Paola RUSSO | TECHNOLOGY AND FORMULATION OF HERBAL PRODUCTS

cod. 0712100051

TECHNOLOGY AND FORMULATION OF HERBAL PRODUCTS

	0712100051
	DIPARTIMENTO DI FARMACIA
	EQF6
	HERBAL SCIENCE
	2022/2023

PERCORSO COMUNE

	OBBLIGATORIO
	YEAR OF COURSE 3
	YEAR OF DIDACTIC SYSTEM 2020
	FULL ACADEMIC YEAR

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	TECNOLOGIA DEI PRODOTTI ERBORISTICI MODULO DI TECNOLOGIA E FORMULAZIONE DEI PRODOTTI ERBORISTICI
	CHIM/09	6	48	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	FORMULAZIONE E LEGISLAZIONE DEI PRODOTTI COSMETICI MODULO DI TECNOLOGIA E FORMULAZIONE DEI PRODOTTI ERBORISTICI
	CHIM/09	3	24	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	PAOLA RUSSO2 T Curriculum
	GIULIA AURIEMMA1 Curriculum

	Objectives
	THE AIM OF THE COURSE IS TO PROVIDE STUDENTS KNOWLEDGES AND METHODOLOGIES TO CORRECTLY PREPARE HERBAL HEALTH PRODUCTS, WITH PARTICULAR ATTENTION FOR THE DIFFERENT PROCESS PHASES, SUCH AS HERBAL MATERIAL PREPARATION, DOSAGE FORM PRODUCTION, CONTROL, AND LABELLING, EACH IN ACCORDANCE WITH CURRENT LEGISLATION. AIM OF THE COURSE IS ALSO TO IMPROVE KNOWLEDGE ON REGULATION AND MARKETING ASPECTS OF COSMETIC PRODUCTS, IMPROVE CHEMICAL AND TECHNOLOGICAL PROPERTIES ON COSMETIC RAW MATERIALS AND ON FINAL COSMETIC FORMULATION. THE STUDENT APPLYING THE ACQUIRED SKILLS WILL HAVE TO BE ABLE TO PREPARE AN HERBAL PREPARATION, TO PROVIDE INFORMATION SUCH AS THE FORMULATION STABILITY AND THE RULES FOR PREPARATION BY THIRD PARTIES. AT THE END OF THE COURSE, THE STUDENT WILL BE ALSO ABLE TO APPLY THE ACQUIRED KNOWLEDGE TO CORRECTLY SELECT AND SUGGEST A COSMETIC PRODUCT ON THE BASIS OF THE INGREDIENTS AND THE COSMETIC FORMULATION.

THE AIM OF THE COURSE IS TO PROVIDE STUDENTS KNOWLEDGES AND METHODOLOGIES TO CORRECTLY PREPARE HERBAL HEALTH PRODUCTS, WITH PARTICULAR ATTENTION FOR THE DIFFERENT PROCESS PHASES, SUCH AS HERBAL MATERIAL PREPARATION, DOSAGE FORM PRODUCTION, CONTROL, AND LABELLING, EACH IN ACCORDANCE WITH CURRENT LEGISLATION.
AIM OF THE COURSE IS ALSO TO IMPROVE KNOWLEDGE ON REGULATION AND MARKETING ASPECTS OF COSMETIC PRODUCTS, IMPROVE CHEMICAL AND TECHNOLOGICAL PROPERTIES ON COSMETIC RAW MATERIALS AND ON FINAL COSMETIC FORMULATION.

THE STUDENT APPLYING THE ACQUIRED SKILLS WILL HAVE TO BE ABLE TO PREPARE AN HERBAL PREPARATION, TO PROVIDE INFORMATION SUCH AS THE FORMULATION STABILITY AND THE RULES FOR PREPARATION BY THIRD PARTIES.
AT THE END OF THE COURSE, THE STUDENT WILL BE ALSO ABLE TO APPLY THE ACQUIRED KNOWLEDGE TO CORRECTLY SELECT AND SUGGEST A COSMETIC PRODUCT ON THE BASIS OF THE INGREDIENTS AND THE COSMETIC FORMULATION.

