GENERAL BIOCHEMISTRY

Ornella MOLTEDO GENERAL BIOCHEMISTRY

0712300005
DIPARTIMENTO DI FARMACIA
EQF6
PHARMACEUTICALS AND NUTRACEUTICALS FOR ANIMALS
2024/2025

OBBLIGATORIO
YEAR OF COURSE 2
YEAR OF DIDACTIC SYSTEM 2022
SPRING SEMESTER
CFUHOURSACTIVITY
648LESSONS
ExamDate
GENNAIO27/01/2025
GENNAIO27/01/2025
Objectives
ACQUISITION OF BASIC KNOWLEDGE RELATING TO THE MAIN BIOCHEMICAL PROCESSES, UNDERSTANDING THE MOLECULAR STRUCTURE AND ORGANIZATION OF THE MAIN BIOMOLECULES, KNOWING THE BASIC ELEMENTS OF BIOENERGETICS AND THE GENERAL MEANING OF METABOLISM.
THE STUDENT WILL BE ABLE TO APPLY THE KNOWLEDGE TO ADDRESS THE STUDY AND UNDERSTANDING OF THE CHEMICAL NATURE AND THE STRUCTURE OF THE CONSTITUENTS OF LIVING MATTER, OF THE TRANSFORMATIONS OF BIOMOLECULES, AND BASIC KNOWLEDGE ON THE FUNCTIONING OF ENZYMES AND BIOENERGETICS. KNOWING HOW TO USE THE CONCEPTS LEARNED TO UNDERSTAND AND INTERPRET IN A LOGICAL WAY THE CHEMICAL-PHYSICAL PROPERTIES OF THE MAIN BIOLOGICAL MACROMOLECULES; USE THE KNOWLEDGE LEARNED TO SOLVE THEORETICAL PROBLEMS IN A LOGICAL AND DEDUCTIVE WAY. RECOGNIZING ANY ERRORS THROUGH A CRITICAL ANALYSIS OF THE METHOD APPLIED AND KNOWING HOW TO FORMULATE AND ARGUE SIMPLE ALTERNATIVE HYPOTHESESNDEPENDENCE OF JUDGMENT
AT THE END OF THE COURSE THE STUDENT WILL HAVE ACQUIRED CRITICAL SKILLS THAT ALLOW HIM TO CONTEXTUALIZE BIOCHEMICAL KNOWLEDGE AND APPLY IT IN EXPERIMENTAL LABORATORY PRACTICE.
COMMUNICATION SKILLS
THE STUDENT WILL BE ABLE TO SHARE THE KNOWLEDGE ACQUIRED THROUGH COMMUNICATION, USING APPROPRIATE SCIENTIFIC TERMINOLOGY, CLEARLY DEMONSTRATING FULL UNDERSTANDING AND MASTERY OF THE TOPICS COVERED.
LEARNING ABILITY
THE STUDENT WILL BE ABLE TO ACQUIRE A LEARNING METHOD THAT WILL ALLOW HIM TO PROCEED WITH HIS STUDIES INDEPENDENTLY AND CRITICALLY
Prerequisites
PREREQUISITES
FOR AN ADEQUATE UNDERSTANDING OF THE TOPICS COVERED IN THE COURSE, THE STUDENT MUST HAVE ACQUIRED THE OBJECTIVES RELATING TO THE FOLLOWING DISCIPLINES: BIOLOGY, GENERAL CHEMISTRY, ORGANIC CHEMISTRY.
Contents
COURSE CONTENTS
PROTEINS: AMINO ACIDS, THE PEPTIDE BOND (4 HOURS)
PRIMARY, SECONDARY, TERTIARY, AND QUATERNARY STRUCTURE OF PROTEINS (4 HOURS)
GLOBULAR PROTEINS, OXYGEN-BINDING PROTEINS: MYOGLOBIN AND HEMOGLOBIN (4 HOURS)
LIPID STRUCTURE, CLASSIFICATION AND PROPERTIES (2 HOURS)
FAT-SOLUBLE VITAMINS (2 HOURS)
PHOSPHOLIPIDS AND TRIGLYCERIDES (2 HOURS)
STEROIDS: CHOLESTEROL (2 HOURS)
ENZYMES ENZYMATIC REACTIONS AND FACTORS INFLUENCING CATALYSIS (4 HOURS)
CARBOHYDRATE STRUCTURE, CLASSIFICATION, FUNCTION. MONOSACCHARIDES, DISACCHARIDES, POLYSACCHARIDES (2 HOURS)
