Stefano PEPE | HEMATOLOGY, ONCOHEMATOLOGY AND ONCOLOGY EXAM

cod. 1060100094

HEMATOLOGY, ONCOHEMATOLOGY AND ONCOLOGY EXAM

	1060100094
	DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA"
	EQF7
	MEDICINE AND SURGERY
	2018/2019

PERCORSO COMUNE Cohort 2015/2016

	OBBLIGATORIO
	YEAR OF COURSE 4
	YEAR OF DIDACTIC SYSTEM 2015
	SECONDO SEMESTRE

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - MOD ONCOLOGIA MEDICA
	MED/06	3	36	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - MOD MALATTIE DEL SANGUE
	MED/15	3	36	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	CARMINE SELLERI2 T Curriculum
	STEFANO PEPE1 Curriculum

	Objectives
	THE TRAINING COURSE HAS THE PURPOSE OF PROVIDING THE KNOWLEDGE OF THE PATHOGENETIC MECHANISMS OF THE MAIN NEOPLASTIC AND NON-NEOPLASTIC HEMATOLOGICAL DISEASES (INCLUDING HEMOSTASIS) AND OF THE PRINCIPAL SOLID NEOPLASTIC DISEASES, INTEGRATING THE BASIC KNOWLEDGE AND THE INFORMATION DERIVING FROM THE CLINICAL AND LABORATORY STUDIES, AS WELL AS TO ALLOW THE ACQUISITION OF THE ESSENTIAL DIAGNOSTIC ELEMENTS FOR THE CORRECT STAGING, PROGNOSIS, STRATEGY AND THERAPEUTIC RESPONSE OF THE ABOVE REPORTED PATHOLOGIES.

THE TRAINING COURSE HAS THE PURPOSE OF PROVIDING THE KNOWLEDGE OF THE PATHOGENETIC MECHANISMS OF THE MAIN NEOPLASTIC AND NON-NEOPLASTIC HEMATOLOGICAL DISEASES (INCLUDING HEMOSTASIS) AND OF THE PRINCIPAL SOLID NEOPLASTIC DISEASES, INTEGRATING THE BASIC KNOWLEDGE AND THE INFORMATION DERIVING FROM THE CLINICAL AND LABORATORY STUDIES, AS WELL AS TO ALLOW THE ACQUISITION OF THE ESSENTIAL DIAGNOSTIC ELEMENTS FOR THE CORRECT STAGING, PROGNOSIS, STRATEGY AND THERAPEUTIC RESPONSE OF THE ABOVE REPORTED PATHOLOGIES.

	Prerequisites
	THE STUDENT MUST ALREADY HAVE ACQUIRED, THROUGH THE PREVIOUS COURSES, THE NOTIONS OF BIOLOGY REGARDING THE GENERAL MECHANISMS OF THE NEOPLASTIC TRANSFORMATION AND THE PHYSIOPATHOLOGY OF THE TUMOR DISEASES, SUCH AS HEMATOLOGICAL DISEASES AND THE MOST IMPORTANT SOLID TUMORS. IN ADDITION, THE STUDENT SHOULD KNOW THE PHYSIOPATHOLOGY OF COAGULATION DISEASES, AS WELL AS THE MECHANISM OF ACTION OF THE MOST IMPORTANT CLASSES OF ANTINEOPLASTIC DRUGS.

Prerequisites

THE STUDENT MUST ALREADY HAVE ACQUIRED, THROUGH THE PREVIOUS COURSES, THE NOTIONS OF BIOLOGY REGARDING THE GENERAL MECHANISMS OF THE NEOPLASTIC TRANSFORMATION AND THE PHYSIOPATHOLOGY OF THE TUMOR DISEASES, SUCH AS HEMATOLOGICAL DISEASES AND THE MOST IMPORTANT SOLID TUMORS. IN ADDITION, THE STUDENT SHOULD KNOW THE PHYSIOPATHOLOGY OF COAGULATION DISEASES, AS WELL AS THE MECHANISM OF ACTION OF THE MOST IMPORTANT CLASSES OF ANTINEOPLASTIC DRUGS.

