HEMATOLOGY, ONCOHEMATOLOGY AND ONCOLOGY EXAM

Stefano PEPE HEMATOLOGY, ONCOHEMATOLOGY AND ONCOLOGY EXAM

1060100094
DEPARTMENT OF MEDICINE, SURGERY AND DENTISTRY "SALERNITANA MEDICAL SCHOOL"
EQF7
MEDICINE AND SURGERY
2024/2025

OBBLIGATORIO
YEAR OF COURSE 4
YEAR OF DIDACTIC SYSTEM 2016
SPRING SEMESTER
CFUHOURSACTIVITY
1ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - MOD ONCOLOGIA MEDICA
336LESSONS
2ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE - MOD MALATTIE DEL SANGUE
336LESSONS
3ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE AFP - MOD ONCOLOGIA MEDICA
125INTERNAL STAGE
4ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL SANGUE AFP - MOD MALATTIE DEL SANGUE
125INTERNAL STAGE
ExamDate
ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL 30/01/2025 - 09:00
ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL 30/01/2025 - 09:00
ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL 18/02/2025 - 09:00
ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL 18/02/2025 - 09:00
ONCOLOGIA EMATOONCOLOGIA E MALATTIE DEL 22/04/2025 - 09:00
Objectives
THIS COURSE WILL PROVIDE KNOWLEDGE ON PATHOGENETIC MECHANISMS UNDERLYING THE MAIN NEOPLASTIC AND NON-NEOPLASTIC HEMOPATHIES (INCLUDING COAGULATION DISORDERS) AND SOLID NEOPLASMS, INTEGRATING BASIC KNOWLEDGE AND INFORMATION DERIVING FROM CLINICAL AND LABORATORY STUDIES, AS WELL AS ALLOWING ACQUISITION OF DIAGNOSTIC ELEMENTS ESSENTIAL FOR CORRECT STAGING, PROGNOSIS, AND THERAPEUTIC DECISIONS.

KNOWLEDGE AND UNDERSTANDING ABILITY
KNOW AND BE ABLE TO DESCRIBE THE PRINCIPAL HEMOPATHIES AND SOLID TUMORS.
KNOW AND BE ABLE TO DESCRIBE EPIDEMIOLOGY OF TUMORS AND RELATIONSHIPS BETWEEN RISK FACTORS AND PROBABILITY OF NEOPLASM ONSET.
KNOW AND BE ABLE TO DESCRIBE METHODS, TIMING, EFFECTIVENESS/USEFULNESS AND EXPECTED RESULTS OF SCREENING (ALSO IN RELATION TO INDIVIDUAL RISK) FOR THE MOST FREQUENT TUMORS.
KNOW THE PRINCIPLES OF METHODOLOGY APPLIED TO DESIGN AND INTERPRETATION OF CLINICAL TRIALS.
KNOW HOW TO READ AND INTERPRET SCIENTIFIC LITERATURE.
DEEPEN KNOWLEDGE ON DIAGNOSIS, PROGNOSIS, AND THERAPY REGARDING THE FOLLOWING PATHOLOGIES: BREAST CANCER, GASTROINTESTINAL CARCINOMAS, LUNG CARCINOMAS, MELANOMA, GENITOURINARY SYSTEM TUMORS.
KNOW THE PRACTICAL CONCEPTS OF CHEMOTHERAPY.

ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING
KNOW AND BE ABLE TO RECOGNIZE CLINICAL MANIFESTATIONS OF THE PRINCIPAL HEMOPATHIES AND SOLID TUMORS.
KNOW AND KNOW HOW TO MANAGE SYMPTOMS RELATED TO TUMORS AND/OR SIDE EFFECTS OF CHEMOTHERAPIES AND TARGETED THERAPIES.
KNOW DIAGNOSTIC-THERAPEUTIC-CARE PROCESS OF HEMOPATHIES AND SOLID TUMORS AND DEVELOP A VISION IN THE CONTEXT OF THE DIFFERENT CARE ACTIVITIES.

INDEPENDENCE OF JUDGMENT
THE STUDENT MUST BE ABLE TO EVALUATE AND DEAL WITH THE INDIVIDUAL'S STATE OF HEALTH FROM A PREVENTIVE, DIAGNOSTIC, THERAPEUTIC AND REHABILITATIVE POINT OF VIEW AND INTEGRATE THIS KNOWLEDGE INTO A UNITARY VISION OF ONCOLOGICAL PATIENT.

COMMUNICATION SKILLS
KNOW THE TECHNIQUES OF DOCTOR-PATIENT COMMUNICATION AND KNOW HOW TO APPLY THE SAME IN THE COMMUNICATION OF ONCOLOGICAL AND ONCOHEMATOLOGICAL DIAGNOSES.

