VERONICA DI SARNO | PHARMACEUTICAL ANALYSIS I
VERONICA DI SARNO PHARMACEUTICAL ANALYSIS I
cod. 0760200009
PHARMACEUTICAL ANALYSIS I
| 0760200009 | |
| DIPARTIMENTO DI FARMACIA | |
| EQF7 | |
| PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY | |
| 2022/2023 |
| OBBLIGATORIO | |
| YEAR OF COURSE 2 | |
| YEAR OF DIDACTIC SYSTEM 2020 | |
| AUTUMN SEMESTER |
| SSD | CFU | HOURS | ACTIVITY | ||
|---|---|---|---|---|---|
| LEZIONI FRONTALI MODULO DI ANALISI CHIMICO-FARMACEUTICA I | |||||
| CHIM/08 | 6 | 48 | LESSONS | ||
| ESERCITAZIONI LABORATORIO MODULO DI ANALISI CHIMICO-FARMACEUTICA I | |||||
| CHIM/08 | 4 | 48 | LAB | ||
| Objectives | |
|---|---|
| THE COURSE IS AIMED TO THE ACQUISITION OF KNOWLEDGE QUANTITATIVE DETERMINATION, THROUGH THE USE OF CHEMICAL AND PHYSICO- CHEMICAL TECHNIQUES, CLASSICAL AND INSTRUMENTAL, OF THE ORGANIC ACTIVE SUBSTANCES, WITH PARTICOLAR ATTENTION TO MENTIONED ITALIAN AND EUROPEAN PHARMACOPOEIA SUBSTANCES. AT THE END OF THE COURSE, THE STUDENT MUST DEMONSTRATE KNOWLEDGE OF LABORATORY EQUIPMENT AND THEIR USE, METHODS OF INTERPRETATION, ANALYSIS AND PRESENTATION OF DATA. ABILITY TO PERFORM THE MAIN LABORATORY OPERATIONS (FILTRATION, TITRATION, SPECTROSCOPIC-CHROMATOGRAPHIC ANALYSIS) IN ORDER TO SELECT THE MOST CORRECT METHOD FOR SOLVING THEORETICAL/PRACTICAL ANALYTICAL PROBLEMS FOR QUANTITATIVE DETERMINATION. |
| Prerequisites | |
|---|---|
| THE STUDENT MUST HAVE PASSED THE GENERAL AND INORGANIC CHEMISTRY, PHYSICS AND MATHEMATICS TEST. IN ADDITION, THE ACQUISITION OF THE ORGANIC CHEMISTRY COURSE AND A BASIC KNOWLEDGE OF THE ENGLISH LANGUAGE AND COMPUTER SCIENCE ARE STRONGLY RECOMMENDED. |
| Contents | |
|---|---|
| INTRODUCTION TO QUANTITATIVE CHEMISTRY, LABORATORY OPERATIONS, SAFETY IN LABORATORIES, GLASSWARE AND ITS USE (4H) ERRORS THEORY, HOW TO EXPRESS A RESULT, NUMERICAL VALUE, UNCERTAINTY, UNIT OF MEASURE, WORKING SCALE. UNIT OF CONCENTRATION. MOLARITY, NORMALITY, EQUIVALENTS. (4H) ANALYSIS OF THE PH OF STRONG AND WEAK ACIDS AND BASES. CALCULATION OF PH OF POLYPROTIC ACIDS AND THEIR SALTS. TITRATION CURVES OF ACIDS AND BASES. THEORY OF INDICATORS. MAIN ACID-BASE INDICATORS AND THEIR USE. PRIMARY STANDARDS, THEIR CHARACTERISTICS AND THEIR USE. STANDARD SOLUTIONS OF ACIDS AND BASES USED IN VOLUMETRIC ANALYSIS. EXAMPLES OF TITRATIONS ACCORDING TO E.P. (10H) SOLUBILITY. SOLUBILITY PRODUCT. PRECIPITATION AND REDISSOLUTION OF THE PRECIPITATES. COLLOIDAL AND CRYSTALLIN PRECIPITATES. (4H) TITRATION CURVES OF PRECIPITATION. DETERMINATION OF HALIDES ACCORDING TO MOHR, VOLHARD, FAJANS AND LIEBIG-DENIGES. PREPARATION OF STANDARD SOLUTIONS USED IN PRECIPITATION ANALYSIS. EXAMPLES OF DETERMINATIONS OF PRECIPITATION ACCORDING TO E.P.