Stefania MARZOCCO | GENERAL AND MOLECULAR PHARMACOLOGY
Stefania MARZOCCO GENERAL AND MOLECULAR PHARMACOLOGY
cod. 0522100023
GENERAL AND MOLECULAR PHARMACOLOGY
| 0522100023 | |
| DIPARTIMENTO DI CHIMICA E BIOLOGIA "ADOLFO ZAMBELLI" | |
| ARCHIVE AND LIBRARY CONSERVATION AND MANAGEMENT | |
| 2015/2016 |
| OBBLIGATORIO | |
| YEAR OF COURSE 2 | |
| YEAR OF DIDACTIC SYSTEM 2009 | |
| SECONDO SEMESTRE |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| BIO/14 | 5 | 40 | LESSONS | |
| BIO/14 | 1 | 12 | LAB |
| Objectives | |
|---|---|
| • KNOWLEDGE AND UNDERSTANDING: THE STUDENT WILL ACQUIRE KNOWLEDGE OF THE PRINCIPLES OF PHARMACOLOGY ACQUIRING THE CONCEPT OF DRUG AS A MEANS FOR THE STUDY OF CELLULAR FUNCTION THROUGH ITS INTERACTION WITH THE MOLECULAR TARGET. ALSO ACQUIRE THE KNOWLEDGE ON DRUG DEVELOPMENT AND ON THE EFFECTS AND MECHANISMS OF ACTION OF DIFFERENT CLASSES OF DRUGS SUCH AS, FOR EXAMPLE, ANTI-INFLAMMATORY AND CHEMIOTERAPIC DRUGS. • APPLYING KNOWLEDGE AND UNDERSTANDING: THE COURSE PROVIDES THE ABILITY TO APPLY THE KNOWLEDGE IN THE FIELD OF PHARMACOLOGY IN THE BIO-ACTIVE COMPOUNDS USED IN THERAPY. • MAKING JUDGMENTS: THE ABILITY TO APPLY THE KNOWLEDGE ACQUIRED IN PRACTICE. THE KNOWLEDGE IMPARTED WILL COLLECT INFORMATION USEFUL IN THE CRITICAL EVALUATION OF THE EVOLUTION OF DRUG THERAPY. • COMMUNICATION SKILLS: THE ABILITY TO CLEARLY COMMUNICATE THEIR KNOWLEDGE AND JUDGMENT BOTH TO A SPECIALIST AND NOT OF ANY GRADE. • LEARNING SKILLS: THE OBTAINED KNOWLEDGE WILL BE A SOLID AND BROAD CULTURAL BASE TO ALLOW, ALSO MAKING USE OF ELECTRONIC DATABASES, NATIONAL AND INTERNATIONAL, A CONTINUOUS UPDATE NEED TO PRACTICE PHARMACY. |
| Prerequisites | |
|---|---|
| PREREQUISITES: FOR UNDERSTANDING OF THIS COURSE THE ACQUISITION OF BIOCHEMISTRY, GENERAL PHYSIOLOGY AND PATHOLOGY MECHANISMS’ ARE REQUIRED. |
| Contents | |
|---|---|
| ROUTES OF ADMINISTRATION, ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION OF DRUGS. MEANING OF MEDICATION. DRUG-RECEPTOR INTERACTION. AGONISTS, ANTAGONISTS, INVERSE AGONISTS. POTENCY AND EFFICACY OF A DRUG. THERAPEUTIC INDEX. COUPLED RECEPTOR AND ION CHANNEL DRUGS THAT MODULATE THE ACTIVITY. METABOTROPIC RECEPTOR AND DRUGS THAT MODULATE THE ACTIVITY. CONCEPT OF CYTOSOLIC RECEPTOR AND DRUGS THAT MODULATE THE ACTIVITY. CONCEPT OF RECEPTOR TYROSINE KINASE AND DRUGS THAT MODULATE THE ACTIVITY. BIOLOGICAL DRUGS. FEATURES OF THE MAIN CLASSES OF CHEMOTHERAPY AND ANTI-INFLAMMATORY DRUGS, AUTACOIDS. BIOLOGICAL LABORATORY EXERCISES ON SELECTED TOPICS OF THE COURSE. |
| Teaching Methods | |
|---|---|
| FRONTAL LESSONS |
| Verification of learning | |
|---|---|
| • ORAL TEST |
| Texts | |
|---|---|
| THERE ARE MANY TEXTS, BOTH ITALIAN AND FOREIGN, CAN PROVIDE AN EXTENT EQUIVALENT TO EACH OTHER ELEMENTS NECESSARY FOR THE STUDY OF THE TOPICS IN THE SYLLABUS. 1) PAOLETTI R., NICOSIA S., CLEMENTI F., G. FUMAGALLI, GENERAL AND MOLECULAR PHARMACOLOGY, UTET. 2) GOODMAN & GILMAN, THE PHARMACOLOGICAL BASIS OF THERAPY, X ITALIAN EDITION, FREEMAN. WE RECOMMEND THE USE OF TEXTS PUBLISHED IN RECENT YEARS. |
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