Stefano PEPE | GYNECOLOGIC PATHOLOGY OF GLANDS

cod. 1012400020

GYNECOLOGIC PATHOLOGY OF GLANDS

	1012400020
	DEPARTMENT OF MEDICINE, SURGERY AND DENTISTRY "SALERNITANA MEDICAL SCHOOL"
	EQF6
	MIDWIFERY
	2024/2025

PERCORSO STUDY PATHWAY IN COMMON IN OBSTETRICS

	OBBLIGATORIO
	YEAR OF COURSE 2
	YEAR OF DIDACTIC SYSTEM 2013
	SPRING SEMESTER

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	PATOLOGIA GINECOLOGICA E DELLE GHIANDOLE ANNESSE - MOD. ONCOLOGIA MEDICA
	MED/06	2	24	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	PATOLOGIA GINECOLOGICA E DELLE GHIANDOLE ANNESSE - MOD. MEDICINA INTERNA
	MED/09	1	12	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
3	PATOLOGIA GINECOLOGICA E DELLE GHIANDOLE ANNESSE - MOD. CHIRURGIA PLASTICA
	MED/19	1	12	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
4	PATOLOGIA GINECOLOGICA E DELLE GHIANDOLE ANNESSE - MOD. FARMACOLOGIA
	BIO/14	1	12	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
5	PATOLOGIA GINECOLOGICA E DELLE GHIANDOLE ANNESSE - MOD. SCIENZE INFERMIERISTICHE OSTETRICO-GINECOLOGICHE
	MED/47	2	24	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	STEFANO PEPE1 T Curriculum
	MARTA MARRACINO2 Curriculum
	SERGIO BRONGO3 Curriculum
	VALERIA CONTI4 Curriculum
	-5

	Objectives
	The student will acquire a solid understanding of the main gynecological pathologies, with particular focus on the following areas: Biological and molecular mechanisms underlying gynecological cancers. Plastic surgery techniques used for the reconstruction of genitalia following gynecological surgeries. Main medications used in the treatment of gynecological pathologies. Medical-internistic approach in the assessment and management of patients. This training will provide the student with comprehensive preparation to understand and address gynecological issues in an integrated manner, combining theoretical, technical, and practical knowledge. KNOWLEDGE AND UNDERSTANDING By the end of the course, students will be able to identify and understand the health determinants, risk factors, and prevention strategies applied to the promotion and support of women's health, including that of pregnant women, women in labor, postpartum women, and newborns. ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING By the end of the course, students will have gained increasing independence in decision-making and implementing diagnostic-therapeutic procedures aimed at the health of women, newborns, and couples, working in healthcare teams, and at various levels of care intensity. Students will be able to apply the theoretical knowledge from Midwifery care-education, behavioral and social biological sciences to recognize the health needs of women in different reproductive life stages, the couple, within their social context, and newborns up to the first year of life. They will also be able to participate in the development and implementation of early oncological prevention and diagnostic programs in gynecology, as well as the organization of health education and promotion interventions, with particular focus on sexually transmitted diseases and promoting the adoption of adequate lifestyles. JUDGMENT AUTONOMY By the end of the course, students will be able to make responsible professional decisions during various phases of the healthcare process, assess their effectiveness, and proceed with decision re-planning, prioritizing patient care while considering legal, political, geographical, economic, ethical, and social influences. Additionally, students will learn to critically evaluate the outcomes of healthcare decisions based on patient outcomes and healthcare standards, and make decisions using a scientific approach to problem-solving, including evaluating the results of available scientific studies. COMMUNICATIVE SKILLS By the end of the course, students will have developed the skills to conduct interpersonal interviews with patients of all ages and their families within the healthcare process and/or with other healthcare professionals, conducting effective and methodical negotiations. Students will be able to support and encourage healthcare service users toward health choices, reinforcing coping skills, self-esteem, and enhancing available resources. Students will also use teaching and learning principles for specific informational or educational interventions directed at individual users, families, groups, and other professionals such as support staff, midwifery students, and nursing students, applying clear and organized communication of their mental synthesis. Finally, they will manage conflicts arising from differing positions, negotiating solutions and communicating effectively with the care team to agree on operational methods and implement and develop protocols and guidelines. LEARNING SKILLS By the end of the course, students should: develop independent study skills and be able to continuously assess their educational needs in relation to the nature and complexity of the problems to be addressed and the strategies to be managed; demonstrate the ability to cultivate doubts and tolerate uncertainties arising from study and practical activities; develop the ability to question their practice, considering timing, locations, and interlocutors; demonstrate the ability to continuously seek opportunities for self-learning, collaborative learning, and self-assessment within work teams.

