Stefano PEPE | ONCOLOGY-HEMATOLOGY AND BLOOD DISEASES

cod. 1060100030

ONCOLOGY-HEMATOLOGY AND BLOOD DISEASES

	1060100030
	DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA"
	CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 6 ANNI
	MEDICINE AND SURGERY
	2014/2015

PERCORSO COMUNE Cohort 2011/2012

	OBBLIGATORIO
	YEAR OF COURSE 4
	YEAR OF DIDACTIC SYSTEM 2011
	SECONDO SEMESTRE

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - MOD 1
	MED/06	3	24	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - AFP
	MED/06	1	12	INTERNAL STAGE	VARIOUS EDUCATIONAL ACTIVITIES
3	ONCOLOGIA EMATO-ONCOLOGIA E MALATTIE DEL SANGUE - MOD 2
	MED/15	4	32	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
4	ONCOLOGIA EMATO-ONCOLOGIA E MALATTIE DEL SANGUE - MOD 4
	MED/15	1	12	INTERNAL STAGE	VARIOUS EDUCATIONAL ACTIVITIES

PROFESSORS

	CARMINE SELLERI42 T Curriculum
	STEFANO PEPE31 Curriculum

	Objectives
	THE COURSE IS DESIGNED TO PROVIDE THE KNOWLEDGE OF BASIC MECHANISMS INVOLVED IN THE MAIN HEMATOLOGIC MALIGNANCIES AND NON (INCLUDING HEMOSTASIS DISEASES) AS WELL AS OF THE MAIN SOLID CANCERS, COMBINING THE BASIC KNOWLEDGE AND INFORMATION ARISING FROM CLINICAL AND LABORATORY STUDIES, AND TO ALLOW THE ACQUISITION OF THE ELEMENTS NECESSARY FOR THE CORRECT DIAGNOSIS, STAGING, PROGNOSIS, MANAGEMENT AND THERAPEUTIC RESPONSE OF THESE DISEASES.

THE COURSE IS DESIGNED TO PROVIDE THE KNOWLEDGE OF BASIC MECHANISMS INVOLVED IN THE MAIN HEMATOLOGIC MALIGNANCIES AND NON (INCLUDING HEMOSTASIS DISEASES) AS WELL AS OF THE MAIN SOLID CANCERS, COMBINING THE BASIC KNOWLEDGE AND INFORMATION ARISING FROM CLINICAL AND LABORATORY STUDIES, AND TO ALLOW THE ACQUISITION OF THE ELEMENTS NECESSARY FOR THE CORRECT DIAGNOSIS, STAGING, PROGNOSIS, MANAGEMENT AND THERAPEUTIC RESPONSE OF THESE DISEASES.

	Prerequisites
	THE STUDENT MUST HAVE ALREADY ACQUIRED, THROUGH THE PREVIOUS COURSES, BIOLOGICAL CONCEPTS CONCERNING THE MECHANISMS OF NEOPLASTIC TRANSFORMATION OF HEMATOLOGIC MALIGNANCIES AND SOLID CANCERS. IN ADDITION, THE STUDENT MUST KNOW PATHOPHYSIOLOGY OF MAIN COAGULATION DISORDERS AND MECHANISMS OF ACTION OF ANTINEOPLASTIC DRUGS.