BIOENERGETICS AND METABOLISM: PRINCIPLES OF BIOENERGETICS, EXERGONIC AND ENDERGONIC REACTIONS (4 HOURS)
COMPOUNDS WITH HIGH ENERGY POTENTIAL: ROLE OF ATP AND OTHER PHOSPHORIC COMPOUNDS (2 HOURS)
THE FLOW OF ENERGY IN LIVING ORGANISMS: ATP-ADP CYCLE (2 HOURS)
GENERAL CONCEPTS OF METABOLISM. CARBOHYDRATE METABOLISM: GLYCOLYSIS, GLUCONEOGENESIS, AND GLYCOGEN METABOLISM (4 HOURS)
INTERMEDIATE METABOLISM: KREBS CYCLE, RESPIRATORY CHAIN, AND OXIDATIVE PHOSPHORYLATION (4 HOURS)
LIPID METABOLISM, BETA-OXIDATION (2 HOURS)
NITROGEN METABOLISM: PROTEIN CATABOLISM, UREA CYCLE (4 HOURS)
Teaching Methods
TEACHING METHODS
THE BIOCHEMISTRY COURSE INCLUDES 6 CREDITS (48 HOURS) AND WILL BE STRUCTURED THROUGH FRONTAL THEORETICAL LESSONS IN WHICH THE TOPICS OF THE COURSE ARE PRESENTED AND DISCUSSED, AND INTERACTIVE TEACHING. AS PER THE TEACHING REGULATIONS, ATTENDANCE AT THE GENERAL BIOCHEMISTRY COURSE MUST BE CONSIDERED COMPULSORY, THE PROCEDURES FOR VERIFYING ATTENDANCE WILL BE COMMUNICATED TO THE STUDENTS BY THE TEACHER AT THE BEGINNING OF THE COURSE.
Verification of learning
VERIFICATION OF LEARNING
ONGOING SELF-EVALUATION TESTS DURING THE COURSE USING BOTH MULTIPLE CHOICE AND OPEN-ENDED QUESTIONS, LASTING 45 MINUTES, AIMED AT EVALUATING UNDERSTANDING AND KNOWLEDGE OF THE TOPICS COVERED. THE FINAL TEST INCLUDES AN IN-DEPTH ORAL INTERVIEW LASTING A MINIMUM OF 30 MINUTES, AIMED AT EVALUATING THE STUDENT'S ABILITY TO COORDINATE AND CONTEXTUALIZE THE INFORMATION ACQUIRED, AS WELL AS VERIFYING THEIR ABILITY TO UNDERSTAND AND EXPRESS THEMSELVES USING APPROPRIATE TERMINOLOGY. THE FINAL GRADE, EXPRESSED IN THIRTIETHS, FROM 18/30 TO 30/30 CUM LAUDE, CONSIDERS THE KNOWLEDGE ACQUIRED REGARDING THE STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF THE MAIN CLASSES OF BIOMOLECULES, AND KNOWLEDGE REGARDING CELLULAR METABOLISM AND ITS REGULATION. FOR THE PURPOSES OF AWARDING HONORS, THE USE OF APPROPRIATE SCIENTIFIC LANGUAGE AND THE INDEPENDENCE OF JUDGMENT DEMONSTRATED WILL BE CONSIDERED.
Texts
RECENTLY PUBLISHED GENERAL BIOCHEMISTRY TEXTS
1) LEHNINGER A.L., NELSON D.L. & COX M.M. INTRODUZIONE ALLA BIOCHIMICA ED. ZANICHELLI
2) VOET E. & VOET J.G. BIOCHIMICA ED. ZANICHELLI
3) STAYER L. BIOCHIMICA ED. ZANICHELLI
More Information
OTHER INFORMATION
TEACHING LANGUAGE: ITALIAN
FREQUENCY MODE: MANDATORY
LOCATION: DEPARTMENT OF PHARMACIA
FOR FURTHER INFORMATION, PLEASE CONTACT PROF. ORNELLA MOLTEDO (MOLTEDO@UNISA:IT)
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