2. Professors
  3. PEPE Stefano
  4. Teaching

ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - AFP

Stefano PEPE ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - AFP

1060100074
DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA"
EQF7
MEDICINE AND SURGERY
2017/2018

OBBLIGATORIO
YEAR OF COURSE 4
YEAR OF DIDACTIC SYSTEM 2012
SECONDO SEMESTRE
CFUHOURSACTIVITY
1ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - AFP MOD ONCOLOGIA MEDICA
112INTERNAL STAGE
2ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - AFP MOD MALATTIE DEL SANGUE
112INTERNAL STAGE
CARMINE SELLERI2 T Curriculum
STEFANO PEPE1 Curriculum
Objectives
THE COURSE AIMS TO PROVIDE THE KNOWLEDGE OF THE PATHOGENETIC MECHANISMS ON THE MAIN HEMATOLOGICAL DISEASES AND SOLIDS TUMORS, INCLUDING BASIC KNOWLEDGE AND INFORMATION FROM THE CLINICAL AND LABORATORY STUDIES AS WELL AS TO ALLOW THE ACQUISITION OF DIAGNOSTIC ELEMENTS NECESSARY FOR THE STAGING, PROGNOSIS AND THERAPY OF THE ABOVE REPORTED DISEASES
Prerequisites
STUDENTS MUST HAVE ALREADY ACQUIRED THROUGH THE PREVIOUSCOURSES THE CONCEPTS OF GENERAL BIOLOGY CONCERNING MECHANISMS OF TUMOR EVOLUTION AND PATHOPHYSIOLOGY OF BOTH HEMATOLOGIC AND SOLID NEOPLASTIC DISEASES. THE STUDENT MUST KNOW THE PHYSIOPATHOLOGY OF THE MAIN HAEMOSTASIS DISEASES, AS WELL AS THE MECHANISM OF ACTION OF THE MOST IMPORTANT ANTINEOPLASTIC DRUGS.
Contents
COURSE OF ONCO-HEMATOLOGY AND BLOOD DISEASES:
1.IRON DEFICIENCY ANEMIA 2. MEGALOBLASTIC ANEMIA 3. RED BLOOD CELLS ENZYMOPATHIES. PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 4. AUTOIMMUNE HEMOLYTIC ANEMIAS 5. EMOGLOBINOPATIES 6. HEREDITARY SPHEROCYTOSIS 7. TALASSEMICAL SYNDROMES 8. BONE MARROW APLASIA 9. ACUTE LYMPHOBLASTIC LEUKEMIA 10. ACUTE MYELOID LEUKEMIA 11. CHRONIC MYELOID LEUKEMIA 12. CHRONIC LYMPHOBLASTIC LEUKEMIA 13. MYELOPROLIFERATIVE DISEASES: POLYCYTEMIA, THROMBOCYTEMIA, MYELOFIBROSIS,CHRONIC MYELOMONOCYTIC LEUKEMIA 14. MYELODYSPLASTIC SYNDROMES 15. MULTIPLE MYELOMA AND IMMUNOPROLYHERATIVE SYNDROMES 16.HODGKIN’S LYMPHOMA 17. NON-HODGKIN’S LYMPHOMA 18. THROMBOCYTOPENIA AND PLATELET DISFUNCTION 19.BLEEDING DISEASES 20.HEMOPHILIAS AND VON WILLEBRAND DISEASE 21. VENOUS AND ARTERIAL THROMBOSIS: PROPHYLAXIS AND THERAPY 22. HEMATOPOIETIC STEM CELL TRANSPLANTATION.

ONCOLOGY COURSE.
CANCER BIOLOGY: NEOPLASTIC TRANSFORMATION MECHANISMS, INVASION AND METASTASIS. CANCER EPIDEMIOLOGICY. PREVENTION OF NEOPLASIA: PRIMARY AND SECONDARY PREVENTION (SCREENINGS) AND CHEMIO-PREVENTION. CLINICAL APPROACH TO PATIENTS WITH NEOPLASIA: DIAGNOSIS, STAGING, PROGNOSTIC AND PREDICTIVE FACTORS, THERAPEUTIC PLANNING. ANTI-TUMORAL THERAPY: ROLE OF RADIOTHERAPY, SURGERY AND MEDICAL THERAPIES.
BASES OF NEOPLASTIC THERAPY: ADJUVANT THERAPY, NEOADJUVANT THERAPY, ADVANCED DISEASE THERAPY, CHEMOTHERAPY; HORMONE THERAPY; THERAPY WITH NEW MOLECULAR DRUG TARGETS; SIDE EFFECTS OF DRUGS; SUPPORTIVE THERAPY; CLINICAL METHODOLOGY IN ONCOLOGY. TREATMENTS OF THE FOLLOWING SOLID TUMORS: BREAST, LUNG, GASTRO-INTESTINAL (ESOPHAGUS, STOMACH, PANCREAS, COLORECTAL), PROSTATE; OVARY; GERMINALS; KIDNEY, MELANOMA.
Teaching Methods
THE COURSE WILL BE PERFORMED THROUGH FRONTAL LESSONS, DISCUSSION OF CLINICAL CASES AND SEMINARS, LECTURES, MONOTEMATIC COURSES AND THROUGH PROFESSIONAL FORMATIVE ACTIVITIES TO ALLOW THE STUDENTS TO ACQUIRE THE NECESSARY KNOWLEDGE AND THE CORRESPONDING EDUCATIONAL ABILITIES IN THE AREAS PROVIDED BY THE FORMATIVE PLAN
Verification of learning
WRITTEN AND ORAL
Texts
YOUNG S, GERSON S.L., HIGH K.A - CLINICAL HEMATOLOGY, MOSBY ELSEVIER. AMADORI G, EMATOLOGIA - LE BASI FISIOPATOLOGICHE MOLECOLARI E CLINICHE. EDITORE PICCIN, 2010. TURA S, LEZIONI DI EMATOLOGIA. EDITORE ESCULAPIO. VI EDIZIONE, 2011. CORE CURRICULUM. ONCOLOGIA CLINICA . AUTORI: BIANCO A.R., DE PLACIDO S., TORTORA G. MCGRAW-HILL COMPANIES (COLLANA MEDICINA), 2011
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