The student will acquire a solid understanding of the main gynecological pathologies, with particular focus on the following areas:

Biological and molecular mechanisms underlying gynecological cancers.
Plastic surgery techniques used for the reconstruction of genitalia following gynecological surgeries.
Main medications used in the treatment of gynecological pathologies.
Medical-internistic approach in the assessment and management of patients.
This training will provide the student with comprehensive preparation to understand and address gynecological issues in an integrated manner, combining theoretical, technical, and practical knowledge.
KNOWLEDGE AND UNDERSTANDING

By the end of the course, students will be able to identify and understand the health determinants, risk factors, and prevention strategies applied to the promotion and support of women's health, including that of pregnant women, women in labor, postpartum women, and newborns.

ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING

By the end of the course, students will have gained increasing independence in decision-making and implementing diagnostic-therapeutic procedures aimed at the health of women, newborns, and couples, working in healthcare teams, and at various levels of care intensity.

Students will be able to apply the theoretical knowledge from Midwifery care-education, behavioral and social biological sciences to recognize the health needs of women in different reproductive life stages, the couple, within their social context, and newborns up to the first year of life.

They will also be able to participate in the development and implementation of early oncological prevention and diagnostic programs in gynecology, as well as the organization of health education and promotion interventions, with particular focus on sexually transmitted diseases and promoting the adoption of adequate lifestyles.

JUDGMENT AUTONOMY

By the end of the course, students will be able to make responsible professional decisions during various phases of the healthcare process, assess their effectiveness, and proceed with decision re-planning, prioritizing patient care while considering legal, political, geographical, economic, ethical, and social influences. Additionally, students will learn to critically evaluate the outcomes of healthcare decisions based on patient outcomes and healthcare standards, and make decisions using a scientific approach to problem-solving, including evaluating the results of available scientific studies.

COMMUNICATIVE SKILLS

By the end of the course, students will have developed the skills to conduct interpersonal interviews with patients of all ages and their families within the healthcare process and/or with other healthcare professionals, conducting effective and methodical negotiations. Students will be able to support and encourage healthcare service users toward health choices, reinforcing coping skills, self-esteem, and enhancing available resources.

Students will also use teaching and learning principles for specific informational or educational interventions directed at individual users, families, groups, and other professionals such as support staff, midwifery students, and nursing students, applying clear and organized communication of their mental synthesis. Finally, they will manage conflicts arising from differing positions, negotiating solutions and communicating effectively with the care team to agree on operational methods and implement and develop protocols and guidelines.

LEARNING SKILLS

By the end of the course, students should: develop independent study skills and be able to continuously assess their educational needs in relation to the nature and complexity of the problems to be addressed and the strategies to be managed; demonstrate the ability to cultivate doubts and tolerate uncertainties arising from study and practical activities; develop the ability to question their practice, considering timing, locations, and interlocutors; demonstrate the ability to continuously seek opportunities for self-learning, collaborative learning, and self-assessment within work teams.

