FOUNDATIONS OF PHARMACOLOGY AND GENERAL MEDICINE

Amelia FILIPPELLI FOUNDATIONS OF PHARMACOLOGY AND GENERAL MEDICINE

1012100013
DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA"
EQF6
NURSING
2019/2020

OBBLIGATORIO
YEAR OF COURSE 2
YEAR OF DIDACTIC SYSTEM 2013
PRIMO SEMESTRE
CFUHOURSACTIVITY
1FONDAMENTI DI FARMACOLOGIA E MEDICINA GENERALE - MOD FARMACOLOGIA
224LESSONS
2FONDAMENTI DI FARMACOLOGIA E MEDICINA GENERALE - MOD MEDICINA INTERNA
112LESSONS
3FONDAMENTI DI FARMACOLOGIA E MEDICINA GENERALE - MOD MEDICINA INTERNA
112LESSONS
4FONDAMENTI DI FARMACOLOGIA E MEDICINA GENERALE - MOD ANATOMIA PATOLOGICA
112LESSONS
5FONDAMENTI DI FARMACOLOGIA E MEDICINA GENERALE - MOD ONCOLOGIA
112LESSONS


Objectives
AT THE END OF THE COURSE THE STUDENT WILL BE ABLE TO:
-DESCRIBE THE PATHOPHYSIOLOGICAL PROCESSES AS WELL AS THE CLINICAL, DIAGNOSTIC AND THERAPEUTIC ELEMENTS IN MOST PREVALENT CONDITIONS IN INTERNAL MEDICINE AND ONCOLOGY
-DESCRIBE THE DIAGNOSTIC AND THERAPEUTIC PATH OF MEDICAL AND ONCOLOGICAL PATIENTS
-DESCRIBE THE MAJOR SIGNS AND SYMPTOMS ASSOCIATED TO THE PRESENCE OF MEDICAL AND ONCOLOGICAL CONDITIONS AND THEIR TREATMENT
-DESCRIBE THE MAIN PROBLEMS IN INTERNAL MEDICINE AND ONCOLOGY AND APPROPRIATE INTERVENTIONS BASED ON SCIENTIFIC EVIDENCE AND BASIC PATHOLOGICAL EVIDENCE
-DESCRIBE SUPPORTIVE CARE STRATEGIES IN DIFFERENT STAGES OF MEDICAL AND ONCOLOGICAL PATIENTS
-UNDERSTAND ESSENTIAL CONCEPTS TO FORMULATE AND ASSESS MEDICAL HISTORY TO DEVELOP DIAGNOSTIC HYPOTHESES IN INTERNAL MEDICINE AND ONCOLOGY
-DESCRIBE THE PRINCIPAL CLASSES OF DRUGS USED IN INTERNAL MEDICINE AND ONCOLOGY, THEIR THERAPEUTIC EFFECTIVENESS AND SIDE EFFECTS
-APPLY THE ACQUIRED KNOWLEDGE TO EVALUATE POTENTIAL PHARMACOLOGICAL THERAPIES IN INTERNAL MEDICINE AND ONCOLOGY, AND THEIR ROUTES AND MODALITIES OF ADMINISTRATION
Prerequisites
IT IS NECESSARY TO ACQUIRE THE CONCEPTS OF THE FOLLOWING DISCIPLINES: ANATOMY, BIOCHEMISTRY, GENERAL PATHOLOGY, PHYSIOLOGY, AND PATHOPHYSIOLOGY
Contents
PHARMACOLOGY
PHARMACODYNAMICS. PHARMACOKINETICS. ELEMENTS OF TOXICOLOGY. MOLECULAR PHARMACOLOGY. NEUROTRANSMISSION: THE AUTONOMIC AND SOMATIC MOTOR NERVOUS SYSTEMS. NEUROTRANSMISSION AND THE CENTRAL NERVOUS SYSTEM. MODULATION OF CARDIOVASCULAR AND RENAL FUNCTION AND VASCULAR VOLUME. INFLAMMATION AND IMMUNOMODULATION. DRUGS AFFECTING GASTROINTESTINAL FUNCTION. MEDICATIONS TO TREAT PAIN AND MUSCULOSKELETAL DISORDERS. CHEMOTHERAPY OF MICROBIAL AND NEOPLASTIC DISEASES.

