GAETANA PAOLELLA | CELLULAR BIOCHEMISTRY

cod. 0521500002

CELLULAR BIOCHEMISTRY

	0521500002
	DEPARTMENT OF CHEMISTRY AND BIOLOGY "ADOLFO ZAMBELLI"
	EQF7
	BIOLOGY
	2022/2023

CURRICULUM BIOINFORMATICS

	OBBLIGATORIO
	YEAR OF COURSE 1
	YEAR OF DIDACTIC SYSTEM 2022
	AUTUMN SEMESTER

TEACHING UNITS

SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
BIO/10	5	40	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
BIO/10	1	12	LAB	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	IVANA CAPUTO T Curriculum
	GAETANA PAOLELLA Curriculum

	Objectives
	KNOWLEDGE AND UNDERSTANDING: THE AIM OF THE COURSE IS TO GIVE KNOWLEDGE AT THE MOLECULAR LEVEL OF THE MAJOR CELL PROCESSES, IN PARTICULAR OF THE MOLECULAR MECHANISMS REGULATING PROTEIN LOCALIZATION AND TRAFFICKING, SIGNALLING AND CYTOSKELETON DYNAMICS. APPLICATION OF KNOWLEDGE AND UNDERSTANDING: THE AIM OF THE COURSE IS ALSO TO HELP THE DEVELOPMENT OF SKILLS ON BIOCHEMICAL STRATEGIES FOR EXPERIMENTAL STUDIES OF CELL PROCESSES.

KNOWLEDGE AND UNDERSTANDING:
THE AIM OF THE COURSE IS TO GIVE KNOWLEDGE AT THE MOLECULAR LEVEL OF THE MAJOR CELL PROCESSES, IN PARTICULAR OF THE MOLECULAR MECHANISMS REGULATING PROTEIN LOCALIZATION AND TRAFFICKING, SIGNALLING AND CYTOSKELETON DYNAMICS.

APPLICATION OF KNOWLEDGE AND UNDERSTANDING:
THE AIM OF THE COURSE IS ALSO TO HELP THE DEVELOPMENT OF SKILLS ON BIOCHEMICAL STRATEGIES FOR EXPERIMENTAL STUDIES OF CELL PROCESSES.

	Prerequisites
	THERE ARE NO REQUIRED EXAMS. HOWEVER, POSSESSING SKILLS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY IS STRONGLY RECOMMENDED.

	Contents
	-BIOCHEMISTRY OF CELL MEMBRANES (2 H). -PROTEIN FOLDING AND PROTEASOME (2 H). -CELL COMPARTMENTS AND PROTEIN TARGETING TO ORGANELLES (5 H). -VESICULAR TRAFFICKING; EXOCYTOSIS AND ENDOCYTOSIS (5 H). -SIGNAL TRASDUCTION; G-PROTEIN-COUPLED RECEPTORS. ENZYMES-COUPLED RECEPTORS. REGULATED PROTEOLYSIS (8 H). -BIOCHEMISTRY OF CYTOSKELETON; MICROFILAMENTS, MICROTUBULES, INTERMEDIATE FILAMENTS. MOLECULAR MOTORS (7 H). -BIOCHEMISTRY OF CELL CYCLE (4 H). REGULATION OF CELL GROWTH, CELL PROLIFERATION AND CELL DEATH; APOPTOSIS (3 H). BIOCHEMISTRY OF CELL ADHESION; ADHESION PROTEINS: CADERINS AND INTEGRINS (2 H). EXTRACELLULAR MATRIX: STRUCTURE AND FUNTION OF ITS PROTEINS (2 H). -INTERACTIVE DISCUSSION IN THE CLASSROOM ON SELECTED TOPICS (2 H). -VIDEO ON IN DEPTH ANALYSES (2 H). -PRACTICE EXERCISE ON IMMUNOFLUORESCENCE AND CELL BIOLOGY METHODS (8 H).

