Carmine SELLERI | Projects
Carmine SELLERI Projects
2 Funded projects
Filter
Active
In this translational study, we will investigate mechanisms of action of potential novel anti-MM agents in newly diagnosed MM patients or in who relapsed or were refractory to previous regimens, including those daratumumab-based regimens and those in maintenance therapy with lenalidomide. Understanding pathophysiology of relapse/refractory MM and mechanisms of action of new drugs will improve clin
| Department | Dipartimento di Medicina, Chirurgia e Odontoiatria “Scuola Medica Salernitana”/DIPMED | |
| Principal Investigator | SELLERI Carmine (Project Coordinator) | |
| Funding | University funds | |
| Funders | Università degli Studi di SALERNO | |
| Cost | 2.316,36 euro | |
| Project duration | 25 November 2024 - 25 November 2027 | |
| Detail |
In this study, we aim at investigating the impact of ruxolitinib on marrow fibrosis in MPNs using a well-established 3D in vitro model of BM niche mimicking cell-to-cell contacts and paracrine pathways intercurrent between stromal cells and BMMCs in normal and pathological hematopoiesis.Specific aims: 1. Establishment of a 3D in vitro co-culture model of myelofibrosis.2. Ruxolitinib effects on
| Department | Dipartimento di Medicina, Chirurgia e Odontoiatria “Scuola Medica Salernitana”/DIPMED | |
| Principal Investigator | SELLERI Carmine (Project Coordinator) | |
| Funding | University funds | |
| Cost | 3.505,26 euro | |
| Project duration | 31 July 2023 - 31 July 2026 | |
| Detail |
Data source U-GOV dal 1 Gennaio 2013
