Pia RAGNO | IMMUNOBIOLOGY
Pia RAGNO IMMUNOBIOLOGY
cod. 0522100034
IMMUNOBIOLOGY
| 0522100034 | |
| DEPARTMENT OF CHEMISTRY AND BIOLOGY "ADOLFO ZAMBELLI" | |
| EQF7 | |
| BIOLOGY | |
| 2024/2025 |
| OBBLIGATORIO | |
| YEAR OF COURSE 1 | |
| YEAR OF DIDACTIC SYSTEM 2022 | |
| SPRING SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| MED/04 | 5 | 40 | LESSONS | |
| MED/04 | 1 | 12 | EXERCISES |
| Objectives | |
|---|---|
| GENERAL AIMS: THE COURSE AIMS TO PROVIDE STUDENTS WITH BASIC KNOWLEDGE OF THE ORGANIZATION, FUNCTIONING AND ROLES OF THE IMMUNE SYSTEM. KNOWLEDGE AND UNDERSTANDING: STUDENTS WILL DEVELOPE AND EXPAND KNOWLEDGE AND UNDERSTANDING OF MECHANISMS REGULATING INNATE AND ADAPTIVE IMMUNE RESPONSE; MORPHOLOGIC AND FUNCTIONAL CHARACTERISTICS OF INVOLVED CELL TYPES AND THEIR DIFFERENTIATION AND ACTIVATION. ALSO, STUDENTS WILL EXPAND KNOWLEDGE AND UNDERSTANDING OF THE ROLE OF THE IMMUNE SYSTEM IN TISSUE TRANSPLANTATION AND IN THE ONCOLOGY FIELD. APPLICATION OF KNOWLEDGE AND UNDERSTANDING: STUDENTS WILL BE ABLE TO USE ACQUIRED KNOWLEDGE FOR UNDERSTANDING IMMUNOLOGIC ISSUES, INCLUDING CLINIC IMPLICATIONS IN TISSUE TRANSPLANTATION AND IN ONCOLOGY. AUTONOMY OF JUDGEMENT: STUDENTS MAY ACQUIRE THE ABILITY TO STUDY AND CRITICALLY EVALUATE ISSUES IN THE IMMUNOLOGIC FIELD, FOCUSING ON THE KEY PROCESSES AND RELATED CHALLENGES. COMMUNICATIONS SKILLS: STUDENTS MAY DEVELOPE THE ABILITY TO PRESENT ACQUIRED KNOWLEDGE IN A CLEAR AND COMPREHENSIVE MANNER AND WITH THE APPROPRIATE SCIENTIFIC LANGUAGE, AND TO DISCUSS MAIN ISSUES. LEARNING ABILITIES: STUDENTS MAY ACQUIRE TOOLS TO DEVELOPE LEARNING METHODOLOGIES THAT WILL ALLOW THEM TO AUTONOMOUSLY EXPAND AND UPDATE THEIR KNOWLEDGE, ALSO MAKING USE OF CONVENTIONAL BIBLIOGRAPHIC TOOLS, COMPUTER AIDS AND MULTIMEDIA MATERIAL. |
| Prerequisites | |
|---|---|
| Knowledge of biochemistry, molecular biology, cytology |
| Contents | |
|---|---|
| CELLULAR AND MOLECULAR MECHANISMS OF THE INNATE IMMUNE RESPONSE:MECHANICAL, CHEMICAL AND BIOLOGICAL BARRIERS; PHAGOCYTES; INNATE IMMUNITY RECEPTORS;CYTOKINES AND CHEMOKINES; INFLAMMATION; COMPLEMENT CASCADE;INTERFERONS; NK CELLS (8H). CELLULAR AND MOLECULAR MECHANISMS OF THE ADAPTIVE IMMUNE RESPONSE. ANTIGEN RECEPTORS. IMMUNOGLOBULIN:STRUCTURE, GENETICS, VARIABILITY, FUNCTIONS (2H). T CELL RECEPTOR: STRUCTURE, GENETICS, CD4 AND CD8 EXPRESSION (2H). MHC: STRUCTURE, FUNCTION, GENETICS. ANTIGEN PRESENTING CELLS. ANTIGEN PROCESSING AND PRESENTATION (2H). ANTIGEN RECEPTORS-DEPENDENT SIGNALLING (2 H). DEVELOPMENT AND MATURATION OF T AND B LYMPHOCYTES. MECHANISMS OF CENTRAL AND PERIPHERAL TOLERANCE (4H). ACTIVATION OF T AND B LYMPHOCYTES; T-DEPENDENT AND T-INDEPENDENT ANTIGENS. IMMUNOLOGICAL MEMORY (8H). IMMUNE EFFECTOR MECHANISMS: CD4+ T HELPER LYMPHOCYTES AND CD8+ CYTOTOXIC T LYMPHOCYTES; ANTIBODIES ACTIVITIES (4H). MODULATION OF THE IMMUNE RESPONSE; ALLOGRAFT REJECTION; MMUNOLOGY AND CANCER (8H). CLASSROOM EXERCISES (12H). |
| Teaching Methods | |
|---|---|
| The course consists in lectures (5CFU, 40 hs), and exercise (1CFU, 12 hs). Both lectures and exercise are held in the classroom and include the use of slides. Exercise consists in selection, presentation, and discussion of scientific papers. |
| Verification of learning | |
|---|---|
| The achievement of the objectives is assessed by a written examination, consisting in 4 questions on the course contents, to be answered within 90 min. The student will be evaluated on the basis of the level of knowledge acquired on the main arguments of the course and for the ability to expose them in a correct and complete manner. |
| Texts | |
|---|---|
| - C.A. JANEWAY , JR - P. TRAVERS - M. WALPORT - M.J. SHLOMCHIK, IMMUNOBIOLOGIA, PICCIN |
BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-11-29]