	Contents
	HEMATOLOGY COURSE WILL FOCUS ON EPIDEMIOLOGY, NATURAL HISTORY, DIAGNOSIS, STAGING, PROGNOSIS AND TREATMENT OF MOST COMMON NEOPLASTIC AND NON NEOPLASTIC HEMATOLOGICAL DISEASES, AS WELL AS OF HEMOSTASIS. HEMATOLOGY TOPICS: 1. IRON DEFICIENCY ANEMIA. 2. MEGALOBLASTIC ANEMIA 3. ENZYME DEFICIENCY ANEMIAS AND PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 4. HEMOLYTIC ANEMIAS 5. HEMOGLOBINOPATHIES (SICKLE CELL ANEMIA) 6. HEREDITARY SPHEROCYTOSIS 7. THALASSEMIA 8. APLASTIC ANEMIA 9. ACUTE LYMPHOID LEUKEMIA 10. ACUTE MYELOID LEUKEMIA 11. CHRONIC MYELOID LEUKEMIA 12. CHRONIC LYMPHOCYTIC LEUKEMIA 13. MYELOPROLIFERATIVE SYNDROMES (POLYCYTHEMIA, THROMBOCYTHEMIA, MYELOFIBROSIS, CHRONYC MYELOMONOCYTIC LEUKEMIA) 14. MYELODYSPLASTIC SYNDROMES 15.MULTIPLE MYELOMA AND OTHER IMMUNOPROLIFERATIVE SYNDROMES 16. HODGKIN LYMPHOMAS 17. NON-HODGKIN LYMPHOMA 18. THROMBOCYTOPENIA AND THROMBOCYTOPATHIES 19. HAEMORRHAGIC DISEASES 20. HAEMOPHILIA AND VON WILLEBRAND DISEASE 21. VENOUS AND ARTERIAL THROMBOEMBOLISM: PREVENTION AND TREATMENT 22. 23.MARROW TRANSPLANT. ONCOLOGY COURSE. GENERAL PRINCIPLES: BIOLOGY OF CANCER; TRANSFORMATION MECHANISMS OF CANCER; INVASION AND METASTASIS; EPIDEMIOLOGY PRINCIPLES OF CANCER (CANCER PREVENTION: PRIMARY AND SECONDARY PREVENTION, SCREENINGS AS WELL AS CHEMOPREVENTION); CLINICAL APPROACH TO THE PATIENT WITH CANCER (DIAGNOSIS, STAGING, PROGNOSTIC FACTORS, PREDICTIVE FACTORS AND THERAPEUTIC MANAGEMENT); PRINCIPLES OF ANTI-TUMOR THERAPY (THE ROLE OF RADIOTHERAPY,SURGERY AND MEDICAL TREATMENT); RATIONAL BASIS OF MEDICAL THERAPY OF CANCER (ADJUVANT THERAPY, NEOADJUVANT THERAPY, TREATMENT OF ADVANCED DISEASE,CHEMOTHERAPY, HORMONE THERAPY, NEW MOLECULAR DRUGS); SIDE EFFECTS OF DRUGS. PRINCIPLES OF SUPPORT THERAPY; METHODOLOGY PRINCIPLES IN CLINICAL ONCOLOGY. SPECIALISTIC PART: DIAGNOSIS, STAGING AND TREATMENT OF FOLLOWING SOLID CANCERS: BREAST CANCER; LUNG CANCER; GASTRO-INTESTINAL CANCER (ESOPHAGUS, STOMACH, PANCREAS, COLORECTAL); PROSTATE CANCER; OVARIAN CANCER; GERMINAL CANCER; KIDNEY CANCER; MELANOMA.

