GIUSEPPE IACOMINO | Curriculum
GIUSEPPE IACOMINO Curriculum
Giuseppe Iacomino is a senior staff scientist at the "Istituto di Scienze dell'Alimentazione" - Consiglio Nazionale delle Ricerche (CNR). In 1989, he earned his Laurea degree cum Laude in Biological Science at the University of Naples. From 1988 to 1990, he worked in the laboratories of prof. Zappia (Biochemistry, Faculty of Medicine - University of Naples), and from 1991 to 1997, in the laboratories of prof. Cascino (Molecular Biology, Faculty of Medicine - University of Naples). He received a PhD in Biochemistry and specialized in Biochemistry and Clinical Chemistry. G. Iacomino's main experience is in the fields of Biochemistry, Cell Biology, Molecular Biology, Cancer prevention, Cancer Biology, and Nutritional Biochemistry. His research has been focused, at the molecular level, on different aspects of food, from chemo-prevention to diet-related diseases. His main expertise is in epigenomics, gene expression control, the role of chromatin modifiers in affecting transcriptional activity, the cell cycle, and apoptosis. In this respect, the downstream effects of nutrients with chromatin-modifying ability are emerging as fundamental aspects contributing to the response to food and individual nutrient intake. Scientific interests are also focused on the role of polyamines in governing the nuclear organization. It was found that polyamines self-assemble in the cell nucleus and generate compounds referred to as nuclear aggregates of polyamines (NAPs) which interact with genomic DNA and regulate decisive aspects of DNA physiology, such as conformation, protection, and packaging. His scientific interests also cover the valorization of food and food products by studying bio-accessibility, bio-transformation, and transport using models of simulated digestion and human intestinal cells. His recent research activity addressed the differential signature of microRNAs in obesity and metabolic diseases. He currently serves as an associate editor for "Nutrition, Metabolism and Cardiovascular Diseases" Elsevier and “Genes” MDPI and regularly reviews scientific manuscripts for international Journals in cell and molecular biology, nutritional biochemistry, and food disorders.
orcid: 0000-0001-5231-2231
Scopus Author ID: 6602605591
Publications
Giuseppe Iacomino, José Ángel Rufian Henares and Fabio Lauria
“Personalized nutrition and gut microbiota: current and future directions”
Frontiers in Nutrition, 2024. Volume 11. https://doi.org/10.3389/fnut.2024.1375157
Salvatore De Caro, Antonella Venezia, Luigia Di Stasio, Donatella Danzi, Domenico Pignone, Gianfranco Mamone and Giuseppe Iacomino
“Tritordeum: Promising Cultivars to Improve Health”
Foods 2024, 13, 661. https://doi.org/10.3390/foods13050661
Russo, P.; Lauria, F.; Sirangelo, I.; Siani, A.; Iacomino, G.
“Association between Urinary AGEs and Circulating miRNAs in Children and Adolescents with Overweight and Obesity from the Italian I.Family Cohort: A Pilot Study”.
- Clin. Med. 2023, 12, 5362. https://doi.org/10.3390/jcm12165362
Giuseppe Iacomino
New Opportunities for miRNAs in Translational Medicine
Encyclopedia, MDPI. Entry ID: 43537, 2023
https://encyclopedia.pub/entry/43537
Giuseppe Iacomino
“miRNAs: The Road from Bench to Bedside”
Genes 2023, 14, 314. https://doi.org/ 10.3390/genes14020314
Giuseppe Mazzarella, Giuseppe Iacomino, Pasquale De Luca, Salvatore Iaquinto, Capuano Fabiana, Riccardo Troncone, Vera Rotondi Aufiero.