	Prerequisites
	STUDENTS MUST HAVE PASSED ALL THE EXAMS OF THE FIRST COURSE YEAR, AS REQUIRED BY THE DIDACTIC REGULATION.

	Contents
	THE COURSE ENTITLED "TECHNOLOGY AND FORMULATION OF HERBAL PRODUCTS" CONSISTS OF TWO INTEGRATED MODULES. SPECIFICALLY, THE FIRST MODULE: "TECHNOLOGY OF HERBAL PRODUCTS" INCLUDES THE FOLLOWING CONTENTS: 1. HERBAL HEALTH PRODUCTS (LECTURES: 4H) - CLASSIFICATION; CURRENT LEGISLATION; GOOD PREPARATION PRACTICES (GPPS_OFFICIAL PHARMACOPOEIA); GOOD MANUFACTURING PRACTICES (GMPS). - HERBAL PREPARATIONS (SHREDDED OR POWDERED PLANT MATERIALS, TINCTURES, EXTRACTS, ESSENTIAL OILS, SQUEEZED JUICES, EXUDATES) AND FORMULATION DEVELOPMENT. 2. BIOPHARMACEUTICAL ASPECTS OF DOSAGE FORM DESIGN (LECTURES: 4H) 3. SOLID DOSAGE FORMS (LECTURES: 12H + 4H LABORATORY EXERCISES) - POWDER PREPARATION AND UNITARY OPERATIONS (GRINDING, MIXING, GRANULATION, DRYING, AND COMPRESSION); FORMULATION AND PREPARATION OF: POWDERS, GRANULATES, TABLETS, COATED TABLETS (CONFETTI AND FILM-COATED TABLETS), CANDY TABLETS, CHEWABLE TABLETS AND CAPSULES. 4. LIQUID DOSAGE FORMS (LECTURES: 8H + 4H LABORATORY EXERCISES) - UNITARY OPERATIONS (DISSOLUTION AND FILTRATION); FORMULATION AND PREPARATION OF: SOLUTIONS (AQUEOUS, ALCOHOLIC, OILY, GLYCERIN SOLUTIONS), SYRUPS, ELIXIRS, DISPERSED SYSTEMS (COLLOIDAL SUSPENSIONS AND DISPERSIONS, FLOCCULATED AND DEFLOCCULATED SUSPENSIONS), EMULSIONS. 5. SEMI-SOLID DOSAGE FORMS FOR CUTANEOUS APPLICATION; RHEOLOGY, OINTMENTS, CREAMS, PASTES, AND GELS (LECTURE: 2H + 2H LABORATORY EXERCISES) 6. PRESSURIZED PREPARATIONS, AND SUPPOSITORIES (LECTURE: 2H) 7. DOSAGE FORM STABILITY (CHEMICAL, PHYSICAL AND MICROBIOLOGICAL) (LECTURE: 2H) 8. DOSAGE FORM PACKAGING (LECTURE: 2H) 8. THE CONCEPT OF “QUALITY” OF HERBAL PRODUCTS (LECTURE: 2H) THE SECOND MODULE “FORMULATION AND LEGISLATION OF COSMETIC PRODUCTS” INCLUDES THE FOLLOWING CONTENTS: 1. EUROPEAN REGULATION N. 1223/2009 ON COSMETIC PRODUCTS, INTERNATIONAL NOMENCLATURE OF COSMETIC INGREDIENTS, SAFETY ASSESSMENT, PRODUCT INFORMATION FILE (P.I.F.) AND NOTIFICATION (6 HOURS) 2. COMPOSITION AND MAIN FUNCTIONS OF THE SKIN. THE SKIN AS A SUPPORT FOR THE APPLICATION OF COSMETIC PRODUCTS: SKIN PERMEATION (2 HOURS). 3. FUNCTIONAL CLASSIFICATION AND DESCRIPTION OF COSMETIC RAW MATERIALS: LIPIDS, RHEOLOGICAL MODIFIERS, SURFACTANTS, ANTIMICROBIAL PRESERVATIVES, EMULSIFIERS (8 HOURS) 4. MAIN COSMETIC FORMS, PREPARATION TECHNIQUES AND STABILITY: SOLUTIONS (WATER, ALCOHOL, HYDROALCOLIC, GLYCERIC, HYDROGLYCERIC, OILY), GEL, TENSIOLITES, EMULSIONS (8 HOURS)

Contents

THE COURSE ENTITLED "TECHNOLOGY AND FORMULATION OF HERBAL PRODUCTS" CONSISTS OF TWO INTEGRATED MODULES.