	Contents
	HEMATOLOGY: THE COURSE WILL FOCUS ON EPIDEMIOLOGY, NATURAL HISTORY, DIAGNOSIS, STAGING, PROGNOSIS AND PRINCIPLES OF THERAPY OF THE MOST COMMON NEOPLASTIC HEMATOLOGICAL DISEASES, AS WELL AS NON-NEOPLASTIC HEMATOLOGICAL DISEASES INCLUDING HEMOSTASIS. PROGRAM: IRON DEFICIENCY-ANEMIA MEGALOBLASTIC ANEMIA PAROXYSMAL NOCTURNAL HEMOGLOBINURIA IMMUNOLOGICAL HEMOLYTIC ANEMIA APLASTIC ANEMIAS SYCKLE CELL DISEASE SPHEROCYTOSIS HEMOGLOBIN DISEASES ENZYMOPATHIES THALASSEMIAS ACUTE AND CHRONIC MYELOID LEUKEMIAS ACUTE AND CHRONIC LYMPHOID LEUKEMIAS MYELODYSPLASTIC SYNDROMES CHRONIC MYELOPROLIFERATIVE DISEASES HODGKIN AND NON-HODGKIN LYMPHOMAS MULTIPLE MYELOMA THROMBOCYTOPENIAS HEMORRHAGIC DISEASES HEMOPHILIA A,B, VON WILLEBRAND DISEASE BONE MARROW TRANSPLANTATION ONCOLOGY: GENERAL PART PRINCIPLES OF BIOLOGY OF TUMORS: MECHANISMS OF NEOPLASTIC TRANSFORMATION, INVASION AND METASTASIS. PRINCIPLES OF EPIDEMIOLOGY OF TUMORS. TUMOR PREVENTION: PRIMARY PREVENTION, SECONDARY PREVENTION (SCREENINGS) AND CHEMOPREVENTION. CLINICAL APPROACH TO THE PATIENT WITH NEOPLASIA: DIAGNOSIS, STAGING, PROGNOSTIC FACTORS AND FACTORS. PRINCIPLES OF ANTI-TUMORAL THERAPY: ROLE OF RADIOTHERAPY, SURGERY AND MEDICAL THERAPIES. RATIONAL BASES OF THE MEDICAL THERAPY OF NEOPLASMS: ADAPTIVE THERAPY, NEOADJUVANT THERAPY, THERAPY OF ADVANCED DISEASE. CHEMOTHERAPY, HORMONE THERAPY, MOLECULAR TARGET DRUGS, SIDE EFFECTS, PRINCIPLES OF SUPPORT THERAPY. PRINCIPLES OF CLINICAL METHODOLOGY IN ONCOLOGY. SPECIAL PART DIAGNOSIS, STAGING AND TREATMENT OF THE FOLLOWING TUMORS: BREAST CANCER; LUNG CANCER; GASTRO-INTESTINAL CANCER (ESOPHAGUS, STOMACH, PANCREAS, COLON-RECT); PROSTATE CANCER; OVARIAN CANCER; GERMAN TUMORS; KIDNEY CANCER; MELANOMA.

Contents

HEMATOLOGY:
THE COURSE WILL FOCUS ON EPIDEMIOLOGY, NATURAL HISTORY, DIAGNOSIS, STAGING, PROGNOSIS AND PRINCIPLES OF THERAPY OF THE MOST COMMON NEOPLASTIC HEMATOLOGICAL DISEASES, AS WELL AS NON-NEOPLASTIC HEMATOLOGICAL DISEASES INCLUDING HEMOSTASIS.
PROGRAM:
IRON DEFICIENCY-ANEMIA
MEGALOBLASTIC ANEMIA
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA
IMMUNOLOGICAL HEMOLYTIC ANEMIA
APLASTIC ANEMIAS
SYCKLE CELL DISEASE
SPHEROCYTOSIS
HEMOGLOBIN DISEASES
ENZYMOPATHIES
THALASSEMIAS
ACUTE AND CHRONIC MYELOID LEUKEMIAS
ACUTE AND CHRONIC LYMPHOID LEUKEMIAS
MYELODYSPLASTIC SYNDROMES
CHRONIC MYELOPROLIFERATIVE DISEASES
HODGKIN AND NON-HODGKIN LYMPHOMAS
MULTIPLE MYELOMA
THROMBOCYTOPENIAS
HEMORRHAGIC DISEASES
HEMOPHILIA A,B,
VON WILLEBRAND DISEASE
BONE MARROW TRANSPLANTATION

