COMPLEMENTI DI CHIMICA FARMACEUTICA

Pietro CAMPIGLIA COMPLEMENTI DI CHIMICA FARMACEUTICA

0760100037
DIPARTIMENTO DI FARMACIA
CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 5 ANNI
PHARMACY
2014/2015

YEAR OF COURSE 5
YEAR OF DIDACTIC SYSTEM 2010
SECONDO SEMESTRE
CFUHOURSACTIVITY
540LESSONS
Objectives
THE STUDENT MUST SHOW AT THE END OF THE COURSE:
1) KNOWLEDGE AND UNDERSTANDING
ACQUISITION OF KNOWLEDGE ON COMBINATORIAL CHEMISTRY AND DEVELOPMENT OF RANDOM OR TARGETED LIBRARIES.. ABILITY 'TO APPLY THE PROTOCOLS OF SOLID PHASE SYNTHESIS IN PARALLEL AND LIQUID PHASE, DOMINO REACTIONS AND MULTICOMPONENT REACTIONS. KNOWLEDGE OF THE FOUNDATIONS OF DRUG DESIGN AND IDENTIFICATION AND OPTIMIZATION OF A LEAD COMPOUND. NEW FRONTIERS IN DRUG DEVELOPMENT.

2) APPLYING KNOWLEDGE AND UNDERSTANDING
FROM SPHERES THEORY AND METHODOLOGY TO THOSE MOST' PROFESSIONAL WITH POSSIBILITY 'OF OPERATIONS OPERATING AND FACE AND SOLVING APPLICATION PROBLEMS IN PARTICULAR THOSE RELATING TO THE SPECIFIC CLASS.

3) MAKING JUDGEMENTS
ABILITY TO CONNECT THE SKILLS LEARNED DURING THE COURSE OF THAT LEARNED IN OTHER CLASSES; ABILITY TO RAISE AND PROCESS SCIENTIFIC DATA RELATED TO YOUR SCOPE.

4) COMUNICATIONS SKILLS
ACQUISITION OF ABILITY TO COMMUNICATE KNOWLEDGE LEARNED DURING THE COURSE.

5) LEARNING SKILLS
ABILITY TO EXTEND THE BASIC SKILLS ACQUIRED, FOUND ON SCIENTIFIC TEXTS AND ELECTRONIC DATABASES.
Prerequisites
YOU MUST ACQUIRE THE OBJECTIVES CONCERNING THE FOLLOWING DISCIPLINES: OGANICA CHEMISTRY, PHARMACOLOGY, BIOCHEMISTRY AND MEDICINAL CHEMISTRY I AND II.
Contents
COMBINATORIAL CHEMISTRY AND DEVELOPMENT OF RANDOM OR TARGETED LIBRARIES
- SYNTHESIS IN PARALLEL SOLID PHASE OR IN LIQUID PHASE WITH THE AID OF POLYMERS (PASP).
- DOMINO REACTIONS. MULTICOMPONENT REACTIONS.
IDENTIFICATION OF OPTIMIZATION METHODS OF A "LEAD" COMPOUND.
FUNDAMENTALS OF DRUG DESIGN.
NEW FRONTIERS IN DRUG DEVELOPMENT: ANTICANCER, AGENRS ACTIVE ON CARDIOVASCULAR SYSTEM, FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
Teaching Methods
LECTURES
Verification of learning
ORAL EXAMINATION
Texts
. KURTI, B. CZAKÒ. STRATEGIC APPLICATION OF NAMED REACTIONS IN ORGANIC SYNTHESIS. ELSEVIER ACADEMIC PRESS.

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