SPECIFICALLY, THE FIRST MODULE: "TECHNOLOGY OF HERBAL PRODUCTS" INCLUDES THE FOLLOWING CONTENTS:
1. HERBAL HEALTH PRODUCTS (LECTURES: 4H)
- CLASSIFICATION; CURRENT LEGISLATION; GOOD PREPARATION PRACTICES (GPPS_OFFICIAL PHARMACOPOEIA); GOOD MANUFACTURING PRACTICES (GMPS).
- HERBAL PREPARATIONS (SHREDDED OR POWDERED PLANT MATERIALS, TINCTURES, EXTRACTS, ESSENTIAL OILS, SQUEEZED JUICES, EXUDATES) AND FORMULATION DEVELOPMENT.
2. BIOPHARMACEUTICAL ASPECTS OF DOSAGE FORM DESIGN (LECTURES: 4H)
3. SOLID DOSAGE FORMS (LECTURES: 12H + 4H LABORATORY EXERCISES)
- POWDER PREPARATION AND UNITARY OPERATIONS (GRINDING, MIXING, GRANULATION, DRYING, AND COMPRESSION); FORMULATION AND PREPARATION OF: POWDERS, GRANULATES, TABLETS, COATED TABLETS (CONFETTI AND FILM-COATED TABLETS), CANDY TABLETS, CHEWABLE TABLETS AND CAPSULES.
4. LIQUID DOSAGE FORMS (LECTURES: 8H + 4H LABORATORY EXERCISES)
- UNITARY OPERATIONS (DISSOLUTION AND FILTRATION); FORMULATION AND PREPARATION OF: SOLUTIONS (AQUEOUS, ALCOHOLIC, OILY, GLYCERIN SOLUTIONS), SYRUPS, ELIXIRS, DISPERSED SYSTEMS (COLLOIDAL SUSPENSIONS AND DISPERSIONS, FLOCCULATED AND DEFLOCCULATED SUSPENSIONS), EMULSIONS.
5. SEMI-SOLID DOSAGE FORMS FOR CUTANEOUS APPLICATION; RHEOLOGY, OINTMENTS, CREAMS, PASTES, AND GELS (LECTURE: 2H + 2H LABORATORY EXERCISES)
6. PRESSURIZED PREPARATIONS, AND SUPPOSITORIES (LECTURE: 2H)
7. DOSAGE FORM STABILITY (CHEMICAL, PHYSICAL AND MICROBIOLOGICAL) (LECTURE: 2H)
8. DOSAGE FORM PACKAGING (LECTURE: 2H)
8. THE CONCEPT OF “QUALITY” OF HERBAL PRODUCTS (LECTURE: 2H)

THE SECOND MODULE “FORMULATION AND LEGISLATION OF COSMETIC PRODUCTS” INCLUDES THE FOLLOWING CONTENTS:
1. EUROPEAN REGULATION N. 1223/2009 ON COSMETIC PRODUCTS, INTERNATIONAL NOMENCLATURE OF COSMETIC INGREDIENTS, SAFETY ASSESSMENT, PRODUCT INFORMATION FILE (P.I.F.) AND NOTIFICATION (6 HOURS)
2. COMPOSITION AND MAIN FUNCTIONS OF THE SKIN. THE SKIN AS A SUPPORT FOR THE APPLICATION OF COSMETIC PRODUCTS: SKIN PERMEATION (2 HOURS).
3. FUNCTIONAL CLASSIFICATION AND DESCRIPTION OF COSMETIC RAW MATERIALS: LIPIDS, RHEOLOGICAL MODIFIERS, SURFACTANTS, ANTIMICROBIAL PRESERVATIVES, EMULSIFIERS (8 HOURS)
4. MAIN COSMETIC FORMS, PREPARATION TECHNIQUES AND STABILITY: SOLUTIONS (WATER, ALCOHOL, HYDROALCOLIC, GLYCERIC, HYDROGLYCERIC, OILY), GEL, TENSIOLITES, EMULSIONS (8 HOURS)

