Ciro MILITE | TOXICOLOGY CHEMISTRY
Ciro MILITE TOXICOLOGY CHEMISTRY
cod. 0760100038
TOXICOLOGY CHEMISTRY
| 0760100038 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACY | |
| 2018/2019 |
| YEAR OF COURSE 3 | |
| YEAR OF DIDACTIC SYSTEM 2016 | |
| PRIMO SEMESTRE |
| SSD | CFU | HOURS | ACTIVITY | |
|---|---|---|---|---|
| CHIM/08 | 5 | 40 | LESSONS |
| Objectives | |
|---|---|
| The course is aimed at acquiring knowledge and understanding of the chemical and toxicological aspects of the main tossicomanogene drugs and major metals responsible for poisoning. The student applying the acquired skills to be able to assess the level of toxicity and the risks of the substances object of the course. |
| Prerequisites | |
|---|---|
| IN ADDITION TO ALL THE COURSES OF THE 2ND YEAR, IT IS ALSO REQUIRED TO KNOW THE BASICS OF MEDICINAL CHEMISTRY I AND II |
| Contents | |
|---|---|
| INTRODUCTION - TOXICOLOGY AND TOXICOLOGICAL CHEMISTRY - KINDS OF TOXIC SUBSTANCES - EXPOSURE TO TOXIC SUBSTANCES - DOSE–RESPONSE RELATIONSHIPS AND RELATIVE TOXICITIES - KINETIC AND NONKINETIC TOXICOLOGY - PHASES OF TOXICITY - CHEMICAL NATURE OF TOXICANTS - BIOCHEMICAL TRANSFORMATIONS - PHASE I AND PHASE II METABOLIC REACTIONS OF XENOBIOTIC COMPOUNDS - BIOCHEMICAL MECHANISMS OF TOXICITY - CARCINOGENESIS AND MUTAGENESIS - TOXIC SUBSTANCES (ELEMENTS, INORGANIC COMPOUNDS, ORGANIC COMPOUNDS, ORGANOMETALLICS, NATURAL PRODUCTS) - ENVIRONMENTAL BIOLOGICAL PROCESSES AND ECOTOXICOLOGY - ANALYSIS OF XENOBIOTICS |
| Teaching Methods | |
|---|---|
| THE COURSE WILL INCLUDE LECTURES AND IN-CLASS DISCUSSIONS OF PRIMARY LITERATURE FOR A TOTAL OF 40 HOURS (5 CFU = 5 ECTS). |
| Verification of learning | |
|---|---|
| THE FINAL ORAL EXAMINATION WILL CONSIST OF IN-DEPTH QUESTIONS AND DISCUSSION OF THE TOPICS COVERED DURING THE COURSE. TO PASS THE EXAMINATION, THE STUDENT SHOULD OBTAIN A SCORE OF AT LEAST 18/30. |
| Texts | |
|---|---|
| S.E. MANAHAN, TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY, 3RDED., CRC PRESS CASARETT& DOULL, ELEMENTI DI TOSSICOLOGIA, CURTIS D. KLASSEN, JOHN B. WATKINS, CASA EDITRICE AMBROSIANA S.E. MANAHAN, TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY, 3RDED., CRC PRESS CASARETT& DOULL, ELEMENTI DI TOSSICOLOGIA, CURTIS D. KLASSEN, JOHN B. WATKINS, CASA EDITRICE AMBROSIANA |
| More Information | |
|---|---|
| THE COURSE WILL BE TAUGHT IN ITALIAN. ATTENDANCE IS HIGLY RECOMMENDED. FOR MORE INFORMATION, PLEASE CONTACT PROF. GIANLUCA SBARDELLA (GSBARDELLA@UNISA.IT) OR VISIT THE WEBSITE HTTP://DOCENTI.UNISA.IT/005059 |
BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2019-10-21]
