Ornella MOLTEDO | BIOCHEMISTRY AND PLANT GENETICS

cod. 0712100038

BIOCHEMISTRY AND PLANT GENETICS

	0712100038
	DIPARTIMENTO DI FARMACIA

	HERBAL SCIENCE
	2014/2015

PERCORSO COMUNE

	OBBLIGATORIO
	YEAR OF COURSE 2
	YEAR OF DIDACTIC SYSTEM 2010
	SECONDO SEMESTRE

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	PRINCIPI DI BIOCHIMICA MODULO DI BIOCHIMICA E GENETICA AGRARIA
	BIO/10	5	40	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
2	GENETICA AGRARIA MODULO DI BIOCHIMICA E GENETICA AGRARIA
	AGR/07	5	40	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	ORNELLA MOLTEDO1 T Curriculum
	ANTONIETTA LEONE2 Curriculum

	Objectives
	UNIT "PRINCIPLE OF BIOCHEMISTRY" 1) KNOWLEDGE AND UNDERSTANDING-: THE STUDENT MUST HAVE DEVELOPED THE ABILITY TO UNDERSTAND THE BASICS OF THE STRUCTURE AND MOLECULAR ORGANIZATION OF THE MAJOR BIOMOLECULES. KNOWING THE BASICS OF BIOENERGETICS AND THE GENERAL MEANING OF METABOLISM. 2) APPLYING KNOWLEDGE AND UNDERSTANDING: ABILITY TO USE THE BASICS ACQUIRED, TO KNOW HOW TO APPLY THE KNOWLEDGE OF BIOCHEMICAL PROCESSES, WITH PARTICULAR EMPHASIS ON THE STUDY OF BIOENERGETICS AND METABOLISM IN DIFFERENT ORGANS. 3) COMMUNICATION SKILLS: THE STUDENT WILL HAVE THE ABILITY TO FIND AND USE DATA USEFUL FOR SOLUTION OF SPECIFIC QUESTIONS OF THEORETICAL, AND TO ASSESS INDEPENDENTLY THE KNOWLEDGE ACQUIRED. 4) ABILITY COMMUNICATION : THE STUDENT WILL BE ABLE TO PRESENT THE MAIN BIOCHEMICAL MECHANISMS OF REGULATION AND INTEGRATION OF METABOLISM OF MAN, IN A CLEAR AND SIMPLE, EVEN TO A NON-SPECIALIST PUBLIC. 5) LEARNING SKILLS: THE STUDENT AT THE END WILL HAVE A THEORETICAL BACKGROUND THAT COVERS THE RELEVANT KNOWLEDGE OF THE CHEMICAL AND BIOCHEMICAL THE METABOLISM IN DIFFERENT ORGANS. UNIT "PLANT GENETICS" 1) KNOWLEDGE AND UNDERSTANDING- THE COURSE IN PLANT GENETICS IS DESIGNED TO OFFER TO THE STUDENTS BASIC KNOWLEDGE AND COMPREHENSION OF THE MOLECULAR MECHANISMS CONTROLLING THE MAIN PLANT CELLULAR FUNCTIONS, WITH MAJOR EMPHASIS ON PLANT CELLS, ANALYZING AND DISCUSSING THE BASIC PRINCIPLES OF GENETIC INHERITANCE OF TRAITS, AND THEIR APPLICATION TO THE BREEDING OF IMPORTANT TRAITS FOR MEDICINAL PLANTS, INCLUDING ALSO THE GENETIC MECHANISMS CONTROLLING THE BIOSYNTHESIS OF BIOACTIVE PLANT-DERIVED SECONDARY METABOLITES; 2) APPLYING KNOWLEDGE AND UNDERSTANDING-THE LECTURES AND THE PRACTICAL HAND-ON LABORATORY WILL GIVE TO THE STUDENTS THE THEORETICAL KNOWLEDGE AND THE PRACTICAL TOOLS NECESSARY TO UNDERSTAND THE GENETIC AND MOLECULAR MECHANISMS CONTROLLING ALL THE STEPS OF THE PLANT GROWTH, DIFFERENTIATION, DEVELOPMENT AND RE PRODUCTION, THE PLANT INTERACTION WITH THE ENVIRONMENT, THEIR ABILITY TO SYNTHESIZE SECONDARY METABOLITES AND COMPOUNDS OF INTEREST FOR THE HUMAN HEALTH; 3) COMMUNICATION SKILLS: THE COURSE WILL GIVE TO THE STUDENTS THE OPPORTUNITY TO ACQUIRE INTERDISCIPLINARY THEORETICAL KNOWLEDGE AND TECHNICAL TOOLS IN THE FIELD OF PLANT GENETICS USEFUL FOR GENETIC CHARACTERIZATION AND IMPROVEMENT OF MEDICINAL PLANTS, NECESSARY FOR ENTERING IN THE MARKET OF THE PRODUCTION AND QUALITY CONTROL OF MEDICINAL PLANTS AND THEIR DERIVATES; 4) ABILITY COMMUNICATION: STUDENTS WILL DEVELOP THE ABILITY TO DISCUSS, COMPARE AND ADDRESS IN AN AUTONOMOUS WAY SPECIFIC QUESTIONS OF PLANT GENETICS APPLIED TO MEDICINAL PLANTS AND MORE BROADLY WILL ACQUIRES KNOWLEDGE BY HIS OR HER OWN EFFORTS AND DEVELOPS THE ABILITY FOR INQUIRY AND CRITICAL EVALUATION OF QUESTIONS, PROBLEMS AND SUGGEST RELATIVE SOLUTIONS, ALSO THROUGH A CONTINUOS DISCUSSION WITH OTHER STUDENTS, TEACHERS AND PROFESSIONAL EXPERTS IN THE FIELD OF MEDICINAL PLANTS AND DERIVED HEALTH PROMOTING PRODUCTS.

