IMPIANTI DELL'INDUSTRIA FARMACEUTICA

Anna Angela BARBA IMPIANTI DELL'INDUSTRIA FARMACEUTICA

0760100051
DIPARTIMENTO DI FARMACIA
CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 5 ANNI
PHARMACY
2015/2016

YEAR OF DIDACTIC SYSTEM 2010
PRIMO SEMESTRE
CFUHOURSACTIVITY
540LESSONS
Objectives

DEFINITIONS

SI BASE AND SUPPLEMENTARY QUANTITIES AND UNITS. CLOSED AND OPEN SYSTEMS. STEADY STATE AND UNSTEADY STATE. PROCESS SCHEME AND PROCESS LAYOUT. UNICHIM NOMENCLATURE AND SYMBOLS. SERVICE FLUIDS. MASS AND ENERGY BALANCES. UNIT OPERATIONS MODELS.

HEAT EXCHANGE AND TYPICAL EQUIPMENT.

HEAT TRANSPORT PHENOMENA. HEAT-TRANSFER COEFFICIENTS. GENERAL DESIGN OF A HEAT EXCHANGE EQUIPMENT. ENERGY BALANCES.

CONCENTRATION BY SOLVENT EVAPORATION AND TYPICAL EQUIPMENT.

EVAPORATORS; SINGLE EFFECT, MULTIPLE EFFECTS. SATURATED STEAM TABLE OF. APPLICATION OF MASS AND ENERGY BALANCES.

DRYING AND TYPICAL EQUIPMENT.

MOISTURE CONTENT. DRYING METHODS. DETERMINATION OF MOIST AIR PROPERTIES. PSYCHROMETRIC CHARTS.

DISTILLATION AND TYPICAL EQUIPMENT.

. EQUILIBRIUM STAGE OPERATION. RAOULT AND DALTON LAWS. PHASE AND EQUILIBRIUM DIAGRAMS. FLASH DISTILLATION. CONTINUOUS DISTILLATION WITH REFLUX. APPLICATION OF MASS AND ENERGY BALANCES.

LEACHING AND EXTRACTION AND TYPICAL EQUIPMENT.

. EQUILIBRIUM STAGE OPERATION. PRINCIPLES OF EXTRACTION AND MAIN OPERATIVE PARAMETERS.

EQUIPMENT AND PROCESSES INVOLVING SOLID MATERIALS.

PROPERTIES OF GRANULAR SOLIDS. GRINDING EQUIPMENT. TRANSPORT EQUIPMENT. STORAGE OF SOLIDS. MIXING EQUIPMENT.

EQUIPMENT IN CHEMICAL REACTIONS.

CHEMICAL REACTIONS. RATES OF REACTION. CONTINUOUS AND BATCH PROCESSES. REACTORS FOR BATCH AND CONTINUOUS PROCESSES: STRUCTURAL CHARACTERISTICS, EXERCISE, MASS BALANCES. COMPARISON BETWEEN THE DIFFERENT TYPES OF REACTORS.
Prerequisites

BASIC KNOWLEDGE OF CHEMISTRY, PHYSICS AND MATHEMATICS.


BASIC KNOWLEDGE OF ENGLISH LANGUAGE TOO.

Contents
P>DEFINITIONS

SI BASE AND SUPPLEMENTARY QUANTITIES AND UNITS. CLOSED AND OPEN SYSTEMS. STEADY STATE AND UNSTEADY STATE. PROCESS SCHEME AND PROCESS LAYOUT. UNICHIM NOMENCLATURE AND SYMBOLS. SERVICE FLUIDS. MASS AND ENERGY BALANCES. UNIT OPERATIONS MODELS.

HEAT EXCHANGE AND TYPICAL EQUIPMENT.

HEAT TRANSPORT PHENOMENA. HEAT-TRANSFER COEFFICIENTS. GENERAL DESIGN OF A HEAT EXCHANGE EQUIPMENT. ENERGY BALANCES.

CONCENTRATION BY SOLVENT EVAPORATION AND TYPICAL EQUIPMENT.

EVAPORATORS; SINGLE EFFECT, MULTIPLE EFFECTS. SATURATED STEAM TABLE OF. APPLICATION OF MASS AND ENERGY BALANCES.

DRYING AND TYPICAL EQUIPMENT.

MOISTURE CONTENT. DRYING METHODS. DETERMINATION OF MOIST AIR PROPERTIES. PSYCHROMETRIC CHARTS.

DISTILLATION AND TYPICAL EQUIPMENT.

. EQUILIBRIUM STAGE OPERATION. RAOULT AND DALTON LAWS. PHASE AND EQUILIBRIUM DIAGRAMS. FLASH DISTILLATION. CONTINUOUS DISTILLATION WITH REFLUX. APPLICATION OF MASS AND ENERGY BALANCES.

LEACHING AND EXTRACTION AND TYPICAL EQUIPMENT.

. EQUILIBRIUM STAGE OPERATION. PRINCIPLES OF EXTRACTION AND MAIN OPERATIVE PARAMETERS.

EQUIPMENT AND PROCESSES INVOLVING SOLID MATERIALS.

PROPERTIES OF GRANULAR SOLIDS. GRINDING EQUIPMENT. TRANSPORT EQUIPMENT. STORAGE OF SOLIDS. MIXING EQUIPMENT.

EQUIPMENT IN CHEMICAL REACTIONS.

CHEMICAL REACTIONS. RATES OF REACTION. CONTINUOUS AND BATCH PROCESSES. REACTORS FOR BATCH AND CONTINUOUS PROCESSES: STRUCTURAL CHARACTERISTICS, EXERCISE, MASS BALANCES. COMPARISON BETWEEN THE DIFFERENT TYPES OF REACTORS
Teaching Methods
LECTURES.
Verification of learning
ORAL INTERVIEW.
Texts

A.S. FOUST ET AL., I PRINCIPI DELLE OPERAZIONI UNITARIE, CASA ED. AMBROSIANA, MILANO 1980.


L. FABRIS, S. RIGAMONTI, LA FABBRICAZIONE INDUSTRIALE DEI MEDICINALI, SOC. EDITRICE ESCULAPIO-BOLOGNA 2008


D. FRISO, M. NIERO, OPERAZIONI UNITARIE DELL’INGEGNERIA ALIMENTARE, CLEUP, PADOVA, 2010


PERRY’S CHEMICAL ENGINEERS’ HANDBOOK, 8TH EDITION, MCGRAW HILL, NEW YORK, 2008


W. MCCABE, J. SMITH, P. HARRIOT, UNIT OPERATION OF CHEMICAL ENGINEERING, MCGRAW HILL, NEW YORK, 1993


A.J. HICKEY, D. GANDERTON, PHARMACEUTICAL PROCESS ENGINEERING, MARCEL DEKKER INC., NEW YORK, 2001


O. LEVELSPIEL, INGEGNERIA DELLE REAZIONI CHIMICHE, CASA EDITRICE AMBROSIANA, MILANO, 1978


MATERIALE DIDATTICO DISTRIBUITO A LEZIONE


More Information

PLACE AND TIME OF DELIVERY.

THE COURSE IS DELIVERED AT THE DEPARTMENT OF PHARMACY; TIMETABLE AND CLASSROOM: HTTP://WWW.FARMACIA.UNISA.IT/DIDATTICA/INDEX.
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