Giovanna DELLA PORTA | REGENERATIVE MEDICINE IN THE MUSCULOSKELETAL SYSTEM: REALITY AND OPPORTUNITIES
Giovanna DELLA PORTA REGENERATIVE MEDICINE IN THE MUSCULOSKELETAL SYSTEM: REALITY AND OPPORTUNITIES
| 8803100012 | |
| DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA" | |
| P.H.D. COURSE | |
| TRANSLATIONAL MEDICINE FOR DEVELOPMENT AND ACTIVE AGING | |
| 2022/2023 |
| YEAR OF COURSE | |
| YEAR OF DIDACTIC SYSTEM 2020 | |
| FULL ACADEMIC YEAR |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| MED/33 | 1 | 6 | LESSONS |
| Objectives | |
|---|---|
| PROVIDE KNOWLEDGE OF THE TECHNOLOGIES USED IN TISSUE ENGINEERING. THE COURSE INTEGRATES THE BASIC KNOWLEDGE OF BIOMATERIALS, TRANSPORT PHENOMENA, BIOREACTOR AND TISSUE ENGINEERING WITH FUNDAMENTAL KNOWLEDGE OF CELLULAR AND MOLECULAR MECHANISMS FOR THE FABRICATION IN VITRO OF BIO-HYBRIDS TISSUE. |
| Prerequisites | |
|---|---|
| KNOWLEDGE OF CELLULAR AND MOLECULAR BIOLOGY, BIOCOMPATIBLE AND BIO-ABSORBABLE BIOMATERIALS, MECHANISMS OF CONTROLLED DELIVERY OF BIOMOLECULES AND DRUGS |
| Contents | |
|---|---|
| PART I: DEFINITIONS AND OVERVIEW OF TISSUE ENGINEERING. INNOVATIVE THERAPEUTIC APPROACH: CHALLENGES AND OPPORTUNITIES. CELL ORGANISATION IN HIGHER ORDER STRUCTURES: TISSUES AND ORGANS. CELL RESPONSE TO THE EXTERNAL ENVIRONMENT. DIFFERENTIATION AND TISSUE DEVELOPMENT. REPAIR AND REGENERATION. TISSUE REACTION TO PERMANENT IMPLANTS (PROSTHESES). STRUCTURE AND FUNCTIONS OF THE EXTRACELLULAR MATRIX AND CELL-MATERIAL INTERACTION. PART II. "SCAFFOLD-BASED" APPROACHES. DESIGN CRITERIA AND PROPERTIES OF BIOMATERIALS (POLYMERIC, CERAMIC, COMPOSITE) WITH A DESCRIPTION OF THE MOST COMMON MANUFACTURING TECHNIQUES. DESIGN AND PRODUCTION OF SCAFFOLDS FOR THE REGENERATION OF HARD AND SOFT TISSUES. OUTLINE OF CHARACTERIZATION TECHNIQUES. PART III. "CELL-BASED" AND "MORPHOGEN-BASED" APPROACHES EFFECTS OF MECHANICAL STIMULATION (BIOREACTORS). GENE TRANSFECTION. GROWTH FACTORS AND CONTROLLED RELEASE DEVICES. INTERSTITIAL TRANSPORT AND MICROENVIRONMENTAL CONTROL. DESIGN OF BIOREACTORS FOR TISSUE ENGINEERING.. PART IV. CLINICAL AND REGULATORY APPLICATIONS TISSUE ENGINEERING OF THE MUSCULOSKELETAL SYSTEM: BONES, CARTILAGE, TENDONS. REGULATORY ASPECTS OF TISSUE ENGINEERING PRODUCTS. SEMINARS/TESTIMONIALS FROM PROFESSIONALS IN THE FIELD. |
| Teaching Methods | |
|---|---|
| LESSONS AND EXERCISES. IN PARTICULAR, STUDENTS ARE ENCOURAGED TO IDENTIFY THE PROPERTIES OF THE MOST IMPORTANT MATERIALS FOR CERTAIN APPLICATIONS IN THE BIOMEDICAL FIELD AND TO REACH ORIGINAL AND AUTONOMOUS OPINIONS ON POSSIBLE SOLUTIONS TO CONCRETE PROBLEMS. |
| Verification of learning | |
|---|---|
| THE LEARNING TESTS INCLUDE IN ITINERE AND FINAL TEST WITH INTERVIEW. AT THE END OF THE COURSE, STUDENTS MUST: 1. POSSESS THE BASIC COGNITIVE TOOLS NECESSARY FOR UNDERSTANDING THE BASIC MECHANISMS OF TISSUE REGENERATION PROCESSES. 2. DEMONSTRATE THAT IT HAS ACQUIRED ADEQUATE KNOWLEDGE AND ASSESSMENT SKILLS FOR THE RESOLUTION INDEPENDENTLY OF CONCRETE PROBLEMS CONCERNING THE INTERACTION BETWEEN MATERIALS AND LIVING TISSUE. 3. DISCUSS, WITH ORIGINALITY AND AUTONOMY, ABOUT THE CELLULAR FUNCTIONS IN RELATION TO THEIR ABILITY TO IMPLEMENT REGENERATION PROCESSES. |
| Texts | |
|---|---|
| MATERIAL AND HANDOUTS PROVIDED BY THE TEACHER. MOZAFARI M., SEFAT F., ATALA A., HANDBOOK OF TISSUE ENGINEERING SCAFFOLDS: VOLUME ONE EDS ELSEVIER. ISBN (PRINT): 978-0-08-102563-5 ISBN (ONLINE): 978-0-08-102564-2 |
| More Information | |
|---|---|
| THE TEACHER RECEIVES BY APPOINTMENT TO BE AGREED BY EMAIL. |
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