ABILITY TO LEARN
THE STUDENT MUST HAVE DEVELOPED THOSE LEARNING SKILLS THAT ALLOW TO CONTINUE STUDYING MOSTLY IN A SELF-DIRECTED OR AUTONOMOUS WAY, AND TO SEARCH INTO THE MAIN INTERNATIONAL DATABASES FOR THE MOST UP-TO-DATE INFORMATION ON DIAGNOSIS AND TREATMENT OF SOLID AND HEMATOLOGICAL TUMORS.
Prerequisites
THE STUDENT MUST HAVE ALREADY ACQUIRED, THROUGH PREVIOUS COURSES, KNOWLEDGE ON GENERAL MECHANISMS OF NEOPLASTIC TRANSFORMATION AND PHYSIOPATHOLOGY OF TUMOR DISEASES, BOTH BLOOD AND SOLID NEOPLASMS. FURTHERMORE, THE STUDENT MUST KNOW THE PATHOPHYSIOLOGY OF THE MAIN COAGULATION SYNDROMES AND DISORDERS, AS WELL AS MECHANISMS OF ACTION OF THE MOST IMPORTANT CLASSES OF ANTINEOPLASTIC DRUGS.
Contents
THIS COURSE IS DIVIDED INTO 2 MODULES, CALLED HEMATOONCOLOGY AND BLOOD DISEASES; AND ONCOLOGY.

HEMATOLOGY PROGRAM:
THE COURSE WILL FOCUS ON EPIDEMIOLOGY, NATURAL HISTORY, DIAGNOSIS, STAGING, PROGNOSIS, AND PRINCIPLES OF THERAPY OF THE MOST COMMON NON-NEOPLASTIC AND NEOPLASTIC BLOOD DISEASES, AND HEMOSTASIS.
1.ANEMIAS: CLASSIFICATION, DIAGNOSIS, AND TREATMENT OF THE MAIN ANEMIAS (IRON DEFICIENCY ANEMIA, MEGALOBLASTIC ANEMIA, ENZYME DEFICIENCY ANEMIA, PAROXYSMAL NOCTURNAL HEMOGLOBINURIA, IMMUNOLOGICAL HEMOLYTIC ANEMIAS, STRUCTURAL HEMOGLOBINOPATHIES: SICKLE CELL DISEASE, HEREDITARY SPHEROCYTOSIS, THALASSEMIA SYNDROMES).
2.BONE MARROW FAILURE SYNDROMES (MEDULLARY APLASIA, HYPOPLASTIC MYELODYSPLASIA, T-LGL).
3.ACUTE LYMPHOID LEUKEMIA
4.ACUTE MYELOID LEUKEMIA
5.MYELOPROLIFERATIVE SYNDROMES: POLYCYTHEMIA, THROMBOCYTHEMIA, MYELOFIBROSIS, CHRONIC MYELOID LEUKEMIA.
6.CHRONIC LYMPHOCYTIC LEUKEMIA
7.MYELODYSPLASTIC SYNDROMES
8.MULTIPLE MYELOMA AND IMMUNOPROLIFERATIVE SYNDROMES
9.HODGKIN'S AND NON-HODGKIN'S LYMPHOMAS
10.THROMBOCYTOPENIA AND THROMBOCYTOPATHIES, AND GENERAL CLASSIFICATION OF HEMORRHAGIC DISEASES, HEMOPHILIA AND VON WILLEBRAND'S DISEASE
11.VENOUS AND ARTERIAL THROMBOEMBOLISM: PROPHYLAXIS AND THERAPY
12.MARROW TRANSPLANT AND CAR-T THERAPY

ONCOLOGY PROGRAM:
GENERAL PART.
PRINCIPLES OF TUMOR BIOLOGY: MECHANISMS OF NEOPLASTIC TRANSFORMATION, INVASION, AND METASTASIS.
PRINCIPLES OF TUMOR EPIDEMIOLOGY.
CANCER PREVENTION: PRIMARY PREVENTION, SECONDARY PREVENTION (SCREENINGS) AND CHEMOPREVENTION.
CLINICAL APPROACH TO PATIENTS WITH CANCER: DIAGNOSIS, STAGING, PROGNOSTIC AND PREDICTIVE FACTORS, THERAPEUTIC PLANNING.
PRINCIPLES OF ANTI-TUMOR THERAPY: ROLE OF RADIOTHERAPY, SURGERY AND MEDICAL THERAPIES.
RATIONAL BASES OF MEDICAL THERAPY FOR CANCER: ADJUVANT THERAPY, NEOADJUVANT THERAPY, THERAPY OF ADVANCED DISEASE.
CHEMOTHERAPY; HORMONE THERAPY; THERAPY WITH NEW MOLECULARLY TARGETED DRUGS. SIDE EFFECTS OF DRUGS.
PRINCIPLES OF SUPPORTIVE THERAPY.
PRINCIPLES OF CLINICAL METHODOLOGY IN ONCOLOGY.

