PHYSICAL, CHEMICAL AND STATISTICAL BASIS

Francesco DE CARO PHYSICAL, CHEMICAL AND STATISTICAL BASIS

1012600001
DEPARTMENT OF MEDICINE, SURGERY AND DENTISTRY "SALERNITANA MEDICAL SCHOOL"
EQF6
DEGREE PROGRAMME IN BIOMEDICAL LABORATORY TECHNIQUES
2024/2025

OBBLIGATORIO
YEAR OF COURSE 1
YEAR OF DIDACTIC SYSTEM 2024
AUTUMN SEMESTER
CFUHOURSACTIVITY
1BASI FISICHE, CHIMICHE E STATISTICHE - MOD.FISICA MEDICA
224LESSONS
2BASI FISICHE, CHIMICHE E STATISTICHE - MOD. MISURE ELETTRICHE ED ELETTRONICHE
112LESSONS
3BASI FISICHE, CHIMICHE E STATISTICHE - MOD. STATISTICA MEDICA
224LESSONS
4BASI FISICHE, CHIMICHE E STATISTICHE - MOD. CHIMICA E PROPEDEUTICA BIOCHIMICA
224LESSONS
5BASI FISICHE, CHIMICHE E STATISTICHE - MOD. INFORMATICA
224LESSONS
Objectives
THE MAIN OBJECTIVE OF TEACHING IS TO PROVIDE STUDENTS WITH THE BASICS OF PHYSICS, APPLIED PHYSICS; CHEMISTRY, BIOCHEMISTRY AND STATISTICS TO EFFECTIVELY ADDRESS THE TOPICS OF THE COURSE OF STUDY.

KNOWLEDGE AND UNDERSTANDING -
THE TEACHING AIMS TO MAKE STUDENTS ACQUIRE KNOWLEDGE ABOUT:
- THE MAIN TOPICS OF PHYSICS, CHEMISTRY AND STATISTICS
- THE PRINCIPLES UNDERLYING THE OPERATION OF THE MAIN INSTRUMENTS USED IN BIOMEDICAL LABORATORIES
- MODELS FOR THE PROCESSING AND ANALYSIS OF EXPERIMENTAL DATA
- THE STRUCTURE OF THE MAIN MOLECULES OF BIOCHEMICAL INTEREST, CRITICAL UNDERSTANDING OF THE FIELDS OF APPLICABILITY OF THE MODELS AND LAWS STUDIED AND THE LIMITS OF VALIDITY AND APPLICABILITY IN REAL CONTEXTS

ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING -
AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO:
CORRECTLY APPLY THE MODELS AND METHODS OF PHYSICS, CHEMISTRY AND STATISTICS TO THE QUALITATIVE AND QUANTITATIVE DESCRIPTION OF REAL CASES IN THE INTERDISCIPLINARY CONTEXTS OF INTEREST FOR THE COURSE OF STUDIES, ALSO IN RELATION TO THEIR INTRINSIC APPROXIMATIONS.

AUTONOMY OF JUDGMENT –
AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO:
INTEGRATE THE NECESSARY KNOWLEDGE AND MANAGE THE COMPLEXITY OF INFORMATION IN THE APPLICATION OF KNOWLEDGE OF PHYSICS, CHEMISTRY AND STATISTICS.

COMMUNICATION SKILLS –
AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO:
EXPOSE THE PHYSICS, BIOCHEMISTRY AND STATISTICS TOPICS COVERED IN THE COURSE WITH PROPRIETY AND SIMPLICITY OF LANGUAGE, ALSO AIMED AT A CLEAR AND EFFECTIVE TRANSMISSION OF CONTENTS AND RESULTS IN INTERDISCIPLINARY CONTEXTS.