	Prerequisites
	NONE

	Contents
	The course is divided into five modules: Medical Oncology Nursing Sciences Internal Medicine Pharmacology Plastic Surgery Medical Oncology Module (MED/06, 2 CFU, 24 hours) Principles of Oncology: epidemiology, primary and secondary prevention, neoplastic transformation (3 hours). Concepts of proliferative genetics, cytotoxic logarithmic effects, medical oncology principles (diagnosis, staging, and treatment) (3 hours). Cancer pain and pain management in the terminal phase: definition and types of pain, causes in cancer patients, pain assessment and treatments (3 hours). Importance of early diagnosis: tumor differentiation grade, clinical-therapeutic strategies for cancer treatment, screening, and early diagnosis (3 hours). Epidemiology and prevention of cancer (3 hours). Group work and multidisciplinary approach: GOM and PDTA (3 hours). Gynecological cancers: risk factors, epidemiology, prevention, diagnosis, and treatment (3 hours). Breast cancer: risk factors, epidemiology, prevention, diagnosis, and treatment (3 hours). Nursing Sciences Module (MED/47, 2 CFU, 24 hours) Mullerian anomalies: embryology, etiopathogenesis, classification, diagnostic ultrasound, and clinical diagnosis (2 hours). Menstrual cycle disorders: abnormal uterine bleeding, diagnosis, treatment, and medical and surgical therapy. Molar pregnancy: symptoms, diagnosis, staging, and treatment (3 hours). Genital tumors: ovarian and cervical, diagnosis, staging, and treatment. Endometriosis: definition, histology, incidence, risk factors, symptoms, diagnosis, and treatment. Postpartum endometritis: definition, symptoms, diagnosis, treatment, and prevention (3 hours). Diagnosis, treatment, and therapy for pelvic inflammatory disease, cervicitis, and acute salpingitis (2 hours). Amenorrhea: definition, classification, diagnosis, causes, and treatments (2 hours). Importance of perineal care in the postpartum period: pelvic floor definition, risk factors for pelvic floor dysfunction, perineal care with different scoring systems (3 hours). Hysterosalpingography: what it is, how it is performed, and when it is contraindicated. Operative hysteroscopy: instruments, indications, and execution techniques (3 hours). Pathologies of the uterine body: diagnosis, symptoms, and treatment of endometrial polyps, endometrial hyperplasia, uterine fibroids, uterine adenomyosis (3 hours). Breast gland pathology and the role of midwives in prevention (3 hours). Internal Medicine Module (MED/09, 1 CFU, 12 hours) Gender Medicine: definition and objectives (1 hour). The Immune System: innate and adaptive immunity, humoral and cellular immunity. Introduction to autoimmune diseases (3 hours). Laboratory work in rheumatic diseases, connective tissue diseases (General overview). Raynaud's phenomenon, Lupus, Rheumatoid Arthritis, Scleroderma, Antiphospholipid syndrome, Celiac disease (4 hours). Congenital and acquired immunodeficiencies (2 hours). Thrombotic Microangiopathies: thrombotic thrombocytopenic purpura (2 hours). Plastic Surgery Module (MED/19, 1 CFU, 12 hours) Anatomy of the skin and its appendages. Wound healing: normal and pathological healing (hypertrophic scars, keloids, ulcers, pressure sores). Skin grafts: definition, classification, and stages of grafting. Flaps: definition, classification, and indications (3 hours). Burns: definition, staging, clinical classification, lesions, and therapy/treatment in adults and children. Precancerous lesions and skin cancers (basal cell carcinoma, squamous cell carcinoma, melanomas): characteristics, definitions, classification, diagnosis, and prevention (3 hours). Genital transformation: diagnosis and treatment of gender dysphoria, fallopoiesis, and edoiopoiesis. Post-mastectomy breast reconstruction: reconstruction techniques and aesthetic breast augmentation. Vulvovaginal surgery: pelvic-perineal superficial reconstruction, malformations, and genitourinary syndromes (imperforate hymen, vaginal agenesis, vulvovaginal atrophy) (3 hours). Hypertrophy, asymmetry, and hypoplasia of the breasts. Malformations: hypospadias, epispadias, cleft lip and palate, polydactyly, syndactyly. Pressure ulcers (3 hours). Pharmacology Module (BIO/14, 1 CFU, 12 hours) Introduction to Pharmacology: general concepts of pharmacological action, drug origins, preclinical and clinical trials (2 hours). Pharmacokinetics (ADME): routes of drug administration, absorption, and distribution (2 hours). Pharmacokinetics (ADME): metabolism and elimination, pharmacokinetic parameters (2 hours). Pharmacodynamics: drug-receptor interaction, mechanisms of action, channel and metabotropic receptors, tyrosine kinase receptors, and intracellular receptors (3 hours). Pharmacological interactions, adverse drug reactions, and pharmacovigilance, introduction to pharmacogenetics (3 hours).

Contents

The course is divided into five modules:

Medical Oncology
Nursing Sciences
Internal Medicine
Pharmacology
Plastic Surgery
Medical Oncology Module (MED/06, 2 CFU, 24 hours)

Principles of Oncology: epidemiology, primary and secondary prevention, neoplastic transformation (3 hours).
Concepts of proliferative genetics, cytotoxic logarithmic effects, medical oncology principles (diagnosis, staging, and treatment) (3 hours).
Cancer pain and pain management in the terminal phase: definition and types of pain, causes in cancer patients, pain assessment and treatments (3 hours).
Importance of early diagnosis: tumor differentiation grade, clinical-therapeutic strategies for cancer treatment, screening, and early diagnosis (3 hours).
Epidemiology and prevention of cancer (3 hours).
Group work and multidisciplinary approach: GOM and PDTA (3 hours).
Gynecological cancers: risk factors, epidemiology, prevention, diagnosis, and treatment (3 hours).
Breast cancer: risk factors, epidemiology, prevention, diagnosis, and treatment (3 hours).
Nursing Sciences Module (MED/47, 2 CFU, 24 hours)

Mullerian anomalies: embryology, etiopathogenesis, classification, diagnostic ultrasound, and clinical diagnosis (2 hours).
Menstrual cycle disorders: abnormal uterine bleeding, diagnosis, treatment, and medical and surgical therapy. Molar pregnancy: symptoms, diagnosis, staging, and treatment (3 hours).
Genital tumors: ovarian and cervical, diagnosis, staging, and treatment. Endometriosis: definition, histology, incidence, risk factors, symptoms, diagnosis, and treatment. Postpartum endometritis: definition, symptoms, diagnosis, treatment, and prevention (3 hours).
Diagnosis, treatment, and therapy for pelvic inflammatory disease, cervicitis, and acute salpingitis (2 hours).
Amenorrhea: definition, classification, diagnosis, causes, and treatments (2 hours). Importance of perineal care in the postpartum period: pelvic floor definition, risk factors for pelvic floor dysfunction, perineal care with different scoring systems (3 hours).
Hysterosalpingography: what it is, how it is performed, and when it is contraindicated.
Operative hysteroscopy: instruments, indications, and execution techniques (3 hours).
Pathologies of the uterine body: diagnosis, symptoms, and treatment of endometrial polyps, endometrial hyperplasia, uterine fibroids, uterine adenomyosis (3 hours).
Breast gland pathology and the role of midwives in prevention (3 hours).
Internal Medicine Module (MED/09, 1 CFU, 12 hours)