“Cell-type-specific gene expression profile by laser capture microdissection on mirror sections”
Journal of Immunological Methods, 2022, 505, 113276, https://doi.org/10.1016/j.jim.2022.113276
Giuseppe Iacomino, Fabio Lauria, Paola Russo, Antonella Venezia, Pasquale Marena, Wolfgang Ahrens, Stefaan De Henauw, Gabriele Eiben , Ronja Foraita, Antje Hebestreit, Yiannis Kourides , Dénes Molnár, Luis A Moreno, Toomas Veidebaum and Alfonso Siani. “Circulating miRNAs Are Associated with Inflammation Biomarkers in Children with Overweight and Obesity: Results of the I.Family Study”
Genes 2022, Volume 13, Issue 4, 632
Fabio Lauria and Giuseppe Iacomino. “The Landscape of Circulating miRNAs in the Post-Genomic Era”
Genes 2022, 13, 94. https://doi.org/10.3390/genes13010094
Giuseppe Iacomino, Fabio Lauria, Paola Russo, Antonella Venezia, Nunzia Iannaccone, Pasquale Marena, Wolfgang Ahrens, Stefaan De Henauw, Dénes Molnár, Gabriele Eiben, Ronja Foraita, Antje Hebestreit, Giannis Kourides, Luis A Moreno, Toomas Veidebaum, and Alfonso Siani. “The association of circulating miR-191 and miR-375 expression levels with markers of insulin resistance in overweight children: an exploratory analysis of the I.Family Study”
Genes & Nutrition, 2021, 16, 10. https://doi.org/10.1186/s12263-021-00689-1
Giuseppe Iacomino, Vera Rotondi Aufiero, Luigia Di Stasio, Stefania Picascia, Nunzia Iannaccone, Nicola Giardullo, Riccardo Troncone, Carmen Gianfrani, Gianfranco Mamone, Giuseppe Mazzarella
“Triticum monococcum amylase trypsin inhibitors possess a reduced potential to elicit innate immune response in celiac patients compared to Triticum aestivum”
Food Research International, 2021, 145, 110386. doi: https://doi.org/10.1016/j.foodres.2021.110386
Giuseppe Iacomino, Fabio Lauria, Paola Russo, Pasquale Marena, Antonella Venezia, Nunzia Iannaccone, Stefaan De Henauw, Ronja Foraita, Regina Heidinger-Felső, Monica Hunsberger, Yiannis Kourides, Luis A Moreno, Barbara Thumann, Toomas Veidebaum, Alfonso Siani.
“Circulating miRNAs are associated with sleep duration in children/adolescents: results of the I.Family Study “.
Experimental Physiology, 2020; 105: 347-356 https://doi.org/10.1113/EP088015
Gaetano Iaquinto, Vera Rotondi Aufiero, Nunzia Iannaccone, Iacomino G, Nicola Giardullo, Michele Schettino, Giuseppe Mazzarella (2020). “Potential Role Of TCRγΔ+ Intraepithelial Lymphocytes In Celiac Disease”. Gastroenterology, vol. 158, p. 1115-1116, ISSN: 0016-5085, doi: https://doi.org/10.1016/S0016-5085(20)33457-0
Giuseppe Iacomino, Vera Rotondi Aufiero, Nunzia Iannaccone, Raffaele Melina, Nicola Giardullo, Giovanni De Chiara, Antonella Venezia, Fabio Silvio Taccone, Gaetano Iaquinto, Giuseppe Mazzarella
“IBD: role of intestinal compartments in the mucosal immune response”.
Immunobiology, 225 (2020) 151849 doi.org/10.1016/j.imbio.2019.09.008
Antonella Venezia, Paola Pedata, Giulia Ricci, Livia Malorni, Nunzia Iannaccone, Marcella Cammarota, Maria Grazia Volpe, Vincenzo Guida, Chiara Schirardi, Marco Romano, Giuseppe Iacomino.
“Intestinal epithelium responses to titanium dioxide nanoparticles”
Nutrition Metabolism & Cardiovascular Diseases. 2019, 29, 8, 872 . https://doi.org/10.1016/j.numecd.2019.05.009
Giuseppe Iacomino, Paola Russo, Pasquale Marena , Fabio Lauria , Antonella Venezia , Nunzia Iannaccone , Wolfgang Ahrens, Stefaan De Henauw , Pasquale De Luca , Ronja Foraita , Kathrin Günther , Lauren Lissner , Dénes Molnár , Luis A Moreno, Michael Tornaritis , Toomas Veidebaum , Alfonso Siani.
“Plasma microRNA expression profiles are associated with early childhood obesity: Results of the I.Family Study”.
Nutrition Metabolism & Cardiovascular Diseases. 2019, 29, 8, 864. https://doi.org/10.1016/j.numecd.2019.05.014
Giuseppe Iacomino, Paola Russo, Pasquale Marena, Fabio Lauria, Antonella Venezia, Wolfgang Ahrens, Stefaan De Henauw, Pasquale De Luca, Ronja Foraita, Kathrin Günther, Lauren Lissner, Dénes Molnár, Luis A Moreno, Michael Tornaritis, Toomas Veidebaum, and Alfonso Siani.
