| CHEMICAL AND MECHANICAL METHODS FOR BIOACTIVE SECONDARY METABOLITE EXTRACTION FROM PLANT SOURCES. PRODUCTION OF PLANTS EXTRACTS (DRY, LIQUID AND SOFT) AND EVALUATION OF THEIR STABILITY. ESSENTIAL OILS. USE OF DRY EXTRACTS. CRUSHING METHODS BY DIFFERENT MILLS. POWDERS PARTICLE SIZE ANALYSIS. POWDER MIXING. DRY AND MOIST GRANULATION PROCEDURES. CAPSULES AND TABLETS: PREPARATION TECHNIQUES AND EXCIPIENTS. SOLUTIONS: ALCOHOLIC SOLUTIONS, OLEIC SOLUTIONS, GLYCERIC SOLUTIONS, ELIXIRS AND SYRUPS. SOLUTION CHEMICAL-PHYSIC CHARACTERISTICS. VEGETAL OILS. COLLOIDS, SUSPENSIONS AND EMULSIONS: DESCRIPTION, CHEMICAL-PHYSIC CHARACTERISTICS, INSTABILITY AND EXCIPIENTS. SEMI-SOLID PREPARATIONS FOR TOPICAL FORMULATIONS: PASTES, CREAMS, GELS AND POMADE. REHOLOGY. MAIN PATHWAYS FOR SYSTEMIC ASSUMPTION OF BIOACTIVE SUBSTANCES: ORAL ADMINISTRATION, TOPIC ADMINISTRATION, DERMAL AND TRANS-DERMAL ADMINISTRATION. BIOAVAILABILITY. TOPIC, ORAL AND TRANS-DERMAL CONTROLLED RELEASE DELIVERY SYSTEMS. CHARACTERISTICS, MECHANISMS OF ACTION: MASS TRANSFER IN MOVING FLUIDS, INTERFACIAL MASS TRANSFER. KINETICS OF DRUG RELEASE. LIPOSOMES AND LIPOSOMAL DRUG DELIVERY SYSTEMS. TDD AND TTS: CHARACTERISTICS, CLASSIFICATION, PREPARATION METHODS AND USE IN THE HERBAL MEDICINE FIELD. |
