INTERNAL MEDICINE - PHARMACOLOGY

Valeria CONTI INTERNAL MEDICINE - PHARMACOLOGY

1060100055
DEPARTMENT OF MEDICINE, SURGERY AND DENTISTRY "SALERNITANA MEDICAL SCHOOL"
EQF7
MEDICINE AND SURGERY
2024/2025

OBBLIGATORIO
YEAR OF COURSE 5
YEAR OF DIDACTIC SYSTEM 2016
SPRING SEMESTER
CFUHOURSACTIVITY
1MEDICINA INTERNA - FARMACOLOGIA - MOD MEDICINA INTERNA
448LESSONS
2MEDICINA INTERNA - FARMACOLOGIA - MOD MEDICINA GENERALE
112LESSONS
3MEDICINA INTERNA - FARMACOLOGIA - MOD MEDICINA GENERALE
112LESSONS
4MEDICINA INTERNA - FARMACOLOGIA - MOD FARMACOLOGIA
112LESSONS
5MEDICINA INTERNA - FARMACOLOGIA - MOD FARMACOLOGIA
112LESSONS
7MEDICINA INTERNA - FARMACOLOGIA - AFP FARMACOLOGIA
125INTERNAL STAGE
Objectives
THIS COURSE, STRUCTERED IN LESSONS, INTERACTIVE SESSIONS, PRACTICAL INTERACTIONS AND CASE DISCUSSION, HA STHE OBJECTIVE TO PROVIDE APPROPRIATE KNOWLEDGE TO ALLOW A CORRECT IDENTIFICATION, DIFFERENTIAL DIAGNOSIS AND FULL CLINICAL EVALUATION OF THE MAIN METABOLIC, DEGENERATIVE AND INFLAMMATORY DISEASES IN THE FIELD OF INTERNAL MEDICINE. THE INTEGRATED COURSE OF PHARMACOLOGY WILL GIVE FUNDAMENTAL TOOLS TO IMPLEMENT THE BEST PHARMACOLOGICAL APPROACH USED TO PREVENT AND TREAT THESE DISEASES AND TO MANAGE COMPLICATIONS OCCURRING DURING THE CLINICAL COURSE.
KNOWLEDGE AND UNDERSTANDING:
KNOWLEDGE OF THE TOPICS LISTED IN THE COURSE PROGRAM AND ACQUIREMENT OF THE APPROPRIATE TERMINOLOGY USED IN CLINICAL SETTINGS FOR THE MEDICAL BRANCHES INCLUDED IN THE INTEGRATED COURSE; UNDERSTANDING OF THE CELLULAR AND MOLECULAR BASIS OF MAJOR DISEASE IN INTERNAL MEDICINE; KNOWLEDGE AND UNDERSTANDING OF HOW TO COLLECT A DISEASE-SPECIFIC MEDICAL HISTORY, TO REQUEST/INTERPRET THE RELATED LABORATORY AND INSTRUMENTAL DIAGNOSTICS TO SET UP APPROPRIATE THERAPIES ALSO IN RELATION TO DIFFERENT STAGES OF LIFE AND OF GENDER MEDICINE.

APPLYING KNOWLEDGE AND UNDERSTANDING:
THE STUDENT WILL BE REQUIRED TO DEMONSTRATE THE ABILITY TO APPLY THE ACQUIRED KNOWLEDGE IN THE FOLLOWING INSTANCES: 1) RAISE THE DIAGNOSTIC SUSPICION OF MAIN CLINICAL SYNDROMES INCLUDING ADULT-ONSET RARE DISEASES AND ALSO IN RELATION TO DIFFERENT STAGES OF LIFE AND OF GENDER MEDICINE; 2) LEAD A CORRECT ANAMNESIS AND PHYSICAL EXAM ACCORDING TO CLINICAL PRESENTATIONS; 3) RECOGNIZE, DIAGNOSE AND EVALUATE THE MAIN SYMPTOMS AND CLINICAL PRESENTATIONS; 4) IDENTIFY THERAPEUTIC APPROACHES AND THEIR RATIONALE; 5) TRANSLATE THE KNOWLEDGE AND UNDERSTANDING OF THE DISEASES STUDIED IN EFFECTIVE COMMUNICATION WITH PATIENTS AND MEDICAL STAFF.

