Alessandra FEOLI | Curriculum

Training

Alessandra Feoli graduated in Pharmaceutical Chemistry and Technology in 2011 at the University of Salerno.

She continued her training at the University of Salerno obtaining, in 2016, a PhD in Pharmaceutical Sciences with a thesis entitled “Biomolecular and biophysical approaches to interrogate epigenetic targets: a platform for drug discovery.”

Academic Positions and Research Experiences

In 2012 Alessandra Feoli spent a period as a visiting scientist at the laboratories of prof. Axel Imhof at the Ludwig-Maximilians-Universität München (LMU) in Munich (Germany) as part of the COST action “Epigenetics from bench to bedside” to deepen her knowledge in the biophysical and biochemical fields.

In 2015 Alessandra Feoli spent a period as a visiting scientist at the laboratories of Nanotemper technologies (Munich, Germany), a leading company in the development of innovative biophysical technologies such as Microscale Thermophoresis (MST) and nanoDSF.

From 2017 to 2019 she obtained a research grant at the Department of Pharmacy (University of Salerno) entitled "Development of a versatile screening platform for the identification of small molecule ligands for reader proteins of the post-translational methylation .”

From 2019 to 2020 she obtained a research grant at the Department of Pharmacy (University of Salerno) entitled "Development of techniques and methods for the early diagnosis of pathologies associated with childhood obesity."

From 2020 to 2021 she obtained a research grant at the Department of Pharmacy (University of Salerno) entitled "Development of analytical methods for the screening and characterization of the mechanism of action of small molecule inhibitors of GSK3β."

From 2021 to July 2023 she obtained a research grant at the Department of Pharmacy (University of Salerno) entitled “Advanced methods of Drug Discovery and ligand-protein studies.”

Since August 2023 you have been a Type A Researcher (RTD-A) at the Department of Pharmacy, University of Salerno.

Research activity

Development and application of biophysical methods (DSF, nanoDSF, SPR, MST) to study the interactions of small-molecule compounds with epigenetic and non-epigenetic proteins.

Development and application of biochemical methods (TR-FRET, Alphascreen, MMSA) for the evaluation of the inhibitory activity of small-molecule compounds with epigenetic and non-epigenetic targets.

Expression and purification of recombinant proteins in E.Coli.

Evaluation of the effect of small-molecule compounds in cell viability assays, cell cycle and western-blot assays.

Teaching activity

For the academic year 2022/2023 she was the holder of the Biophysical Methods and Techniques module of the doctoral course in Pharmaceutical Sciences (XXXVIII Cycle)