AROMATIC DIAZONIUM SALTS AND THEIR METHOD OF USE IN THE ORGANIC SYNTHESIS,THE MOST COMMONLY USED STRATEGIES IN THE SYNTHESIS OF POLYSUBSTITUTED AROMATIC COMPOUNDS 0.5CFU; PROPERTIES, METHODS OF PREPARATION AND REACTIVITY OF THE MAIN AROMATIC HETEROCYCLIC SYSTEMS 0.5CFU;. PROPERTY, STEREOCHEMISTRY AND REACTIVITY OF MONOSACCHARIDES 0.5CFU; AND OF THE MAIN DEACCARIDES AND POLYSACCHARIDES 0.5CFU; AMINO ACIDS, PEPTIDES AND PROTEINS 0.5CFU;. LIPIDS. DANGEROUS REACTIONS 0.5CFU; |
| Teaching Methods | |
|---|---|
| THE TEACHING METHOD IS BASED ON THE FRONT LESSON (72H / 9 CFU) AND MAKES THE CONTRIBUTION OF PROJECTED SLIDES TO GUIDE THE TRAINING PATH AND THE ADOPTION OF TEXTS DEDICATED TO THE EXPLANATION OF THE TOPICS. AS PER TEACHING REGULATIONS, THE ATTENDANCE TO TEACHING MUST BE INTENDED AS COMPULSORY, THE METHODS OF CHECKING THE ATTENDANCE WILL BE COMMUNICATED TO THE STUDENTS BY THE TEACHERS; ANY ABSENCES THAT MAY HARM THE ACQUISITION OF THE INDICATED EDUCATIONAL OBJECTIVES MAY BE FILLED WITH CUSTOMIZED ACTIVITIES PREPARED BY THE TEACHING OWNERS. FACILITIES ARE GRANTED TO WORKING STUDENTS ACCORDING TO THE DIDACTIC REGULATION. |
| Verification of learning | |
|---|---|
| THE EXAM IS STRUCTURED IN A WRITTEN TEST AND IN AN ORAL TEST AND INCLUDES AN EVALUATION IN THIRTY-THIRTIES FOR BOTH. PASSING THE WRITTEN TEST WITH A SCORE OF AT LEAST 18/30 IS NECESSARY TO BE ABLE TO TAKE THE ORAL TEST AND OBTAIN THE FINAL MARK. DURING THE SEMESTER, TWO ONGOING TESTS WILL TAKE PLACE IN THE SAME WAY AS THE WRITTEN TASK EXPLAINED BELOW. THE ORIENTATION DATES ARE MID-APRIL AND EARLY JUNE. THE PASSING OF BOTH ONGOING TEST (SCORE OF AT LEAST 18/30) WILL ALLOW A DIRECT ADMISSION TO THE ORAL TEST. THE WRITTEN TEST CONSISTS OF THE ADMINISTRATION OF AN OPEN ANSWER QUESTIONNAIRE ON THE DIFFERENT TOPICS COVERED IN THE TEACHING PROGRAM, WHICH MUST BE COMPLETED WITHIN 120 MINUTES. THE WRITTEN TEST IS AIMED AT VERIFYING THE STUDENT'S ABILITY TO CORRECTLY APPLY THE KNOWLEDGE ACQUIRED IN THE COURSE TO A SERIES OF PRACTICAL PROBLEMS. IN GENERAL IN THE WRITTEN TEST THERE WILL BE 3 NOMENCLATURE QUESTIONS, 4-5 QUESTIONS CONCERNING THE PRODUCTS EXPECTED IN THE REACTIONS COVERED BY THE COURSE, 2 QUESTIONS ON ASPECTS RELATING TO TRANSFORMATION OF FUNCTIONAL GROUPS OR SYNTHETIC METHODOLOGIES ASPECTS OF THE COURSE, ONE SUBJECT OF THE COURSE AND AN OPEN ANSWERED QUESTION ON ONE OF THE TOPICS COVERED IN WHICH PARTICULAR APPLICATION ASPECTS MAY ALSO BE REQUIRED. THE ORAL TEST CONSISTS OF AN INTERVIEW OF 30/45 MINUTES THAT BEGINS WITH AN IN-DEPTH ANSWERS IN THE WRITTEN TEST (IF ANY) AND CONTINUES WITH TWO / THREE QUESTIONS AND RELATED DISCUSSION ON TOPICS DEVELOPED IN THE COURSE PROGRAM "AND DESCRIPTION CONTENTS OF THE COURSE ". THE COMBINATION OF THE TWO TESTS ALLOWS TO VERIFY THE LEVEL OF LEARNING KNOWLEDGE, THE CORRECT TERMINOLOGY, THE ABILITY TO ANALYSIS, WHICH SHOULD CONSTITUTE THE KNOWLEDGE ACQUIRED. THE EVALUATION TAKES INTO ACCOUNT TOTALLY OF: LEVEL OF KNOWLEDGE ACQUIRED; CAPACITY OF SYNTHESIS AND EXPOSURE; LANGUAGE APPROPRIATION; ABILITY TO ANALYSIS OF THE PROBLEMS AND TO APPLY THE ACQUIRED KNOWLEDGE. THE VERIFICATION METHODS ARE CONSIDERED ADEQUATE IN RELATION TO THE OBJECTIVES OF THE TEACHING, AND ALSO TO THE EXPECTED KNOWLEDGE AND SKILLS. THE FINAL SCORE CONSISTS OF THE WEIGHTED AVERAGE OF THE SCORES OF THE TWO TESTS, WITH GREATER INCIDENCE OF THE ORAL EXAM MARK AND WITH PARTICULAR REGARD TO EXPOSURE SKILLS, ANALYSIS OF THE PROBLEMS AND APPLICATION OF THE KNOWLEDGE ACQUIRED BY THE STUDENT |
| Texts | |
|---|---|
| A LIST OF MODERN TEXTS, WIDELY USED IN ITALIAN AND FOREIGN UNIVERSITIES IS SHOWN. HOWEVER, OTHER TEXTS ARE AVAILABLE THAT CAN PROVIDE THE NECESSARY ELEMENTS FOR STUDYING THE TOPICS DESCRIBED IN THE COURSE CONTENT. WE RECOMMEND THE USE OF TEXTS PUBLISHED IN THE LAST YEARS. B. BOTTA, ORGANIC CHEMISTRY, ED. EDI-ERMES, MILAN; P. Y. BRUICE, ORGANIC CHEMISTRY, ED. EDISES, NAPLES; J. G. SMITH, ORGANIC CHEMISTRY, ED. MCGRAW-HILL, MILAN; J. MCMURRY, ORGANIC CHEMISTRY, ED. PICCIN, PADUA |
| More Information | |
|---|---|
| THE COURSE IS TAUGHT IN ITALIAN THE ATTENDANCE IS MANDATORY LOCATION: DEPARTMENT OF PHARMACY |
BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-12-13]