“Circulating microRNAs expression profiles are associated with early childhood obesity: results of the I.Family Study”.
Genes & Nutrition, 2019, 14:2. doi.org/10.1186/s12263-018-0622-6
Maristella De Cicco, Francesco Siano, Giuseppe Iacomino, Nunzia Iannaccone, Luigia Di Stasio, Gianfranco Mamone, Maria Grazia Volpe, Pasquale Ferranti, Francesco Addeo, Gianluca Picariello.
“Multianalytical detection of pig-derived ingredients in bread"
Food Analytical Methods, 2018, doi.org/10.1007/s12161-018-01410-6
Paola Pedata, Giulia Ricci, Livia Malorni, Antonella Venezia, Marcella Cammarota, Maria Grazia Volpe, Nunzia Iannaccone, Vincenzo Guida, Chiara Schirardi, Marco Romano, Giuseppe Iacomino.
Intestinal epithelium responses to titanium dioxide nanoparticles.
Food Research International, 2018, doi.org/10.1016/j.foodres.2018.10.041
Gianfranco Mamone and Giuseppe Iacomino
“Comparison of the in vitro toxicity of ancient Triticum monococcum varieties ID331 and Monlis”
International Journal of Food Sciences and Nutrition. 2018, doi.org/10.1080/09637486.2018.1444019
Gianluca Picariello, Luigia Di Stasio, Gianfranco Mamone, Giuseppe Iacomino, Antonella Venezia, Nunzia Iannaccone, Pasquale Ferranti, Raffaele Coppola, Francesco Addeo
“Identification of enzyme origin in dough improvers: DNA-based and proteomic approaches”
Food Research International ,2018, 105, 52-58
Giuseppe Iacomino, Vera Rotondi Aufiero, Pasquale Marena, Antonella Venezia, Riccardo Troncone, Salvatore Auricchio, and Giuseppe Mazzarella. “Laser Capture Microdissection as a Tool to Study the Mucosal Immune Response in Celiac Disease”
Methods in Molecular Biology, 2018, vol. 1723, 7; https://doi.org/10.1007/978-1-4939-7558-7_7
Giuseppe Iacomino & Alfonso Siani
“Role of microRNAs in obesity and obesity-related diseases”
Genes & nutrition, 2017, 12, 23. https://doi.org/10.1186/s12263-017-0577-z
Giuseppe Iacomino, Gianluca Picariello, Francesca Sbrana, Roberto Raiteri, and Luciano D’Agostino.
“DNA and HMGB1 interaction: the Nuclear Aggregates of Polyamines mediation.”
BBA-proteins proteomics 2016, doi:10.1016/j.bbapap.2016.07.006
Gaetano Iaquinto, Vera Rotondi Aufiero, Iacomino Giuseppe, Giuseppe Mazzarella, Michele Schettino and Armando Masucci (Celiac disease: role of intestinal compartments in the mucosal immune response.
FASEB JOURNAL, 2016, vol. 30 (suppl 1), p. 921.10-1, ISSN: 0892-6638
Iacomino G, Russo P,Stillitano I, Lauria F, Marena P, Ahrens W, Siani A
“Circulating miRNAs are deregulated in prepubertal overweight/obese children: preliminary results of the IFamily Study”
Genes & Nutrition 11 (1), 1, 2016: doi:10.1186/s12263-016-0525-3
Giuseppe Iacomino, Luigia Di Stasio, Olga Fierro, Gianluca Picariello, Antonella Venezia,Laura Gazza, Pasquale Ferranti , Gianfranco Mamone
“Protective effects of ID331 Triticum monococcum gliadin on in vitro models of the intestinal epithelium”
Food Chemistry (2016) 212 537–542. DOI: 10.1016/j.foodchem.2016.06.014
Iacomino Giuseppe, Marano Angela, Stillitano Ilaria, Rotondi Aufiero Vera, Iaquinto Gaetano, Giardullo Nicola, Troncone Riccardo, Auricchio Salvatore, and Mazzarella Giuseppe
“Celiac disease: role of intestinal compartments in the mucosal immune response”
Mol Cell Biochem 2016 Vol. 411 Issue 1-2 Pages 341-9, PMID: 26541753. DOI: 10.1007/s11010-015-2596-7
G Iacomino, P Russo, I Stillitano, F Lauria, P Marena, W Ahrens & A Siani
Circulating miRNAs are deregulated in overweight/obese children: preliminary results of the IFamily study.