Contents

HEMATOLOGY COURSE WILL FOCUS ON EPIDEMIOLOGY, NATURAL HISTORY, DIAGNOSIS, STAGING, PROGNOSIS AND TREATMENT OF MOST COMMON NEOPLASTIC AND NON NEOPLASTIC HEMATOLOGICAL DISEASES, AS WELL AS OF HEMOSTASIS. HEMATOLOGY TOPICS: 1. IRON DEFICIENCY ANEMIA. 2. MEGALOBLASTIC ANEMIA 3. ENZYME DEFICIENCY ANEMIAS AND PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 4. HEMOLYTIC ANEMIAS 5. HEMOGLOBINOPATHIES (SICKLE CELL ANEMIA) 6. HEREDITARY SPHEROCYTOSIS 7. THALASSEMIA 8. APLASTIC ANEMIA 9. ACUTE LYMPHOID LEUKEMIA 10. ACUTE MYELOID LEUKEMIA 11. CHRONIC MYELOID LEUKEMIA 12. CHRONIC LYMPHOCYTIC LEUKEMIA 13. MYELOPROLIFERATIVE SYNDROMES (POLYCYTHEMIA, THROMBOCYTHEMIA, MYELOFIBROSIS, CHRONYC MYELOMONOCYTIC LEUKEMIA) 14. MYELODYSPLASTIC SYNDROMES 15.MULTIPLE MYELOMA AND OTHER IMMUNOPROLIFERATIVE SYNDROMES 16. HODGKIN LYMPHOMAS 17. NON-HODGKIN LYMPHOMA 18. THROMBOCYTOPENIA AND THROMBOCYTOPATHIES 19. HAEMORRHAGIC DISEASES 20. HAEMOPHILIA AND VON WILLEBRAND DISEASE 21. VENOUS AND ARTERIAL THROMBOEMBOLISM: PREVENTION AND TREATMENT 22. 23.MARROW TRANSPLANT.
ONCOLOGY COURSE. GENERAL PRINCIPLES: BIOLOGY OF CANCER; TRANSFORMATION MECHANISMS OF CANCER; INVASION AND METASTASIS; EPIDEMIOLOGY PRINCIPLES OF CANCER (CANCER PREVENTION: PRIMARY AND SECONDARY PREVENTION, SCREENINGS AS WELL AS CHEMOPREVENTION); CLINICAL APPROACH TO THE PATIENT WITH CANCER (DIAGNOSIS, STAGING, PROGNOSTIC FACTORS, PREDICTIVE FACTORS AND THERAPEUTIC MANAGEMENT); PRINCIPLES OF ANTI-TUMOR THERAPY (THE ROLE OF RADIOTHERAPY,SURGERY AND MEDICAL TREATMENT); RATIONAL BASIS OF MEDICAL THERAPY OF CANCER (ADJUVANT THERAPY, NEOADJUVANT THERAPY, TREATMENT OF ADVANCED DISEASE,CHEMOTHERAPY, HORMONE THERAPY, NEW MOLECULAR DRUGS); SIDE EFFECTS OF DRUGS. PRINCIPLES OF SUPPORT THERAPY; METHODOLOGY PRINCIPLES IN CLINICAL ONCOLOGY. SPECIALISTIC PART: DIAGNOSIS, STAGING AND TREATMENT OF FOLLOWING SOLID CANCERS: BREAST CANCER; LUNG CANCER; GASTRO-INTESTINAL CANCER (ESOPHAGUS, STOMACH, PANCREAS, COLORECTAL); PROSTATE CANCER; OVARIAN CANCER; GERMINAL CANCER; KIDNEY CANCER; MELANOMA.

	Teaching Methods
	COURSE WILL BE PERFORMED THROUGH LECTURES, DISCUSSION OF CLINICAL CASES , SEMINARS, MONOTHEMATIC COURSES, FAVOURING THE ACQUISITION BY THE STUDENTS OF THE NECESSARY KNOWLEDGE AND SKILLS IN THE HEMATOLOGY AND ONCOLOGY FIELDS

	Verification of learning
	WRITTEN AND ORAL EXAMINATION

	Texts
	NEAL S. YOUNG, STANTON L. GERSON, KATHERINE A HIGH. CLINICAL HEMATOLOGY. ELSEVIER, 2006. OXFORD TEXTBOOK OF ONCOLOGY, SECOND EDITION. OXFORD UNIVERSITY PRESS, 2001. PRINCIPLES AND PRACTICE OF ONCOLOGY. AUTORI: DEVITA, HELLMAN, AND ROSENBERG. LIPPINCOTT, 2011.

	More Information
	CARMINE SELLERI (PROFESSOR OF HEMATOLOGY); PEPE STEFANO (PROFESSOR OF ONCOLOGY)

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Stefano PEPE | ONCOLOGY-HEMATOLOGY AND BLOOD DISEASES