SPECIALIST PART
DIAGNOSIS, STAGING AND TREATMENT OF THE FOLLOWING NEOPLASIES:
BREAST CANCERS;
LUNG CANCERS;
GASTRO-INTESTINAL CANCERS (ESOPHAGUS, STOMACH, PANCREAS, COLORECTAL);
PROSTATE CANCERS;
OVARIAN TUMORS;
GERMINAL CANCERS;
KIDNEY TUMORS;
MELANOMA.

THE PROFESSIONAL TRAINING ACTIVITIES WILL FOCUS ON THE BEDSIDE ACQUISITION OF THE MOST IMPORTANT HEMATOLOGICAL AND ONCOLOGICAL PATHOLOGIES.
Teaching Methods
THE COURSE IS DIVIDED INTO FRONTAL LESSONS (72 HOURS) AND 50 HOURS OF PROFESSIONAL TRAINING ACTIVITIES. THE LECTURES WILL ALLOW THE STUDENT TO ACQUIRE KNOWLEDGE OF THE PATHOGENESIS, DIAGNOSIS, AND TREATMENT OF THE MAIN TUMORS. EXERCISES WILL ALLOW THE STUDENT TO DEVELOP THE ABILITY TO APPLY THIS KNOWLEDGE TO CLINICAL PRACTICE THROUGH THE DISCUSSION OF CLINICAL CASES.
Verification of learning
THE EXAM INCLUDES A WRITTEN AND AN ORAL TEST, BOTH MANDATORY. THE WRITTEN TEST CONSISTS OF 15 HEMATOLOGY QUESTIONS WITH 4 POSSIBLE ANSWERS AND ONLY ONE CORRECT, AND 15 ONCOLOGY QUESTIONS WITH 5 POSSIBLE ANSWERS AND ONLY ONE CORRECT, TO BE COMPLETED IN 30 MINUTES. THE FOLLOWING SCORES ARE ASSIGNED:
•2 FOR EACH CORRECT ANSWER
•0 FOR EACH NO RESPONSE
•0 FOR EACH INCORRECT ANSWER
TO BE ADMITTED TO THE ORAL TEST, IT IS NECESSARY TO OBTAIN A MINIMUM SCORE OF 18/30 IN BOTH THE HEMATOLOGY AND ONCOLOGY WRITTEN TESTS. THE FINAL GRADE IS A WEIGHTED AVERAGE OF THE GRADE OF THE WRITTEN TEST AND THAT OF THE ORAL TEST. THE WRITTEN TEST EVALUATES, IN ADDITION TO SPECIFIC KNOWLEDGE, THE STUDENT'S LOGICAL REASONING SKILLS. IN THE ORAL TEST, THE STUDENT'S KNOWLEDGE OF THE PHYSIOPATHOLOGY AND CLINICAL ASPECTS OF THE MAIN HEMATOLOGICAL DISORDERS IS ASSESSED IN A CONVERSATIONAL MANNER.
REGISTRATION FOR THE EXAM MUST BE DONE ONLINE AND TESTS ARE HELD IN THE CLASSROOMS OF THE MEDICINE TEACHING CENTER OF THE AOU "SAN GIOVANNI DI DIO E RUGGI D'ARAGONA" IN SALERNO.
Texts
AMADORI G. EMATOLOGIA - LE BASI FISIOPATOLOGICHE MOLECOLARI E CLINICHE. EDITORE PICCIN, 2010.
TURA S. LEZIONI DI EMATOLOGIA. EDITORE ESCULAPIO. VI EDIZIONE, 2011.
CORSO DI MALATTIE DEL SANGUE E DEGLI ORGANI EMOLINFOPOIETICI. AUTORI: TURA, CAVO, ZINZANI, BROCCOLI. EDITORE: SOCIETÀ EDITRICE ESCULAPIO; 7° EDIZIONE (2020). ISBN-10: 8893852039.
MANUALE DI MALATTIE DEL SANGUE. BOSI, DE STEFANO, DI RAIMONDO, LA NASA - ELSEVIER
EMATOLOGIA. PER MEDICINA, SCIENZE BIOLOGICHE, BIOTECNOLOGIE MEDICHE. N. GIULIANI, A. OLIVIERI - IDELSON-GNOCCHI.

LA MEDICINA ONCOLOGICA. DIAGNOSI, TERAPIA E GESTIONE CLINICA. LABIANCA R, CASCINU S. ED. EDRA. ISBN: 9788821430756
LINEE GUIDA AIOM (ASSOCIAZIONE DI ONCOLOGIA MEDICA)
J. NIEDERHUBER, J. ARMITAGE, J. DOROSHOW, M. KASTAN, J. TEPPER - ABELOFF’S CLINICAL ONCOLOGY - 6TH EDITION - 2019 – ELSEVIER.
COLLEGIO DEGLI ONCOLOGI MEDICI ITALIANI - MANUALE DI ONCOLOGIA MEDICA - 2018 - EDIZIONI MINERVA MEDICA
More Information
TEACHING MATERIALS SHARED BY THE PROFESSORS
  BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2025-01-27]