Obesity facts, 2015, 8 (suppl 1) , 40
Editore: S. Karger - Basel -ISSN: 1662-4025
https://doi.org/10.1159/000382140
Giuseppe Iacomino, Gianluca Picariello, Ilaria Stillitano, Luciano D’Agostino
“Nuclear aggregates of polyamines in a radiation-induced DNA damage model”
The International Journal of Biochemistry & Cell Biology, 47 (2014) 11– 19. doi: 10.1016/j.biocel.2013.11.007
Picariello Gianluca, Iacomino Giuseppe, Di Luccia Aldo, D'Agostino, Luciano
“Mass spectrometry analysis of in vitro Nuclear Aggregates of Polyamines”
Rapid Communications in Mass Spectrometry, 2014, 28, 499–504. DOI: 10.1002/rcm.6807
Gaetano Iaquinto, Vera Rotondi Aufiero, Marco Preziuso, Angela Marano, Ilaria Stillitano, Nicola Giardullo, Rosa Maria Bevilacqua, Giuseppe Iacomino and Giuseppe Mazzarella.”Cytokine Profile in Celiac Disease: a Laser Capture Microdissection Approach”
The FASEB Journal. 2013;27:645.4
Iacomino, Giuseppe; Fierro, Olga; D'Auria, Sabato; Picariello, Gianluca; Ferranti, Pasquale; liguori, claudia; Addeo, Francesco; Mamone, Gianfranco.
"Structural analysis and Caco-2 cell permeability of the celiac-toxic A-gliadin peptide 31-55"
- Agric. Food Chem., 2013, 61 (5), pp 1088–1096. DOI: 10.1021/jf3045523
- Tedesco, M. Russo, S. Bilotto, C. Spagnuol, A. Scognamiglio, R. Palumbo, A. Nappo, G. Iacomino, L. Moio, G.L. Russo.
“Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line”
Food and Chemical Toxicology, 60 (2013) 377–384. https://doi.org/10.1016/j.fct.2013.07.078.
Gianluca Picariello, Giuseppe Iacomino, Gianfranco Mamone, Pasquale Ferranti, Olga Fierro, Carmen Gianfrani, Aldo Di Luccia, Francesco Addeo. “Transport across Caco-2 monolayers of peptides arising from in vitro digestion of bovine milk proteins”
Food Chemistry, 2013, 139, 1–4, 203–212. DOI: 10.1016/j.foodchem.2013.01.063
Giuseppe Iacomino, Gianluca Picariello, Luciano D'Agostino.
“DNA and nuclear aggregates of polyamines”
Biochimica et Biophysica Acta 1823 (2012) 1745–1755. DOI: 10.1016/j.bbamcr.2012.05.033
Giuseppe Iacomino, Gianluca Picariello, Francesca Sbrana, Aldo di Luccia, Roberto Raiteri, Luciano D’Agostino.
“DNA is Wrapped by Nuclear Aggregates of Polyamines: The Imaging Evidence”
Biomacromolecules (2011), 12, 4, 1178–1186. DOI: 10.1021/bm101478j
Iacomino Giuseppe Picariello, Gianluca; D'Agostino Luciano.
“The in vitro Nuclear Aggregates of Polyamines.”
FEBS, (2009), 276: Supplement 1, 96
Di Luccia, Aldo; Picariello, Gianluca; Iacomino Giuseppe; Formisano, Annarita; D'Agostino, Luciano.
“The in vitro Nuclear Aggregates of Polyamines.”
FEBS, (2009), 276: 2324–2335. DOI: 10.1111/j.1742-4658.2009.06960.x
Giuseppe Iacomino, Maria Cristina Medici and Gian Luigi Russo
“Valproic Acid Sensitizes K562 Erythroleukemia Cells to TRAIL/Apo2L-induced Apoptosis.”
