FARMACOLOGIA E TOSSICOLOGIA MEDICA

Amelia FILIPPELLI FARMACOLOGIA E TOSSICOLOGIA MEDICA

1060100087
DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA"
CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 6 ANNI
MEDICINE AND SURGERY
2014/2015

OBBLIGATORIO
YEAR OF COURSE 3
YEAR OF DIDACTIC SYSTEM 2012
SECONDO SEMESTRE
CFUHOURSACTIVITY
1FARMACOLOGIA E TOSSICOLOGIA - MOD. 1
540LESSONS
2FARMACOLOGIA E TOSSICOLOGIA - MOD. 2
324LESSONS
Objectives
AT THE END OF THE COURSE THE STUDENT SHOULD KNOW:
- THE MAIN MECHANISMS OF PHARMACODYNAMICS AND SIGNAL TRANSDUCTION;
- THE PRINCIPLES OF BIOLOGICAL ASSAY AND PRECLINICAL TESTING OF DRUGS;
- THE PHASES OF CLINICAL TRIALS, REGISTRATION OF DRUGS AND PHARMACOSURVEILLANCE;
- THE PHARMACOKINETIC MECHANISMS AND PARAMETERS;
- THE MAIN TOXICOLOGY MECHANISMS;
- THE MECHANISM OF ACTION, PHARMACOKINETICS, CLINICAL USES, SIDE EFFECTS AND DOSES OF DRUG USED IN MAJOR DISEASES.
THE STUDENT SHOULD BE ALSO ABLE TO PERFORM LITERATURE SEARCHES FOR THE ACQUISITION OF UPDATED INFORMATION ON THE MECHANISM OF ACTION AND SIDE EFFECTS OF MEDICATIONS.

Prerequisites
THE STUDENT SHOULD KNOW THE BASICS OF CHEMISTRY, ANATOMY, BIOCHEMISTRY, GENETICS, PHYSIOLOGY, GENERAL PATHOLOGY, IMMUNOLOGY AND CLINICAL PATHOPHYSIOLOGY TO UNDERSTAND THE GENERAL MECHANISM OF DRUG ACTION AND INTERACTION OF XENOBIOTICS WITH THE BODY.

Contents
PHARMACODYNAMICS. PRINCIPLES OF BIOLOGICAL ASSAY. RESEARCH AND DRUG DEVELOPMENT. PHARMACOKINETICS. ELEMENTS OF TOXICOLOGY. MOLECULAR PHARMACOLOGY. NEUROTRANSMISSION: THE AUTONOMIC AND SOMATIC MOTOR NERVOUS SYSTEMS. NEUROTRANSMISSION AND THE CENTRAL NERVOUS SYSTEM. MODULATION OF CARDIOVASCULAR AND RENAL FUNCTION AND VASCULAR VOLUME. INFLAMMATION, IMMUNOMODULATION, AND HEMATOPOIESIS. DRUGS AFFECTING GASTROINTESTINAL FUNCTION. DRUGS ACTING ON THE ENDOCRINE SYSTEM AND METABOLIC DISEASES. MEDICATIONS TO TREAT PAIN AND MUSCULOSKELETAL DISORDERS. CHEMOTHERAPY OF MICROBIAL AND NEOPLASTIC DISEASES. DRUG ADDICTION.
Teaching Methods
LECTURES, SEMINARS
Verification of learning
INDIVIDUAL ORAL EXAM
Texts
GOODMAN & GILMAN'S THE PHARMACOLOGICAL BASIS OF THERAPEUTICS, 12TH EDITION, EDITED BY L. BRUNTON, B. CHABNER, B. KNOLLMAN, MCGRAW HILL, NEW YORK 2011.
More Information
COMPULSORY ATTENDANCE - MINIMUM PERCENTAGE 75%
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