LEARNING ABILITY -

AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO:
BROADEN AND DEEPEN THE TOPICS OF PHYSICS, BIOCHEMISTRY AND STATISTICS AND THEIR INTERDISCIPLINARY APPLICATIONS INDEPENDENTLY.
Prerequisites
THE STUDENT MUST HAVE ACQUIRED BASIC KNOWLEDGE IN THE FIELD OF MATHEMATICS AND GEOMETRY PROVIDED BY NORMAL HIGH SCHOOL CURRICULA.
Contents
AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO:
CORRECTLY APPLY THE MODELS AND METHODS OF PHYSICS, CHEMISTRY AND STATISTICS TO THE QUALITATIVE AND QUANTITATIVE DESCRIPTION OF REAL CASES IN THE INTERDISCIPLINARY CONTEXTS OF INTEREST FOR THE COURSE OF STUDIES, ALSO IN RELATION TO THEIR INTRINSIC APPROXIMATIONS
- INTEGRATE THE NECESSARY KNOWLEDGE AND MANAGE THE COMPLEXITY OF INFORMATION IN THE APPLICATION OF KNOWLEDGE OF PHYSICS, CHEMISTRY AND STATISTICS
- EXPOSE THE PHYSICS, BIOCHEMISTRY AND STATISTICS TOPICS COVERED IN THE COURSE WITH OWNERSHIP AND SIMPLICITY OF LANGUAGE, ALSO AIMED AT A CLEAR AND EFFECTIVE TRANSMISSION OF CONTENTS AND RESULTS IN INTERDISCIPLINARY CONTEXTS
- BROADEN AND DEEPEN THE TOPICS OF PHYSICS, BIOCHEMISTRY AND STATISTICS AND THEIR INTERDISCIPLINARY APPLICATIONS INDEPENDENTLY

NOTIONS OF PHYSICS
ANALYSIS AND USE OF VECTORS FOR THE DESCRIPTION OF THE PHYSICAL QUANTITIES
STUDY OF KINEMATICS AND MOTION LAWS; PRINCIPLES OF DYNAMICS; WORK AND ENERGY; CONSERVATION LAWS: ENERGY AND MOMENTUM; PRINCIPLES OF FLUID MECHANICS; LAWS OF THERMODYNAMICS. ACOUSTICS AND GEOMETRICAL OPTICS.

CHEMISTRY AND PROPAEDEUTIC BIOCHEMISTRY MODULE (2 CFU; 24 HOURS)

1ST LESSON (2 HOURS) ATOMS AND MOLECULES: STRUCTURE AND PROPERTIES. ATOMIC MODELS. PERIODIC TABLE OF ELEMENTS. NUCLEAR CHEMISTRY AND RADIOACTIVITY. CHEMICAL BONDS

2ND LESSON (2 HOURS) STATES OF AGGREGATION OF MATTER AND CHANGE OF STATE. THERMODYNAMICS. FREE ENERGY AND BALANCE. BIOENERGETICS

3RD LESSON (2 HOURS) MIXTURES AND SOLUTIONS. SOLUBILITY. CONCENTRATION OF SOLUTIONS. THE COLLIGATIVE PROPERTIES OF SOLUTIONS. OSMOSIS AND OSMOTIC PRESSURE.

4TH LESSON (2 HOURS) CHEMICAL KINETICS. ARRHEIUS LAW. CATALYSTS. CHEMICAL BALANCE. PRINCIPLE OF MOBILE EQUILIBRIUM. MULTIPLE AND HETEROGENEOUS EQUILIBRIA. STEADY STATE.

5TH LESSON (2 HOURS) ACIDS, BASES AND SALTS. WATER DISSOCIATION. BUFFER SOLUTIONS. ELECTROCHEMISTRY. OXIDATIONS AND REDUCTIONS. ELECTROLYSIS

6TH LESSON (2 HOURS) MOLECULES OF BIOLOGICAL INTEREST. CARBON AND FUNCTIONAL GROUPS. HYDROCARBONS: NOMENCLATURE, PROPERTIES AND REACTIVITY OF ALKANES, ALKENES, ALKYNES, HETEROCYCLIC COMPOUNDS AND ALKYL HALIDES.

7TH LESSON (2 HOURS) FUNCTIONAL GROUPS CONTAINING HETEROATOMS: ALCOHOLS, THIOLS, ETHERS AND THIOETHERS, AMINES. ALDEHYDES AND KETONES: HEMIACETALS AND ACETALS. HEMIKETALS AND KETALS.

8TH LESSON (2 HOURS) CARBOXYLIC ACIDS AND DERIVATIVES: ACYL HALIDES, ANHYDRIDES, ESTERS, THIOESTERS AND AMIDES.

9TH LESSON (2 HOURS) CARBOHYDRATES. STEREOISOMERISM. MONOSACCHARIDES, OLIGOSACCHARIDES AND POLYSACCHARIDES. REDUCING AND NON-REDUCING SUGARS

10TH LESSON (2 HOURS) LIPIDS: GENERAL INFORMATION AND CLASSIFICATION. FATTY ACIDS. TRIGLYCERIDES. MEMBRANE LIPIDS.