Anticancer Research, 28: 855-864 (2008)
- Iacomino, M.C. Medici, D. Napoli, and G.L. Russo. “Effects of Histone Deacetylase Inhibitors on p55CDC/Cdc20 Expression in HT29 Cell Line,” Journal of Cellular Biochemistry, 2006, 99(4):1122 31. https://doi.org/10.1002/jcb.21014
- Tedesco, A. Nappo, F. Petitto, G. Iacomino, F. Nazzaro, R. Palumbo, and G. L. Russo
“Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line”
Nutrition & Cancer, (2005), 52(1), 74-83. https://doi.org/10.1207/s15327914nc5201_10
- Russo, I. Tedesco, G. Iacomino, R. Palumbo, G. Galano and G. L. Russo
“Dietary Phytochemicals in Chemoprevention of Cancer”
Curr. Med. Chem. – Immun., Endoc. & Metab. Agents, 2005, 5, 61-72. DOI: 10.2174/1568013053005454
Flavonoid quercetin enhances CD95 and TRAIL mediated apoptosis in different malignant cell lines.
Russo, GL ; Russo, M ; Nigro, P ; Rosiello, R ; Volpe, S ; Iacomino, G ; Tedesco, I ; Presidente, E ; Galano, G
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2004) Volume 13 Issue 11 Page 1886S-1886S
- Iacomino, M.C. Medici, D. Napoli and G.L. Russo
“Phosphorilation of SER-39 in p34 Cdc2 by CK2: looking for a role”
Italian J. Biochem. (2004), 53 (3), 107
Maria Russo, Rosanna Palumbo, Annalisa Mupo, Mariarosaria Tosto, Giuseppe Iacomino, Annamaria Scognamiglio, Idolo Tedesco, Giovanni Galano and Gian Luigi Russo.
“Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase C”
Oncogene (2003) 22, 3330–3342. DOI: 10.1038/sj.onc.1206493
- Russo, G.Iacomino, G. Galano, G.L. Russo.
“Quercetin Enhances CD95-Mediated Apoptosis in HPB-ALL Cells by Inhibiting Protein Kinase CK2”
Italian J. Biochem. (2003), 52(3), 109
G Iacomino, M.C. Medici, D. Napoli, GL Russo
“Effects of Histone Deacetilase Inhibitors on p55CDC (CELL DIVISION CYCLE) expression”
Italian J. Biochem. (2003), 52(3), 89
Giuseppe Iacomino, Mario Felice Tecce, Claudia Grimaldi, Mariarosaria Tosto, and Gian Luigi Russo. “Transcriptional Response of a Human Colon Adenocarcinoma Cell Line to Sodium Butyrate”
B.B.R.C., (2001), 285(5):1280-9. DOI: 10.1006/bbrc.2001.5323
Mariarosaria Santillo, Paolo Mondola, Rosalba Serù, Tiziana Annella, Silvana Cassano, Ilaria Ciullo, Mario F. Tecce, Giuseppe Iacomino, Simona Damiano, Giovanni Cuda, Roberto Paternò, Valeria Martignetti, Evelina Mele, Antonio Feliciello, and Enrico V. Avvedimento.
“Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals”
Current Biology, (2001), 11 (8), 614-9
Annalisa Mupo, Maria RUSSO, Giuseppe IACOMINO, Katia Raieta, Claudia Grimaldi, Elio De Nisco, Rosanna Palumbo e Gian Luigi Russo
“Effect of Quercetin on a Malignant Cell Line Resistant to CD95-Mediated Apoptosis”
Italian Biochemical Society Transactions (IBST), (2001) 18, 20
- Tedesco, M. Russo, P. Russo, G. Iacomino, G. L. Russo, A. Carraturo, C. Faruolo, L.Moio and R. Palumbo.
“Antioxidant effect of red wine polyphenols on red blood cells”
- Nutri. Biochem., (2000) 11, 114-119. DOI: 10.1016/s0955-2863(99)00080-7
G Iacomino, C Grimaldi, P Russo, GL Russo and MF Tecce. “Gene expression response of human epithelial colonic cell to sodium butyrate” Italian Biochemical Society Transactions (IBST), (2000) 15, 294
M Russo, A Mupo, G Iacomino, E Avvedimento, A Scognamiglio, R Palumbo and GL Russo. “Apoptotic effects of quercetin and CD95(FAS/APO1) in h-ras transformed Caco2 cell line” Italian Biochemical Society Transactions (IBST), (2000) 15, 187
- Russo, R. Palumbo, G. Iacomino C. Turco, M. F. Tecce I. Tedesco, V. Zappia and G. L. Russo (1998). “Quercetin and Fas (Fas/Apo1/CD95) induce apoptosis in Caco2 cell line”
Italian J. Biochem., 1999 48(3):189-190.