(6H) TITRATIONS IN NONAQUEOUS SOLVENTS: THEORY AND APPLICATIONS. (2H) COMPLEXOMETRIC TITRATION. METALLOCROMIC INDICATORS. COMPLEX-FORMATION AND INSTABILITY CONSTANTS. EXAMPLES OF COMPLEXOMETRIC TITRATIONS ACCORDING TO E.P. (4H) DEFINITION AND USE OF THE STANDARD REDUCTION POTENTIAL. REDOX INDICATORS AND SPECIFIC INDICATORS. (2H) PERMANGANOMETRY. IODIMETRY. IODOMETRY. CERIMETRY. BROMATOMETRY. PREPARATION OF STANDARD SOLUTIONS USED IN REDOX TITRATIONS. EXAMPLES OF DETERMINATIONS OF OXIDIZATION ACCORDING TO E.P. (10H) INSTRUMENTAL METHODS: UV / VIS SPECTROPHOTOMETRY, QUANTITATIVE ANALYSIS USING HIGH PERFORMANCE CHROMATOGRAPHY HPLC. (2H) |
| Teaching Methods | |
|---|---|
| THE TEACHING CONSISTS OF 96 HOURS OF LESSONS (10 CREDITS) DIVIDED INTO 48 HOURS OF LECTURES (6 CREDITS) AND 48 HOURS OF EXERCISES AND LABORATORY (4 CREDITS). LECTURES WILL BE HELD EVERY TWO WEEKS, FOCUSING ON SOLVING CALCULATION EXERCISES REGARDING THE TOPICS COVERED IN CLASS. IN ORDER TO ACCESS THE EXAM, THE STUDENT MUST TAKE AT LEAST 75% OF THE LABORATORY EXERCISES. |
| Verification of learning | |
|---|---|
| THE ACHIEVEMENT OF THE COURSE OBJECTIVES SHALL BE CERTIFIED BY PASSING A FINAL TEST WITH ASSESSMENT IN THIRTIES. THE TEST IS DIVIDED INTO THREE PROGRESSIVE AND SCHEDULED PHASES. FOR ACCESS TO THE NEXT STAGE IT IS MANDATORY TO PASS THE PREVIOUS TEST. THE FIRST TEST CONSISTS OF PASSING THE UNKNOWN LABORATORY TEST THAT CONCERNS THE RESOLUTION OF AN ANALYTICAL PROBLEM HAVING ITS SUBJECT TOPICS COVERED IN THE PRACTICAL EXERCISES. THE SECOND TEST CONSISTS IN THE RESOLUTION OF FIVE CALCULATION EXERCISES, TO PASS THE TEST THE CORRECT RESOLUTION OF AT LEAST THREE PROBLEMS IS REQUIRED. THE WRITTEN TEST HAS A DURATION OF TWO HOURS. THE THIRD PHASE CONCERNS THE PASSING OF AN ORAL EXAM THAT INCLUDES A DISCUSSION OF C. AT 20 MIN. AIMED AT ASSESSING THE LEVEL OF KNOWLEDGE AND UNDERSTANDING REACHED BY THE STUDENT ON THE THEORETICAL AND METHODOLOGICAL CONTENT INDICATED IN THE PROGRAM, AND VERIFYING COMMUNICATION SKILLS, LANGUAGE PROPERTIES AND ORGANIZATION OF THE ARGUMENT EXPOSURE |
| Texts | |
|---|---|
| SKOOG, WEST, HOLLER, CROUCH, FONDAMENTI DI CHIMICA ANALITICA, EDISES KOLTHOFF, SANDELL, MEEHAN, BRUCKENSTEIN, ANALISI CHIMICA QUANTITATIVA, PICCIN. WATSON, ANALISI FARMACEUTICA, EDISES KELLNER, MERMER, OTTO, WIDMER, CHIMICA ANALITICA, EDISES COZZI, PROTTI, RUARO, ANALISI CHIMICA STRUMENTALE, ZANICHELLI HARRIS D.C., CHIMICA ANALITICA QUANTITATIVA, ED. ZANICHELLI PORRETTA G.C., ANALISI DI PREPARAZIONI FARMACEUTICHE, ED. CISU NOVELLINO E., MARSEGLIA S., IACCARINO C., ANALISI CHIMICO FARMACEUTICA QUANTITATIVA |
| More Information | |
|---|---|
| LANGUAGE ITALIAN, THE LESSONS WILL TAKE PLACE AT THE DEPARTMENT OF PHARMACY FOR FURTHER INFO PLEASE SEND EMAIL TO THE TEACHER: ESOMMELLA@UNISA.IT/VDISARNO@UNISA.IT |
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