Silvana MORELLO | IMMUNOPHARMACOLOGY
Silvana MORELLO IMMUNOPHARMACOLOGY
cod. 0760300025
IMMUNOPHARMACOLOGY
| 0760300025 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACY | |
| 2024/2025 |
| OBBLIGATORIO | |
| YEAR OF COURSE 4 | |
| YEAR OF DIDACTIC SYSTEM 2023 | |
| SPRING SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| BIO/14 | 6 | 48 | LESSONS |
| Objectives | |
|---|---|
| TTHE COURSE AIMS TO PROVIDE STUDENTS WITH BOTH PRECLINICAL AND CLINICAL NOTIONS RELATED TO IMMUNE-REGULATORY DRUGS AND THE RATIONAL BASIS ON THE CLINICAL USE OF THIS CLASS OF DRUGS. AT THE END OF THE COURSE THE STUDENT WILL KNOW: -MECHANISMS REGULATING THE IMMUNE RESPONSE; - MECHANISM OF ACTION, PHARMACOLOGICAL EFFECTS, ADVERSE REACTIONS AND THERAPEUTIC USES OF THE MAIN NON-SPECIFIC, SPECIFIC-ACTION IMMUNE-STIMULATING AGENTS, IMMUNE-STIMULATING MONOCLONAL ANTIBODIES AND VACCINES; -MECHANISM OF ACTION, PHARMACOKINETICS, SIDE EFFECTS, INTERACTIONS AND THERAPEUTIC USES OF IMMUNOSUPPRESSIVE DRUGS. AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO: -ANALYSE AND ADDRESS ISSUES RELATED TO THE USE, INTERACTIONS AND ADVERSE EVENTS OF IMMUNOREGULATORY DRUGS FOR THE SUSTAINABILITY OF IMMUNO-INFLAMMATORY-BASED DISEASE THERAPIES. |
| Prerequisites | |
|---|---|
| PREREQUISITES: THE STUDENT MUST POSSESS KNOWLEDGE OF THE FUNDAMENTAL CONCEPTS OF MOLECULAR BIOLOGY, AS WELL AS THE FUNDAMENTAL NOTIONS OF GENERAL PHARMACOLOGY, TO ADEQUATELY ADDRESS THE STUDY OF THE DISCIPLINE. REQUIRED FOUNDATION COURSES: GENERAL PATHOLOGY |
| Contents | |
|---|---|
| THE TEACHING COURSE INCLUDES 48 HOURS OF LESSONS (6 CREDITS) ON THE FOLLOWING TOPICS: - MECHANISMS REGULATING NATURAL AND SPECIFIC IMMUNE RESPONSES (6 HOURS). - CLASSIFICATION OF DRUGS FOR THE IMMUNE SYSTEM (1 HOUR) IMMUNOSUPPRESSIVE DRUGS: GENERAL ASPECTS AND PHARMACOKINETIC CHARACTERISTICS OF TRADITIONAL AND BIOTECHNOLOGICAL DRUGS (4 HOURS). - ANTI-PROLIFERATIVE IMMUNOSUPPRESSIVE DRUGS (2 HOURS) - IMMUNOPHYLLINE LIGANDS (2 HOURS) - CORTICOSTEROIDS (6 HOURS) - BIOTECHNOLOGICAL DRUGS: MABS AND FUSION PROTEINS AGAINST T OR B CELLS, ANTI-CYTOKINES, ANTI-MIGRATION DRUGS (6 HOURS) INTEGRATED VISION AND CLINICAL APPLICATIONS OF IMMUNOREGULATORY DRUGS IN THE TREATMENT OF: - -RHEUMATOID ARTHRITIS (2 HOURS) - - PSORIASIS (2 HOURS) - -MULTIPLE SCLEROSIS (2 HOURS) -ASTHMA AND CHRONIC INFLAMMATORY BOWEL DISEASE (CROHN’S DISEASE AND CU) (2 HOURS): IMMUNOSTIMULANT DRUGS - SYNTHETIC DRUGS (1 HOUR) - RECOMBINANT CYTOKINES (2 HOURS) - IMMUNOGLOBULINS AND COMPLEX, NON-SPECIFIC, SPECIFIC IMMUNOGLOBULIN PREPARATIONS AND IMMUNOSTIMULATING MONOCLONAL ANTIBODIES (2 HOURS); PASSIVE AND ACTIVE ANTI-TUMOR IMMUNOTHERAPY (4 HOURS) VACCINES (4 HOURS). |
| Teaching Methods | |
|---|---|
| THE COURSE CONSISTS OF LECTURES THAT TAKE PLACE IN THE CLASSROOM BY USING POWERPOINT PROJECTIONS. PARTICIPATION IN FRONTAL TEACHING IS MANDATORY AND ACCESS TO THE EXAM REQUIRES THE ATTENDANCE OF AT LEAST 80% OF THE HOURS OF LECTURES. THE FREQUENCY WILL BE VERIFIED USING THE EASYBADGE AUTOMATIC DETECTION SYSTEM PROVIDED BY THE UNIVERSITY. |
| Verification of learning | |
|---|---|
| THE ACHIEVEMENT OF THE OBJECTIVES IS CERTIFIED BY PASSING AN EXAMINATION WITH ASSESSMENT IN THIRTIETH. THE EXAM CONSISTS OF AN ORAL TEST, LASTING UP TO 30 MINUTES, WHICH CONSISTS OF AN INTERVIEW WITH QUESTIONS AND DISCUSSION ON THE THEORETICAL CONTENTS INDICATED IN THE TEACHING PROGRAM AND IS AIMED AT ASCERTAINING THE LEVEL OF KNOWLEDGE AND UNDERSTANDING ACHIEVED BY THE STUDENT, AND TO VERIFY THE EXPOSURE CAPACITY BY USING THE APPROPRIATE TERMINOLOGY AND THE ABILITY TO ORGANIZE THE TOPICS INDEPENDENTLY. THE SCORE OF THE ORAL EXAM IS AIMED AT EVALUATING THE THEORETICAL STUDY OF THE STUDENT. THE MINIMUM SCORE WILL BE ATTRIBUTED TO THE STUDENT SHOWING KNOWLEDGE ON THE FUNDAMENTALS OF DRUGS THAT CAN MODULATE THE IMMUNE AND INFLAMMATORY RESPONSES. THE PRAISE CAN BE AWARDED TO STUDENTS WHO WILL REACH THE MAXIMUM MARK OF 30/30 AND WILL PROVE TO BE ABLE TO INDEPENDENTLY APPLY KNOWLEDGE AND SKILLS ACQUIRED IN CONTEXTS OTHER THAN THOSE PROPOSED IN CLASS. |
| Texts | |
|---|---|
| -TRATTATO DI FARMACOLOGIA, IDELSON-GNOCCHI. TERZA EDIZIONE, 2016 -LE BASI FARMACOLOGICHE DELLA TERAPIA GOODMAN & GILMAN, ZANICHELLI, 13 ED., 2019 -FARMACI BIOTECNOLOGICI; CEA, 1 ED 2020 (ZANICHELLI).. -IMMUNOLOGIA CELLULARE E MOLECOLARE, EDRA, ED. 10, 2022 |
| More Information | |
|---|---|
| ITALIAN TEACHING AT THE DEPARTMENT OF PHARMACY |
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