- Russo, R. Palumbo, I. Tedesco, G. Mazzarella, P. Russo, G. Iacomino and G. L. Russo (1999). “Quercetin and anti-CD95 (Fas/Apo1) enhance apoptosis in HPB-ALL cell line”
FEBS Letters, 462 (1999), 322-328. DOI: 10.1016/s0014-5793(99)01544-6
- L. Russo, V. Della Pietra, C. Mercurio, R. Palumbo, G. Iacomino, M. Russo, M. Tosto, and V.Zappia.
Protective Effects of Butyric Acid in Colon Cancer
Adv.Exp.Med.Biol. (2000) 472, 131-147. DOI: 10.1007/978-1-4757-3230-6_12
G.Iacomino, U. Galderisi, M. Cipollaro, E. Piegari, G. Di Bernardo, L. Berrino, F. Rossi and A. Cascino. “Antisense Inhibition of Hypertension: a New Therapeutic Strategy”
Italian Journal of Biochemistry, (1998), 47 (3) 201-202
- Galderisi, M. Cipollaro, G. Di Bernardo, G.Iacomino, G. Galano and A. Cascino
“Identification of Italian Sweet Chestnut Cultivars by Random Amplified Polimorphic DNA Analysis”
Italian Journal of Biochemistry (1998), 47 (3) 199-200
- Di Bernardo, A. Forte, G. Galano, U. Galderisi, G. Iacomino, A. Cascino and M. Cipollaro. “Mitochondrial DNA analysis of skeletal remains of Caius Julius Polibius house in Pompeii”. Italian Journal of Biochemistry (1998),179-220
- A. B. Melone, U. Galderisi, G. Iacomino, M. Cipollaro, G. Di Bernardo, R. Cotrufo, G. Peluso and A. Cascino: "Use of antisense oligonucleotides to study the myotonin gene expression in C2 mouse cells"
Antisense Nucleic Acid Drug Dev 1998 Feb; 8 (1): 25-33; https://doi.org/10.1089/oli.1.1998.8.25
- Cipollaro, U. Galderisi, G. Galano, G. Iacomino, G. Di Bernardo, G. Lus, R. Cotrufo, A. Orsini, L. Santoro, L. Pastore, C. Sarrantonio, F. Salvatore and A. Cascino. “CTG repeat number in the nonaffected allele of myotonic dystrophy patients is not critical for disease expression”
Human Biology (1997): 69 (6), 887-890
- Cipollaro, G. Di Bernardo, G. Galano, G. Iacomino, U. Galderisi and A. Cascino: “Evolutionary aspects of DNA sequences coding for genetic disorders: DM-1 locus in the 79 A.D. ancient population of Pompeii”
Ancient Biomolecules, 1, (3), 253-254 (1997).
- Galderisi, M. Cipollaro, M.A.B. Melone, G. Iacomino, G. Di Bernardo, G. Galano, R. Cotrufo, V. Zappia and A. Cascino, “Myotonic dystrophy: antisense oligonucleotides inhibition of DMPK gene expression in vitro.”
B.B.R.C.: 221, 750-754, (1996). DOI:10.1006/bbrc.1996.0668
- Galderisi, M. Cipollaro, A. De Rienzo, G. Iacomino, S. De Falco, G. Galano, M.A.B. Melone, R. Cotrufo and A. Cascino. "Antisense Phosphorothioate Oligonucleotides as a Tool to Inhibit DM-1 Gene Expression"
Italian Journal of Biochemistry, 1994, 43 (3), 133-135
- Iacomino, M. Cipollaro, U. Galderisi, A. De Rienzo, S. De Falco, G. Galano, P. La Colla, M. E. Marongiu and A. Cascino.