11TH LESSON (2 HOURS) AMINO ACIDS AND PROTEINS. STRUCTURE AND PROPERTIES. PEPTIDE BOND. OLIGO- AND POLYPEPTIDES.

12TH LESSON (2 HOURS) NITROGENOUS BASES, NUCLEOSIDES AND NUCLEOTIDES. NUCLEIC ACIDS.

STATISTICS MODULE
DESCRIPTIVE STATISTICS: CHARACTER, INDIVIDUAL, UNIVERSE AND STATISTICAL SAMPLE. DESCRIPTIVE STATISTICS AND INFERENTIAL STATISTICS; SAMPLE CHARACTERISTICS (REPRESENTATIVENESS, NUMEROSITY); RANDOM SELECTION (RANDOM NUMBER TABLES). MEASUREMENT SCALES (NOMINAL, ORDINAL, NUMERICAL).
FREQUENCY DISTRIBUTIONS; NUMBER OF CLASSES; MODULE (CONSTANT OR VARIABLE); FREQUENCY DENSITY; CUMULATIVE FREQUENCY; PERCENTILES.
GRAPHICAL REPRESENTATION OF A FREQUENCY DISTRIBUTION.
SUMMARY INDICATORS: CENTRAL TREND INDEXES (ARITHMETIC MEAN, FASHION AND MEDIAN), VARIABILITY INDICES (RANGE, DEVIANCE, VARIANCE, STANDARD DEVIATION, COEFFICIENT OF VARIATION), DISTRIBUTION SHAPE INDICES.
PROBABILITY AND STATISTICAL INFERENCE. DEFINITIONS. ADDITIVE LAW AND MULTIPLICATIVE LAW OF PROBABILITIES; CONDITIONAL PROBABILITY; BAYES THEOREM.
DIAGNOSTIC TESTS; SENSITIVITY AND SPECIFICITY OF A TEST; POSITIVE AND NEGATIVE PREDICTIVE VALUE.
PROBABILITY DISTRIBUTIONS THEORETICAL, BINOMIAL,
OF POISSON, OF GAUSS; PARAMETERS; STANDARD DEVIATED NORMAL.
DISTRIBUTION OF SAMPLE AVERAGES. SAMPLING. STANDARD ERROR OF THE AVERAGE; CONFIDENCE INTERVAL. STATISTICAL TEST CONCEPT; HYPOTHESIS ZERO (HO) AND CHOICE OF THE ALTERNATIVE HYPOTHESIS (H1) (ONE-TAILED OR TWO-TAILED TEST); LEVEL OF SIGNIFICANCE.
PARAMETRIC TESTS: STUDENT'S T; ANALYSIS OF VARIANCE.
NON-PARAMETRIC. FREQUENCY ANALYSIS. EXPECTED FREQUENCIES BASED ON A HYPOTHESIS; CHI-SQUARE. TEST OF SIGNS. WILCOXON TEST
STUDY OF THE CONNECTION OF TWO QUANTITATIVE VARIABLES.
LINEAR CORRELATION. CORRELATION TABLES. CORRELATION COEFFICIENT
LINEAR REGRESSION. LEAST SQUARES PRINCIPLE; CALCULATION AND MEANING OF THE COEFFICIENTS OF THE REGRESSION LINE.
SURVIVAL ANALYSIS: KAPLAN MEIER METHOD
Teaching Methods
FRONTAL LESSONS
Verification of learning
WRITTEN AND ORAL EXAM
Texts
MATERIAL AND HANDOUTS PREPARED AND SHARED BY THE TEACHERS.
SUGGESTED REFERENCE BOOKS

PHYSICS
GIAN MARCO CONTESSA, GIUSEPPE AUGUSTO MARZO. FISICA APPLICATA ALLE SCIENZE MEDICHE. CASA EDITRICE AMBROSIANA (ZANICHELLI). ISBN: 9788808820327

CHEMISTRY AND BIOCHEMISTRY PROPEDEUTICS
TIZIANA BELLINI. CHIMICA E PROPEDEUTICA BIOCHIMICA. SECONDA EDIZIONE. ZANICHELLI

STATISTICS
MICHAEL C. WHITLOCK, DOLPH SCHLUTER. ANALISI STATISTICA DEI DATI BIOLOGICI. ZANICHELLI. ISBN: 9788808420145
More Information
Particular attention will be paid to coordination with the other courses of the course in order to guarantee harmonious and non-redundant training

  BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2024-11-18]