	Teaching Methods
	THE 6 UFC MODULE (48 HOURS) IS BASED ON: LECTURES (38 HOURS) AS ABOVE DESCRIBED, PRACTICAL LABORATORY EXERCISES (10 HOURS) ON THE VARIOUS TOPICS MENTIONED, INTERACTION WITH THE TEACHER AND/OR WITH EXPERTS OF THIS SECTOR. THE 3 UFC MODULE (24 HOURS) IS BASED ON: LECTURES (24 HOURS) AS ABOVE DESCRIBED.

	Verification of learning
	THE ACHIEVEMENT OF COURSE OBJECTIVES AND LEARNING OUTCOMES OBJECTIVES WILL BE VERIFIED BY PRACTICAL LABORATORY TEST, AND BOTH A WRITTEN AND AN ORAL EXAM; THE EVALUATION WILL BE EXPRESSED IN THIRTIETHS. IN ORDER TO TAKE THE ORAL EXAM, IT IS NECESSARY TO PASS BOTH THE LABORATORY AND THE WRITTEN EXAM. THE FINAL MODULE MARK MUST BE OPPORTUNELY AVERAGED WITH THE MARK OF THE SECOND MODULE OF THIS COURSE. - THE PRACTICAL AS WELL AS THE WRITTEN TEST WILL BE CARRIED OUT AT THE END OF THE COURSE; THEY WILL BE AIMED AT EVALUATING KNOWLEDGE AND SKILLS ACQUIRED; THE LABORATOTY TEST WILL BE MAINLY FOCUSED ON THE APPLICATION OF THE GPPS FOR THE PREPARATION OF A HERBAL PRODUCT (PREPARATION METHOD, PH CONTROLS, COMPILATION OF THE PROCESSING SHEET, LABELING ETC.); THE WRITTEN EXAM WILL BE ARTICULATED INTO APPROXIMATELY 20 QUESTIONS (MAXIMUM DURATION: 90 MINUTES). - THE ORAL EXAM WILL BE AIMED AT EVALUATING THE THEORETICAL KNOWLEDGE, THE AUTONOMY OF ANALYSIS, THE ABILITY TO REWORK CONTENTS INTO THE CORRECT FORMAT FOR PROFESSIONAL USE. THE FINAL EVALUATION WILL BE OBTAINED AS THE MEDIUM OF EACH PARTIAL MARKS. THE MINIMUM MARKS (18/30) WILL BE ATTRIBUTED TO STUDENTS WITH A FRAGMENTARY KNOWLEDGE AND A LIMITED CAPACITY TO REWORK THE TREATED CONCEPTS. THE MAXIMUM MARKS (30/30) WILL BE ATTRIBUTED TO STUDENTS ABLE TO DEMONSTRATE A COMPLETE KNOWLEDGE OF THE METHODOLOGIES AND A NOTABLE ABILITY TO REWORK CONTENTS. THE PRIDE WILL BE ATTRIBUTED ONLY TO STUDENTS WITH A SIGNIFICANT MASTERY OF THE METHODOLOGIES, WITH A HIGH ABILITY TO REWORK THE ACQUIRED KNOWLEDGE.

Verification of learning

THE ACHIEVEMENT OF COURSE OBJECTIVES AND LEARNING OUTCOMES OBJECTIVES WILL BE VERIFIED BY PRACTICAL LABORATORY TEST, AND BOTH A WRITTEN AND AN ORAL EXAM; THE EVALUATION WILL BE EXPRESSED IN THIRTIETHS. IN ORDER TO TAKE THE ORAL EXAM, IT IS NECESSARY TO PASS BOTH THE LABORATORY AND THE WRITTEN EXAM. THE FINAL MODULE MARK MUST BE OPPORTUNELY AVERAGED WITH THE MARK OF THE SECOND MODULE OF THIS COURSE.