Contents

-BIOCHEMISTRY OF CELL MEMBRANES (2 H).
-PROTEIN FOLDING AND PROTEASOME (2 H).
-CELL COMPARTMENTS AND PROTEIN TARGETING TO ORGANELLES (5 H).
-VESICULAR TRAFFICKING; EXOCYTOSIS AND ENDOCYTOSIS (5 H).
-SIGNAL TRASDUCTION; G-PROTEIN-COUPLED RECEPTORS. ENZYMES-COUPLED RECEPTORS. REGULATED PROTEOLYSIS (8 H).
-BIOCHEMISTRY OF CYTOSKELETON; MICROFILAMENTS, MICROTUBULES, INTERMEDIATE FILAMENTS. MOLECULAR MOTORS (7 H).
-BIOCHEMISTRY OF CELL CYCLE (4 H).
REGULATION OF CELL GROWTH, CELL PROLIFERATION AND CELL DEATH; APOPTOSIS (3 H).
BIOCHEMISTRY OF CELL ADHESION; ADHESION PROTEINS: CADERINS AND INTEGRINS (2 H).
EXTRACELLULAR MATRIX: STRUCTURE AND FUNTION OF ITS PROTEINS (2 H).
-INTERACTIVE DISCUSSION IN THE CLASSROOM ON SELECTED TOPICS (2 H).
-VIDEO ON IN DEPTH ANALYSES (2 H).
-PRACTICE EXERCISE ON IMMUNOFLUORESCENCE AND CELL BIOLOGY METHODS (8 H).

	Teaching Methods
	LECTURES IN THE CLASSROOM WITH PROJECTION OF TEACHING MATERIALS IN ELECTRONIC FORM. EXERCISES IN CLASS. LABORATORY PRACTISES. TO ATTEND LESSONS IS NOT MANDATORY.

	Verification of learning
	THE ACHIEVEMENT OF TEACHING AIMS WILL BE VERIFIED BY MEANS OF A WRITTEN EXAMINATION, WITH A DURATION OF 90 MINUTES. THE WRITTEN TEST CONSISTS OF A COMBINATION OF QUESTIONS WITH DIRECT AND OPEN ANSWERS (4 QUESTIONS WITH DIRECT ANSWER, 3 PT EACH; 3 QUESTIONS WITH OPEN ANSWER, 6 PT EACH). THE EXAMINATION IS AIMED TO VERIFY THE ACQUISITION OF: KNOWDLEDGE AND EXPERTISES ON SUBJECTS OF THE COURSE; ABILITY TO CORRECTLY APPLY THEORETICAL KNOWLEDGE; ABILITY TO UNDERSTAND PROPOSED PROBLEMS; ADEQUATE LANGUAGE SKILLS.THE SUM OF POINTS FOR EACH ANSWER WILL GIVE A MARK OF 30/30.HONORS WILL BE GIVEN WHEN THE STUDENT DISPLAYS EXCELLENT SKILL ON THEORETICAL SUBJECTS AND EXCELLENT COMMAND OF LANGUAGE IN THE WRITTEN PRESENTATION.

Verification of learning

THE ACHIEVEMENT OF TEACHING AIMS WILL BE VERIFIED BY MEANS OF A WRITTEN EXAMINATION, WITH A DURATION OF 90 MINUTES. THE WRITTEN TEST CONSISTS OF A COMBINATION OF QUESTIONS WITH DIRECT AND OPEN ANSWERS (4 QUESTIONS WITH DIRECT ANSWER, 3 PT EACH; 3 QUESTIONS WITH OPEN ANSWER, 6 PT EACH).
THE EXAMINATION IS AIMED TO VERIFY THE ACQUISITION OF: KNOWDLEDGE AND EXPERTISES ON SUBJECTS OF THE COURSE; ABILITY TO CORRECTLY APPLY THEORETICAL KNOWLEDGE; ABILITY TO UNDERSTAND PROPOSED PROBLEMS; ADEQUATE LANGUAGE SKILLS.THE SUM OF POINTS FOR EACH ANSWER WILL GIVE A MARK OF 30/30.HONORS WILL BE GIVEN WHEN THE STUDENT DISPLAYS EXCELLENT SKILL ON THEORETICAL SUBJECTS AND EXCELLENT COMMAND OF LANGUAGE IN THE WRITTEN PRESENTATION.

	Texts
	IN ORDER TO REACH A FRUITFUL LEARNING ONE OF THE FOLLOWING TEXTS IS ADVISED: ALBERTS ET AL., BIOLOGIA MOLECOLARE DELLA CELLULA, ZANICHELLI. REFERENCE BOOKS ARE ALSO: GINELLI-MALCOVATI, MOLECOLE, CELLULE E ORGANISMI-EDISES. LODISH ET AL., BIOLOGIA MOLECOLARE DELLA CELLULA, ZANICHELLI.

BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-08-21]

GAETANA PAOLELLA | CELLULAR BIOCHEMISTRY