"Phosphorothioated Antisense Oligonucleotides: Inhibition of HIV-1 Virus Development in Chronically and De Novo Infected Cells"
Italian Journal of Biochemistry, 1994, 43 (3), 131-133
- Iacomino, U. Galderisi, M. Cipollaro, S. Di Biase, P. La Colla, M. E. Marongiu, A. De Rienzo, S. De Falco, G. Galano and A. Cascino
"Phosphorothioated antisense oligonucleotides: prospects for AIDS therapy"
Life Science Advances: Molecular Biology, ISSN : 0971-5126, 1994, 13: 69-74
M.Porcelli, G.Cacciapuoti, S.Fusco, G. Iacomino, A.Gambacorta, M De Rosa, V.Zappia
"S-Adenosylhomocysteine hydrolase from the Thermophilic Archeon Sulfolobus solfataricus"
Biochem. Biophis. Acta, 1164 (1993) 179-188. DOI: 10.1016/0167-4838(93)90246-n
- Coppola, M. Cipollaro, G. Galano, U. Galderisi, G. Iacomino, A. Cascino
"Diagnosis of Myotonic dystrophy through detection of long CTG repeats in genomic DNA in patients from Southern Italy"
Italian Journal of Biochemistry, vol 42, N° 3, May-June 1993
- Cipollaro, U. Galderisi, S. Coppola, A. De Rienzo, G. Iacomino, G. Galano, A. Cascino, V. Zappia, G. Lus, G. Riccio and R. Cotrufo. "Genetic screening of Myotonic Dystrophy in family at risk"
Clinical Neuropathology, suppl n°1, vol 12, June 1993
- Cipollaro, U. Galderisi, A. De Rienzo, G. Iacomino, G. Galano, A. Cascino, V. Zappia, G. Lus, G. Riccio and R. Cotrufo. "Genetic screening of Myotonic Dystrophy"
Italian Journal of Biochemistry,1993, 42 (5), 358-360
- De Falco, G. Iacomino, U. Galderisi, M. Cipollaro, A. De Rienzo, G. Galano, A. Cascino, A. Loi, M. Spiga, T. Basile, D. Musu, A.De Montis, E. Tramontano, M. E. Marongiu and P. La Colla
"A Review on the in vitro activity of Phosphorothioate Oligonucleotides Against Human Immunodeficiency Viruses"
Minerva Biotecnologica Vol. 5, N° 4, Dicembre 1993
G.Cacciapuoti,M.Porcelli,C. Bertoldo, G. Iacomino, A. Martino and V.Zappia
“Studies on 5'-Methyltioadenosine phosphorylase from Sulfolobus solfataricus a highly thermophilic and Thermostabe enzyme”
Ital. J. Biochem. 41, 1, 1992
Book/Chapters
“The Ins and Outs of miRNAs as Biomarkers”
Giuseppe Iacomino and Fabio Lauria, Eds.
Published: June 2023 Pages: 254
ISBN 978-3-0365-7925-2 (hardback); ISBN 978-3-0365-7924-5 (PDF)
https://doi.org/10.3390/books978-3-0365-7924-5 (registering DOI)
“Circulating microRNA (miRNA)s as biological markers and links with childhood obesity and obesity-related morbid conditions”
Fabio Lauria, Antonella Venezia, G. Iacomino.
Ed Victor Preedy
Springer Nature series 2022. Biomarkers in Disease: Methods, Discoveries and Applications
https://doi.org/10.1007/978-3-030-81304-8_29-1
“MICRORNAS IN OBESITY AND METABOLIC DISEASES”
Giuseppe Iacomino, Fabio Lauria, Antonella Venezia, Nunzia Iannaccone, Paola Russo & Alfonso Siani.
Obesity and Diabetes: New Surgical and Nonsurgical Approaches, Cap 6. Ed. Joel Faintuch
Springer Nature 2020, ISBN 978-3-030-53369-4; https://doi.org/10.1007/978-3-030-53370-0_6#DOI
“Laser Capture Microdissection as a Tool to Study the Mucosal Immune Response in Celiac Disease”.
Giuseppe Iacomino, Vera Rotondi Aufiero, Pasquale Marena, Antonella Venezia, Riccardo Troncone, Salvatore Auricchio, and Giuseppe Mazzarella.
Graeme I. Murray (ed.), Laser Capture Microdissection: Methods and Protocols, Methods in Molecular Biology,
Vol. 1723, Chapter 7, (2018). Springer. https://doi.org/10.1007/978-1-4939-7558-7_7
“NATURAL POLYMER GENOMICS: PHOSPHATE-INDUCED SELF-ASSEMBLY OF POLYAMINES”
The Encyclopedia of Biomedical Polymers & Polymeric Biomaterials.
Picariello, Gianluca; Iacomino Giuseppe, D'Agostino Luciano.
1st Ed.; Mishra, M.
Taylor & Francis: New York, 2015; Vol. 8, p. 5951-5964. ISBN: 9781439898796; https://doi.org/10.1201/9781351237970
“BEER IN HEALTH AND DISEASE PREVENTION”
Cap. 47 -Biological Properties of Beer and Its Components Compared to Wine-
Giuseppe Iacomino, Idolo Tedesco and Gian Luigi Russo.