MAKING JUDGEMENTS:
THE STUDENT SHALL ACQUIRE THE ABILITY TO IMPROVE HIS/HER KNOWLEDGE THROUGH THE STUDY OF EXPERIMENTAL SYSTEMS AND COMPLEX CLINICAL CASES IN ORDER TO DEVELOP CRITICAL THINKING AND INDEPENDENT CLINICAL JUDGMENT

COMMUNICATION SKILLS:
THE STUDENT SHALL DEVELOP THE ABILITY TO EXPLAIN, IN SIMPLE, TERMINOLOGICALLY APPROPRIATE AND EXHAUSTIVE TERMS, THE ACQUIRED NOTIONS AND TERMINOLOGY

LEARNING SKILLS:
ON THE BASIS OF KNOWLEDGE ACQUIRED DURING THE MODULE AND WITH INDIVIDUAL STUDY, THE STUDENT SHALL EXHIBIT THE ABILITY TO UPDATE HER/HIS KNOWLEDGE BY READING AND UNDERSTANDING SCIENTIFIC PUBLICATIONS RELATED TO THE TOPIC OF THE COURSE.
Prerequisites
CLINICAL METHODOLOGY MEDICINE AND SURGERY;
GENERAL PATHOLOGY AND PHYSIOPATHOLOGY
MEDICAL PHARMACOLOGY AND TOXICOLOGY
Contents
INTERNAL MEDICINE

HYPERTENSION
SECONDARY HYPERTENSION
HEART FAILURE
ENDOCARDITIS
VALVULOPATHIES
ALCOHOLIC CARDIOMYOPATHY
HEMOPHILIA A E B
ACQUIRED HEMOPHILIA
VENOUS THROMBOEMBLISM
NON INVASIVE VENTILATION
GLOMERULONEPHRITIS
RENAL INSUFFICIENCY
THROMBOCYTOPENIAS
PURPURA
THROMBOTIC MICROANGIOPATHIES
DISSEMINATED INTRAVASCULAR COAGULATION
EDEMA AND ANGIOEDEMA
NEUROPATHIES IN INTERNAL MEDICINE
PRURITUS IN INTERNAL MEDICINE
HYPEREOSINOPHILIA
PRIMARY AND SECONDARY LYMPHEDEMA
PERICARDITIS AND SEROSITIS

PHARMACOLOGY

ANTIHYPERTENSIVE DRUGS
DIURETICS
CENTRALLY ACTING SYMPATHOLYTIC DRUGS
ADRENERGIC RECEPTOR ANTAGONISTS (BETA-BLOCKERS, ALPHA-BLOCKERS)
VASODILATORS
CALCIUM CHANNEL BLOCKERS
AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM

PHARMACOLOGICAL TREATMENT OF ISCHAEMIC HEART DISEASE
ANTIANGINAL AGENTS
DRUGS IN THE ACUTE CORONARY SYNDROME TREATMENT
DRUGS FOR THE TREATMENT OF PERIPHERAL VASCULOPATHIES AND CLAUDICATIO INTERMITTENS.

PHARMACOLOGICAL TREATMENT OF HEART FAILURE
INOTROPIC AGENTS
PHARMACOLOGICAL TREATMENT OF ACUTE HEART FAILURE
PHARMACOLOGICAL TREATMENT OF CHRONIC HEART FAILURE

ANTIARRHYTHMIC DRUGS

ANTITHROMBOTIC DRUGS
ANTIPLATELET DRUGS
ORAL ANTICOAGULANTS
PARENTERAL ANTICOAGULANTS
THROMBOLYTIC DRUGS

PHARMACOLOGICAL TREATMENT OF DYSLIPIDEMIA
STATINS
FIBRATES
BILE ACID SEQUESTRANTS
PCSK9 INHIBITORS

ANTI-DIABETIC DRUGS
INSULIN
ORAL HYPOGLYCEMIC AGENTS

PHARMACOLOGICAL TREATMENT OF GOUT
ANTI-HYPERURICEMIC DRUGS
TREATMENT OF ACUTE ATTACKS OF GOUT
Teaching Methods
FRONTAL LESSONS, LECTURES; EDUCATION SEMINARS; DISCUSSION OF CLINICAL CASES
Verification of learning
EXAM WITH EACH COURSE LECTURER OF THE INTEGRATED COURSE.

THE EXAM GRADE IS EXPRESSED IN THIRTIETHS.
COLLEGIAL EVALUATION OF THE MEMBERS OF THE EXAM COMMISSION.

Texts
RUGARLI C. MEDICINA INTERNA SISTEMATICA. VIII EDIZIONE, PICCIN EDITORE, 2022.

MANSOOR AM. MEDICINA INTERNA: DALLA CLINICA ALLA DIAGNOSI. PICCIN EDITORE, 2022

GOODMAN & GILMAN’S - LE BASI FARMACOLOGICHE DELLA TERAPIA – XIII EDIZIONE, A CURA DI LAURENCE L. BRUNTON, RANDA HILAL-DANDAN, BJÖRN C. KNOLLMANN – ZANICHELLI 2019;

FARMACOLOGIA - PRINCIPI DI BASE E APPLICAZIONI TERAPEUTICHE – IV EDIZIONE, A CURA DI F. ROSSI, V. CUOMO, C. RICCARDI, AAVV - MINERVA MEDICA 2019;

TRATTATO DI FARMACOLOGIA – II EDIZIONE, A CURA DI L. ANNUNZIATO, G. DI RIENZO – IDELSON-GNOCCHI 2016.
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