ANALISI DEI FARMACI I

Pietro CAMPIGLIA ANALISI DEI FARMACI I

0760100014
DIPARTIMENTO DI FARMACIA
CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 5 ANNI
PHARMACY
2014/2015

OBBLIGATORIO
YEAR OF COURSE 3
YEAR OF DIDACTIC SYSTEM 2010
PRIMO SEMESTRE
CFUHOURSACTIVITY
1080LESSONS
Objectives
THE STUDENT MUST SHOW AT THE END OF THE COURSE:
1) KNOWLEDGE AND UNDERSTANDING
LABORATORY EQUIPMENT AND ITS USE; METHODS OF INTERPRETATION, ANALYSIS AND PRESENTATION OF DATA; TYPES OF QUANTITATIVE ANALYSIS AND PRINCIPLES BASED ON; PRINCIPAL METHODS OF ANALYSIS WITH SPECIAL REFERENCE TO THOSE USED IN QC IN THE PHARMACEUTICAL, COSMETIC AND FOOD INDUSTRIES. PRINCIPAL TOOLS AND TECHNIQUES USED IN QUANTITATIVE MODERN ANALYTICAL.
2) APPLYING KNOWLEDGE AND UNDERSTANDING
ABILITY TO MAKE THE MAIN OPERATIONS (FILTRATION,TITRATION, ETC); ABILITY TO COLLECT, INTERPRET AND ANALYZE EXPERIMENTAL DATA; ABILITY TO CHOOSE AND APPLY THE MOST CORRECT METHOD FOR SOLVING ANALYTICAL PROBLEMS.
3) MAKING JUDGEMENTS
ABILITY TO CONNECT THE SKILLS LEARNED DURING THE COURSE OF THAT LEARNED IN OTHER CLASSES; ABILITY TO RAISE AND PROCESS SCIENTIFIC DATA AND MAKE REVIEW ON THE BASIS OF THE OBTAINED RESULTS
4) COMUNICATIONS SKILLS
KNOW HOW TO DESCRIBE THE TECHNIQUES AND METHODS LEARNED.

5) LEARNING SKILLS
ABILITY TO EXTEND THE BASIC SKILLS ACQUIRED, FOUND ON SCIENTIFIC TEXTS AND ELECTRONIC DATABASES, WITH SPECIAL REFERENCE TO THE EUROPEAN OFFICIAL PHARMACOPEIA.
Prerequisites
YOU MUST ACQUIRE THE OBJECTIVES CONCERNING THE FOLLOWING DISCIPLINES: GENERAL AND INORGANIC CHEMISTRY, PHYSICS, MATHEMATICS. MOREOVER, THEY ARE STRONGLY RECOMMENDED THE ACQUISITION OF THE OBJECTIVES OF ANALYTICAL CHEMISTRY.
Contents
SAFETY IN LABORATORIES. REGULATIONS. THE ITALIAN OFFICIAL PHARMACOPOEIA (F.U.). THE EUROPEAN PHARMACOPOEIA (E.P.) . SOLUBILITY. SOLUBILITY PRODUCT. PRECIPITATION AND REDISSOLUTION OF THE PRECIPITATES. COLLOIDAL PRECIPITATES. GLASSWARE AND ITS USE. ELECTRONIC SCALES. SCALE OF WORK. CONCENTRATION UNITS. NORMALITY, EQUIVALENT CALCULATIONS IN VOLUMETRIC ANALYSIS. ANALYSIS OF THE PH OF STRONG AND WEAK ACIDS AND BASES. CALCULATION OF PH OF POLYPROTIC ACIDS AND THEIR SALTS. TITRATION CURVES OF ACIDS AND BASES. THEORY OF INDICATORS. MAIN ACID-BASE INDICATORS AND THEIR USE. PRIMARY STANDARDS, THEIR CHARACTERISTICS AND THEIR USE. STANDARD SOLUTIONS OF ACIDS AND BASES USED IN VOLUMETRIC ANALYSIS. TITRATION CURVES OF PRECIPITATION. DETERMINATION OF HALIDES ACCORDING TO MOHR, VOLHARD, FAJANS AND GAY-LUSSAC. PREPARATION OF STANDARD SOLUTIONS USED IN PRECIPITIMETRIA. EXAMPLES OF DETERMINATIONS OF PRECIPITATION .DEFINITION AND USE OF THE STANDARD REDUCTION POTENTIAL. REDOX INDICATORS AND SPECIFIC INDICATORS. PERMANGANOMETRY. VOLUMES OF OXYGEN IN HYDROGEN PEROXIDE. IODIMETRY. IODOMETRY. CERIMETRY. COMPLEXOMETRIC.
Teaching Methods
LECTURES, CLASSROOM EXERCISES, PRACTICAL SINGLE SEAT IN THE LABORATORY
Verification of learning
ORAL EXAMINATION
Texts
SKOOG, WEST, HOLLER, CROUCH, FONDAMENTI DI CHIMICA ANALITICA, EDISES
KOLTHOFF, SANDELL, MEEHAN, BRUCKENSTEIN, ANALISI CHIMICA QUANTITATIVA, PICCIN.
WATSON, ANALISI FARMACEUTICA, EDISES
KELLNER, MERMER, OTTO, WIDMER, CHIMICA ANALITICA, EDISES
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