Fabrizio DAL PIAZ | Curriculum

CURRENT POSITION:

Associate Professor in Biochemistry at the Department of Medicine and Surgery, University of Salerno.

STUDIES:

Degree in Chemistry achieved at the Faculty of Chemistry of the University “Federico II” of Naples, on 1997, vote 110/110 cum laude.

PhD in Chemistry received in 2002 from the University “Federico II” of Naples discussing a thesis entitled “Conformational analysis of protein and protein complexes”.

WORKING EXPERIENCES:

From 2019 Associate Professor in Biochemistry at the Department of Medicine and Surgery, University of Salerno

From 2016 to 2019 Assistant professor in Biochemistry at the Department of Medicine and Surgery of the University of Salerno

From 2006 to 2016 Assistant professor in Biochemistry at the Department of Pharmacy of the University of Salerno.

From 2004 to 2006 young researcher at the Department of Pharmacy of the University of Salerno to lead a project on metabolomics and proteomics of Salvia ssp plants.

From 2002 to 2004 scientific manager and researcher at the "Laboratory of bio-analytical mass spectrometry" into the Interdepartmental Biotechnology Research Centre at the University of Bologna.

In 2000 he was at the International Agency for Research on Cancer (IARC) of Lion (France) working with dr Marlin Friesen, to develop new methods to identify DNA polymorphisms by mass spectrometry.

RESEARCH:

prof. Dal Piaz boasts a remarkable expertise in the study of biological systems through multi-omics appracohes coupled with biophysic and biochemical assays. He is indeed skilled of proteomic, interactomics and metabolomics investigation strategy and has a good know how about spectrometric methods aimed to the investigation of molecular interactions (surface plasmon resonance and circular dicroism) and about classical biochemical methods for protein analysis.

prof. Dal Piaz research is focused on four main research topics:

-: Identification and structural analysis of proteins involved in pathological processes. These studies are realized both on purified proteins, by biochemical approaches coupled with mass spectrometry analytical techniques, or on complex samples (cell or tissue lysates), by proteomic investigation methods.

-: Structural and chemical characterization of microbial and vegetal nano vescichel through the use of mass spectrometry-based ‘omics’ approaches, combined with physical methods.

-: Qualitative and quantitative analysis of bioactive small molecules and their metabolites in biological fluids and tissues by chromatographic and mass spectrometrry approaches.

-: Study on the interaction between bioactive small molecules (drugs) and target proteins. This investigation is aimed on the identification of the molecular targets and off-targets of pharmacologically active compounds, and is generally performed by compound-centered proteomics approaches. Moreover, the obtained drug-protein (covalent or non-covalent) complexes are investigated in terms of their stoichiometry, thermodynamic stability, interaction regions and conformational changes induced on protein three-dimensional structure by drug binding.

GRANTED PROJECTS:

2025: Princiapl Inestigator of the project “Innovative health beneficial foods based on Chia mucilage” Awarded through a competitive public call for proposals subject to peer review by the Italian Ministry for the Research

2023-25: Princiapl Investigator of the project “Translational pharmacology against rare tumors: 14-3-3 protein interaction network modulators as novel class of anti-cancer drugs” Awarded through a competitive public call for proposals subject to peer review by the Italian Ministry for the Research.

2024: Scientific manager of the project “AVENA for food” Awarded through a competitive public call for proposals subject to peer review by Regione Campania, aimed at recovering oats as a source of fiber and nutrients

2019-21 Principal Investigator of the project, named NutriFruitIce, for the development of a new functional food, consisting of ice cream implemented by algal extracts, Awarded through a competitive public call for proposals subject to peer review by Regione Campania

2019: Principal Investigator of the project "Development of analytical methods aimed at predictivity immunogenicity and pharmacokinetics for new biotechnological products” funded by Merk Serono.

OTHER INFORMATION:

Patent holder for “Kit and method for detecting chemical contaminants on surfaces”; application number 102019000007227.

Patent holder No. 102021000019526 of July 22, 2021 for “14-3-3 PROTEIN MODULATORS AS ANTITUMOR AGENTS.”

Founder and partener in the University spin-off MATOX.

Founder and Partner in the University spin-off BRAVE.

BIBLIOMETRIC PARAMETERS (May 2026)

Number of papers on international peer-reviewed journals: 205

H index: 44

Total number of citations: 6016