- THE PRACTICAL AS WELL AS THE WRITTEN TEST WILL BE CARRIED OUT AT THE END OF THE COURSE; THEY WILL BE AIMED AT EVALUATING KNOWLEDGE AND SKILLS ACQUIRED; THE LABORATOTY TEST WILL BE MAINLY FOCUSED ON THE APPLICATION OF THE GPPS FOR THE PREPARATION OF A HERBAL PRODUCT (PREPARATION METHOD, PH CONTROLS, COMPILATION OF THE PROCESSING SHEET, LABELING ETC.); THE WRITTEN EXAM WILL BE ARTICULATED INTO APPROXIMATELY 20 QUESTIONS (MAXIMUM DURATION: 90 MINUTES).
- THE ORAL EXAM WILL BE AIMED AT EVALUATING THE THEORETICAL KNOWLEDGE, THE AUTONOMY OF ANALYSIS, THE ABILITY TO REWORK CONTENTS INTO THE CORRECT FORMAT FOR PROFESSIONAL USE.

THE FINAL EVALUATION WILL BE OBTAINED AS THE MEDIUM OF EACH PARTIAL MARKS.

THE MINIMUM MARKS (18/30) WILL BE ATTRIBUTED TO STUDENTS WITH A FRAGMENTARY KNOWLEDGE AND A LIMITED CAPACITY TO REWORK THE TREATED CONCEPTS.
THE MAXIMUM MARKS (30/30) WILL BE ATTRIBUTED TO STUDENTS ABLE TO DEMONSTRATE A COMPLETE KNOWLEDGE OF THE METHODOLOGIES AND A NOTABLE ABILITY TO REWORK CONTENTS.
THE PRIDE WILL BE ATTRIBUTED ONLY TO STUDENTS WITH A SIGNIFICANT MASTERY OF THE METHODOLOGIES, WITH A HIGH ABILITY TO REWORK THE ACQUIRED KNOWLEDGE.

	Texts
	MANUALE DELLE PREPARAZIONI ERBORISTICHE, SECONDA EDIZIONE. LIBRO DI FRANCO BETTIOL E FRANCO FRANCESCO VINCIERI (MANUALE DELLE PREPARAZIONI ERBORISTICHE. FITOTERAPICI, FITOCOSMETICI, PRODOTTI ERBORISTICI, INTEGRATORI ALIMENTARI A BASE DI PIANTE – 18 MAGGIO 2017) PRINCIPI DI TECNOLOGIA FARMACEUTICA. PAOLO COLOMBO, FRANCO ALHAIQUE, CARLA CARAMELLA, BICE CONTI, ANDREA GAZZANIGA, ELENA VIDALE - SECONDA EDIZIONE. CASA EDITRICE AMBROSIANA. ZANICHELLI ITALIAN OFFICIAL PHARMACOPOEIA XII ED. AND NBP MATERIAL PROVIDED BY THE TEACHER

Texts

MANUALE DELLE PREPARAZIONI ERBORISTICHE, SECONDA EDIZIONE. LIBRO DI FRANCO BETTIOL E FRANCO FRANCESCO VINCIERI (MANUALE DELLE PREPARAZIONI ERBORISTICHE. FITOTERAPICI, FITOCOSMETICI, PRODOTTI ERBORISTICI, INTEGRATORI ALIMENTARI A BASE DI PIANTE – 18 MAGGIO 2017)
PRINCIPI DI TECNOLOGIA FARMACEUTICA. PAOLO COLOMBO, FRANCO ALHAIQUE, CARLA CARAMELLA, BICE CONTI, ANDREA GAZZANIGA, ELENA VIDALE - SECONDA EDIZIONE. CASA EDITRICE AMBROSIANA. ZANICHELLI
ITALIAN OFFICIAL PHARMACOPOEIA XII ED. AND NBP
MATERIAL PROVIDED BY THE TEACHER

	More Information
	ATTENDANCE: COMPULSORY LANGUAGE: ITALIAN PLACE: DEPARTMENT OF PHARMACY

BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-08-21]

Paola RUSSO | TECHNOLOGY AND FORMULATION OF HERBAL PRODUCTS