INTERNAL MEDICINE
DIAGNOSIS: SIGNS AND SYMPTOMS. ANAMNESIS. PHYSICAL EXAMINATION. LABORATORY TESTS
EVIDENCE-BASED MEDICINE: ACUTE AND CHRONIC DISEASE. SENSITIVITY AND SPECIFICITY. PREVALENCE AND INCIDENCE. RISK FACTORS AND PREVENTION
RESPIRATORY DISEASES. COUGH. DYSPNEA. PNEUMONIA. COPD. ASTHMA. SPIROMETRY. EMOGASANALYSIS.
CARDIOVASCULAR AND RENAL DISEASE: MYOCARDIAL INFARCTION, ANGINA, ARRHYTHMIAS, HYPERTENSION. RENAL FAILURE.
ABDOMINAL PAIN: GASTROESOPHAGEAL REFLUX DISEASE. DYSPEPSIA, IRRITABLE BOWEL SYNDROME. CHRONIC INFLAMMATORY INTESTINAL DISEASES
LIVER DISEASE: LIVER FUNCTION. VIRAL HEPATITIS
ALLERGIC DISEASES: IGE-MEDIATED RESPONSES: HYPERSENSITIVITY, ALLERGY, ATOPY. ALLERGENS. MAIN CLINICAL PRESENTATIONS. RESPIRATORY ALLERGIES. FOOD ALLERGY. URTICARIA AND ANGIOEDEMA. SYSTEMIC ANAPHYLAXIS. SKIN TESTS, SERUM IGE, CHALLENGE TESTS. IMMUNOTHERAPY. ADVERSE DRUG REACTIONS: PSEUDOALLERGIC AND ALLERGIC
AUTOIMMUNE DISEASES: RHEUMATOID ARTHRITIS, SYSTEMIC LUPUS ERYTHEMATOSUS, SYSTEMIC SCLEROSIS, DERMATO-POLYMYOSITIS, SJOGREN'S DISEASE, ANTIPHOSPHOLIPID SYNDROME, VASCULITIS
FATIGUE: IRON METABOLISM AND ANEMIAS. INSOMNIA AND SLEEP DISORDERS. OSAS
METABOLIC DISEASE: BMI, OBESITY AND ENERGY BALANCE, METABOLIC SYNDROME, DIABETES, DYSLIPIDEMIAS, ENDOCRINE REGULATION

ONCOLOGY
-NEOPLASTIC TRANSFORMATION (TUMOR PROGRESSION, ONCOGENES, TUMOR SUPPRESSORS; PRINCIPLES OF EREDO-FAMILIARITY (3 H).
-NEOPLASTIC GROWTH AND CELL CYCLE: PRINCIPLES OF CANCER STAGING AND THERAPY (SURGERY, RADIOTHERAPY, ADJUVANT AND PALLIATIVE CHEMOTHERAPY). PREVENTION AND MANAGEMENT OF TOXICITIES IN ONCOLOGY (3 H).
-THE ROLE OF THE NURSE IN THE ONCOLOGY DEPARTMENT: THE RISK IN THE PRACTICE OF THE INFUSION (EXTRAVASATION). CENTRAL VENOUS ACCESSES (3 H).
-PALLIATION: PAIN THERAPY AND SUPPORT (3 H).

