2. Professors
  3. FRANCI Gianluigi
  4. Teaching

General Pathology and Microbiology

Gianluigi FRANCI General Pathology and Microbiology

1012400007
DEPARTMENT OF MEDICINE, SURGERY AND DENTISTRY "SALERNITANA MEDICAL SCHOOL"
EQF6
MIDWIFERY
2024/2025

OBBLIGATORIO
YEAR OF COURSE 1
YEAR OF DIDACTIC SYSTEM 2013
SPRING SEMESTER
CFUHOURSACTIVITY
1PATOLOGIA GENERALE E MICROBIOLOGIA - MOD. PATOLOGIA GENERALE
224LESSONS
2PATOLOGIA GENERALE E MICROBIOLOGIA - MOD. PATOLOGIA CLINICA
112LESSONS
3PATOLOGIA GENERALE E MICROBIOLOGIA - MOD. MICROBIOLOGIA E MICROBIOLOGIA CLINICA
112LESSONS
4PATOLOGIA GENERALE E MICROBIOLOGIA - MOD. MEDICINA DI LABORATORIO
224LESSONS
VIVIANA IZZO4 T Curriculum
ROBERTA TARALLO1 Curriculum
-2
GIANLUIGI FRANCI3 Curriculum
Objectives
THE CLASS OF GENERAL PATHOLOGY AND MICROBIOLOGY IS DIVIDED IN 4 MODULES. THE COURSE PROVIDES THE STUDENT WITH THE NECESSARY KNOWLEDGE FOR THE UNDERSTANDING OF THE HUMAN DISEASES AND THEIR BASIC CELLULAR AND MOLECULAR PATHOPHYSIOLOGICAL MECHANISMS. ADDITIONAL AIM OF THE COURSE IS TO PROVIDE KNOWLEDGE ABOUT CELLULAR AND MOLECULAR BASES RESPONSIBLE FOR MICROBIAL ACTIVITY, MICRO-ORGANISM /GUESTS INTERACTIONS AND RELATED DIAGNOSTIC-CLINICAL ASPECTS. FINALLY, THE COURSE AIMS AT PROVIDING THE STUDENT WITH THE NECESSARY TOOLS TO RECOGNIZE THE MAIN BIOMARKERS TO DETERMINE ONGOING PATHOLOGIES.
IN ACCORDANCE WITH THE DUBLIN DESCRIPTORS, AT THE END OF THE CLASS AND TO PASS THE EXAM, THE STUDENT MUST BE ABLE TO:
• HAVE ACHIEVED KNOWLEDGE AND UNDERSTANDING OF THE MAIN PROCESSES IN GENERAL PATHOLOGY, CLINICAL PATHOLOGY, CLINICAL MICROBIOLOGY AND LABORATORY MEDICINE. KNOWING THE STANDARD VALUES OF ROUTINE EXAMINATIONS AND KNOWING HOW TO DIFFERENTIATE PHYSIOLOGICAL AND PATHOLOGICAL PICTURES. KNOWING HOW TO PROPERLY INTERPRET LABORATORY TESTS IN THE CONTEXT OF CLINICAL MICROBIOLOGICAL DIAGNOSTICS.
• APPLY THEORETICAL KNOWLEDGE TO THE CLINICAL AND LABORATORY FIELD, KNOWING HOW TO RECOGNIZE THE GENERAL DIAGNOSTIC ASPECTS OF BIOCHEMICAL, HAEMATOLOGICAL AND INFECTIOUS DISEASES. DISCUSS AND PERFORM CORRELATIONS ON SIMPLE DATA OR HYPOTHESES.
• KNOWING HOW TO INDEPENDENTLY AND CRITICALLY EVALUATE ANY DIFFERENT OPINIONS PRESENT IN CERTAIN TOPICS COVERED DURING THE COURSE. RECOGNIZE THE FUNDAMENTAL ROLE OF CORRECT THEORETICAL KNOWLEDGE OF THE SUBJECT IN CLINICAL PRACTICE AND IN THE FUTURE OBSTETRIC PROFESSION.
• KNOWING HOW TO PRESENT THE ARGUMENTS ORALLY IN AN ORGANIZED WAY AND WITH SEMANTIC APPROPRIATENESS AND IN ACCORDANCE WITH THE TOPIC OF DISCUSSION. AT THE SAME TIME BEING ABLE TO COMMUNICATE CRITICALLY WITH THEIR PEERS ON THE TOPICS STUDIED AND TO SUPPORT INTERDISCIPLINARY ARGUMENTS.
• RECOGNIZE THE IMPORTANCE AND SPECTRUM OF POSSIBLE APPLICATIONS OF THE SKILLS ACQUIRED IN THE FUTURE PROFESSIONAL CAREER.
Prerequisites
BASIC BIOLOGICAL KNOWLEDGE CONCERNING METABOLISM AND CELL SUBSTRUCTURE. BASIC BIOCHEMICAL KNOWLEDGE REGARDING THE STRUCTURE AND FUNCTION OF THE MAIN CLASSES OF BIOLOGICAL MACROMOLECULES.
Contents
THE COURSE IS DIVIDED INTO 4 MODULES: GENERAL PATHOLOGY WITH 2 CFU, PATHOLOGICAL ANATOMY WITH 2 CFU, INTERNAL MEDICINE WITH 1 CFU, METHODOLOGIES WITH 1 CFU. THE COURSE INCLUDES 72 HOURS OF LESSONS IN WHICH THE TOPICS WILL BE ADDRESSED:
GENERAL PATHOLOGY
INTRODUCTION TO GENERAL PATHOLOGY
BAROPATHIES
BAROTRAUMA
PATHOLOGIES FROM HIGH AND LOW TEMPERATURES
RADIATION DAMAGE
DISEASES DUE TO THE ELECTRICAL ENERGY TRANSFER
PATHOLOGIES DUE TO MECHANICAL ENERGY TRANSFER
CHEMICAL CAUSES OF PATHOLOGIES
CELL DAMAGE
MODES OF ADAPTATION:
- HYPOTROPHY
-HYPERTROPHY
-ATROPHY
-HYPERPLASIA
- METAPLASIA
- HYPOPLASIA
-APLASIA
-DYSPLASIA
CELL DEATH:
-NECROSIS
- APOPTOSIS
TUMORS
BLOOD AND MAJOR BLOOD DISORDERS
INFLAMMATION

