GIUSEPPINA AMODIO | BIOCHEMICAL AND BIOLOGICAL SCIENCES
GIUSEPPINA AMODIO BIOCHEMICAL AND BIOLOGICAL SCIENCES
cod. 1012500003
BIOCHEMICAL AND BIOLOGICAL SCIENCES
| 1012500003 | |
| DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA" | |
| EQF6 | |
| IMAGING AND RADIOTHERAPY TECHNIQUES | |
| 2017/2018 |
| OBBLIGATORIO | |
| YEAR OF COURSE 1 | |
| YEAR OF DIDACTIC SYSTEM 2017 | |
| PRIMO SEMESTRE |
| SSD | CFU | HOURS | ACTIVITY | ||
|---|---|---|---|---|---|
| SCIENZE BIOCHIMICHE E BIOLOGICHE - MOD. BIOCHIMICA | |||||
| BIO/10 | 2 | 24 | LESSONS | ||
| SCIENZE BIOCHIMICHE E BIOLOGICHE - MOD. BIOCHIMICA CLINICA E BILOGIA MOLECOLARE | |||||
| BIO/12 | 2 | 24 | LESSONS | ||
| SCIENZE BIOCHIMICHE E BIOLOGICHE - MOD. BIOLOGIA APPLICATA | |||||
| BIO/13 | 2 | 24 | LESSONS | ||
| Objectives | |
|---|---|
| MAIN OBJECTIVE OF THIS COURSE IS TO GIVE THE STUDENT BASIC KNOWLEDGE OF APPLIED BIOLOGY, CLINIC BIOCHEMISTRY AND MOLECULAR BIOLOGY. IN ADDITION, ASPECTS RELATED TO THE DIAGNOSTIC MEDICAL IMAGING WILL BE ALSO DISCUSSED. |
| Prerequisites | |
|---|---|
| KNOWLEDGE OF BASIC INORGANIC AND ORGANIC CHEMISTRY AND PHISICS |
| Contents | |
|---|---|
| 1. STRUCTURE AND FUNCTION OF THE BIOLOGICAL MACROMOLECULES. 2. AMINOACIDS AND PEPTIDES. PROTEIN STRUCTURE. FIBROUS PROTEINS: THE PECULIAR STRUCTURE OF COLLAGEN. GLOBULAR PROTEINS: MIOGLOBIN AND HAEMOGLOBIN. ENZYMES AND BASICS OF ENZYME KINETICS. 3. BASICS OF BIOENERGETICS, ATP. CARBOHYDRATES CATABOLISM. GLYCOLISIS. KREBS CYCLE. THE ELECTRON TRANSPORT CHAIN AND THE OXIDATIVE PHOSPHORILATION. LIPIDS CATABOLISM. PROTEIN CATABOLISM. UREA CYCLE. THE CORRELATION AMONG THE DIFFERENT METABOLIC PATHWAYS. 4. GENERAL ASPECTS OF THE CLINICAL CHEMISTRY LABORATORY. 5. COLLECTING, PROCESSING AND STORAGE OF VARIOUS BIOLOGICAL SAMPLES. 6. REGULATION OF ACID-BASE EQUILIBRIUM AND ELECTROLYTE BALANCE. 7. RENAL FUNCTION AND URINE ANALYSIS. 8. ALTERATIONS IN CARBOHYDRATES AND LIPIDS METABOLISMS. 9. MARKERS OF CARDIAC DAMAGE. 10. TUMOR MARKERS. 11. MOLECULAR TECHNLOGIES IN CLINICAL DIAGNOSTIC: PCR AND REAL-TIME PCR, RFLP, HYBRIDIZATION TECHNIQUES, AUTOMATED ANALYZERS, METHODS FOR MUTATION SCREENING. 12. STRUCTURE AND FUNCTION OF CELL MEMBRANES-LIPID MEMBRANE PROPERTIES AND ROLE OF MEMBRANE PROTEINS IN THE MEMBRANE TRANSPORT 13. MITHOCONDRIA- ORGANIZATION OF CELL METABOLISM-CELLULAR RESPIRATION AND ATP BIOSYNTHESIS 14.ORGANIZATION OF GENOMIC DNA- BIOLOGICAL SIGNIFICANCE OF TRANSCRIPTION AND TRANSLATION-GENETIC CODE-MUTATIONS 15. ORGANIZATION AND FUNCTION OF CELLULAR COMPARTMENTS: PEROXYSOMES-ENDOPLASMIC RETICULUM -THE SECRETORY PATHWAY –THE GOLGI COMPLEX- EXOCYTOSIS-FUNCTIONS OF THE ENDOSOMAL COMPARTMENT – CYTOSKELETON. 16. CELL DIVISION AND REPRODUCTION. THE CELL CYCLE. MITOSIS. MEIOSIS. SEXUAL REPRODUCTION. FERTILIZATION. |
| Teaching Methods | |
|---|---|
| LECTURES MULTIPLE CHOICE TEST TO ASSESS VARIOUS LEVELS OF LEARNING |
| Verification of learning | |
|---|---|
| MULTIPLE CHOICE TEST AND ORAL EXAM |
| Texts | |
|---|---|
| ALBERTS ET.AL ESSENTIAL MOLECULAR BIOLOGY OF THE CELL. - CHAMPE PC. ET AL. ELEMENTS OF BIOCHEMISTRY. EDIZIONI ZANICHELLI - BERTOLDI M ET AL. CHEMISTRY AND BIOCHEMISTRY. EDIZIONI EDISES - SAMAJA ET AL. CHEMISTRY AND BIOCHEMISTRY. EDIZIONI PICCIN |
| More Information | |
|---|---|
| 75% ATTENDANCE OF CLASS LESSONS AND LABORATORY EXPERIENCE IS MANDATORY. |
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