PATHOLOGY
THE LABORATORY OF PATHOLOGY. ELEMENTS OF GENERAL PATHOLOGY. THE TNM STAGING SYSTEM. THE DIGESTIVE SYSTEM. THE RESPIRATORY SYSTEM. THE UROGENITAL SYSTEM. BENIGN AND MALIGNANT TUMORS OF THE MAMMARY GLAND.
Teaching Methods
TEACHING CONSISTS OF 24 HOURS OF EDUCATION IN PHARMACOLOGY, 24 HOURS IN INTERNAL MEDICINE, 12 HOURS IN ONCOLOGY, AND 12 HOURS IN PATHOLOGY THROUGH FRONTAL LESSONS IN A CLASSROOM EQUIPPED WITH POWERPOINT PROJECTION. ATTENDANCE TO THE LESSONS IS MANDATORY. STUDENTS MUST ATTEND AT LEAST 75% OF PLANNED HOURS OF TEACHING IN ORDER TO TAKE THE FINAL EXAM. VERIFICATION OF STUDENT ATTENDANCE IS GENERALLY DONE ELECTRONICALLY OR ON A PAPER AS WELL AS BY THE TEACHER AT BEGINNING OF THE LESSON.
Verification of learning
ACHIEVEMENT OF THE OBJECTIVES OF TEACHING IS VERIFIED BY PASSING THE FINAL EXAM. THE FINAL EXAM CONSISTS OF AN ORAL TEST. THE ORAL TEST INCLUDES AN INTERVIEW WITH QUESTIONS AND DISCUSSION FOR ABOUT 30 MINUTES. IT IS IMPORTANT TO EVALUATE THE LEVEL OF KNOWLEDGE AND THE ABILITY OF ACHIEVED UNDERSTANDING OF THE STUDENTS ON THE TOPICS DISCUSSED DURING THE TEACHING AS WELL AS TO VERIFY THE ABILITY TO EXPRESS, UTILIZING THE APPROPRIATE TERMINOLOGY, AND TO ORGANIZE THE INTERVIEW ON THE THEORETICAL TOPICS. EACH EXAM IS EVALUATED IN A THIRTIETH SCORE SCALE AND IS PASSED WITH A MINIMUM SCORE OF 18/30.
Texts
NOTES FROM FRONTAL LESSONS

PHARMACOLOGY
• GOODMAN E GILMAN – LE BASI FARMACOLOGICHE DELLA TERAPIA. ZANICHELLI EDITORE, 2012.
• L. ANNUNZIATO, G. DI RIENZO - TRATTATO DI FARMACOLOGIA PER LE LAUREE TRIENNALI. IDELSON–GNOCCHI, 2016.
• F. ROSSI, V. CUOMO, C. RICCIARDI - FARMACOLOGIA: PRINCIPI DI BASE E APPLICAZIONI TERAPEUTICHE. EDIZIONE MINERVA MEDICA 2016.
• M. FURLANUT – FARMACOLOGIA GENERALE E CLINICA PER LE LAUREE SANITARIE. PICCIN NUOVA LIBRARIA, 2012.
• F. CLEMENTI, G. FUMAGALLI. FARMACOLOGIA GENERALE E MOLECOLARE. EDRA EDIZIONI, 2016.

INTERNAL MEDICINE
-ANTONELLI INCALZI, MEDICINA INTERNA PER SCIENZE INFERMIERISTICHE, PICCIN ED.
-AS SUPPORT TO THE MAIN TEXT: LESSON SLIDES AND PDFS PROVIDED DURING THE COURSE


ONCOLOGY
- CORE CURRICULUM ONCOLOGIA CLINICA. ANGELO R. BIANCO, SABINO DE PLACIDO, GIAMPAOLO TORTORA.
- ONCOLOGIA MEDICA. CIARDIELLO, ORDITURA, DE VITA, MORGILLO, TROIANI.

PATHOLOGY
-R ROBBINS, R.A. COTRAN, V. KUMAR: LE BASI PATOLOGICHE DELLE MALATTIE 2010, PICCIN, PADOVA
- L. RUCO, A. SCARPA :ANATOMIA PATOLOGICA : LE BASI. UTET, 2007, TORINO
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