Sonia PIACENTE | PHYTOCHEMISTRY AND PHARMACOGNOSY
Sonia PIACENTE PHYTOCHEMISTRY AND PHARMACOGNOSY
cod. 0760200019
PHYTOCHEMISTRY AND PHARMACOGNOSY
| 0760200019 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY | |
| 2022/2023 |
| OBBLIGATORIO | |
| YEAR OF COURSE 3 | |
| YEAR OF DIDACTIC SYSTEM 2020 | |
| AUTUMN SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| BIO/15 | 9 | 72 | LESSONS |
| Objectives | |
|---|---|
| THE COURSE IS AIMED AT THE ACQUISITION OF KNOWLEDGE AND UNDERSTANDING OF THE MAIN PATHWAYS OF THE PLANT SECONDARY METABOLISM, OF THE CHEMICAL FEATURES AND THE BIOSYNTHESIS OF THE MAIN CLASSES OF PLANT SECONDARY METABOLITES, IN PARTICULAR OF BIOACTIVE PRINCIPLES OF PHARMACEUTICAL, NUTRACEUTICAL AND COSMETIC INTEREST. FURTHER AIMS ARE THE KNOWLEDGE AND UNDERSTANDING OF THE CLASSIFICATION OF HERBAL DRUGS, OF THEIR BIOLOGICAL ACTIVITY AND OF THEIR BIOACTIVE PRINCIPLES. THE STUDENT, ON THE BASIS OF THE ACQUIRED SKILLS, WILL BE ABLE TO ELABORATE CRITERIA TO RECOGNIZE THE HERBAL DRUGS AND TO EVALUATE AND ADDRESS PROBLEMS RELATED TO THEIR USE. |
| Prerequisites | |
|---|---|
| KNOWLEDGES OF PLANT BIOLOGY AND ORGANIC CHEMISTRY |
| Contents | |
|---|---|
| PLANT NOMENCLATURE AND TAXONOMY. PLANTS AND THEIR MORPHOLOGY. ORGANIZED AND NOT ORGANIZED HERBAL DRUGS. CONSERVATION AND EXTRACTION METHODS OF HERBAL DRUGS. MAIN FEATURES OF HERBAL DRUGS AND PREPARATIONS (4 H). FOR EACH HERBAL DRUG: BOTANICAL SOURCE, MACROSCOPIC AND MICROSCOPIC FEATURES, QUALI-QUANTITATIVE CHEMICAL PROFILE, BIOACTIVE CONSTITUENTS, BIOLOGICAL ACTIVITY. THERAPEUTIC USES OF HERBAL DRUGS INCLUDED IN PHARMACOPOEIA. PRIMARY AND SECONDARY PLANT METABOLISM (2 H). PLANT METABOLIC PATHWAYS: STRUCTURES, PROPERTIES AND CLASSIFICATION OF SECONDARY METABOLITES (3 H). EXTRACTION AND ISOLATION METHODS OF SECONDARY METABOLITES (2 H). CARBOHYDRATES IN PLANTS (2H) AND HERBAL DRUGS EMPLOYED FOR THEIR CONTENT IN CARBOHYDRATES (2 H). HERBAL DRUGS BASED ON GUMS, RESINS, GUM-RESINS AND BALSAMS (1 H) LIPIDS AND HERBAL DRUGS EMPLOYED FOR THEIR CONTENT IN LIPIDS (4 H). SHIKIMIC ACID PATHWAY: CHEMICAL FEATURES OF THE DIFFERENT CLASSES OF PHENOLIC COMPOUNDS (6 H). HERBAL DRUGS CONTAINING PHENOLICS, TANNINS, PHENYLPROPANOIDS, COUMARINS, LIGNANS (6 H). ACETATE PATHWAY: ANTRAQUINONES AND RELATIVE HERBAL DRUGS (2 H). COMPOUNDS WITH