Gender Medicine: definition and objectives (1 hour).
The Immune System: innate and adaptive immunity, humoral and cellular immunity. Introduction to autoimmune diseases (3 hours).
Laboratory work in rheumatic diseases, connective tissue diseases (General overview). Raynaud's phenomenon, Lupus, Rheumatoid Arthritis, Scleroderma, Antiphospholipid syndrome, Celiac disease (4 hours).
Congenital and acquired immunodeficiencies (2 hours).
Thrombotic Microangiopathies: thrombotic thrombocytopenic purpura (2 hours).
Plastic Surgery Module (MED/19, 1 CFU, 12 hours)

Anatomy of the skin and its appendages. Wound healing: normal and pathological healing (hypertrophic scars, keloids, ulcers, pressure sores). Skin grafts: definition, classification, and stages of grafting. Flaps: definition, classification, and indications (3 hours).
Burns: definition, staging, clinical classification, lesions, and therapy/treatment in adults and children. Precancerous lesions and skin cancers (basal cell carcinoma, squamous cell carcinoma, melanomas): characteristics, definitions, classification, diagnosis, and prevention (3 hours).
Genital transformation: diagnosis and treatment of gender dysphoria, fallopoiesis, and edoiopoiesis. Post-mastectomy breast reconstruction: reconstruction techniques and aesthetic breast augmentation. Vulvovaginal surgery: pelvic-perineal superficial reconstruction, malformations, and genitourinary syndromes (imperforate hymen, vaginal agenesis, vulvovaginal atrophy) (3 hours).
Hypertrophy, asymmetry, and hypoplasia of the breasts. Malformations: hypospadias, epispadias, cleft lip and palate, polydactyly, syndactyly. Pressure ulcers (3 hours).
Pharmacology Module (BIO/14, 1 CFU, 12 hours)

Introduction to Pharmacology: general concepts of pharmacological action, drug origins, preclinical and clinical trials (2 hours).
Pharmacokinetics (ADME): routes of drug administration, absorption, and distribution (2 hours).
Pharmacokinetics (ADME): metabolism and elimination, pharmacokinetic parameters (2 hours).
Pharmacodynamics: drug-receptor interaction, mechanisms of action, channel and metabotropic receptors, tyrosine kinase receptors, and intracellular receptors (3 hours).
Pharmacological interactions, adverse drug reactions, and pharmacovigilance, introduction to pharmacogenetics (3 hours).

	Teaching Methods
	The course consists of lectures. Classroom attendance is mandatory. To take the final exam, students must attend at least 75% of the classes. Attendance will be monitored through Easyacademy software.

	Verification of learning
	The exam consists of an oral test with a 15-minute interview for each module. The goal is to assess the student’s level of knowledge and understanding, as well as their ability to present and organize the material autonomously using appropriate terminology. The final grade is determined by the weighted average of the grades from the various modules. For honors, the collective evaluation will consider the student’s knowledge of the topics and the quality of their presentation in terms of appropriate scientific language and interdisciplinary connections.

Verification of learning

The exam consists of an oral test with a 15-minute interview for each module. The goal is to assess the student’s level of knowledge and understanding, as well as their ability to present and organize the material autonomously using appropriate terminology. The final grade is determined by the weighted average of the grades from the various modules. For honors, the collective evaluation will consider the student’s knowledge of the topics and the quality of their presentation in terms of appropriate scientific language and interdisciplinary connections.

	Texts
	RAVAIOLI A., MANUALE DI ONCOLOGIA PER INFERMIERI. ED. IL PENSIERO SCIENTIFICO, 2010. SANTANELLI F CHIRURGIA PLASTICA RICOSTRUTTIVA ED ESTETICA. DVD. POZZI EDIZIONI SCUDERI RUBINO CHIRURGIA PLASTICA ED PICCIN FARMACOLOGIA GENERALE E MOLECOLARE, A CURA DI F. CLEMENTI, G. FUMAGALLI, UTET, FARMACOLOGIA PER LE PROFESSIONI SANITARIE, CONFORTI- IDELSON-GNOCCHI. COSTANTINI W: OSTETRICIA. ED PICCIN

	More Information
	NONE

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Stefano PEPE | GYNECOLOGIC PATHOLOGY OF GLANDS