UNIT "PRINCIPLE OF BIOCHEMISTRY"

1) KNOWLEDGE AND UNDERSTANDING-: THE STUDENT MUST HAVE DEVELOPED THE ABILITY TO UNDERSTAND THE BASICS OF THE STRUCTURE AND MOLECULAR ORGANIZATION OF THE MAJOR BIOMOLECULES. KNOWING THE BASICS OF BIOENERGETICS AND THE GENERAL MEANING OF METABOLISM.

2) APPLYING KNOWLEDGE AND UNDERSTANDING: ABILITY TO USE THE BASICS ACQUIRED, TO KNOW HOW TO APPLY THE KNOWLEDGE OF BIOCHEMICAL PROCESSES, WITH PARTICULAR EMPHASIS ON THE STUDY OF BIOENERGETICS AND METABOLISM IN DIFFERENT ORGANS.

3) COMMUNICATION SKILLS: THE STUDENT WILL HAVE THE ABILITY TO FIND AND USE DATA USEFUL FOR SOLUTION OF SPECIFIC QUESTIONS OF THEORETICAL, AND TO ASSESS INDEPENDENTLY THE KNOWLEDGE ACQUIRED.

4) ABILITY COMMUNICATION : THE STUDENT WILL BE ABLE TO PRESENT THE MAIN BIOCHEMICAL MECHANISMS OF REGULATION AND INTEGRATION OF METABOLISM OF MAN, IN A CLEAR AND SIMPLE, EVEN TO A NON-SPECIALIST PUBLIC.
5) LEARNING SKILLS: THE STUDENT AT THE END WILL HAVE A THEORETICAL BACKGROUND THAT COVERS THE RELEVANT KNOWLEDGE OF THE CHEMICAL AND BIOCHEMICAL THE METABOLISM IN DIFFERENT ORGANS.

