Davide DE BIASE | GENERAL PATHOLOGY AND VETERINARY PHYSIOPATHOLOGY
Davide DE BIASE GENERAL PATHOLOGY AND VETERINARY PHYSIOPATHOLOGY
cod. 0712300014
GENERAL PATHOLOGY AND VETERINARY PHYSIOPATHOLOGY
| 0712300014 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF6 | |
| PHARMACEUTICALS AND NUTRACEUTICALS FOR ANIMALS | |
| 2024/2025 |
| OBBLIGATORIO | |
| YEAR OF COURSE 2 | |
| YEAR OF DIDACTIC SYSTEM 2022 | |
| SPRING SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| VET/03 | 6 | 48 | LESSONS |
| Exam | Date | Session | |
|---|---|---|---|
| GENNAIO | 05/02/2025 | SESSIONE ORDINARIA | |
| GENNAIO | 05/02/2025 | SESSIONE DI RECUPERO |
| Objectives | |
|---|---|
| The course aims to teach the students the knowledge about the fundamental pathological processes of cells and tissues. In addition, the course aims to provide the student with the understanding of the basic concepts of etiology and pathogenesis, the mechanisms of alteration of homeostasis and onset and development of the main animal diseases. At the end of the course the student will be able: to describe the cellular and tissue response to the different pathogenic noxae; to describe the mechanisms regulating acute and chronic inflammation, as well as the reparative process; to recognize the cellular modifications associated with malignant transformation; to describe the pathophysiological mechanisms associated with common cardiac, vascular, hemostatic, pulmonary, gastro-enteric, hepatic and renal disorders by identifying the possible/multiple inducing causes; to recognize the histological lesions caused by physico-chemical causes and biological agents and describe the morphological aspects and the etio-pathogenetic mechanisms related to the most common animal diseases. The student has to be able to identify and recognize the main pathological processes affecting cells and tissues. Moreover, the student has to acquire the ability to describe aetiology, pathogenesis and pathophysiology of a pathological process. |
| Prerequisites | |
|---|---|
| In order to follow the course and take the exam of general pathology and veterinary pathophysiology, the exams of anatomy and animal physiology and biology are propaedeutic. The teaching of general pathology and veterinary pathophysiology presupposes, in fact, a good knowledge of the functions and cellular mechanisms and of the morphology and function of the main organs and systems. |
| Contents | |
|---|---|
| General pathology - introduction (introduction to the course - concept of homeostasis and disease) 1 hour - general etiology (physical causes of illness - radiation and burns; chemical causes of disease; living agents as a cause of disease; genetic-hereditary causes) 4 hours - cell and tissue death (necrosis, apoptosis) 4 hours Adaptive mechanisms (hypertrophy, hypotrophy, metaplasia) 2 hours - cell degenerations (turbid swelling, hydropic degeneration, vacuolar degeneration, mucous degeneration, fatty degeneration or steatosis, cholesterinosis - atheromas) 2 hours - extracellular degenerations (hyaline degeneration, fibrinoid degeneration or necrosis, mucous degeneration of connective tissues, amyloid degeneration or amyloidosis), pathological pigmentations 2 hours - the acute inflammatory process or angiophlogosis (phases of angiophlogosis, vasomotor alterations in the course of angiophlogosis, cell activation, diapedesis and phagocytosis, chemical mediators of the inflammatory process, classification of exudates, the acute phase reaction) 2 hours - the chronic inflammatory process or histophlogosis (interstitial histophlogosis, granulomatous histophlogosis) 2 hours - wound repair (healing mechanisms for first and second intention) 2 hours - tumors (definitions and nomenclature, morphological, biochemical and metabolic neoplastic atypias, mechanisms of oncogenesis, molecular oncogenesis, the stages of neoplastic development, metastasis, cachexia and paraneoplastic syndromes, immunity and tumors) 8 hours Veterinary pathophysiology - circulation disorders (hyperemia, edema, ischemia, heart attack, thrombosis, embolism, shock) 2 hours - pathophysiology of thermoregulation (non-febrile hyperthermia, fever) 1 hour - immunopathology (hypersensitivity reactions (type i, ii, iii, iv), autoimmune diseases, immunodeficiencies 6 hours - pathophysiology of the endocrine system (hypo and hyperfunctional syndromes of pituitary, thyroid, adrenocortical syndrome, general adaptation syndrome (stress), diabetes mellitus) 6 hours - pathophysiology of metabolism (bovine ketosis and pregnancy toxemia of small ruminants, neonatal hypoglycemia of piglets; puerperal collapse) 4 hours. |
| Teaching Methods | |
|---|---|
| The course "general pathology and veterinary pathophysiology" - credits: 6 (n° hours of lessons: 48) is divided into lectures carried out in the classroom with the aid of slides, for its entire duration. The lectures will allow the student to acquire the basic knowledge on the general etiology cause of disease and on the alteration of cellular homeostasis responsible for pathological events such as defensive, progressive and neoplastic processes. The course will also include the development of an individual / group work through the presentation of a power point in the classroom and aimed at acquiring the ability to independently carry out a bibliographic research and to develop a presentation. The development of the paper will be discussed with the class in 20 minutes of the course and individually with the student during the teacher's reception hours. |
| Verification of learning | |
|---|---|
| The exam consists of a discussion about the course subjects. The exam, will last about 25-30 minutes and will verify the theoretical knowledge with particular reference to the fundamental pathological processes of the cell and tissues as well as the etiology, pathogenesis and mechanisms of alteration of homeostasis and onset and development of the main animal diseases. The test is passed (with a score between 18 and 30 thirtieths) if the candidate has acquired an overall view of the course subjects, relating different topics to correctly answer the questions posed, through good reasoning skills and autonomy of judgment. The candidate's ability to express himself clearly and to use the correct terminology of the subject will also be evaluated. The exam is therefore evaluated for: clarity, synthesis and reasoning skills, problem solving capacity and ability to link between related topics. |
| Texts | |
|---|---|
| • Kumar v, et al. Robbins and Cotran pathologic basis of disease. 10th ed. Chapters 1 to 9. • Zachary JF. Pathologic basis of veterinary disease. 7th ed. Chapters 1 to 6. |
BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2025-01-27]