ONCOLOGY:
GENERAL PART
PRINCIPLES OF BIOLOGY OF TUMORS: MECHANISMS OF NEOPLASTIC TRANSFORMATION, INVASION AND METASTASIS.
PRINCIPLES OF EPIDEMIOLOGY OF TUMORS.
TUMOR PREVENTION: PRIMARY PREVENTION, SECONDARY PREVENTION (SCREENINGS) AND CHEMOPREVENTION.
CLINICAL APPROACH TO THE PATIENT WITH NEOPLASIA: DIAGNOSIS, STAGING, PROGNOSTIC FACTORS AND FACTORS.
PRINCIPLES OF ANTI-TUMORAL THERAPY: ROLE OF RADIOTHERAPY, SURGERY AND MEDICAL THERAPIES.
RATIONAL BASES OF THE MEDICAL THERAPY OF NEOPLASMS: ADAPTIVE THERAPY, NEOADJUVANT THERAPY, THERAPY OF ADVANCED DISEASE.
CHEMOTHERAPY, HORMONE THERAPY, MOLECULAR TARGET DRUGS, SIDE EFFECTS,
PRINCIPLES OF SUPPORT THERAPY.
PRINCIPLES OF CLINICAL METHODOLOGY IN ONCOLOGY.

SPECIAL PART
DIAGNOSIS, STAGING AND TREATMENT OF THE FOLLOWING TUMORS:
BREAST CANCER;
LUNG CANCER;
GASTRO-INTESTINAL CANCER (ESOPHAGUS, STOMACH, PANCREAS, COLON-RECT);
PROSTATE CANCER;
OVARIAN CANCER;
GERMAN TUMORS;
KIDNEY CANCER;
MELANOMA.

	Teaching Methods
	THE COURSE WILL BE CARRIED OUT THROUGH FRONTAL, INTEGRATIVE (DISCUSSION OF CLINICAL CASES AND SEMINARS) AND ELECTIVE (MONOTHEMATIC COURSES) TEACHING.

	Verification of learning
	WRITE AND ORAL EXAMINATION.

	Texts
	AMADORI G, EMATOLOGIA - LE BASI FISIOPATOLOGICHE MOLECOLARI E CLINICHE. EDITORE PICCIN, 2010. TURA S, LEZIONI DI EMATOLOGIA. EDITORE ESCULAPIO. VI EDIZIONE, 2011. CORE CURRICULUM. ONCOLOGIA CLINICA . AUTORI: BIANCO A.R., DE PLACIDO S., TORTORA G. MCGRAW-HILL COMPANIES (COLLANA MEDICINA), 2011

	More Information
	NEAL S. YOUNG, STANTON L. GERSON, KATHERINE A HIGH. CLINICAL HEMATOLOGY. ELSEVIER, 2006. OXFORD TEXTBOOK OF ONCOLOGY, SECONDA EDIZIONE AUTORI: RL SOUHAMI, I TANNOCK, P HOHENBERGER AND J-C HORIOT. OXFORD UNIVERSITY PRESS, 2001. PRINCIPLES AND PRACTICE OF ONCOLOGY. AUTORI: DEVITA, HELLMAN, AND ROSENBERG. LIPPINCOTT, 2011.

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Stefano PEPE | HEMATOLOGY, ONCOHEMATOLOGY AND ONCOLOGY EXAM