UNIT "PLANT GENETICS"

1) KNOWLEDGE AND UNDERSTANDING- THE COURSE IN PLANT GENETICS IS DESIGNED TO OFFER TO THE STUDENTS BASIC KNOWLEDGE AND COMPREHENSION OF THE MOLECULAR MECHANISMS CONTROLLING THE MAIN PLANT CELLULAR FUNCTIONS, WITH MAJOR EMPHASIS ON PLANT CELLS, ANALYZING AND DISCUSSING THE BASIC PRINCIPLES OF GENETIC INHERITANCE OF TRAITS, AND THEIR APPLICATION TO THE BREEDING OF IMPORTANT TRAITS FOR MEDICINAL PLANTS, INCLUDING ALSO THE GENETIC MECHANISMS CONTROLLING THE BIOSYNTHESIS OF BIOACTIVE PLANT-DERIVED SECONDARY METABOLITES;

2) APPLYING KNOWLEDGE AND UNDERSTANDING-THE LECTURES AND THE PRACTICAL HAND-ON LABORATORY WILL GIVE TO THE STUDENTS THE THEORETICAL KNOWLEDGE AND THE PRACTICAL TOOLS NECESSARY TO UNDERSTAND THE GENETIC AND MOLECULAR MECHANISMS CONTROLLING ALL THE STEPS OF THE PLANT GROWTH, DIFFERENTIATION, DEVELOPMENT AND RE PRODUCTION, THE PLANT INTERACTION WITH THE ENVIRONMENT, THEIR ABILITY TO SYNTHESIZE
SECONDARY METABOLITES AND COMPOUNDS OF INTEREST FOR THE HUMAN HEALTH;

3) COMMUNICATION SKILLS: THE COURSE WILL GIVE TO THE STUDENTS THE OPPORTUNITY TO ACQUIRE INTERDISCIPLINARY THEORETICAL KNOWLEDGE AND TECHNICAL TOOLS IN THE FIELD OF PLANT GENETICS USEFUL FOR GENETIC CHARACTERIZATION AND IMPROVEMENT OF MEDICINAL PLANTS, NECESSARY FOR ENTERING IN THE MARKET OF THE PRODUCTION AND QUALITY CONTROL OF MEDICINAL PLANTS AND THEIR DERIVATES;
4) ABILITY COMMUNICATION: STUDENTS WILL DEVELOP THE ABILITY TO DISCUSS, COMPARE AND ADDRESS IN AN AUTONOMOUS WAY SPECIFIC QUESTIONS OF PLANT GENETICS APPLIED TO MEDICINAL PLANTS AND MORE BROADLY WILL ACQUIRES KNOWLEDGE BY HIS OR HER OWN EFFORTS AND DEVELOPS THE ABILITY FOR INQUIRY AND CRITICAL EVALUATION OF QUESTIONS, PROBLEMS AND SUGGEST RELATIVE SOLUTIONS, ALSO THROUGH A CONTINUOS DISCUSSION WITH OTHER STUDENTS, TEACHERS AND PROFESSIONAL EXPERTS IN THE FIELD OF MEDICINAL PLANTS AND DERIVED HEALTH PROMOTING PRODUCTS.

	Prerequisites
	UNIT PRINCIPLES OF BIOCHEMISTRY FOR AN ADEQUATE UNDERSTANDING OF THE TOPICS OF THIS COURSE IT IS NECESSARY THAT THE STUDENT HAS ACQUIRED THE OBJECTIVES RELATING TO THE FOLLOWING SUBJECTS: BIOLOGY, GENERAL CHEMISTRY, ORGANIC CHEMISTRY. UNIT "PLANT GENETICS" STUDENTS ARE REQUESTED TO HAVE A SOUND PREVIOUS KNOWLEWDGE IN PLANT BIOLOGY, BOTANY, ORGANIC CHEMISTRY AND BIOCHEMISTRY