ELSEVIER ED, 2008
ISBN-13: 978-0-12-373891-2; ISBN-10: 0-12-373891-1
“PROBIOTICI E PEPTIDI BIOATTIVI”
Anticancer effects of butyrate a dietary fibre derivative
G.L. Russo & G. Iacomino.
MOFIN ED. 2007; Editorial Coordinator: Schiavi C.
“OLIGONUCLEOTIDI ANTISENSO: PRINCIPI E APPLICAZIONI”
Cap. 14 - Antisenso e Virus -
G.Iacomino e A. Cascino.
UTET ED., 1996
ISBN 88-02-05041-4
Other Pubblications
Giuseppe Iacomino, Luigia Di Stasio, Olga Fierro, Pasquale Ferranti, Gianfranco Mamone
“Grani ancestrali di T. monococco mostrano una minora tossicità intestinale in sistemi cellulari in vitro: implicazioni per la malattia celiaca”.
Tecniche molitorie, (2015)
Giuseppe Iacomino, Claudia Grimaldi e Gian Luigi Russo. “La Strategia Antisenso”
Biologi Italiani, (2002), 1, 24-32. ISSN 0329-2510
Comitato di redazione: M. Ascione, V. Barbaro, E. Calcatelli, M. Caruso, S. D’Antonio, L. di Natale, S. Dumontet, E. Landi, B. Nicolaus, F. Pastoni, V. Stefanelli, N. Tafuri.
Giuseppe Iacomino, Claudia Grimaldi e Gian Luigi Russo. “La Tecnologia del Gene Array”.
Biologi Italiani, (2001), 11, 16-21. ISSN 0329-2510
Comitato di redazione: M. Ascione, V. Barbaro, E. Calcatelli, M. Caruso, S. D’Antonio, L. di Natale, S. Dumontet, E. Landi, B. Nicolaus, F. Pastoni, V. Stefanelli, N. Tafuri.
G.L.Russo R.Palumbo P.Russo G.Iacomino M.Russo I.Tedesco and C.Faruolo
“Fattori Alimentari Chemiopreventivi”.
Ricerca & Futuro. Rivista del Consiglio Nazionale delle Ricerche. (1999) 12, 75-76
ISSN 1125-795x
Di Bernardo, G. Galano, U. Galderisi, G. Iacomino, D. Porzio, A. Cascino, F. M. Guarino, F. Angelini e M. Cipollaro: “Analisi dei reperti ossei della casa di Caius Iulius Polybius in Pompei: grado di conservazione ed amplificazione del DNA antico”, C.N.R. La casa di Polibio, (1997)
- Cipollaro, U. Galderisi, A. De Rienzo, S. De Falco, G. Iacomino, G. Lus, R. Cotrufo, L. Pastore, C. Sarrantonio, F. Salvatore and A. Cascino. "Anomalous distribution of the unaffected CTG repeats allele of DM patients"
Miami Bio/Technology European Symposium , Suppl. Nucl. Acid Res. 94
- Cascino, S. Di Biase , P. La Colla,M. Cipollaro, G. Iacomino, M. Santoro
"Inhibition of HIV-1 production in both chronically and de novo infected lymphocytes mediated by phosphorothioated antisense oligodeoxyribonucleotides"
Atti Associazione Genetica Italiana, Vol. XXXVII - 1991
Patents
- Brevetto a nome: Consiglio Nazionale delle Ricerche.
Inventori : A. Cascino, M. Cipollaro, G. Iacomino, U. Galderisi.
Titolo: “Oligonucleotidi in grado di modulare l'espressione del gene per la miotonina ed uso di essi” brevetto depositato il 6/5/96, verb. rm96a 00149
Application number: IT1996RM00149 19960306; Publication number: ITRM960149(A1)
Brevetto internazionale (A61K; C07H), il brevetto non ha dato luogo a contratti di licenza esclusiva o non esclusiva.
- Brevetto a nome: Consiglio Nazionale delle Ricerche.
Inventori: Antonino Cascino, Marilena Cipollaro, Giuseppe Iacomino e Umberto Galderisi.
Titolo: Oligonucleotidi in grado di modulare nel topo l'espressione del gene per la miotonina e usi di essi.
Autorizzazione richiesta in data 14/06/96.