PATHOLOGICAL ANATOMY
- ROLE AND FUNCTIONS OF PATHOLOGICAL ANATOMY
- THE PATHOLOGICAL ANATOMY LABORATORY
- METHODS IN PATHOLOGICAL ANATOMY
- BIOPSY AND SURGICAL SAMPLES
- FIXATION AND STAINING OF SAMPLES
- CELL DAMAGE
- CELL DEATH
- ACUTE AND CHRONIC INFLAMMATION
- THE REPARATIVE PROCESSES
- CYTOPATHOLOGY
- IMMUNOHISTOCHEMISTRY
- THE NEOPLASIA: GENERAL CHARACTERISTICS
- LYMPHOMAS AND LEUKEMIA
- BREAST CANCER
- RENAL AND BLADDER NEOPLASMS
- SKIN NEOPLASMS
- NEOPLASMS OF THE UTERUS AND OVARY
- NEOPLASMS OF THE PROSTATE AND TESTICLE
- NEOPLASMS OF THE GASTROINTESTINAL TRACT

INTERNAL MEDICINE
HYPERTENSION
ISCHEMIC HEART DISEASE
CHEST PAIN
RESPIRATORY FAILURE
COPD
ANEMIAS
DIABETES MELLITUS
DISEASES OF THE LIVER
ABDOMINAL PAIN
ACUTE AND CHRONIC RENAL FAILURE

METHODOLOGIES IN LABORATORY MEDICINE:
- BIOMARKERS
- BIOLOGICAL MATRICES
- VARIABILITY OF THE LABORATORY DATA
- ANALYTICAL TECHNIQUES:
O - SPECTROSCOPIC TECHNIQUES
O -ELECTROPHORETIC TECHNIQUES
O - CHROMATOGRAPHIC TECHNIQUES
O - CENTRIFUGATION TECHNIQUES
O - IMMUNOCHEMICAL AND IMMUNOENZYMATIC TECHNIQUES
- COMPLETE BLOOD COUNT
- COAGULATION
- LIVER FUNCTION
- RENAL FUNCTION
Teaching Methods
FRONTAL LESSONS AND SEMINARS. THE TEACHING REQUIRES THE OBLIGATION OF FREQUENCY, AT LEAST 75% OF THE PROVIDED HOURS FOR THE SINGLE MODULE IS NECESSARY TO SUSTAIN THE ORAL EXAMINATION.
Verification of learning
THE ACHIEVEMENT OF THE TEACHING OBJECTIVES IS CERTIFIED BY PASSING AN ORAL EXAM WITH AN EVALUATION IN THIRTIETHS. THE EXAM, AS A WHOLE, MAKES IT POSSIBLE TO ASCERTAIN BOTH THE CAPACITY FOR KNOWLEDGE AND UNDERSTANDING, AND THE ABILITY TO APPLY THE SKILLS ACQUIRED, BOTH THE ABILITY TO EXHIBIT, AND THE ABILITY TO LEARN AND DEVELOP SOLUTIONS INDEPENDENTLY. ALL THE PROFESSORS WILL PARTICIPATE IN THE OVERALL COLLECTIVE ASSESSMENT OF THE STUDENT'S PROFIT.

Texts
- AA VV PATOLOGIA GENERALE E FISIOPATOLOGIA, IDELSON – GNOCCHI
- ROBBINS, KUMAE &KLATT- LE BASI PATOLOGICHE DELLE MALATTIE, EDRA MASSON.
- MICROBIOLOGIA MEDICA, BATTERIOLOGIA E VIROLOGIA DI MARIA PIA CONTE, PAOLA MASTROMARINO. SOCIETÀ EDITRICE ESCULAPIO.

ELEMENTI DI BIOCHIMICA CLINICA E MEDICINA DI LABORATORIO. MARCELLO CIACCIO. EDISES EDIZIONI.

TEACHING MATERIALS: SLIDES OF THE LECTURES
More Information
THE OFFICIAL TEACHING LANGUAGE IS ITALIAN. LESSONS WILL BE HELD AT THE UNIVERSITY HOSPITAL "SAN GIOVANNI DI DIO E RUGGI D'ARAGONA" IN SALERNO.
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