	Contents
	UNIT PRINCIPLES OF BIOCHEMISTRY PROTEIN: THE AMINOACIDS. THE PEPTIDE BOND.STRUTTURA PRIMARY, SECONDARY, TERTIARY AND QUATERNARY. FIBROUS PROTEINS: COLLAGEN. GLOBULAR PROTEINS. PROTEINS THAT BIND OXYGEN: HEMOGLOBIN AND MYOGLOBIN. LIPIDS: FATTY ACIDS. FAT-SOLUBLE VITAMINS. LIPIDS: TRIGLYCERIDES, PHOSPHOLIPIDS. THE CHOLESTEROL. BIOENERGETICS AND METABOLISM: PRINCIPLES OF BIOENERGETICS. EXERGONIC AND ENDERGONIC REACTIONS. COMPOUNDS WITH HIGH POTENTIAL ENERGY: ROLE OF ATP AND OTHER PHOSPHOROUS COMPOUNDS. THE FLOW OF ENERGY IN LIVING ORGANISMS: ATP-ADP CYCLE. GENERAL CONCEPTS OF METABOLISM.METABOLISM OF CARBOHYDRATES: GLYCOLYSIS, GLUCONEOGENESIS AND METABOLISM OF INTERMEDIATE GLUCOSIO.METABOLISMO: KREBS CYCLE, RESPIRATORY CHAIN AND OXIDATIVE PHOSPHORYLATION. LIPID METABOLISM: BETA-OXIDATION AND SYNTHESIS OF FATTY ACIDS. NITROGEN METABOLISM: PROTEIN CATABOLISM. UREA CYCLE. UNIT "PLANT GENETICS" NUCLEIC ACIDS: DNA AND RNA CHEMICAL AND PHISICAL STRUCTURE; MITOSIS AND MEISOIS; DNA REPLICATION; CENTRAL DOGMA OF MOLECULAR BIOLOGY; GENE TRANSCRIPTION, GENE TRANSLATION; CONTROLLING STEPS AND MECHANISMS OF GEEN EXPRESSION; TRAIT INHERITANCE AND TRANSMISSIBILITY; MENDELIAN LAWS: DOMINANCE AND RECESSIVITY; INDEPENDENT TRAIT INHERITANCE ; EXTENCTIONS OD MENDELIAN LAWS: INCOMPLETE DOMINANCE, MULTIPLE ALLELES, CODOMINANCE; INTERALLIC INTERACTIONS AND EPISTASY; ASSOCIATED GENES; X-LINKED GENES AND GENETICAL DISEASES; EXTRA-NUCLEAR INHERITANCE; MUTATIONS: SPONTNEUS AND INDUCED MUTATIONS AND EVOLUTION, MUTAGENIC AGENTS; POINT MUTATIONS; CHROMOSOMAL MUTATIONS; GENOMIC MUTATIONS. PRINCIPLES OF DNA CLONING AND GENETIC ENGINEERING APPLIED TO IMPROVING QUALITY OF MEDICINAL PLANTS, EITH SPECIAL ENPHASIS ON THE GENETIC MECHANISMS CONTROLLING THE BIOSYNTHETIC PATHWAYS OF BIOACTIVE SECONDARY METABOLITES.

Contents

UNIT PRINCIPLES OF BIOCHEMISTRY
PROTEIN: THE AMINOACIDS. THE PEPTIDE BOND.STRUTTURA PRIMARY, SECONDARY, TERTIARY AND QUATERNARY. FIBROUS PROTEINS: COLLAGEN. GLOBULAR PROTEINS. PROTEINS THAT BIND OXYGEN: HEMOGLOBIN AND MYOGLOBIN. LIPIDS: FATTY ACIDS. FAT-SOLUBLE VITAMINS. LIPIDS: TRIGLYCERIDES, PHOSPHOLIPIDS. THE CHOLESTEROL. BIOENERGETICS AND METABOLISM: PRINCIPLES OF BIOENERGETICS. EXERGONIC AND ENDERGONIC REACTIONS. COMPOUNDS WITH HIGH POTENTIAL ENERGY: ROLE OF ATP AND OTHER PHOSPHOROUS COMPOUNDS. THE FLOW OF ENERGY IN LIVING ORGANISMS: ATP-ADP CYCLE. GENERAL CONCEPTS OF METABOLISM.METABOLISM OF CARBOHYDRATES: GLYCOLYSIS, GLUCONEOGENESIS AND METABOLISM OF INTERMEDIATE GLUCOSIO.METABOLISMO: KREBS CYCLE, RESPIRATORY CHAIN AND OXIDATIVE PHOSPHORYLATION. LIPID METABOLISM: BETA-OXIDATION AND SYNTHESIS OF FATTY ACIDS. NITROGEN METABOLISM: PROTEIN CATABOLISM. UREA CYCLE.