MIXED BIOGENESIS: FLAVONOIDS AND RESVERATROL AND THEIR BIOLOGICAL ACTIVITIES (2 H). MEVALONATE PATHWAY. TERPENE COMPOUNDS: MONOTERPENS, SESQUITERPENS, DITERPENS. HERBAL DRUGS EMPLOYED FOR THEIR CONTENT IN TERPENOIDS (ESSENTIAL OILS, SESQUITERPENES AND DITERPENES) (8 H) STEROIDS, TRITERPENE SAPONINS, STEROIDAL SAPONINS, CARDIAC GLYCOSIDES AND RELATED HERBAL DRUGS (8 H). ALKALOIDS AND THEIR BIOLOGICAL AND ECOLOGICAL ROLE IN PLANTS. CHEMICAL FEATURES AND CLASSIFICATION (2 H). ALKALOIDS DERIVED FROM ORNITHINE (2 H). ALKALOIDS DERIVED FROM LYSINE AND RELATED HERBAL DRUGS (2H). ALKALOIDS DERIVED FROM PHENYLALANINE AND TYROSINE AND RELATED HERBAL DRUGS (6 H). ALKALOIDS DERIVED FROM TRYPTOPHAN AND RELATED HERBAL DRUGS (6H). ALKALOIDS DERIVED FROM A MIXED PATHWAY AND RELATED HERBAL DRUGS (2 H). |
| Teaching Methods | |
|---|---|
| LECTURES, SEMINARS, TUTORIALS |
| Verification of learning | |
|---|---|
| THE EXAM CONSISTS OF A WRITTEN AND ORAL TEST, TO BE SUSTAINED IN THE SAME EXAM SESSION. THE RATING IS X/30. TO PASS THE WRITTEN TEST WITH A SCORE OF 18/30 IS MANDATORY TO ACCESS TO THE ORAL TEST AND REACH THE FINAL GRADE. THE WRITTEN TEST TAKES TWO HOURS AND CONSISTS OF OPEN QUESTIONS ON THE MAIN LEARNING OUTCOMES. EACH QUESTION IS ADDRESSED TO VERIFY KNOWLEDGES OF BOTH PHARMACOGNOSY AND PHYTOCHEMISTRY. THE STUDENT WILL BE ASKED TO DISCUSS THE MAIN TOPICS OF THE COURSE, TRYING TO DEMONSTRATE CRITICAL THOUGHT AND AWARENESS OF THE SUBJECTS OF THE FIELD OF STUDY. |
| Texts | |
|---|---|
| DEWICK PAUL M., CHIMICA, BIOSINTESI E BIOATTIVITÀ DELLE SOSTANZE NATURALI 2/ED.- EDIZIONE ITALIANA A CURA DI ERNESTO FATTORUSSO [DEWICK - PICCIN EDITORE] MANN J. CHEMICAL ASPECTS OF BIOSYNTHESIS, CHEMISTRY PRIMERS, OXFORD. MAZZANTI G., DELL'AGLI M, IZZO A.A. FARMACOGNOSIA E FITOTERAPIA BASI FARMACOLOGICHE E ASPETTI APPLICATIVI, PICCIN, PADOVA. G. SAMUELSSON FARMACOGNOSIA - FARMACI DI ORIGINE NATURALE. SECONDA EDIZIONE ITALIANA A CURA DI: F. CAPASSO, R. DE PASQUALE, I. MORELLI, CASA EDITRICE EMSI, ROMA. F. CAPASSO, R. DE PASQUALE, G. GRANDOLINI, N. MASCOLO. FARMACOGNOSIA: FARMACI NATURALI, LORO PREPARAZIONI ED IMPIEGO TERAPEUTICO, CASA EDITRICE: SPRINGER-VERLAG |
| More Information | |
|---|---|
| SONIA PIACENTE HTTP://WWW.UNISA.IT/DOCENTI/SONIAPIACENTE/INDEX |
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