FARMACOGNOSIA

Sonia PIACENTE FARMACOGNOSIA

0760100020
DIPARTIMENTO DI FARMACIA
CORSO DI LAUREA MAGISTRALE A CICLO UNICO DI 5 ANNI
PHARMACY
2014/2015

OBBLIGATORIO
YEAR OF COURSE 4
YEAR OF DIDACTIC SYSTEM 2010
PRIMO SEMESTRE
CFUHOURSACTIVITY
540LESSONS
Objectives
THIS COURSE IS AIMED AT PROVIDING THE STUDENTS WITH A RATIONAL APPROACH TO CLASSIFY HERBAL DRUGS AND THEIR ACTIVE PRINCIPLES. THE STUDENT HAS TO DEMONSTRATE TO KNOW THE BASIC CRITERIA FOR THE IDENTIFICATION OF HERBAL DRUGS, FACTORS OF VARIABILITY, METHODS OF CONSERVATION AND EXTRACTION, ELEMENTS OF QUALITY CONTROL OF HERBAL DRUGS AND THEIR PREPARATION. FOR EACH HERBAL DRUG, PLANT SOURCE, MACROSCOPIC AND MICROSCOPIC CHARACTERS, CONSTITUENTS IN RELATION TO THEIR BIOSYNTHETIC ORIGIN, BIOACTIVITY AND THERAPEUTIC USES HAVE TO BE KNOWN.
STUDENTS SHOULD DEVELOP THE KNOWLEDGE BASE TO SUPPORT LIFELONG INTEREST AND LEARNING IN HERBAL DRUGS AND THEIR BIOACTIVE CONSTITUENTS AND SHOULD BE ABLE TO ASK QUESTIONS, DEVELOP HYPOTHESES AND OBSERVATIONS.
TO TRAIN THE STUDENT TO DEVELOP AND USE THEIR OWN INDEPENDENT JUDGMENT, THE INTERACTIONS AND OPPORTUNITIES FOR DISCUSSION WITH THE TEACHER AND WITH THE OTHER STUDENTS, WILL BE PROMOTED.
THE STUDENT SHOULD BE ABLE TO PRESENT AND JUSTIFY THE USE OF HERBAL DRUGS, THEIR PREPARATIONS AND THEIR SINGLE CONSTITUENTS AS MEDICINES OR HEALTH-PROMOTING AGENT. THEY WILL BE THOROUGHLY FAMILIAR WITH HERBAL REMEDIES AND WILL RESPOND CONFIDENTLY TO QUESTIONS CONCERNING THIS FIELD.
THE ACQUISITION OF A SPECIFIC LANGUAGE WHICH WILL BE CHECKED “IN ITINERE” AND DURING THE EXAMINATION WILL BE PROMOTED.
THE COURSE IS ALSO AIMED AT STIMULATING THE USE OF THE ACQUIRED KNOWLEDGES IN OTHER CONTEXTS AND AT ESTABLISHING LINKAGES WITH DIFFERENT SUBJECT MATTERS. THE STUDENTS WILL BE TRAINED TO USE AND CARRY OUT THE SCIENTIFIC METHOD AS A FUNDAMENTAL MECHANISM FOR CRITICAL ANALYSIS AND FOR SOLVING SPECIFIC PROBLEMS. THE COURSE IS ALSO AIMED AT PROMOTING STUDENTS' SELF-EVALUATION TO VERIFY THE ADEQUACY OF THE STUDY METHOD AND OF THE ACQUIRED KNOWLEDGES.
Prerequisites
KNOWLEDGES OF PHARMACEUTICAL BOTANY AND ORGANIC CHEMISTRY
Contents
DEFINITION OF PHARMACOGNOSY, HERBAL DRUG AND ACTIVE PRINCIPLE; PLANT NOMENCLATURE AND TAXONOMY. PLANTS AND THEIR STRUCTURES. ORGANIZED AND NOT ORGANIZED HERBAL DRUGS. EXTRACTIVE METHODS. CONSERVATION, STABILITY AND VARIABILITY OF HERBAL DRUGS AND DERIVED PREPARATIONS. ELEMENTS OF QUALITY CONTROL. SECONDARY METABOLITES AND RELATED BIOGENETIC PATHWAY: SHIKIMATE-, ACETATE- AND MEVALONATE PATHWAYS.FOR EACH HERBAL DRUG: BOTANICAL SOURCE, MACROSCOPIC AND MICROSCOPIC CHARACTERS, QUALI-QUANTITATIVE CHEMICAL PROFILE, BIOACTIVE CONSTITUENTS, BIOLOGICAL ACTIVITY, THERAPEUTIC USES. HERBAL DRUGS EMPLOYED FOR THEIR CONTENT IN CARBOHYDRATES, TERPENOIDS AND STEROIDS; ESSENTIAL OILS; RESINS AND GUMS, SAPONINS, CARDIAC GLYCOSIDES; AROMATIC COMPOUNDS, PHENOLS, TANNINS, FLAVONOIDS, COUMARINS, LIGNANS. ANTRAQUINONES. DRUGS EMPLOYED FOR THEIR CONTENT IN ALKALOIDS DERIVING FROM ORNITINE, LISINE, PHENYLALANINE, TYROXINE, AND TRYPTOFANE.
Teaching Methods
LECTURES, SEMINARS, TUTORIALS
Verification of learning
WRITTEN AND ORAL EXAMINATIONS. THE STUDENT WILL BE ASKED TO DISCUSS THE MAIN TOPICS OF THE COURSE, TRYING TO DEMONSTRATE CRITICAL THOUGHT AND AWARENESS OF THE STRUCTURE OF THE FIELD OF STUDY.
Texts
SAMUELSSON, FARMACOGNOSIA, EMSI.
P.M. DEWICK, CHIMICA, BIOSINTESI E BIOATTIVITÀ DELLE SOSTANZE NATURALI, PICCIN, PADOVA.
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