UNIT "PLANT GENETICS"
NUCLEIC ACIDS: DNA AND RNA CHEMICAL AND PHISICAL STRUCTURE; MITOSIS AND MEISOIS; DNA REPLICATION; CENTRAL DOGMA OF MOLECULAR BIOLOGY; GENE TRANSCRIPTION, GENE TRANSLATION; CONTROLLING STEPS AND MECHANISMS OF GEEN EXPRESSION; TRAIT INHERITANCE AND TRANSMISSIBILITY; MENDELIAN LAWS: DOMINANCE AND RECESSIVITY; INDEPENDENT TRAIT INHERITANCE ; EXTENCTIONS OD MENDELIAN LAWS: INCOMPLETE DOMINANCE, MULTIPLE ALLELES, CODOMINANCE; INTERALLIC INTERACTIONS AND EPISTASY; ASSOCIATED GENES; X-LINKED GENES AND GENETICAL DISEASES; EXTRA-NUCLEAR INHERITANCE; MUTATIONS: SPONTNEUS AND INDUCED MUTATIONS AND EVOLUTION, MUTAGENIC AGENTS; POINT MUTATIONS; CHROMOSOMAL MUTATIONS; GENOMIC MUTATIONS. PRINCIPLES OF DNA CLONING AND GENETIC ENGINEERING APPLIED TO IMPROVING QUALITY OF MEDICINAL PLANTS, EITH SPECIAL ENPHASIS ON THE GENETIC MECHANISMS CONTROLLING THE BIOSYNTHETIC PATHWAYS OF BIOACTIVE SECONDARY METABOLITES.

	Teaching Methods
	UNIT PRINCIPLES OF BIOCHEMISTRY TEACHING METHODS: LECTURES UNIT PLANT GENETICS THEORETCAL LECTURES; INTERACTIVE AND WEB TOOLS FOR STUDYING PLANT GENETICS; TRAINING LABORATORIES

	Verification of learning
	UNIT PRINCIPLES OF BIOCHEMISTRY WRITTEN AND ORAL EXAMINATION UNIT PLANT GENETICS WRITTEN TEST INCLUDING OPEN QUESTIONS AND MULTIPLE-CHOICE QUESTIONS MENDELIAN QUIZZES WRITTEN REPORTS ON TRAINING LABORATORIES ORAL PRESENTATION ON SELECTED TOPICS OF THE PROGRAMME

	Texts
	REFERENCE TEXTS: GENERAL TEXTS OF BIOCHEMISTRY OF RECENT EDITION LEHNINGER A.L., NELSON D.L. & COX M.M. PRINCIPI DI BIOCHIMICA ED. ZANICHELLI VOET E. & VOET J.G. BIOCHIMICA ED. ZANICHELLI STAYER L. BIOCHIMICA ED. ZANICHELLI

	More Information
	UNIT "PRINCIPLES OF BIOCHEMISTRY": FOR FURTHER INFORMATION; PLEASE CONTACT PROF. ORNELLA MOLTEDO (MOLTEDO@UNISA.IT) UNIT "PLANT GENETICS": FOR FURTHER INFORMATION, PLEASE CONTACT PROF. ANTONELLA LEONE (ALEONE@UNISA.IT)

BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2016-09-30]

Ornella MOLTEDO | BIOCHEMISTRY AND PLANT GENETICS